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| 1 | Tumor-secreted miR-214 induces regulatory T cells: a major link between immune evasion and tumor growth显示文摘 | Yuan Yin Xing Cai Xi Chen Hongwei Liang Yujing Zhang Jing Li Zuoyun Wang Xiulan Chen Wen Zhang Seiji Yokoyama Cheng Wang Liang Li Limin Li Dongxia Hou Lei Dong Tao Xu Takachika Hiroi Fuquan Yang Hongbin Ji Junfeng Zhang Ke Zen Chen-Yu Zhang | 2014 | Cell Research2014，24，10： | 33 |
| 2 | Major accident analysis and prevention of coal mines in China from the year of 1949 to 2009显示文摘From the year of 1949 to the present, the China national coal output has been increasing quickly and became first in the world in 2009. But at the same time, major coal mining accidents still exist nowadays. In order to review the overall situation and provide information on major accidents of coal mines in China, we investigated 26 major coal mining accidents in China between the years of 1949 and 2009 through statistical methods, each of which led to more than 100 fatalities. Statistical characteristics about accident-related factors such as time, death toll, accident reasons, characters and nature of enterprise were analyzed. And some special conclusions have been achieved. For example, although we have made great progress, the safety situation in China coal mining industry is still serious, and the reasons for the mining accidents are all human errors which are not inevitable. Such results may be helpful to prevent major accidents in coal mines. Moreso, based on both the knowledge of other countries which have good safety situation nowadays and the safety management situation of China, we made suggestion on safety management of China coal mining. In conclusion, countermeasures were proposed in accordance with the results of statistical studies and the analyses of problems existed in coal mines, including the perfec- tion of safety supervision organization, the establishment of cooperating agency among government, coal mines and workers, the perfection of safety rules and regulations, the improvement of safety investment, the enhancement of safety training, the development of safety technique, and the development of emer- gency rescue technique and equipment. | Wu Lirong Jiang Zhongan Cheng Weimin Zuo Xiuwei Lv Dawei Yao Yujing | 2011 | Mining Science and Technology2011，21，5： | 12 |
| 3 | Tissue-specific transcription reprogramming promotes liver metastasis of colorectal cancer显示文摘Metastasis,the development of secondary malignant growths at a distance from a primary tumor,is the cause of death for 90%of cancer patients,but little is known about how metastatic cancer cells adapt to and colonize new tissue environments.Here,using clinical samples,patient-derived xenograft(PDX)samples,PDX cells,and primary/metastatic cell lines,we discovered that liver metastatic colorectal cancer(CRC)cells lose their colon-specific gene transcription program yet gain a liver-specific gene transcription program.We showed that this transcription reprogramming is driven by a reshaped epigenetic landscape of both typical enhancers and super-enhancers.Further,we identified that the liver-specific transcription factors FOXA2 and HNF1A can bind to the gained enhancers and activate the liver-specific gene transcription,thereby driving CRC liver metastasis.Importantly,similar transcription reprogramming can be observed in multiple cancer types.Our data suggest that reprogrammed tissue-specific transcription promotes metastasis and should be targeted therapeutically. | Shuaishuai Teng Yang Eric Li Ming Yang Rui Qi Yiming Huang Qianyu Wang Yanmei Zhang Shanwen Chen Shasha Li Kequan Lin Yang Cao Qunsheng Ji Qingyang Gu Yujing Cheng Zai Chang Wei Guo Pengyuan Wang Ivan Garcia-Bassets Zhi John Lu Dong Wang | 2020 | Cell Research2020，30，1： | 11 |
