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| 1 | Commissioning progress of the FAST显示文摘The Five-hundred-meter Aperture Spherical radio Telescope(FAST) was completed with its main structure installed on September 25, 2016, after which it entered the commissioning phase. This paper aims to introduce the commissioning progress of the FAST over the past two years. To improve its operational reliability and ensure effective observation time, FAST has been equipped with a real-time information system for the active reflector system and hierarchical commissioning scheme for the feed support system, which ultimately achieves safe operation of the two systems. For meeting the high-performance indices, a highprecision measurement system was set up based on the effective control methods that were implemented for the active reflector system and feed support system. Since the commissioning of the FAST, a low-frequency ultra-wideband receiver and 19-beam1.05-1.45 GHz receiver have been mainly used. Telescope efficiency, pointing accuracy, and system noise temperature were completely tested and ultimately achieved the acceptance indices of the telescope. The FAST has been in the process of national acceptance preparations and has begun to search for pulsars. In the future, it will still strive to improve its capabilities and expand its application prospects. | Peng Jiang YouLing Yue HengQian Gan Rui Yao Hui Li GaoFeng Pan JingHai Sun DongJun Yu HongFei Liu NingYu Tang Lei Qian JiGuang Lu Jun Yan Bo Peng ShuXin Zhang QiMing Wang Qi Li Di Li | 2019 | Science China(Physics,Mechanics & Astronomy)2019，62，5： | 11 |
| 2 | Angular response of ‘pin-hole' imaging structure measured by collimated β source显示文摘The pitch-angle distribution of energetic particles is important for space physics studies on magnetic storm and particle acceleration.A‘pin-hole’imaging structure is built with the‘pin-hole’technique and a position sensitive detector,which can be used to measure the pitch angle distribution of energetic particles.To calibrate the angular response of the‘pin-hole’imaging structure,special experiment facilities are needed,such as the particle accelerator with special design.The features of this kind of particle accelerator are:1)The energy range of the outgoing particles should be mid-energy particles(tens keV to several hundred keV);2)the particle flux should be consistent in time-scale;3)the directions of the outgoing particles should be the same and 4)the particle number within the spot should be low enough.In this paper,a method to calibrate the angular response of the‘pin-hole’imaging structure by the90Sr/90Y β source with a collimator is introduced and simulated by Geant4 software.The result of the calibration with the collimated β source is in accord with the Geant4 simulations,which verifies the validity of this method. | ZOU Hong LUO Lin LI ChenFang JIA XiangHong XU Feng CHEN HongFei CHEN Jiang SHI WeiHong YU XiangQian ZOU JiQing | 2013 | Science China(Technological Sciences)2013，56，11： | 10 |
| 3 | Discovery of ~4.0 Ga detrital zircons in the Changdu Block,North Qiangtang,Tibetan Plateau显示文摘在 situ 锆石由 LA-ICP-MS 和 MC-ICP-MS 标明日期使用, 3981 的由岩屑形成的锆石 ??? 鮼铧?? ? 裦蒚铩 ????? 偃 ?? 鮼 ?? 郥趽 ????腘 吗?? | ShiPing He RongShe Li Chao Wang HongFei Zhang WenHua Ji PuSheng Yu PingYang Gu Chao Shi | 2011 | Chinese Science Bulletin2011，56，7： | 9 |
| 4 | Surveillance of Noise Exposure Level in the Manufacturing Industry—China,2020显示文摘Introduction:Occupational noise exposure is a widespread issue in the manufacturing industry in China.Since 2019,the National Surveillance System for Occupational Hazards in the workplace was established to understand different occupational hazards,especially occupational noise,in workplaces in China.Methods:Both environmental and individual noise exposure levels were measured for 19,378 enterprises according to the Work Plan for Surveillance of Occupational Hazards in the Workplace(2020)issued by National Health Commission of the People’s Republic of China.Median and interquartile range(IQR)were calculated to describe the distribution of the noise exposure level by industry classification,enterprise-scale,and ownership type of the enterprise.Results:Overall,25.14%of the individual noise exposure samples exceeded the Chinese national standard among the selected enterprises.The overall median of environmental noise exposure level was 82.8 dB(A)in selected enterprises,while the median of individual noise exposure level was 81.3 dB(A).The individual noise exposure level in the manufacture of metal products,manufacture of motor vehicles,minisized enterprises,collective enterprises and private enterprises was relatively high.Conclusion:Occupational noise is still one of the occupational hazards that cannot be ignored in the manufacturing industry,especially in mini-sized and private enterprises.The risk of noise exposure in the target industry is still high and will pose a threat to the health of workers. | Jinnan Zheng Siyu Zhang Hongfei Wang Yue Yu Weijiang Hu | 2021 | China CDC weekly2021，3，43： | 9 |
