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| 1 | SHRIMP single zircon U-Pb dating of the Kongling high-grade metamorphic terrain: Evidence for >3.2 Ga old continental crust in the Yangtze craton显示文摘Single zircons from two trondhjemitic gneisses and two clastic metasedimentary rocks without Eu anomaly of the Kongling high-grade metamorphic terrain are dated by the in situ SHRIMP U-Pb method. The results show that the trondhjemitic magma emplaced at 2947-2903 Ma. Concordant age of as old as 3.3 Ga is present in the detrital zircons from the clastic metasedimentary rocks. Together with the depleted mantle Nd model age (TDM =3.2-3.3 Ga) of the clastic metasedimentary rocks, this documents the presence of Paleoarchean continental crust in the Yangtze craton. | 高山 凌文黎 QIU Yumin Neal J.McNaughton David I.Groves | 2001 | Science China Earth Sciences2001，44，4： | 47 |
| 2 | 哈达门沟金矿床成岩成矿时代的定点定年研究显示文摘哈达门沟大型钾长石 -石英脉型金矿床位于华北地台北缘西段的乌拉山地区。矿区西部的大桦背花岗岩和矿区内的伟晶岩脉与金矿化均具有较为密切的空间关系 ,这导致不少研究者认为哈达门沟金矿床与大桦背岩体或伟晶岩之间也具有时间和成因联系。通过采用先进的高灵敏的高分辨率的离子探针 (SHRIMP)对大桦背岩体、伟晶岩脉和钾长石化蚀变岩进行的锆石 U- Pb定点定年研究表明 :伟晶岩脉形成于 (1836± 5)× 10 6a,属吕梁旋回 ;大桦背岩体形成于 (353± 7)× 10 6a,应为海西旋回早期产物 ;金矿化年龄小于或等于 (132± 2 )× 10 6a,应为燕山晚期。这些年龄结果说明 ,本区金矿化比大桦背岩体晚至少 2 2 0× 10 6a,这排除了金矿化与大桦背岩体和伟晶岩脉之间有任何成因联系的可能性。蚀变岩的年龄还证明 ,虽然乌拉山和胶东地区金矿床的围岩和年龄不同 ,但两地区的金矿化却几乎同时发生。此外 ,大桦背岩体的形成年龄与华北地块和蒙古古陆块碰撞作用发生的时间基本一致 ,因此大桦背岩体的 SHRIMP年龄为这一碰撞作用提供了可靠的年代学证据。 | 苗来成 Yumin Qiu 关康 Neal M cNaughton 裘有守 罗镇宽 David Groves | 2000 | 矿床地质2000，19，2： | 48 |
| 3 | 内蒙古乌拉山地区大桦背岩体SHRIMP锆石U-Pb年代学研究显示文摘大桦背花岗岩体位于内蒙古乌拉山地区,东距哈达门沟大型钾长石—石英金矿床约5km。前人对该岩体曾做过不少同位素年代学研究,所得结果相差较大,但是多数研究者认为大桦背岩体与区内金矿化具有成因联系。本文采用先进的高灵敏、高分辨率的离子探针(SHRIMP)对大桦背岩体进行了锆石U-Ph定点定年研究。结果表明,大桦背岩体的形成年龄为353±7Ma,应为海西旋回早期产物。此年龄比已得到的乌拉山金矿区成矿年龄大至少70Ma,因而推测大桦背岩体与金矿化之间不存在直接的成因联系。 | 苗来成 Yumin QIU 关康 Neal McNAUGHTON 裘有守 罗镇宽 David GROVES | 2001 | 地质论评2001，47，2： | 34 |
| 4 | 大别山英山和熊店榴辉岩单颗粒锆石SHRIMPU-Pb年代学研究显示文摘报道了对大别山高压 -超高压带河南罗山熊店和湖北英山蜜蜂尖两地榴辉岩单颗粒锆石SHRIMPU -Pb原位 (in situ)定年结果 .英山超高压榴辉岩年龄有 4组 :(773± 2 0 )Ma ,(73 0± 16)Ma ,(4 61± 7)Ma和 (2 62± 6)Ma ,其中以 (4 61± 7)Ma占绝对优势 .熊店高压榴辉岩有 3组年龄 :(4 4 9± 14 )Ma ,(3 0 7± 14 )Ma和 (2 16± 4)Ma .两地榴辉岩中均存在约 45 0Ma的早古生代奥陶纪年龄 ,它们均具有极低的Zr含量 (9× 10 - 6 ~ 19× 10 - 6 ) .结合熊店榴辉岩样品具有类似于MORB的微量元素特征和εNd值 (4 5 0Ma时为 + 6.5 6) ,说明该古生代年龄应代表古生代洋壳和岛弧物质俯冲经高压 -超高压变质作用的产物 .由于奥陶纪高压 -超高压事件的年龄同时出现在英山和熊店榴辉岩中 ,且熊店榴辉岩中清楚地记录了三叠纪高压-超高压事件 ,表明大别高压 -超高压带北界无论是在奥陶纪或三叠纪时均应在熊店榴辉岩以北的桐柏 | 高山 Yumin QIU 凌文黎 Neal J.McNaughton 张本仁 张国伟 张泽明 钟增球 索书田 | 2002 | 地球科学(中国地质大学学报)2002，27，5： | 27 |
| 5 | Glucocorticoid receptor and sequential P53 activation by dexamethasone mediates apoptosis and cell cycle arrest of osteoblastic MC3T3-E1 cells显示文摘 | Li Hui Yao Jianfeng Liu Hui Liu Shuguang Xu Peng Ma Jianbing Zhang Yumin | 2012 | 美中国际创伤杂志2012，11，1： | 22 |
| 6 | The Reference Genome Sequence of Scutellaria baicalensis Provides Insights into the Evolution of Wogonin Biosynthesis显示文摘Scutellaria baicalensis Georgi is important in Chinese traditional medicine where preparations of dried roots,'Huang Qin,' are used for liver and lung complaints and as complementary cancer treatments. We report a high-quality reference genome sequence for S. baicalensis where 93% of the 408.14-Mb genome has been assembled into nine pseudochromosomes with a super-N50 of 33.2 Mb. Comparison of this sequence with those of closely related species in the order Lamiales, sesamum