| 4 | PtNi-W/C with Atomically Dispersed Tungsten Sites Toward Boosted ORR in Proton Exchange Membrane Fuel Cell Devices显示文摘The performance of proton exchange membrane fuel cells is heavily dependent on the microstructure of electrode catalyst especially at low catalyst loadings.This work shows a hybrid electrocatalyst consisting of PtNi-W alloy nanocrystals loaded on carbon surface with atomically dispersed W sites by a two-step straightforward method.Single-atomic W can be found on the carbon surface,which can form protonic acid sites and establish an extended proton transport network at the catalyst surface.When implemented in membrane electrode assembly as cathode at ultra-low loading of 0.05 mgPt cm^(−2),the peak power density of the cell is enhanced by 64.4%compared to that with the commercial Pt/C catalyst.The theoretical calculation suggests that the single-atomic W possesses a favorable energetics toward the formation of*OOH whereby the intermediates can be efficiently converted and further reduced to water,revealing a interfacial cascade catalysis facilitated by the single-atomic W.This work highlights a novel functional hybrid electrocatalyst design from the atomic level that enables to solve the bottle-neck issues at device level. | Huawei Wang Jialong Gao Changli Chen Wei Zhao Zihou Zhang Dong Li Ying Chen Chenyue Wang Cheng Zhu Xiaoxing Ke Jiajing Pei Juncai Dong Qi Chen Haibo Jin Maorong Chai Yujing Li | 2023 | Nano-Micro Letters2023，15，9： | 3 |
| 5 | Differential transcriptome analysis between Populus and its synthesized allotriploids driven by second-division restitution显示文摘In this report, we compared transcriptomic differences between a synthetic Populus section Tacamahaca triploid driven by second-division restitution and its parents using a high-throughput RNA-seq method. A total of 4,080 genes were differentially expressed between the high-growth vigor allotriploids(SDR-H) and their parents, and 719 genes were non-additively expressed in SDR-H. Differences in gene expression between the allotriploid and male parent were more signi ficant than those between the allotriploid and female parent, which may be caused by maternal effects. We observed3,559 differentially expressed genes(DEGs) between the SDR-H and male parent. Notably, the genes were mainly involved in metabolic process, cell proliferation, DNA methylation, cell division, and meristem and developmental growth. Among the1,056 DEGs between SDR-H and female parent, many genes were associated with metabolic process and carbon utilization.In addition, 1,789 DEGs between high- and low-growth vigor allotriploid were mainly associated with metabolic process,auxin poplar transport, and regulation of meristem growth.Our results indicated that the higher poplar ploidy level can generate extensive transcriptomic diversity compared with its parents. Overall, these results increased our understanding of the driving force for phenotypic variation and adaptation in allopolyploids driven by second-division restitution. | Shiping Cheng Zhen Huang Yun Li Ting Liao Yujing Suo Pingdong Zhang Jun Wang Xiangyang Kang | 2015 | Journal of Integrative Plant Biology2015，57，12： | 3 |
| 6 | Polarization microwave-induced thermoacoustic imaging for quantitative characterization of deep biological tissue microstructures显示文摘Polarization optical imaging can be used to characterize anisotropy in biological tissue microstructures and has been demonstrated to be a powerful tool for clinical diagnosis. However, the approach is limited by an inability to image targets deeper than ~1 mm due to strong optical scattering in biological tissues. As such, we propose a novel polarization microwave-induced thermoacoustic imaging(P-MTAI) technique to noninvasively detect variations in deep tissue by exploiting the thermoacoustic signals induced by four pulsed microwaves of varying polarization orientations. The proposed P-MTAI method overcomes the penetration limits of conventional polarization optical imaging and provides submillimeter resolution over depths of several centimeters. As part of the paper, the structural characteristics of tissues were quantified using a new parameter, the degree of microwave absorption anisotropy. P-MTAI was also applied to the noninvasive detection of morphological changes in cardiomyocytes as they transitioned from ordered to disordered states, providing a potential indication of myocardial infarction. | YUJING LI SHANXIANG ZHANG LINGHUA WU ZHONGWEN CHENG ZHENHUI ZHANG HAOHAO WANG SHUXIANG ZHAO MINGYANG REN SIHUA YANG DA XING HUAN QIN | 2022 | Photonics Research2022，10，5： | 2 |
