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| 1 | Methylation of RAR-β2, RASSF1A, and CDKN2A Genes Induced by Nickel Subsulfide and Nickel-carcinogenesis in Rats显示文摘Objective To investigate the expression variation of RAR‐β2, RASSF1A, and CDKN2A gene in the process of nickel‐induced carcinogenesis. Methods Nickel subsulfide (Ni 3 S 2 ) at dose of 10 mg was given to Wistar rats by intramuscular injection. The mRNA expression of the three genes in induced tumors and their lung metastasis were examined by Real‐time PCR. The methylation status of the 5' region of these genes were detected by Quantitative Real‐time methylation specific PCR. Results The mRNA expressions of the three genes both in muscle and lung tumor were decreased distinctly in comparison with normal tissue. But hypermethylation was found only in muscle tumor. Conclusion These findings suggest that loss of function or decrease of RAR‐β2, RASSF1A, and CDKN2A, as well as the hypermethylation of 5' region of these genes, are related with nickel exposure. | ZHANG Jun ZHANG Jing LI MengJie Wu YouJun FAN YingYing ZHOU Yang TAN LiLi SHAO ZhiHua SHI HongJun | 2011 | Biomedical and Environmental Sciences2011，24，2： | 4 |
| 2 | Elementary Experiences,Problems and Countermeasures of County Forestry Economy显示文摘County forestry economy is a strong power for regional green economic development,and an important way to improve farmers' income and promote living environment in urban and rural areas. According to the investigation of ten typical counties or cities with forestry industrial advantage,this paper sums up the elementary experiences of county forestry economy,analyzes its prominent problems. Countermeasures are brought forward to improve the development of county forestry economy. | Shaozhi CHEN Baomin FAN Rong ZHAO Youjun HE Decheng ZHANG | 2013 | Asian Agricultural Research2013，5，3： | 2 |
| 3 | In situ time-resolved FTIRS study of adsorption and oxidation of ethylene glycol on Pt(100) electrode显示文摘Adsorption and oxidation of ethylene glyco(EG) on Pt(100) electrode were studied by in situ timeresolved FTIRS (TRFTIRS). The TRFTIR spectra recordedat 0.10 V illustrate that an IR band appears near 2050 cm?at t > 5 s, corresponding to linearly bonded CO formed indissociative adsorption of EG. The TRFTIR results haveconfirmed also that CO species are distributed uniformly onPt(100) surface. Another band appears near 2342 cm?1 at > 70 s, associating with IR absorption of CO2 produced inthe direct oxidation of EG. With the increase of electrodepotential, the direct oxidation of EG becomes gradually themain reaction. When the potential is above 0.40 V, the oxidation of EG occurs mainly via the reactive intermediates, i.especies containing –COOH determined by in situ TRFTIRS. | FAN Youjun ZHOU Zhiyou FAN Chunjie ZHEN Chunhua CHEN Shengpei SUN Shigang | 2005 | Chinese Science Bulletin2005，50，18： | 2 |
| 4 | Studies of surface processes of electrocatalytic reduction of CO_2 on Pt(210), Pt(310) and Pt(510)显示文摘Surface processes of CO2 reduction on Pt(210), Pt(310), and Pt(510) electrodes were studied by cyclic voltammetry. Different surface structures of these platinum single crystal electrodes were obtained by various treatment conditions. The experimental results illustrated that the electrocatalytic activity of Pt single crystal electrodes towards CO2 reduction is decreased in an order of Pt(210)>Pt(310)>Pt(510), i.e., with the decrease of (110) step density on well-defined surfaces. When the surfaces were reconstructed due to oxygen adsorption, the catalytic activity of all the three electrodes has been enhanced to a cer- tain extent. Although the activity order remains unchanged, the electrocatalytic activity has been en- hanced more significantly as the density of (110) step sites is more intensive on the Pt single crystal surface. It has revealed that the more open the surface structure is, the more active the Pt single crystal electrode will be, and the easier for the electrode to be transformed into a surface structure that exhib- its higher activity under external inductions. However, the relatively ordered surfaces of Pt single crystal electrode are comparatively stable under the same external inductions. The present study has gained knowledge on the interaction between CO2 and Pt single crystal electrode surfaces at a micro- scopic level, and thrown new insight into understanding the surface processes of electrocatalytic re- duction of CO2. | FAN ChunJie FAN YouJun ZHEN ChunHua ZHENG QingWei SUN ShiGang | 2007 | Science China Chemistry2007，50，5： | 1 |
| 5 | Ultra-robust stretchable electrode for e-skin:In situ assembly using a nanofiber scaffold and liquid metal to mimic water-to-net interaction显示文摘The development of stretchable electronics could enhance novel interface structures to solve the stretchability-conductivity dilemma,which remains a major challenge.Herein,we report a nano-liquid metal(LM)-based highly robust stretchable electrode(NHSE)with a self-adaptable interface that mimics water-tonet interaction.Based on the in situ assembly of electrospun elastic nanofiber scaffolds and electrosprayed LM nanoparticles,the NHSE exhibits an extremely low sheet resistance of 52 mΩsq^(-1).It is not only insensitive to a large degree of mechanical stretching(i.e.,350%electrical resistance change upon 570%elongation)but also immune to cyclic deformation(i.e.,5%electrical resistance increases after 330000 stretching cycles with 100%elongation).These key properties are far superior to those of the state-of-the-art reports.Its robustness and stability are verified under diverse circumstances,including long-term exposure to air(420 days),cyclic submersion(30000 times),and resilience against mechanical damages.The combination of conductivity,stretchability,and durability makes the NHSE a promising conductor/electrode solution for flexible/stretchable electronics for applications such as wearable on-body physiological signal detection,human-machine interaction,and heating e-skin. | Jinwei Cao Fei Liang Huayang Li Xin Li Youjun Fan Chao Hu Jing Yu Jin Xu Yiming Yin Fali Li Dan Xu Hanfang Feng Huali Yang Yiwei Liu Xiaodong Chen Guang Zhu Run-Wei Li | 2022 | InfoMat2022，4，4： | 1 |
