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| 1 | 郯庐断裂带形成演化的年代学研究显示文摘通过对郯庐断裂带东侧张八岭蓝片岩带内白云母4 0 Ar - 3 9Ar年龄、断裂带内片麻状花岗岩中钾长石4 0 Ar- 3 9Ar年龄以及断裂带内断层泥K -Ar、ESR年龄的测定 ,并结合有关的地质和古地磁资料 ,厘定了郯庐断裂带形成和演化的过程 :(1)三叠纪 (2 44~ 2 0 9Ma)由于华北与扬子地块碰撞 ,郯庐断裂带形成为其主要左行平移时期 ;(2 )侏罗纪 (189~ 16 4Ma)时郯庐断裂东侧下扬子地块可能经历了逆时针转动 ;(3)白垩纪 (10 3~ 94Ma)开始郯庐断裂带伴随走滑平移而发生正断活动 ;(4)晚白垩—第三纪右旋平移阶段。郯庐断裂的形成与大别 -苏鲁变质带有关。 | 陈宣华 王小凤 张青 陈柏林 陈正乐 Harrison TMark YinAn | 2000 | 长春科技大学学报2000，30，3： | 67 |
| 2 | Tri-Co Robot: a Chinese robotic research initiative for enhanced robot interaction capabilities显示文摘Since the invention of the first industrial robot in 1959, the missions of robots have evolved from basic mechanical transfer or assistance to a diverse range of tasks through close interactions with environment, their human counterparts and robot peers. Through adaptation to uncertain and dynamic environments. | Han Ding Xuejun Yang Nanning Zheng Ming Li Yinan Lai Hao Wu | 2018 | National Science Review2018，5，6： | 24 |
| 3 | Tomato SlAN11 regulates flavonoid biosynthesis and seed dormancy by interaction with bHLH proteins but not with MYB proteins显示文摘The flavonoid compounds are important secondary metabolites with versatile human nutritive benefits and fulfill a multitude of functions during plant growth and development.The abundance of different flavonoid compounds are finely tuned with species-specific pattern by a ternary MBW complex,which consists of a MYB,a bHLH,and a WD40 protein,but the essential role of SlAN11,which is a WD40 protein,is not fully understood in tomato until now.In this study,a tomato WD40 protein named as SlAN11 was characterized as an effective transcription regulator to promote plant anthocyanin and seed proanthocyanidin(PA)contents,with late flavonoid biosynthetic genes activated in 35S::SlAN11 transgenic lines,while the dihydroflavonol flow to the accumulation of flavonols or their glycosylated derivatives was reduced by repressing the expression of SlFLS in this SlAN11-overexpressed lines.The above changes were reversed in 35S::SlAN11-RNAi transgenic lines except remained levels of flavonol compounds and SlFLS expression.Interestingly,our data revealed that SlAN11 gene could affect seed dormancy by regulating the expressions of abscisic acid(ABA)signaling-related genes SlABI3 and SlABI5,and the sensitivity to ABA treatment in seed germination is conversely changed by SlAN11-overexpressed or-downregulated lines.Yeast two-hybrid assays demonstrated that SlAN11 interacted with bHLH but not with MYB proteins in the ternary MBW complex,whereas bHLH interacted with MYB in tomato.Our results indicated that low level of anthocyanins in tomato fruits,with low expression of bHLH(SlTT8)and MYB(SlANT1 and SlAN2)genes,remain unchanged upon modification of SlAN11 gene alone in the transgenic lines.These results suggest that the tomato WD40 protein SlAN11,coordinating with bHLH and MYB proteins,plays a crucial role in the fine adjustment of the flavonoid biosynthesis and seed dormancy in tomato. | Yongfeng Gao Jikai Liu Yongfu Chen Hai Tang Yang Wang Yongmei He Yongbin Ou Xiaochun Sun Songhu Wang Yinan Yao | 2018 | Horticulture Research2018，5，1： | 13 |
| 4 | Construction and external validation of a nomogram that predicts lymph node metastasis in early gastric cancer patients using preoperative parameters显示文摘Objective: To create a nomogram to predict the incidence of lymph node metastasis(LNM) in early gastric cancer(EGC) patients and to externally validate the nomogram.Methods: To construct the nomogram,we retrospectively analyzed a primary cohort of 272 EGC patients.Univariate analysis and a binary logistic regression were performed.A nomogram predicting the incidence of LNM in EGC patients was created.The discrimination ability of the nomogram was measured using the concordance index(c-index),and the nomogram was also calibrated.Then,another prospective cohort of 81 patients was analyzed to validate the nomogram.Results: In the primary cohort,LNM was pathologically confirmed