| 7 | Serious BTEX pollution in rural area of the North China Plain during winter season显示文摘Atmospheric BTEX compounds(benzene, toluene, ethylbenzene and xylenes) in a rural site of the North China Plain(NCP) were preliminarily investigated in winter, and the outdoor concentrations(25.8–236.0 μg/m3) were found to be much higher than those reported in urban regions. The pollution of BTEX inside a farmer's house was even more serious, with combined concentrations of 254.5–1552.9 μg/m3. Based on the ratio of benzene to toluene(1.17 ± 0.34) measured, the serious BTEX pollution in the rural site was mainly ascribed to domestic coal combustion for heating during the winter season. With the enhancement of farmers' incomes in recent years, coal consumption by farmers in the NCP is rapidly increasing to keep their houses warm, and hence the serious air pollution in rural areas of the NCP during winter, including BTEX, should be paid great attention. | Kankan Liu Chenglong Zhang Ye Cheng Chengtang Liu Hongxing Zhang Gen Zhang Xu Sun Yujing Mu | 2015 | Journal of Environmental Sciences2015，27，4： | 2 |
| 8 | Biostratigraphy and systematics of Permian radiolarians显示文摘 | Wang Yujing Cheng Yennien Yang Qun | 1994 | Palaeoworld1994，4，： | 1 |
| 9 | Preparation of quaternarized N-halamine-grafted graphene oxide nanocomposites and synergetic antibacterial properties显示文摘At present,frequent outbreaks of bacteria and viruses have seriously affected people's normal lives.Therefore,the study of broad-spectrum antibacterial nanocomposites is very promising.However,most antibacterial materials have some disadvantages,such as single bactericidal mechanisms and unrepeatable use.Based on the current situation,a kind of nanocomposite with three structures of graphene oxide(GO),quaternary ammonium salt(QAs)and N-halamine was prepared,which showed synergistic effect to improve antibacterial activity and combined with a variety of sterilization mechanisms.Meanwhile,GO can provide richer ways of sterilization and high specific surface area,which is conducive to the grafting of quaternarized N-halamine.The advantages of physical sterilization of GO,charge adsorption of QAs,reuse of N-halamine and efficient sterilization are fully utilized.The results showed that the quaternarized N-halamine-grafted GO was obtained successfully.GO grafted with quaternarized N-halamine polymer showed strong speedy bactericidal activity against Escherichia coli(E.coli)and Staphylococcus aureus(S.aureus)(99%).It had good storage and regeneration properties. | Danlin Bu Yu Zhou Chang Yang Hengyu Feng Chunxia Cheng Mengjie Zhang Zice Xu Linghan Xiao Yujing Liu Zhenai Jin | 2021 | Chinese Chemical Letters2021，32，11： | 1 |
| 10 | Characteristics and anthropogenic sources of carbonyl sulfide in Beijing显示文摘Atmospheric mixing ratios of carbonyl sulfide(COS) in Beijing were intensively measured from March 2011 to June 2013. COS mixing ratios exhibited distinct seasonal variation, with a maximum average value of 849 ± 477 pptv in winter and a minimal value of 372 ± 115 pptv in summer. The seasonal variation of COS was mainly ascribed to the combined effects of vegetation uptake and anthropogenic emissions. Two types of significant linear correlations(R2> 0.66) were found between COS and CO during the periods from May to June and from October to March, with slopes(ΔCOS/ΔCO) of 0.72 and 0.14 pptv/ppbv, respectively. Based on the emission ratios of COS/CO from various sources, the dominant anthropogenic sources of COS in Beijing were found to be vehicle tire wear in summer and coal burning in winter. The total anthropogenic emission of COS in Beijing was roughly estimated as 0.53 ± 0.02 Gg/year based on the local CO emission inventory and the ΔCOS/ΔCO ratios. | Ye Cheng Chenglong Zhang Yuanyuan Zhang Hongxing Zhang Xu Sun Yujing Mu | 2015 | Journal of Environmental Sciences2015，27，2： | 1 |
| 11 | Research on field balancing of rotor显示文摘 | Chen Xuqin Jia Yujing Cheng Guangzhen | 2012 | Applied Mechanics and Materials2012，201，： | 1 |