indicum and Salvia splendens,revealed that a specialized metabolic pathway for the synthesis of 4'-deoxyflavone bioactives evolved in the genus Scu-tellaria. We found that the gene encoding a specific cinnamate coenzyme A ligase likely obtained its newfunc- tion following recent mutations, and that four genes encoding enzymes in the 4'-deoxyflavone pathway are present as tandem repeats in the genome of S. baicalensis. Further analyses revealed that gene duplications, segmental duplication, gene amplification, and point mutations coupled to gene neo- and subfunctionaliza-tions were involved in the evolution of 4'-deoxyflavone synthesis in the genus Scutellaria. Our study not only provides significant insight into the evolution of specific flavone biosynthetic pathways in the mint family, Lamiaceae, but also will facilitate the development of tools for enhancing bioactive productivity by metabolic engineering in microbes or by molecular breeding in plants. The reference genome of S. baicalensis is also useful for improving the genome assemblies for other members of the mint family and offers an important foundation for decoding the synthetic pathways of bioactive compounds in medicinal plants. | Qing Zhao Jun Yang Meng-Ying Cui Jie Liu Yumin Fang Mengxiao Yan Wenqing Qiu Huiwen Shang Zhicheng Xu Reheman Yidiresi Jing-Ke Weng Tomas Pluskal Marielle Vigouroux Burkhard Steuernagel Yukun Wei Lei Yang Yonghong Hu Xiao-Ya Chen Cathie Martin | 2019 | Molecular Plant2019，12，7： | 23 |
| 7 | Clinical features and treatment status of hemifacial spasm in China显示文摘 | Wang Lin Hu Xingyue Dong Hongjuan Wang Wenzhao Huang Yue Jin Lingjing Luo Yumin Zhang Weixi Lian Yajun Liang Zhanhua Shang Huifang Feng Yabo wu Yiwen Chen Jun Luo Weifeng Wan Xinhua | 2014 | Chinese Medical Journal2014，，5： | 20 |
| 8 | 重庆市环境友好型土地利用评价研究显示文摘研究目的:确定环境友好型土地利用的概念、评价指标体系和适宜的评价方法。研究方法:文献资料法、理论分析法、多指标综合评价法、组合评价法、统计检验法。研究结果:构建了一套包括40个指标、具有层次结构的环境友好型土地利用评价指标体系;确定变异系数法确定权重的TOPsIs评价方法为最优评价方法;重庆市计算结果表明,除2005年之外,土地利用的环境友好水平总体上呈逐年升高的趋势。研究结论:评价指标体系基本可以反映环境友好型土地利用的状态和水平;建立的指标体系和评价思路比较适合于环境友好型土地利用模式的评价;重庆市今后应从优化土地利用结构和提高资源利用效益两方面提高土地利用的环境友好水平。 | 杜加强 王金生 张桐 Yumin Chen 滕彦国 | 2008 | 中国土地科学2008，22，12： | 19 |
| 9 | Anti-inflammatory and anti-thrombogenic effects of atorvastatin in acute ischemic stroke显示文摘Atorvastatin decreases inflammation and thrombogenesis in patients with carotid artery plaque. Atorvastatin is administered to lower lipid levels, but its anti-inflammatory and anti-thrombogenic effects remain unclear. Eighty-nine patients from northeastern China with acute ischemic stroke caused by large-artery atherosclerosis were randomly divided into the study and control groups. All patients received routine treatment, including antiplatelet therapy, circulatory support, and symp-tomatic treatment. The study group (n=43) also received daily atorvastatin 20 mg/d, and the control group (n=46) received daily placebo pills containing glucose. After 4 weeks, the levels of C-reactive protein, fibrinogen, and D-dimer were significantly lower in the study group than in the control group. Decreases in the levels of C-reactive protein, fibrinogen, and D-dimer were not associated with de-creases in the levels of triacylglycerol and low-density lipoprotein cholesterol. These results suggest that atorvastatin reduces inflammation and thrombogenesis independent of its lipid-lowering effects in patients with acute ischemic stroke caused by large-artery atherosclerosis. | Lianqiu Min Shuai Shao Xiaoning Wu Lin Cong Ping Liu Haiping Zhao Yumin Luo | 2013 | Neural Regeneration Research2013，8，23： | 19 |