| 6 | Multilayered flexible nanocomposite for hybrid nano- generator enabled by conjunction of piezoelectricity and triboelectricity显示文摘我们制作灵活混合 nanogenerator (HNG ) ,基于 multilayered nanocomposite 材料,它与仅仅二个电极把压电的 nanogenerator (PENG ) 和摩擦电 nanogenerator (TENG ) 集成到单个结构。HNG 启用 nanogenerators 的电的产量的改进。 280 V 的开电路的电压和 25 A 的电线走火电流被 2.5 厘米的 HNG 完成?????匠?洠捩潲楰汬牡??洠捩潲档湡敮????????????????洠捩潲渭湡???????????吗 洠捩潲汦極楤 ?? | Huayang Li Li Su Shuangyang Kuang Youjun Fan Ying Wu Zhong Lin Wang Guang Zhu | 2017 | Nano Research2017，10，3： | 1 |
| 7 | Stretchable polymer composites with ultrahigh piezoelectric performance显示文摘Flexible piezoelectric materials capable of withstanding large deformation play key roles in flexible electronics.Ferroelectric ceramics with a high piezoelectric coefficient are inherently brittle,whereas polar polymers exhibit a low piezoelectric coefficient.Here we report a highly stretchable/compressible piezoelectric composite composed of ferroelectric ceramic skeleton,elastomer matrix and relaxor ferroelectric-based hybrid at the ceramic/matrix interface as dielectric transition layers,exhibiting a giant piezoelectric coefficient of 250 picometers per volt,high electromechanical coupling factor keff of 65%,ultralow acoustic impedance of 3MRyl and high cyclic stability under 50%compression strain.The superior flexibility and piezoelectric properties are attributed to the electric polarization and mechanical load transfer paths formed by the ceramic skeleton,and dielectric mismatch mitigation between ceramic fillers and elastomer matrix by the dielectric transition layer.The synergistic fusion of ultrahigh piezoelectric properties and superior flexibility in these polymer composites is expected to drive emerging applications in flexible smart electronics. | Tongxiang Tang Zhonghui Shen Jian Wang Shiqi Xu Jiaxi Jiang Jiahui Chang Mengfan Guo Youjun Fan Yao Xiao Zhihao Dong Houbing Huang Xiaoyan Li Yihui Zhang Danyang Wang Long-Qing Chen Ke Wang Shujun Zhang Ce-Wen Nan Yang Shen | 2023 | National Science Review2023，10，8： | 1 |
| 8 | A shape-persistent plasticine-like conductive hydrogel with self-healing properties for peripheral nerve regeneration显示文摘In recent years,electrically conductive hydrogel-based nerve guidance conduits(NGCs)have yielded promising results for treating peripheral nerve injuries(PNIs).However,developed ones are generally pre-manufactured and exhibit a limited ability to achieve good contact with nerve tissue with irregu-lar surfaces.Herein,we developed a plasticine-like electrically conductive hydrogel consisting of gelatin,conducting polypyrrole,and tannic acid(named GPT)and assessed its ability to promote peripheral nerve regeneration.The shape-persistent GPT hydrogel exhibited good self-healing properties and could easily be molded to form a conduit that could match any injured nerve tissue.Their electrical properties could be tuned by changing the PPy concentration.In vitro,the improved conductivity of the hydrogel pro-moted dorsal root ganglion(DRG)axonal extension.More importantly,we found that the GPT hydrogel enhanced axonal regeneration and remyelination in vivo,preventing denervation atrophy and enhancing functional recovery in a mice model of sciatic nerve injury.These results suggest that our plasticine-like NGC has huge prospects for clinical application in the repair of PNI. | Xinchang Kang Xiaojun Li Can Liu Min Cai Pengfei Guan Yian Luo Youjun Guan Yu Tian Kunyu Ren Chengyun Ning Lei Fan Guoxin Tan Lei Zhou | 2023 | Journal of Materials Science & Technology2023，，11： | 0 |
| 9 | Research on ECG classification based on transfer learning显示文摘Concerning current deep learning-based electrocardiograph(ECG) classification methods, there exists domain discrepancy between the data distributions of the training set and the test set in the inter-patient paradigm. To reduce the negative effect of domain discrepancy on the classification accuracy of ECG signals, this paper incorporates transfer learning into the ECG classification, which aims at applying the knowledge learned from the training set to the test set. Specifically, this paper first develops a deep domain adaptation network(DAN) for ECG classification based on the convolutional neural network(CNN). Then, the network is pre-trained with training set data obtained from the famous Massachusetts Institute of Technology-Beth Israel Hospital(MIT-BIH) ECG arrhythmia database. On this basis, by minimizing the multi-kernel maximum mean discrepancy(MK-MMD) between the data distributions of the training set and the test set, the pre-trained network is adjusted to learn transferable feature representations. Finally, with the low-density separation of unlabeled target data, the feature representations are more transferable. The extensive experimental results show that the proposed domain adaptation method has reached a 7.58% improvement in overall classification accuracy on the test set, and achieves competitive performance with other state-of-the-arts. | Jiang Fan Chen Jiajun Gao Youjun Sun Changyin | 2022 | The Journal of China Universities of Posts and Telecommunications2022，29，6： | 0 |
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