| 12 | Anti-Parkinsonian Therapy:Strategies for Crossing the Blood–Brain Barrier and Nano-Biological Effects of Nanomaterials显示文摘Parkinson’s disease(PD),a neurodegenerative disease that shows a high incidence in older individuals,is becoming increasingly prevalent.Unfortunately,there is no clinical cure for PD,and novel anti-PD drugs are therefore urgently required.However,the selective permeability of the blood–brain barrier(BBB)poses a huge challenge in the development of such drugs.Fortunately,through strategies based on the physiological characteristics of the BBB and other modifications,including enhancement of BBB permeability,nanotechnology can offer a solution to this problem and facilitate drug delivery across the BBB.Although nanomaterials are often used as carriers for PD treatment,their biological activity is ignored.Several studies in recent years have shown that nanomaterials can improve PD symptoms via their own nano-bio effects.In this review,we first summarize the physiological features of the BBB and then discuss the design of appropriate brain-targeted delivery nanoplatforms for PD treatment.Subsequently,we highlight the emerging strategies for crossing the BBB and the development of novel nanomaterials with anti-PD nano-biological effects.Finally,we discuss the current challenges in nanomaterial-based PD treatment and the future trends in this field.Our review emphasizes the clinical value of nanotechnology in PD treatment based on recent patents and could guide researchers working in this area in the future. | Guowang Cheng Yujing Liu Rui Ma Guopan Cheng Yucheng Guan Xiaojia Chen Zhenfeng Wu Tongkai Chen | 2022 | Nano-Micro Letters2022，14，6： | 1 |
| 13 | Biostratigraphy and systematics of Permian radiolarians显示文摘 | Wang Yujing Cheng Yennien Yang Qun | 1994 | Palaeoworld1994，4，： | 1 |
| 14 | 婆婆纳属外来农田杂草生物入侵差异的关键生物学性状比较研究显示文摘婆婆纳属(Veronica)4种外来农田杂草——波斯婆婆纳(V.persica)、婆婆纳(V.didyma)、直立婆婆纳(V.arvensis)、睫毛婆婆纳(V.hederifolia)已在我国成功定植,但造成了不同的生态危害。目前,这4种外来农田杂草在不同光照条件下造成不同入侵程度的关键生物学性状尚不清楚。本研究对这4种外来物种的22个光合和繁殖性状进行了测定,同时对这些指标对其入侵水平的贡献强度进行了综合对比分析。野外调查结果表明,波斯婆婆纳的入侵水平最高,其次是婆婆纳、睫毛婆婆纳和直立婆婆纳。在这22个性状中,入侵水平的高低主要取决于它们的比叶重(光合相关参数)和不定根比例(无性繁殖性状)。而且,波斯婆婆纳能够适应较强的光照,同时也比婆婆纳属其它3个物种更耐荫。这4种外来农田杂草在不同光照条件下通过调整各器官生物量实现对光照的适应性分化,从而使得它们对作物具有不同的竞争力。由此可以推断,对光照条件的适应性和无性繁殖性状可使其成功入侵,并成为具有不同入侵程度的农田杂草。 | Yujing Liu Hairong Wu Congyan Wang Jiliang Cheng Sheng Qiang | 2023 | Journal of Plant Ecology2023，16，2： | 0 |
| 15 | Ultrasmall Coordination Polymers for Alleviating ROS-Mediated Inflammatory and Realizing Neuroprotection against Parkinson's Disease显示文摘Parkinson's disease(PD)is the second most common neurodegenerative disease globally,and there is currently no effective treatment for this condition.Excessive accumulation of reactive oxygen species(ROs)and neuroinflammation are major contributors to PD pathogenesis.Herein,ultrasmall nanoscale coordination polymers(NCPs)coordinated by ferric ions and natural product curcumin(Cur)were exploited,showing efficient neuroprotection by scavenging excessive radicals and suppressing neuroinflammation.In a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine(MPTP)-induced mouse PD model,such ultrasmall Fe-Cur NCPs with prolonged blood circulation and BBB traversing capability could effectively alleviate oxidative stress,mitochondrial dysfunction,and inflammatory condition in the midbrain and striatum to reduce PD symptoms.Thus,this study puts forth a unique type of therapeutics-based NCPs that could be used for safe and efficient treatment of PD with potential in clinical translation. | Guowang Cheng Xueliang Liu Yujing Liu Yao Liu Rui Ma Jingshan Luo Xinyi Zhou Zhenfeng Wu Zhuang Liu Tongkai Chen Yu Yang | 2022 | Research2022，，4： | 0 |
| 16 | Impacts of Changes in Structure of Rural Land Property Rights on Agricultural Performance显示文摘In the reform process of the rural land property rights system,the incentive mechanism of the rural land property rights system has a crucial impact on the production activities of rural economic entities.Due to the different rights structures of the property rights system in different social and economic development stages,the land rights and interests enjoyed by rural economic subjects are different,and the degree of incentives for farmers is also different.This difference in incentives affects farmers investment in agricultural production factors,which in turn affects agricultural performance.This paper analyzes the incentive impacts of the structure of rural land property rights on the changes of farmers land rights and agricultural performance since the founding of the People s Republic of China,in order to further deepen the reform of the land system,protect the rights and interests of farmers,promote the modernization of agriculture and rural areas,and explore the realization form and operation mechanism of the rural collective land system in the new era. | Yujing LI Yongfang YANG Yutian XIA Hao CHENG | 2023 | Asian Agricultural Research2023，15，3： | 0 |
