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| 1 | Differential diagnosis of left-sided abdominal pain:Primary epiploic appendagitis vs colonic diverticulitis显示文摘AIM:To investigate the clinical characteristics of left primary epiploic appendagitis and to compare them with those of left colonic diverticulitis.METHODS:We retrospectively reviewed the clinical records and radiologic images of the patients who presented with left-sided acute abdominal pain and had computer tomography(CT) performed at the time of presentation showing radiological signs of left primary epiploic appendagitis(PEA) or left acute colonic diverticulitis(ACD) between January 2001 and December 2011. A total of 53 consecutive patients were enrolled and evaluated. We also compared the clinical characteristics,laboratory findings,treatments,and clinical results of left PEA with those of left ACD.RESULTS:Twenty-eight patients and twenty-five patients were diagnosed with symptomatic left PEA and ACD,respectively. The patients with left PEA had focal abdominal tenderness on the left lower quadrant(82.1%). On CT examination,most(89.3%) of the patients with left PEA were found to have an oval fatty mass with a hyperattenuated ring sign. In cases of left ACD,the patients presented with a more diffuse abdominal tenderness throughout the left side(52.0%vs 14.3%; P = 0.003). The patients with left ACD had fever and rebound tenderness more often than those with left PEA(40.0% vs 7.1%,P = 0.004; 52.0% vs14.3%,P = 0.003,respectively). Laboratory abnormalities such as leukocytosis were also more frequently observed in left ACD(52.0% vs 15.4%,P = 0.006).CONCLUSION:If patients have left-sided localized abdominal pain without associated symptoms or laboratory abnormalities,clinicians should suspect the diagnosis of PEA and consider a CT scan. | Jeong Ah Hwang Sun Moon Kim Hyun Jung Song Yu Mi Lee Kyung Min Moon Chang Gi Moon Hoon Sup Koo Kyung Ho Song Yong Seok Kim Tae Hee Lee Kyu Chan Huh Young Woo Choi Young Woo Kang Woo Suk Chung | 2013 | World Journal of Gastroenterology2013，19，40： | 6 |
| 2 | Alterations of Gefitinib Pharmacokinetics by Co-administration of Herbal Medications in Rats显示文摘Objective: To evaluate the potential pharmacokinetic interactions of the anticancer agent gefitinib(Iressa?) and the oriental medications Guipi Decoction(归脾汤, GPD, Guibi-tang in Korean) and Bawu Decoction(八物汤, BWD, Palmul-tang in Korean). Methods: Methylcellulose(MC, control), GPD(1,200 mg/kg), or BWD(6,000 mg/kg) was orally administered to rats either as a single dose or multiple doses prior to gefitinib administration. To examine the effects of a single dose of the herbal medicines, gefitinib(10 mg/kg) was orally administered after 5 min or 1 h of MC or the herbal medicine pretreatments. To examine the effects of the multiple doses of the herbal medicines, gefitinib(10 mg/kg) was orally administered following 7 consecutive days of the administration of MC or each herbal medicine. The plasma concentrations of gefitinib were determined with liquid chromatography-tandem mass spectrometry assay. The plasma concentration-time profiles of gefitinib were analyzed with a noncompartmental analysis. Results: Gefitinib was rapidly absorbed and showed a monoexponential decline with an elimination half-life of 3.7–4.1 h. The pharmacokinetics of gefitinib was not affected by GPD pretreatment. However, a significantly lower maximum plasma concentration(Cmax, P<0.05) and area under the curve(P<0.05), and a delayed time to reach Cmax(Tmax, P<0.01) were observed in both single-and multipledose BWD-pretreated rats compared with the control rats. Conclusions: BWD and not GPD might delay and interfere with gefitinib absorption. Further evaluations of the clinical significance of these findings are needed. | Kwon-Yeon Weon Min Gi Kim Soyoung Shin Tae Hwan Kim Sang Hoon Joo Eunsook Ma Seok Won Jeong Sun Dong Yoo Yu Seok Youn Beom Soo Shin | 2018 | Chinese Journal of Integrative Medicine2018，24，6： | 2 |
