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		题名	作者	年代	出处	被引量
	1	Aspartate aminotransferase-immunoglobulin complexes in patients with chronic liver disease显示文摘AIM: To determine the complex of AST and immunoglobulin and to investigate its clinical significance in patients with liver disease.METHODS: The complex of AST and immunoglobulin was determined by encounter immunoelectrophoresis and its clinical significance was investigated in 128 patients with liver disease.RESULTS: AST was bound to immunoglobulin of antiimmunoglobulin A (IgA) class, but any binding to antiimmunoglobulin G and anti-immunoglobulin M classes was not observed. Although the incidence of ASTimmunoglobulin complex was 41.8% in chronic hepatitis (CH), the incidences in liver cirrhosis and hepatocellular carcinoma were 62.2 and 90.0%, respectively. In alcoholic liver disease with high level of serum IgA, the incidence of the complex was 66.7%, which was higher than that in CH. The ratio of binding to lambda-chain of IgA was higher than that to kappa-chain of IgA. The serum level of IgA and the ratio of AST/alanine aminotransferase (ALT) were significantly higher in patients with AST-IgA complex than in those without complex.CONCLUSION: These results suggest that AST-IgA complex in patients with progressive liver diseases and alcoholic liver injury can lead to elevation of the ratio of AST/ALT.	Masahiko Tameda Katsuya Shiraki Kinue Ooi Koujirou Takase Yoshitane Kosaka Tsutomu Nobori Yukihiko Tameda	2005	World Journal of Gastroenterology2005，11，10：	2
	2	Prolonged Endoplasmic Reticulum Stress in Hypertrophic and Failing Heart After Aortic Constriction: Possible Contribution of Endoplasmic Reticulum Stress to Cardiac Myocyte Apoptosis显示文摘	Ken-ichiro Okada Tetsuo Minamino Yoshitane Tsukamoto Yulin Liao Osamu Tsukamoto Seiji Takashima Akio Hirata Masashi Fujita Yoko Nagamachi Takeshi Nakatani Chikao Yutani Kentaro Ozawa Satoshi Ogawa Hitonobu Tomoike Masatsugu Hori Masafumi Kitakaze	2004	Circulation2004，，6：	2
	3	Adrenomedullin Infusion Attenuates Myocardial Ischemia/Reperfusion Injury Through the Phosphatidylinositol 3-Kinase/Akt-Dependent Pathway显示文摘	Hiroyuki Okumura Noritoshi Nagaya Takefumi Itoh Ichiro Okano Jun Hino Kenji Mori Yoshitane Tsukamoto Hatsue Ishibashi-Ueda Senri Miwa Keiichi Tambara Shinya Toyokuni Chikao Yutani Kenji Kangawa	2004	Circulation: Journal of the American Heart Association2004，，2：	1
	4	Characterization of the Human NDRG Gene Family: A Newly Identified Member, NDRG4, Is Specifically Expressed in Brain and Heart显示文摘	Rui-Hai Zhou Koichi Kokame Yoshitane Tsukamoto Chikao Yutani Hisao Kato Toshiyuki Miyata	2001	Genomics2001，，1：	1
	5	pH-responsive micellization of amine-containing cationic diblock copolymers prepared by reversible addition-fragmentation chain transfer (RAFT) radical polymerization显示文摘	Shin-Ichi Konishi Yoshitane	2005	Polymer Journal2005，37，7：	1
	6	Analysis of serum cytokine Levels in primary biliary cirrhosis patients and healthy adults显示文摘	Masayoshi YA Yoshitane KO Akira NI	1998	Clin Lab A nalysis1998，12，：	1

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