| 5 | Anti-proton contamination design of the imaging energetic electron spectrometer based on Geant4 simulation显示文摘The measurement of energetic particles plays an important role in the space environment monitoring and space weather forecasting.The accuracy of the energetic electron measurement is seriously influenced by the proton contamination.An anti-proton contamination design for the sensor of imaging energetic electron spectrometer is introduced in this paper.According to the electron and proton spectrum on the typical satellite orbits calculated by the radiation belt models,the efficiency of the anti-proton contamination design is estimated by the Geant4 simulation and the design is optimized based on the simulation results. | LUO Lin ZOU Hong ZONG QiuGang WANG LingHua CHEN HongFei SHI WeiHong YU XiangQian | 2015 | Science China(Technological Sciences)2015，58，8： | 7 |
| 6 | Resveratrol induces AMPK and mTOR signaling inhibition-mediated autophagy and apoptosis in multiple myeloma cells显示文摘Resveratrol,a natural compound extracted from the skins of grapes,berries,or other fruits,has been shown to have anti-tumor effects against multiple myeloma(MM)via promoting apoptosis and inhibiting cell viability.In addition to apoptosis,autophagy also plays a significant role in anti-tumor effects.However,whether autophagy is involved in anti-MM activity of resveratrol remains unclear.In this study,human MM cell lines U266,RPMI-8226,and NCI-H929 were treated with resveratrol.Cell Counting Kit-8 assay and colony formation assay were used to measure cell viability.Western blot analysis was used to detect apoptosis-and autophagy-associated proteins.3-Methyladenine(3-MA)was applied to inhibit autophagy.Results showed that resveratrol inhibited cell viability and colony formation via promoting apoptosis and autophagy in MM cell lines U266,RPMI-8226,and NCI-H929.Resveratrol promoted apoptosis-related proteins,Caspase-3 activating poly-ADP-ribose polymerase and Caspase-3 cleavage,and decreased the protein level of Survivin in a dose-dependent manner.Additionally,resveratrol upregulated the levels of LC3 and Beclin1 in a dose-dependent way,indicating that autophagy might be implicated in anti-MM effect of resveratrol.Furthermore,3-MA relieved the cytotoxicity of resveratrol by blocking the autophagic flux.Resveratrol increased the phosphorylation of adenosine monophosphate(AMP)-activated protein kinase and decreased the phosphorylation of mammalian target of rapamycin(mTOR)and its downstream substrates p70S6K and 4EBP1 in a dose-dependent manner,leading to autophagy.Therefore,our results suggest that resveratrol exerts anti-MM effects through apoptosis and autophagy,which can be used as a new therapeutic strategy for MM in clinic. | Ruye Ma Dandan Yu Yu Peng Hongfei Yi Yingcong Wang Taofang Cheng Bingqing Shi Guang Yang Weiming Lai Xiaosong Wu Ye Lu Jumei Shi | 2021 | Acta Biochimica et Biophysica Sinica2021，53，6： | 7 |
| 7 | Enhanced performance of GaN nanobelt-based photodetectors by means of piezotronic effects显示文摘轧紫外(紫外) 光电探测器(PD ) 在严厉环境由于他们的化学稳定性吸引了巨大的注意。尽管联系 Schottky 的基于陷阱的紫外 PD 比欧姆的接触的与更好的性能被实现了,在本地 Schottky 接触的障碍高度怎么控制传感器表演,仍然保持未知。在这个工作, piezotronic 效果被采用在本地接触调节 Schottky 障碍高度(SBH ) 并且因此提高组织的联系 Schottky 的 metal-semiconductor-metal (MSM ) 的表演轧了基于的 nanobelt (NB ) PD。一般来说,当在设备上使用紧张时, PD 的反应水平被 piezotronic 效果显然提高。PD 的 responsivity 被 18% 增加,并且敏感被提高由从 22% ~ 31% ,当与轻紧张从 12 ~ 2 W/cm2 由 325 nm 激光照亮了时。小心地用乐队结构图学习机制表明 PD 表演的观察改进从变化导致了外部紧张以及轻紧张引起的 SBH。使用 piezotronic 效果因此提供一个实际方法提高由做的 PD 的表演不仅轧,而且另外的 wurtzite 和锌闪锌矿家庭材料。 | Ruomeng Yu Caofeng Pan Youfan Hu Lin Li Hongfei Liu Wei Liu Soojin Chua Dongzhi Chi Zhong Lin Wang | 2013 | Nano Research2013，6，10： | 6 |