| 10 | The improved element-free Galerkin method for three-dimensional transient heat conduction problems显示文摘With the improved moving least-squares (IMLS) approximation, an orthogonal function system with a weight function is used as the basis function. The combination of the element-free Galerkin (EFG) method and the IMLS approximation leads to the development of the improved element-free Galerkin (IEFG) method. In this paper, the IEFG method is applied to study the partial differential equations that control the heat flow in three-dimensional space. With the IEFG technique, the Galerkin weak form is employed to develop the discretized system equations, and the penalty method is applied to impose the essential boundary conditions. The traditional difference method for two-point boundary value problems is selected for the time discretization. As the transient heat conduction equations and the boundary and initial conditions are time dependent, the scaling parameter, number of nodes and time step length are considered in a convergence study. | ZHANG Zan WANG JianFei CHENG YuMin LIEW Kim Meow | 2013 | Science China(Physics,Mechanics & Astronomy)2013，56，8： | 18 |
| 11 | Numerical Simulation of a Planing Vessel at High Speed显示文摘计划容器处于民用、军事的状况广泛地被使用。由于他们的高速度,计划容器的运动是复杂的。以便预言计划容器的运动,分析以高速度计划容器的水动力学表演是重要的。计算液体动态方法(CFD ) 被建议了计算计划容器的水动力学性能。在很传统的 CFD 途径,然而,模型测试或实验公式被需要在计算前获得计划容器的跑的态度。这份报纸论述一个新 CFD 方法计算计划容器的水动力学力量。数字方法基于平均 Reynolds 的海军司烧(RANS ) 方程。液体(VOF ) 的体积方法和 six-degrees-of-freedom 方程被使用。一个有效过程被介绍在数字模拟解决数字分叉问题。与试验性的结果相比,数字模拟结果显示跑的态度和水动力学性能能以高速度被预言很好。 | Yumin Su Qingtong Chen Hailong Shen Wei Lu | 2012 | Journal of Marine Science and Application2012，11，2： | 15 |
| 12 | Correlation between tongue manifestations and glucose, total cholesterol, and high-density lipoprotein cholesterol in patients with acute cerebral infarction显示文摘OBJECTIVE: To analyze the association between tongue manifestations and the levels of glucose (GLU), total cholesterol(TCH), and high-density lipoprotein cholesterol(HDL-C) in subjects with acute cerebral infarction.METHODS: Hospitalized patients with first unilateral cerebral infarction in the Neurological Department of Xuanwu Hospital were included and the correlation between tongue fur color, fur nature,and the levels of GLU,TCH, HDL-C were analyzed.RESULTS: HDL level in the thin fur group was higher than that in the thick fur group(P=0.02). The difference in the levels of GLU,TCH, and HDL-C among the groups was significant(P<0.05), classified in terms of slippery, moist, and dry fur. Further comparison between the groups by Student-Newman-Keuls test showed that GLU level in the dry fur group was the highest. Moreover, the TCH level in the slippery fur group was higher than the other two groups.CONCLUSION: A correlation between tongue manifestations and GLU, TCH, HDL-C was identified in the patients with acute cerebral infarction. | Ping Liu Li Gao Juexian Song Haiping Zhao XiaoguangWu Liyuan Huang Pingping Wang Yumin Luo | 2014 | Journal of Traditional Chinese Medicine2014，34，2： | 14 |