in 37(13.6%) patients.In multivariate analysis,the presence of an ulcer,the maximum lesion diameter observed via gastroscopy,the thickness of the lesion observed via endoscopic ultrasonography,and the presence of enlarged lymph nodes on computed tomography(CT) were independent risk factors for LNM.A nomogram was then created based on the regression model with the c-index of 0.905,and the calibration curve of the nomogram fell approximately on the ideal 45-degree line.The cut-off score of the nomogram was 110,and the sensitivity,specificity,positive predictive and negative predictive values of the nomogram in the primary cohort were 81.1%,86.0%,47.6% and 96.7%,respectively,and in the prospective validation cohort were 75.0%,91.0%,60.0% and 95.5%,respectively.The calibration curve of the external validation cohort was almost on the 45-degree line.Conclusions: We developed an effective nomogram predicting the incidence of LNM for EGC patients. | Yinan Zhang Yiqiang Liu Ji Zhang Xiaojiang Wu Xin Ji Tao Fu Ziyu Li Qi Wu Zhaode Bu Jiafu Ji | 2018 | Chinese Journal of Cancer Research2018，30，6： | 12 |
| 5 | Discrete Variable Structural Optimization based on Multidirectional Fuzzy Genetic Algorithm显示文摘Round method is the common method for discrete variable optimization in optimal design of complex mechanical structures;however,it has some disadvantages such as poor precision,simple model and lacking of working conditions' description,etc.To solve these problems,a new model is constructed by defining parameterized fuzzy entropy,and the rationality of parameterized fuzzy entropy is verified.And a new multidirectional searching algorithm is further put forward,which takes information of actual working conditions into consideration and has a powerful local searching capability.Then this new algorithm is combined with the GA by the fuzzy clustering algorithm(FCA).With the application of FCA,the optimal solution can be effectively filtered so as to retain the diversity and the elite of the optimal solution,and avoid the structural re-analysis phenomenon between the two algorithms.The structure design of a high pressure bypass-valve body is used as an example to make a structural optimization by the proposed HGA and finite element method(FEM),respectively.The comparison result shows that the improved HGA fully considers the characteristic of discrete variable and information of working conditions,and is more suitable to the optimal problems with complex working conditions.Meanwhile,the research provides a new approach for discrete variable structure optimization problems. | LAI Yinan DAI Ye BAI Xue CHEN Dongyan | 2012 | Chinese Journal of Mechanical Engineering2012，25，2： | 12 |
| 6 | Exceeding the limit of plasmonic light trapping in textured screen-printed solar cells using Al nanoparticles and wrinkle-like graphene sheets显示文摘The solar cell market is predominantly based on textured screen-printed solar cells.Due to parasitic absorption in nanostructures,using plasmonic processes to obtain an enhancement that exceeds 2.5%of the short-circuit photocurrent density is challenging.In this paper,a 7.2%enhancement in the photocurrent density can be achieved through the integration of plasmonic Al nanoparticles and wrinkle-like graphene sheets.For the first time,we experimentally achieve Al nanoparticle-enhanced solar cells.An innovative thermal evaporation method is proposed to fabricate low-coverage Al nanoparticle arrays on solar cells.Due to the ultraviolet(UV)plasmon resonance of Al nanoparticles,the performance enhancement of the solar cells is significantly greater than that from Ag nanoparticles.Subsequently,we deposit wrinkle-like graphene sheets over the Al nanoparticle-enhanced solar cells.Compared with planar graphene sheets,the bend carbon layer also exhibits a broadband light-trapping effect.Our results exceed the limit of plasmonic light trapping in textured screen-printed silicon solar cells. | Xi Chen Baohua Jia Yinan Zhang Min Gu | 2013 | Light(Science & Applications)2013，2，1： | 9 |