| 3 | The C allele of synonymous SNP (rs1142636, Asnl70Asn) in SYN1 is a risk factor for the susceptibility of Korean female schizophrenia 显示文摘 | YU GI Kim SK Park HJ | 2012 | Synapse2012，66，11： | 1 |
| 4 | Surgical outcomes and complications associated with presurgical tyrosine kinase inhibition for advanced renal cell carcinoma (RCC)显示文摘 | Harshman LC Yu RJ Allen GI | 2013 | Urologic Oncology2013，，03： | 1 |
| 5 | Surgical outcomes and complications associated with presurgical tyrosine kinase inhibi- tion for advanced renal cell carcinoma (RCC) 显示文摘 | Harshman LC Yu R J Allen GI | 2013 | Urol Oncol2013，31，： | 1 |
| 6 | A polymorphism at-1607 2G in the matrix metalloproteinase-1 (MMP-1) increased risk of sudden deafness in Korean population but not at-519A/G in MMP-1显示文摘 | Nam SI Yu GI Kim HJ | | 0，，1： | 1 |
| 7 | Intracranial Ganglioglioma: Preoperative Characteristics and Oncologic Outcome after Surgery显示文摘 | So-Hyang Im Chun Kee Chung Byung-Kyu Cho Kyu-Chang Wang In-Kyu Yu In Chan Song Gi Jeong Cheon Dong Soo Lee Na-Rae Kim Je G. Chi | 2002 | Journal of Neuro - Oncology2002，，2： | 1 |
| 8 | Association of interleukila-10 promoter region polymorphisms with risk factors of Atherosclerosis 显示文摘 | Yu GI Jun SE Cho HC | 2015 | Int J Immunogenet2015，42，1： | 1 |
| 9 | Cryogenic reliability of the sandwich insulation board for LNG ship显示文摘 | Young Ho Yu Bu Gi Kim Dai Gil Lee | 2013 | Composite Structures2013，，： | 1 |
| 10 | Cryogenic reliability of composite insulation panels for liquefied natural gas (LNG) ships显示文摘 | Young Ho Yu Bu Gi Kim Dai Gil Lee | 2011 | Composite Structures2011，，2： | 1 |
| 11 | A polymorphism at -1607 2G in the matrix metalloproteinase-1 (MMP-1) increased risk of sudden deafness in Korean population but not at -519A/G in MMP- l显示文摘 | Nam SI Yu GI Kim HJ | 2011 | Laryngoscope2011，121，1： | 1 |
| 12 | Synthesis of conducting poly- aniline/TiO2 composite nano? bres by one-step in situ polymer ization method显示文摘 | Bian Chaoqing Yu Yijun Xue Gi | 2006 | Journal of Applied Polymer Science2006，，： | 1 |
| 13 | Association of promoter region single nucleotide polymorphisms at positions-819C/T and-592C/A of interleukin 10gene with ischemic heart disease显示文摘 | Yu GI Cho HC Cho YK | 2012 | Inflamm Ras2012，61，8： | 1 |
| 14 | Cryogenic reliability of composite insulation panels for liquefied natural gas(LNG)ships显示文摘 | Yu Young Ho Kim Bu Gi Lee Dai Gil | | 0，，： | 1 |
| 15 | A polymorphism at -1607 2G in the matrix metalloproteinase- 1 ( MMP- 1) increased risk of sudden deafness in korean population but not at - 519A/G in MMP- 1显示文摘 | Nam SI Yu GI Kim HJ | 2011 | Laryngoscope2011，121，： | 1 |
| 16 | Carbon nanotube/polyaniline core-shell nanowires prepared by in situ inverse microemulsion显示文摘 | Yijun Yu Bo Che Zhihua Si Liang Li Wei Chen Gi Xue | 2005 | Synthetic Metals2005，，3： | 1 |
| 17 | TNFalpha promoter polymorphism is a risk factor for susceptibility in hepat~ellular carcinoma in Korean population 显示文摘 | Jung KW Ha E Yu GI | 2009 | Clin Chim Acta2009，407，12： | 1 |
| 18 | A polymorphism at -1607 2G in the matrix metalloproteinase-1 (MMP-1) increased risk of sudden deafness in Korean population but not at - 519A/G in MMP-I显示文摘 | Nam SI Yu GI Kim HJ | 2011 | The Laryngoscope2011，121，1： | 1 |
| 19 | The dominant negative LQT2 mutation A561V reduces wild-type HERG expression 显示文摘 | Kagan A Yu Z Fishman GI | 2000 | J Biol Chem2000，275，11： | 1 |
| 20 | Association of promoter region single nu- cleotide polymorphisms at positions -819C/T and -592C/A of interleukin 10 gene with ischemic heart disease显示文摘 | Yu GI Cho HC Cho YK | 2012 | Inflamm Res2012，61，8： | 1 |
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