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10篇 您的检索式:作者名="Allen GI"
    题名 作者 年代 出处 被引量
1Fecal microbes, short chain fatty acids, and colorectal cancer across racial/ethnic groups显示文摘AIM:To investigate differences in microbes and short chain fatty acid(SCFA) levels in stool samples from Hispanic and non-Hispanic African American,American Indian,and White participants.METHODS:Stool samples from twenty participants were subjected to analysis for relative levels of viable bacteria and for SCFA levels.Additionally,the samples were subjected to 16 S r RNA gene pyrosequencing for identification of bacteria present in the stool.We used a metagenome functional prediction technique to analyze genome copy numbers and estimate the abundance of butyrate kinase in all samples.RESULTS:We found that African Americans had significantly lower levels of acetate,butyrate,and total SCFAs than all other racial/ethnic groups.We also found that participant microbial profiles differed by racial/ethnic group.African Americans had significantly more Firmicutes than Whites,with enriched Ruminococcaceae.The Firmicutes /Bacteroidetes ratio was also significantly higher for African Americans than for Whites(P =0.049).We found Clostridium levels to be significantly and inversely related to total SCFA levels(P =0.019) and we found Bacteroides to be positively associated(P =0.027) and Clostridium to be negatively associated(P =0.012) with levels of butyrate.We also identified a correlation between copy number for a butyrate kinase predicted from 16 S r RNA gene abundance and levels of butyrate in stool.CONCLUSION:The identified differences in gut flora and SCFA levels may relate to colorectal cancer mortality differentials and may be useful as targets for future clinical and behavioral interventions.Christina M Hester Venkatakrishna R Jala Morgan GI Langille Shahid Umar K Allen Greiner Bodduluri Haribabu 2015World Journal of Gastroenterology2015,21,9:2
2Purification and Characterization of Staphylococcin BacR 1,a Broad Spectrum Bacteriocin显示文摘Scott S Crupper Allen J Gies John J Landolo 1997Applied and Environmental Microbiology1997,11,:1
3Surgical outcomes and complications associated with presurgical tyrosine kinase inhibition for advanced renal cell carcinoma (RCC)显示文摘Harshman LC Yu RJ Allen GI 2013Urologic Oncology2013,,03:1
4Surface proteins from Helicobacter pylori exhibit ehemotactie activity for human leuko- eytes and are present in gastric mucosa 显示文摘Mai UE PerezPerez GI Allen JB 1992J Exp Med1992,175,2:1
5Anti pyrine as a dialyzable reference to correct differences in efficiency among and within sampling devices during in vivo microdialysis显示文摘Yokel RA Allen DD Bur gi D E 1992J Pha rmacol To xicol Met h1992,,:1
6Surgical outcomes and complications associated with presurgical tyrosine kinase inhibi- tion for advanced renal cell carcinoma (RCC) 显示文摘Harshman LC Yu R J Allen GI 2013Urol Oncol2013,31,:1
7Surface proteins from helicobacter pylori exhibit chemotactiv activity for human leukocytes and are present in gastric mucosa显示文摘Mai UE Perez-Perez GI Allen JB 1992J Exp Med1992,175,:1
8Cerebrocerehellar communication systems显示文摘Allen GI Tsukahara N 1974Physiol Rev1974,54,4:1
9Surface proteins from Helicobacter pylori exhibit chemotactic activity for human leukocytes and are present in gastric mucosa 显示文摘 Perez-Perez GI Allen JB 1992J Exp Med1992,175,:1
10On the reproducibility of TCGA ovarian cancer microRNA profiles显示文摘Wan YW Mach CM Allen GI 2014PLoS One2014,9,87:1
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