| 7 | Hepatic spheroids derived from human induced pluripotent stem cells in bio-artificial liver rescue porcine acute liver failure显示文摘Dear Editor,Acute liver failure(ALF)is a complicated disorder showing a nearly 80%mortality rate,and there is currently no effective medical solutions for ALF except liver transplantation.1 Bio-artificial liver(BAL)system is a device that consists of a bioreactor filled with hepatocytes,which could potentially rescue ALF patients by providing partial liver function until a suitable donor liver can be found or the native liver has self-regenerated. | Sitong Chen Jinglin Wang Haozhen Ren Yinan Liu Chengang Xiang Cheng Li Shichun Lu Yan Shi Hongkui Deng Xiaolei Shi | 2020 | Cell Research2020，30，1： | 9 |
| 8 | Review of micromachined optical accelerometers:from mg to sub-μg显示文摘Micro-Opto-Electro-Mechanical Systems(MOEMS)accelerometer is a new type of accelerometer which combines the merits of optical measurement and Micro-Electro-Mechanical Systems(MEMS)to enable high precision,small volume and anti-electromagnetic disturbance measurement of acceleration.In recent years,with the in-depth research and development of MOEMS accelerometers,the community is flourishing with the possible applications in seismic monitoring,inertial navigation,aerospace and other industrial and military fields.There have been a variety of schemes of MOEMS accelerometers,whereas the performances differ greatly due to different measurement principles and corresponding application requirements.This paper aims to address the pressing issue of the current lack of systematic review of MOEMS accelerometers.According to the optical measurement principle,we divide the MOEMS accelerometers into three categories:the geometric optics based,the wave optics based,and the new optomechanical accelerometers.Regarding the most widely studied category,the wave optics based accelerometers are further divided into four sub-categories,which is based on grating interferometric cavity,Fiber Bragg Grating(FBG),Fabry-Perot cavity,and photonic crystal,respectively.Following a brief introduction to the measurement principles,the typical performances,advantages and disadvantages as well as the potential application scenarios of all kinds of MOEMS accelerometers are discussed on the basis of typical demonstrations.This paper also presents the status and development tendency of MOEMS accelerometers to meet the ever-increasing demand for high-precision acceleration measurement. | Qianbo Lu Yinan Wang Xiaoxu Wang Yuan Yao Xuewen Wang Wei Huang | 2021 | Opto-Electronic Advances2021，4，3： | 8 |
| 9 | Atmospheric Profiling Synthetic Observation System in Tibet显示文摘1.Introduction The Atmosphere Profiling Synthetic Observation System(APSOS)is the first ground-based facility for profiling atmospheric variables and multiple constituents in the whole(neutral)atmosphere from the surface up to the lower thermosphere.It enables simultaneous observations and extensive studies of the atmospheric vertical structure and | Daren LU Weilin PAN Yinan WANG | 2018 | Advances in Atmospheric Sciences2018，35，3： | 8 |
| 10 | An Epidemic of Hepatitis A--Liaoning Province,2020显示文摘What is already known about this topic?Hepatitis A(HA)is caused by acute hepatitis A virus(HAV)infection and was once very common in China.Following the 2008 introduction of the HA vaccine into the national Expanded Program on Immunization(EPI),the incidence of reported HA in China decreased markedly.However,HA epidemics still occur in Liaoning Province every 3–5 years,although with far fewer cases than in the pre-HA-vaccination era.What is added by this report?Between January 1,2020 and March 18,2020,the number of reported cases of HA in Dalian and Dandong cities of Liaoning Province increased significantly compared with the same period in previous years.All cases were sporadic,and cases were seen in nearly every township.The increase in HA occurred one month after local fresh seafood became