| 8 | Imaging energetic electron spectrometer onboard a Chinese navigation satellite in the inclined GEO orbit显示文摘The energetic electron measurement is one of the most important issues to understand dynamics in space physics and the applications for space weather. In this study, the principle and functional components of the imaging energetic electron spectrometer(IES) onboard a Chinese navigation satellite in the inclined GEO orbit(IGSO) was introduced. The IES instrument is developed by the team in Peking University(BeiDa), thus it is named as BD-IES. Based on the pin-hole technique, the instrument can measure 50–600 keV electrons incident from 9 directions over a range of 180° in polar angle. With pulse height analysis(PHA), the spectrum can be determined for each direction. The energy and angular calibrations were performed, which show the good energy and angular characteristics of BD-IES. Monte Carlo simulations show that the anti-proton design of BDIES can effectively decrease the proton contamination on the electron measurements in the inclined GEO orbit. The primary results of BD-IES verify the successful design of this instrument. | ZOU Hong YE YuGuang ZONG QiuGang CHEN HongFei ZOU JiQing CHEN Jiang SHI WeiHong YU XiangQian ZHONG WeiYing WANG YongFu ZHOU XuZhi HAO YiXin CHEN XingRan JIA XiangHong XU Feng SHAO SiPei WANG Bo HAO XiaoYun ZHANG XiaoXin | 2018 | Science China(Technological Sciences)2018，61，12： | 5 |
| 9 | Effects of Martian crustal magnetic field on its ionosphere显示文摘The effect of the Martian crustal magnetic field is one of the hot topics of the study of Martian ionosphere.The studies on this topic are summarized in this paper.Main data of the Martian ionosphere were resulted from radio occultation experiments.According to the observations,the electron density scale height and the peak electron density of the Martian ionosphere are influenced by its crustal magnetic field.The strong horizontal magnetic field prevents the vertical diffusion of the plasma and makes the electron density scale height in the topside ionosphere close to that in the photo equilibrium region.In the cusp-like regions with strong vertical magnetic field,the enhanced vertical diffusion leads to a larger electron density scale height in the diffusion equilibrium region.The observation of radio occultation experiment onboard Mars Global Surveyor (MGS) showed that the averaged peak electron density observed in the southern hemisphere with strong crustal magnetic field was slightly larger than that in the northern hemisphere with weak crustal magnetic field.The Mars advanced radar for subsurface and ionosphere sounding (MARSIS) onboard Mars Express (MEX) was the first topside sounder to be used to observe Martian ionosphere.The MARSIS results confirmed that the enhancement of the peak electron density occurred in cusp-like regions with open field lines,and the amount of the enhancement was much larger than that observed by the radio occultation experiment.There are two possible mechanisms for the peak electron density enhancement in the cusp-like crustal magnetic field regions:One is the precipitation of the energetic particles and the other is the heating by the waves excited by plasma instabilities.It's difficult to determine which one is the key mechanism for the peak electron density enhancement.Based on these studies,several interesting problems on the Martian ionosphere and plasma environment are presented. | ZOU Hong,CHEN HongFei,YU Ning,SHI WeiHong,YU XiangQian,ZOU JiQing & ZHONG WeiYing Institute of Space Physics and Applied Technology,Peking University,Beijing 100871,China | 2010 | Science China(Technological Sciences)2010，53，6： | 4 |
| 10 | Monte Carlo simulations of the sensor head of imaging energetic electron spectrometer onboard a Chinese IGSO navigation satellite显示文摘An imaging energetic electron spectrometer built by the Peking University team(BD-IES) onboard a Chinese navigation satellite in an inclined GEO orbit has been launched successfully in September 2015, which measures the spectra of the energetic electrons with the energy range of 50–600 keV in nine directions. In this study, Monte Carlo simulations of the BD-IES sensor head were performed using Geant4 and the corresponding characteristic responses to the isotropic energetic particles were derived. The effective geometric factors were estimated using the typical electron and proton spectra in the GEO orbit and the corresponding simulated sensor head responses. It was found that the average effective geometric factors of nine directions are close to the nominal geometric factors calculated with the traditional method, but the effective geometric factor decreases as the center energy of the energy channel decreases. The BD-IES sensor head also responses to the energetic protons, but the average contamination rate of all 72 channels is about 2%, which means that the proton contamination is acceptable. The spectra of the energetic electrons measured by BD-IES are derived using the effective geometric factors of the sensor head and are comparable with the spectra measured by the magnetic electron ion spectrometer(MagEIS) instrument onboard Van Allen Probes. | ZOU Hong YE YuGuang ZONG QiuGang CHEN HongFei LUO Lin ZHOU XuZhi CHEN XingRan HAO YiXin REN Jie WANG YongFu SHI WeiHong YU XiangQian JIA XiangHong XU Feng ZHANG XiaoXin | 2019 | Science China(Technological Sciences)2019，62，7： | 3 |