| 17 | Improved interfacial adhesion for stable flexible inverted perovskite solar cells显示文摘Flexible perovskite solar cells have attracted widespread attention due to their unique advantages in lightweight,high flexibility,and easy deformation,which are suitable for portable electronics.However,the inverted(p-i-n)structured devices suffer from poor stability largely due to the low adhesion at the brittle interface(the hole transport layer/perovskite).Herein,zeolitic imidazolate framework-67(ZIF-67)is applied to inverted structured cells to optimize the interface and prolong the device lifetime.As a result,the flexible devices based on ZIF-67 obtain the champion power conversion efficiency of 20.16%.Over 1000 h under continuous light irradiation,the device retains 96%and 80%of its original efficiency without and with bias,respectively.Notably,devices show mechanical endurance with over 78%efficiency retention after 10,000 cycles of consecutive bending cycles(R=6 mm).The introduction of ZIF-67 suppresses the cracking in device bending,which results in improved environmental stability and bending durability. | Jie Dou Qizhen Song Yue Ma Hao Wang Guizhou Yuan Xueyuan Wei Xiuxiu Niu Sai Ma Xiaoyan Yang Jing Dou Shaocheng Liu Huanping Zhou Cheng Zhu Yihua Chen Yujing Li Yang Bai Qi Chen | 2023 | Journal of Energy Chemistry2023，，1： | 0 |
| 18 | Health Status and Food Intake Frequency of Elderly Residents During COVID-19 Community Closure—Jiangxia District,Wuhan City,China,2020显示文摘What is already known about this topic?Elderly persons are vulnerable to infectious diseases,and nutritional status and health conditions were important to evaluate for disease prevention and ability to recover for the elderly during the coronavirus disease 2019(COVID-19)pandemic.What is added by this report?In our study,a rapid assessment questionnaire was used to investigate the change of household life and dietary intake of the elderly(aged 60 years or more)during community closure.Food consumption frequency of aquatic food products,soybeans,and fresh fruits declined dramatically with reductions of 70.9%,70.9%,and 53.0%,respectively,and 49.6%of the elderly lived with chronic non-communicable diseases but had little knowledge of nutrition and health.What are the implications for public health practice?Community closure measures in Wuhan City have played a key role in cutting off the transmission route of COVID-19 and protecting vulnerable groups.As a high-risk population,the elderly should be advised to maintain and strengthen a balanced diet with proper nutrition through increasing intake of aquatic food products,soybeans,fruits,and vegetables,reducing total caloric intake,and decreasing oil and salt consumption.These measures will be significant for the elderly to reduce the risk of chronic disease complications and COVID-19 infection and to decrease the chance of critical illness. | Pengkun Song Cheng Li Ganyu Feng Jian Zhang Li Li Titi Yang Mingna Dong Ailing Liu Qi Zhang Yujing Liu Jinglei Wang Tanxi Ge Qing Yu Gangqiang Ding | 2020 | China CDC weekly2020，2，27： | 0 |
| 19 | Solvent-mediated handedness inversed and amplified circularly polarized luminescence system based on camptothecin derivative显示文摘To realize the handedness controllable circularly polarized luminescence(CPL) system remains challenging. Herein, the solvent-mediated CPL inversion and amplification systems were successfully constructed by camptothecin derivative(CPT-A). Due to the planar structure of N,N-dimethylformamide, it could coassemble with CPT-A, resulting in the alteration of g_(lum) from –0.0082 to +0.0085 by increasing water content. While in the non-planar solvent(hexafluoroisopropanol), the g_(lum) was amplified to 0.034 with the increase in water content. Moreover, the CPT-A could react with the glutathione, resulting in the anticancer drug CPT to make it more toxic to the cancer cells. Overall, the handedness controllable CPL systems were realized by tuning the supramolecular self-assembly of a prodrug. | Xuan Wu Ming Liu Cheng Zheng Yingying Wang Yujing Zheng Yuna Qian Zhiyong Liao Guoyong Fang Jianliang Shen | 2023 | Chinese Chemical Letters2023，34，2： | 0 |
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