available with most cases being among adults.A casecontrol study showed that consuming raw or undercooked seafood,clams,snapping shrimp,and oysters were significantly associated with the increase in HA.What are the implications for public health practices?Strengthening health education for residents to avoid consumption of raw seafood and encouraging HAV vaccination of adults aged 20 to 54 years are important to prevent periodic HAV endemic outbreaks.Further multisectoral cooperation must be emphasized on HA surveillance in areas with a high prevalence of HA. | Jing Sun Yuanqiu Li Xing Fang Yan Wang Yinan Han Yang Liu Jingyuan Cao Wenting Zhou Hui Zheng Wenqing Yao | 2020 | China CDC weekly2020，2，30： | 7 |
| 11 | Brassica rapa Genome 2.0: A Reference Upgrade through Sequence Re-assembly and Gene Re-annotation显示文摘 | Chengcheng Cai Xiaobo Wang Bo Liu Jian Wu Jianli Liang Yinan Cui Feng Cheng Xiaowu Wang | 2017 | Molecular Plant2017，10，4： | 6 |
| 12 | Effect of low-level laser therapy on tooth-related pain and somatosensory function evoked by orthodontic treatment显示文摘Low-level laser therapy(LLLT) may have an effect on the pain associated with orthodontic treatment. The aim of this study was to evaluate the effect of LLLT on pain and somatosensory sensitization induced by orthodontic treatment. Forty individuals(12–33 years old; mean ± standard deviations: 20.8 ± 5.9 years) scheduled to receive orthodontic treatment were randomly divided into a laser group(LG) or a placebo group(PG)(1:1). The LG received LLLT(810-nm gallium-aluminium-arsenic diode laser in continuous mode with the power set at 400 mW, 2 J·cm–2) at 0 h, 2 h, 24 h, 4 d, and 7 d after treatment, and the PG received inactive treatment at the same time points. In both groups, the non-treated side served as a control. A numerical rating scale(NRS) of pain, pressure pain thresholds(PPTs), cold detection thresholds(CDTs), warmth detection thresholds(WDTs), cold pain thresholds(CPTs), and heat pain thresholds(HPTs) were tested on both sides at the gingiva and canine tooth and on the hand. The data were analysed by a repeated measures analysis of variance(ANOVA). The NRS pain scores were significantly lower in the LG group(P = 0.01). The CDTs,CPTs, WDTs, HPTs, and PPTs at the gingiva and the PPTs at the canine tooth were significantly less sensitive on the treatment side of the LG compared with that of the PG(P < 0.033). The parameters tested also showed significantly less sensitivity on the nontreatment side of the LG compared to that of the PG(P < 0.043). There were no differences between the groups for any quantitative sensory testing(QST) measures of the hand. The application of LLLT appears to reduce the pain and sensitivity of the tooth and gingiva associated with orthodontic treatment and may have contralateral effects within the trigeminal system but no generalized QST effects. Thus, the present study indicated a significant analgesia effect of LLLT application during orthodontic treatment.Further clinical applications are suggested. | Song Wu Yinan Chen Jinglu Zhang Wenjing Chen Sheng Shao Huijie Shen Ling Zhu Ping Ye Peter Svensson Kelun Wang | 2018 | International Journal of Oral Science2018，10，3： | 6 |
| 13 | Distinct regulatory mechanism of immunoglobulin gene transcription in epithelial cancer cells显示文摘The restriction of immunoglobulin(Ig)expression to B lymphocytes is well established.However,several reports have confirmed that the Ig gene can be expressed in many non-B cancer cells and/or some normal cells.Our aim is to determine whether the Ig gene promoter can be activated in non-B cancer cells and to identify the regulatory mechanism for Ig gene expression.Our results show that the Ig promoter of VH4-59 was activated in several non-B cancer cell lines.Moreover,two novel positive regulatory elements,an enhancer-like element at 2800 to 2610 bp and a copromoter-like element at 2610 to 2300 bp,were identified in two epithelial cancer cell lines,HeLa S3 and HT-29.The octamer