| 11 | The first pulsar discovered by FAST显示文摘To assist with the commissioning [1] of the Five-hundredmeter Aperture Spherical radio Telescope (FAST), we performed a pulsar search, with the primary goal of developing and testing the pulsar data acquisition and processing pipelines. We tested and used three pipelines, two (Pl and P2 hereafter) searched for the periodic signature of pulsars whereas the other one was used to search for bright single pulses (P3 hereafter). | Lei Qian ZhiChen Pan Di Li George Hobbs WeiWei Zhu Pei Wang ZhiJie Liu YouLing Yue Yan Zhu HongFei Liu DongJun Yu JingHai Sun Peng Jiang GaoFeng Pan Hui Li HengQian Gan Rui Yao XiaoYao Xie Fernando Camilo Andrew Cameron Lei Zhang Shen Wang FAST Collaboration | 2019 | Science China(Physics,Mechanics & Astronomy)2019，62，5： | 3 |
| 12 | An Identity-Based Proxy Signature on NTRU Lattice显示文摘Proxy signature plays an important role in distributed systems, mobile agent applications, distributed shared object systems, global distribution networks and mobile communications etc., since it allows the original signer to delegate another proxy signer to sign the message instead of himself. However, the proxy signature schemes constructed on the number theory cannot resist quantum computers attack and depend on the public key infrastructure. To mitigate these problems, the alternative schemes are Identity-based proxy signature constructed on lattice.In this paper, an identity-based proxy signature scheme based on Number theorem research unit(NTRU) lattice is proposed and proven secure in the random oracle. Compared with the other existing identity-based proxy signature schemes, the proposed scheme outperforms them in terms of original signer's signature size and signing key size and proxy signer's signing key size. | ZHU Hongfei TAN Yu'an YU Xiao XUE Yuan ZHANG Qikun ZHU Liehuang LI Yuanzhang | 2018 | Chinese Journal of Electronics2018，27，2： | 3 |
| 13 | Direct measurement of the linear energy transfer of ions in silicon for space application显示文摘The single event effect(SEE) is an important consideration in electronic devices used in space environments because it can lead to spacecraft anomalies and failures. The linear energy transfer(LET) of ions is commonly investigated in studies of SEE. The use of a thin detector is an economical way of directly measuring the LET in space. An LET telescope consists of a thin detector as the front detector(D1), along with a back detector that indicates whether D1 was penetrated. The particle radiation effect monitor(PREM) introduced in this paper is designed to categorize the LET into four bins of 0.2–0.4, 0.4–1.0, 1.0–2.0 and 2.0–20 Me V·cm^2/mg, and one integral bin of LET>20 Me V·cm^2/mg. After calibration with heavy ions and Geant4 analysis, the LET boundaries of the first four bins are determined to be 0.236, 0.479, 1.196, 2.254, and 17.551 Me V·cm^2/mg, whereas that of the integral bin is determined to be LET>14.790 Me V·cm^2/mg. The acceptances are calculated by Geant4 analysis as 0.452, 0.451, 0.476, 0.446, and 1.334, respectively. The LET accuracy is shown to depend on the thickness of D1; as D1 is made thinner, the accuracy of the measured values increases. | CHEN HongFei YU XiangQian SHAO SiPei SHI WeiHong CUI ZhanGuo XIANG HongWen HAO ZhiHua ZOU JiQing ZHONG WeiYing ZOU Hong | 2016 | Science China(Technological Sciences)2016，59，1： | 2 |
| 14 | Gut,metabolism and nutritional Support for COVID-19:Experiences from China显示文摘There is little research that focuses on the relationship between the gut,metabolism,nutritional support and COVID-19.As a group of Chinese physicians,nutritionists and scientists working on the frontline treating COVID-19 patients,we aim to integrate our experiences and the current clinical evidence to address this pressing issue in this article.Based on our clinical observations and available evidence,we recommend the following practice.Firstly,the Nutritional Risk Screening 2002 tool should be used routinely and periodically;for patients with a score≥3,oral nutritional supplements should be given immediately.Secondly,for patients receiving the antiviral agents lopinavir/ritonavir,gastrointestinal side effects should be monitored