| 13 | RANSE Simulation of High-speed Planning Craft in Regular Waves显示文摘这份报纸在计划航行在常规波浪的手艺的数字模拟上论述研究。这允许保留高速度手艺的性能的海的精确估计。模拟集合在自由运动六度基于雷纳兹平均 Navier 司烧液体(RANSE VOF ) 的方程体积解答者。整修网孔技术和不可分的动态网孔方法被用来保证水动力学力量的好精确性和数字模拟的高效率。事件头波浪,倾斜的波浪和横梁波浪与三不同速度在模拟被产生(Fn =1.0, 1.5, 2.0 ) 。与波浪让计划手艺的性能来自不同方向的运动和海在流动解答者被显示。轮船设计者在驾驶在造高速度手艺的配置计划手艺的振幅和压力分发上把一个重音放在波浪的效果上。 | Shuo Wang Yumin Su Xi Zhang Jinglei Yang | 2012 | Journal of Marine Science and Application2012，11，4： | 13 |
| 14 | Regulation of Seed Vigor by Manipulation of Raffinose Family Oligosaccharides in Maize and Arabidopsis thaliana显示文摘棉白糖家庭 oligosaccharides (RFO ) 在许多植物种类在成熟干燥期间在种子积累。然而, RFO 是否在建立种子活力有一个角色,仍然保持不清楚。GALACTINOL SYNTHASE (GOLS ) ,棉白糖 SYNTHASE (RS ) ,和 STACHYOSE SYNTHASE (圣) 是为 RFO 负责的酶 ? 在植物的生合成。有趣地,仅仅棉白糖在玉米种子被检测,并且唯一的玉米 RS 基因(ZmRS ) 被识别。在这研究,我们发现二独立 mutator (亩) 打断了 zmrs 线,不包含棉白糖但是 hyperaccumulating galactinol, ? 显著地减少了种子活力,与空 segregant 控制相比。不同于玉米, Arabidopsis thaliana 种子包含几 RFO (棉白糖, stachyose,和 verbascose ) 。A 的操作。thaliana RFO ? 由 overexpressing ZmGOLS2, ZmRS,或 AtSTS 的内容表明了那 co-overexpression ZmGOLS2 和 ZmRS,或 ZmGOLS2 的 overexpression 独自一个,显著地增加了 RFO 的全部的内容并且提高了 Arabidopsis 种子活力。令人惊讶地,当 ZmRS 的 overexpression 增加了种子棉白糖内容时,它的 overexpression 戏剧性地减少了种子活力并且减少了 galactinol, stachyose,和 verbascose 的种子数量。相反, atrs5 异种种子类似于关于种子活力和 RFO 内容的野类型的那些,除了 stachyose 它在 atrs5 种子积累了。全部的 RFO, RFO/sucrose 比率,然而并非绝对单个 RFO ? 数量,断然与 A 相关。thaliana 种子活力, stachyose 和 verbascose 多于棉白糖作出贡献到。一起拿,这些结果提供新卓见进种子活力的规章的机制并且在 monocot 和 dicot 在 modulating 种子活力为 RFO 揭示不同要求。 | Tao Li Yumin Zhang Dong Wang Ying Liu Lynnette M.A. Dirk Jack Goodman A. Bruce Downie Jianmin Wang Guoying Wang Tianyong Zhao | 2017 | Molecular Plant2017，10，12： | 13 |
| 15 | Mitochondrial calcium uniporter protein MCU is involved in oxidative stress-induced cell death显示文摘Mitochondrial 钙 uniporter (MCU ) 是在在真核细胞的房间的 mitochondrial 的保存 Ca 2+ transporter。然而,在氧化导致压力的房间死亡的 MCU 蛋白质的角色仍然保持不清楚。这里,我们证明宫外地表示的 MCU 是在局部性的 mitochondrial HeLa 和主要小脑的小粒神经原(CGN ) 。内长的 MCU 减少 mitochondrial Ca 2+ 举起追随者组织安刺激击倒并且稀释氧化应力在 HeLa 房间和 CGN 导致的房间死亡。我们也发现 MCU 与 VDAC1 交往并且调停在 CGN 的 VDAC1 导致 overexpression 的房间死亡。这发现证明那 MCU-VDAC1 建筑群调整 mitochondrial Ca 2+ 举起和氧化导致压力的 apoptosis,它可能表示为氧化应力的治疗学的目标联系了疾病。 | Yajin Liao Yumin Hao Hong Chen Qing He Zengqiang Yuan Jinbo Cheng | 2015 | Protein & Cell2015，6，6： | 12 |
| 16 | Design and development of an oral remdesivir derivative W116 against SARS-CoV-2显示文摘Dear Editor,Since the declaration of COVID-19 as a global pandemic on March 11,2020,this pandemic has been circulating for 17 months throughout the world,leading to more than 200 million infections and nearly 4.4 million deaths as of August 15,2021.The pathogen of COVID-19 is a novel coronavirus named SARS-CoV-2,which shares-79%genome sequence identity with SARS-CoV.1 At the early stage of the COVID-19 outbreak,5ARS-CoV-2 caused great panic in the hardest-hit areas due to its high transmissibility and pathogenicity.To fight the COVID-19 crisis,drug repurposing was immediately pursued in order to find potential therapeutics. | Yuanchao Xie Wanchao Yin Yumin Zhang Weijuan Shang Zhen Wang Xiaodong Luan Guanghui Tian Haji A.Aisa Yechun Xu Gengfu Xiao Jia Li Hualiang Jiang Shuyang Zhanq Leike Zhang H.Eric Xu Jingshan Shen | 2021 | Cell Research2021，31，11： | 12 |