element(59-ATGCAAAT-39)located in the Ig promoter,a crucial element for B-cell-derived Ig gene transcription,was also very important for non-B-cell-derived Ig gene transcription.More importantly,we confirmed that octamer-related protein-1(Oct-1),but not Oct-2,was a crucial transcriptional factor for Ig gene transcription due to its ability to bind to the octamer element of the Ig promoter in epithelial cancer cells.These results suggested the presence of a distinct regulatory mechanism for Ig gene expression in non-B cancer cells. | Xiaohui Zhu Lina Wu Li Zhang Peng Hao Shuai Zhang Jing Huang Jie Zheng Yinan Liu Wenjun Li Yingmei Zhang Chunyan Zhou Youhui Zhang C Cameron Yin Xiaoyan Qiu | 2010 | Cellular & Molecular Immunology2010，7，4： | 5 |
| 14 | Glycosylation of dentin matrix protein 1 is a novel key element for astrocyte maturation and BBB integrity显示文摘血大脑障碍(BBB ) 是在 endothelial 房间和星形细胞之间形成的一条紧密的边界,它在循环把大脑与大多数病原体以及神经毒素分开并且保护。然而,详细说明了涉及 BBB 的形成的分子的播放器完全不被知道。牙质矩阵蛋白质 1 (DMP1 )-proteoglycan (PG ) 被知道涉及骨头和牙质的矿化作用,也与未知功能包括大脑在软纸巾被表示。在现在的学习,我们报导 DMP1-PG 在大脑星形细胞被表示并且在 BBB 充实单位。DMP1 的唯一的 glycosylation 地点在在鼠标的蛋白质的 N 终端域是 serine89 (S89 ) 。有 DMP1 的变异的老鼠削尖把 S89 改变到 glycine (S89G ) 的变化,它蛋白质的完全根除的 glycosylation,表明的严重 BBB 混乱。DMP1 变异的鼠标的另一个品种,缺乏 DMP1 的 C 终端域,表明了正常 BBB 功能。S89G-DMP1 星形细胞的极性被破坏,房间房间粘附被松开。通过一组分析,我们发现 DMP1 glycosylation 极其在 vitro 并且在 vivo 为星形细胞成熟被要求。S89G-DMP1 变异的星形细胞没能表示 aquaporin 4 并且减少了 laminin 和 ZO1 表示,它导致了 BBB 的混乱。有趣地,在 nestin 倡导者驾驶的老鼠大脑的野类型的 DMP1-PG 的 overexpression 在野类型层次以外提高了 laminin 和 ZO1 表示并且能有效地抵抗的静脉内的导致甘露糖醇的 BBB 可逆的洞。一起拿,我们的学习不仅揭示了一个新奇元素,即, DMP1-PG,调整了 BBB 形成,而且把新功能分到 DMP1-PG。 | Bo Jing Chunxue Zhang Xianjun Liu Liqiang Zhou Jiping Liu Yinan Yao Juehua Yu Yuteng Weng Min Pan Jie Liu Zuolin Wang Yao Sun Yi Eve Sun | 2018 | Protein & Cell2018，9，3： | 5 |
| 15 | Band structure engineering in metal halide perovskite nanostructures for optoelectronic applications显示文摘Metal halide perovskite nanostructures have emerged as low-dimensional semiconductors of great significance in many fields such as photovoltaics,photonics,and optoelectronics.Extensive efforts on the controlled synthesis of perovskite nanostructures have been made towards potential device applications.The engineering of their band structures holds great promise in the rational tuning of the electronic and optical properties of perovskite nanostructures,which is one of the keys to achieving efficient and multifunctional optoelectronic devices.In this article,we summarize recent advances in band structure engineering of perovskite nanostructures.A survey of bandgap engineering of nanostructured perovskites is firstly presented from the aspects of dimensionality tailoring,compositional substitution,phase segregation and transition,as well as strain and pressure stimuli.The strategies of electronic doping are then reviewed,including defect-induced self-doping,inorganic or organic molecules-based chemical doping,and modification by metal ions or nanostructures.Based on the bandgap engineering and electronic doping,discussions on engineering energy band alignments in perovskite nanostructures are provided for building high-performance perovskite p-n junctions and heterostructures.At last,we provide our perspectives in engineering band structures of perovskite nanostructures towards future low-energy optoelectronics technologies. | Qingdong Ou Xiaozhi Bao Yinan Zhang Huaiyu Shao Guichuan Xing Xiangping Li Liyang Shao Qiaoliang Bao | 2019 | Nano Materials Science2019，1，4： | 5 |
| 16 | Measurement of Electric Field of Space Charge Under Positive Lightning Impulse Voltage显示文摘很多绝缘问题本质上都与电场相关,电场测量是高电压领域的重要研究手段。空间电荷导致电场畸变是流注理论的基础,因此定量测量空间电荷的泊松电场对于研究空气间隙的放电机制有重要意义。利用光电集成电场传感器测量了1m棒–板间隙未发生放电条件下各点的轴向电场,并与数值仿真结果进行对比,验证了电场传感器进行定量测量的可靠性;对3种电极条件下1m棒–板间隙空间电荷区域外部轴线上各点的电场时域波形进行测量,将空间电荷形成的泊松电场与外加电压形成的拉普拉斯电场分开,定量测量了不同电压幅值下、不同空间位置的泊松电场幅值与变化规律。研究结果为建立并验证空间电荷模型奠定了基础。 | GENG Yinan ZENG Rong ZHUANG Chijie WANG Feng | 2012 | 中国电机工程学报2012，32，22： | 5 |