for and timely intervention provided.Thirdly,for feeding,the enteral route should be the first choice.In patients undergoing mechanical ventilation,establishing a jejunal route as early as possible can guarantee the feeding target being achieved if gastric dilatation occurs.Fourthly,we suggest a permissive underfeeding strategy for severe/critical patients admitted to the intensive care unit during the first week of admission,with the energy target no more than 20 kcal/kg/day(for those on mechanical ventilation,this target may be lowered to 10–15 kcal/kg/day)and the protein target around 1.0–1.2 g/kg/day.If the inflammatory condition is significantly alleviated,the energy target may be gradually increased to 25–30 kcal/kg/day and the protein target to 1.2–1.5 g/kg/day.Fifthly,supplemental parenteral nutrition should be used with caution.Lastly,omega-3 fatty acids may be used as immunoregulators,intravenous administration of omega-3 fatty emulsion(10 g/day)at an early stage may help to reduce the inflammatory reaction. | Ting Yuanand Wei Chen Hua Jiang Jian-Cheng Zhang Jun Zeng Lu Wang Yu Wang Charles Damien Lu Lei Deng Hongfei Deng Kai Wang Ming-Wei Sun Ping Zhou Ting Yuan Wei Chen | 2020 | Burns & Trauma2020，8，1： | 2 |
| 15 | An analysis of the correlation between the fluxes of high-energy electrons and low-middle-energy electrons in the magnetosphere显示文摘The variation of the flux of energetic electrons in the magnetosphere has been proven to be strongly related to the solar wind speed. Observations of GEO orbit show that the flux of low-energy electrons is not only modulated by the solar wind speed, but, if a time delay is added, is also positively correlated to the flux of high-energy electrons. This feature provides a possible method to forecast the flux of high-energy electrons in GEO orbit. In this study, the correlations of the fluxes between the high-energy electrons and low-middle-energy electrons obtained at different L values and in different orbits are investigated to develop the application of this feature. Based on the analysis of long–term data observed by NOAA POES and GOES, the correlations between the fluxes of high-energy electrons and low–middle–energy electrons are good enough at different L values and in different orbits in quiet time, but this correlation is strongly affected by CME–driven geomagnetic storms. | LI ChenFang ZOU Hong ZONG QiuGang JIA XiangHong CHEN HongFei SHI WeiHong YU XiangQian | 2016 | Science China(Technological Sciences)2016，59，7： | 2 |
| 16 | Xinjiangoxylon Gen.Nov.,a New Gymnosperm from the Latest Permian of China显示文摘Following the greatest known end-Permian mass extinction plants have low diversity.Lycopsids and conifers dominated on land.A new gymnosperm Xinjiangoxylon gen.nov.is proposed based on a woody stem specimen collected from the Upper Permian(latest,Changhsingian) Upper Guodikeng Formation of the Taoshuyuan section,Turpan,Xinjiang Uygur Autonomous Region,Northwest China.The decorticated stem is characterized by a complex pith,endarch primary xylem and a thick secondary xylem cylinder.Numerous petrified woods were found in the Changhsingian at this section.However,there are rare wood fossils in the Early Triassic.The abrupt decrease of fossil woods worldwide relates to the crisis at the end of the Permian.Xinjiangoxylon turpanense gen et.sp.nov.appears to represents one gymnosperm that existed in the latest Permian. | SHI Xiao YU Jianxin LI Hui CHI Hongfei ZHANG Wu | 2014 | Acta Geologica Sinica(English Edition)2014，88，5： | 2 |
| 17 | The metabolism of soluble carbohydrates related to chilling injury in peach fruit exposed to cold stress显示文摘 | Ke Wang Xingfeng Shao Yifu Gong Yong Zhu Hongfei Wang Xinglong Zhang Dandan Yu Fang Yu Ziyun Qiu Hao Lu | 2013 | Postharvest Biology and Technology2013，，： | 1 |
| 18 | A dual-sys- tem variable grain cooperative coevolutionary algorithm: sat- ellite-module layout design显示文摘 | TENG Hongfei CHEN Yu ZENG Wei | 2010 | IEEE Transactions on Evolu- tionary Computation2010，14，3： | 1 |
| 19 | A two- stage feature selection method for text categorization 显示文摘 | JIANA MENG HONGFEI LINB YUHAI YU | 2011 | Computers and Mathematics with Applications2011，62，： | 1 |
| 20 | A randomized, multi-central, controlled study of patients with hepatitis B e antigen-positive chronic hepatitis B treated by adefovir dipivoxil or adefovir dipivoxil plus bicyclol显示文摘 | Wen Xie Guangfeng Shi Hongfei Zhang Guiming Zhao Zujiang Yu Zhenwei Lang Hong Zhao Jie Yan Jun Cheng | 2012 | Hepatology International2012，，2： | 1 |
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