| 17 | Characterization of PM_(2.5)/PM_(2.5-10) and source tracking in the juncture belt between urban and rural areas of Beijing显示文摘Coarse (PM2.5-10) and fine (PM2.5) atmospheric particulate samples were collected in summer and winter during 2005―2007 in the juncture belt between urban and rural areas of Beijing. Elements, ions, organic/elemental carbon (OC/EC) and polynuclear aromatic hydrocarbons (PAHs) were determined to obtain some latest information about the particulate pollution in the juncture belt of Beijing. Particulate matter levels at this site were high as compared with the levels at other sampling sites in Beijing. Pollution elements, secondary ions and PAHs were enriched in fine particles rather than in coarse particles. An obvious seasonal variation of the chemical composition of PM was observed. Source apportionment results showed that secondary components were the largest mass contributor of PM2.5, accounting for 28%; whereas soil-related sources were the largest contributor of PM2.5-10, explaining about 49% of the total mass. The abnormal levels of soil heavy metals at the electronic waste disassembly site in the upwind villages suggested the potential impact of such activities to the environment. | WANG HaiLin ZHOU YuMin ZHUANG YaHui WANG XiaoKe HAO ZhengPing | 2009 | Chinese Science Bulletin2009，54，14： | 11 |
| 18 | Enabling practical electrocatalyst-assisted photoelectro- chemical water splitting with earth abundant materials显示文摘 | Xiaogang Yang Rui Liu Yumin He James Thorne Zhi Zheng Dunwei Wang | 2015 | Nano Research2015，8，1： | 11 |
| 19 | Photodegradation of methyl orange by BiOI-sensitized TiO_2显示文摘BiOI-sensitized titanium dioxide (TiO2) photocatalysts were prepared by a deposition method at room temperature and characterized by X-ray diffraction, X-ray photoelectron spectroscopy, and Brunauer-Emmett-Teller surface area measurements. The photocatalytic activities of the catalysts were evaluated for the degradation of methyl orange (MO) solution under UV and visible light irradiation. The effects of catalyst amount, initial pH value, initial concentration of MO, as well as KI amount were investigated. The repeatability of photocatalytic activity of the 1.7% BiOI/TiO2 catalyst was also tested. It is shown that BiOI sensitization enhances the photocatalytic activities of TiO2. With BiOI content increasing, the photocatalytic activities of BiOI/TiO2 under UV and visible light irradiation first increase, reaching a maximum around BiOI content of 1.7%, and then decrease with further increasing BiOI content. The 1.7% BiOI/TiO2 catalyst obviously exhibits much higher visible light photocatalytic activity than P25, and its UV light photocatalytic activity is slightly higher than that of P25. Under the conditions of a catalytic dose of 1.5 g.L-1, initial pH of 3.0, initial MO concentration of 20 mg.L-1, UV power of 300 W, and air flow rate of 0.8 L.min-1, complete degradatio is achieved within 60 min. The repeatability of photocatalytic activity of the 1.7% BiOI/TiO2 catalyst is highly reliable. | Li Huiquan Cui Yumin Hong Wenshan Hua Lin Tao Dongliang | 2012 | Rare Metals2012，31，6： | 10 |
| 20 | Numerical Study of Propulsion Mechanism for Oscillating Rigid and Flexible Tuna-Tails显示文摘 | Liang Yang Yumin Su Qing xiao | 2011 | Journal of Bionic Engineering2011，8，4： | 9 |
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