| 17 | The Classical and Regulatory Functions of C1q in Immunity and Autoimmunity显示文摘A classical function of C1q is to bind immune complexes and initiate complement activation producing membrane lytic complexes,opsonins and anaphylatoxins. This classical pathway of complement activation is also elicited when C1q binds some other ligands. Besides complement activation,C1q also regulates cell differentiation,adhesion,migration,activation and survival. C1q deficiency is associated with autoimmunity as well as increased susceptibility to infections. In this article,we discuss the basic properties of C1q,its expression,and classical and regulatory functions. | Jinhua Lu Boon King Teh Linda Wang Yinan Wang Yen Seah Tan Min Chern Lai Kenneth B. M. Reid | 2008 | Cellular & Molecular Immunology2008，5，1： | 5 |
| 18 | Risks Associated with Misuse of Ketamine as a Rapid-Acting Antidepressant显示文摘Major depression is a serious psychiatric disorder and remains a leading cause of disability worldwide.Conventional antidepressants take at least several weeks to achieve a therapeutic response and this lag period has hindered their ability to attain beneficial effects in depressed individuals at high risk of suicide.The non-competitive Nmethyl-D-aspartate glutamate receptor antagonist ketamine has been shown to have rapid antidepressant effects in both rodents and humans.The emergence of ketamine as a fastacting antidepressant provides promising new insights into the development of a rapid treatment response in patients with clinical depression.However,its safety and toxicity remain a concern.In this review,we focus on the limitations of ketamine,including neurotoxicity,cognitive dysfunction,adverse events associated with mental status,psychotomimetic effects,cardiovascular events,and uropathic effects.Studies have shown that its safety and tolerability profiles are generally good at low doses and with short-term treatment in depressed patients.The adverse events associated with ketamine usually occur with very high doses that are administered for prolonged periods of time and can be relieved by cessation.The antidepressant actions of its two enantiomers,S-ketamine(esketamine) and R-ketamine,are also discussed.R-ketamine has greater antidepressant actions than S-ketamine,without ketamine-related sideeffects.Future treatment strategies should consider using Rketamine for the treatment of depressed patients to decrease the risk of adverse events associated with long-term ketamine use. | Weili Zhu Zengbo Ding Yinan Zhang Jie Shi Kenji Hashimoto Lin Lu | 2016 | Neuroscience Bulletin2016，32，6： | 5 |
| 19 | Activin A maintains cerebral cortex neuronal survival and increases voltage-gated Na^+ neuronal current显示文摘Activin A,which was first described in 1986,has been shown to maintain hippocampal neuronal survival.Activin A increases intracellular free Ca2+ via L-type Ca2+ channels.Our previous study showed that activin A promotes neurite growth of dorsal root ganglia in embryonic chickens and inhibits nitric oxide secretion.The present study demonstrated for the first time that activin A could maintain cerebral cortex neuronal survival in vitro for a long period,and that activin A was shown to increase voltage-gated Na+ current(INa) in Neuro-2a cells,which was recorded by patch clamp technique.The present study revealed a novel mechanism for activin A,as well as the influence of activin A on neurons by regulating expressions of vasoactive intestine peptide and inducible nitric oxide synthase. | Jingyan Ge Yinan Wang Haiyan Liu Fangfang Chen Xueling Cui Zhonghui Liu | 2010 | Neural Regeneration Research2010，5，19： | 4 |
| 20 | Direct Effects of Activin A on the Activation of Mouse Macrophage RAW264.7 Cells显示文摘Macrophages play critical roles in innate immune and acquired immune via secreting pro-inflammatory mediators, phagocytosing microorganisms and presenting antigens. Activin A, a member of transforming growth factor β (TGF-β) superfamily, is produced by macrophages and microglia cells. In this study, we reported a direct effect of activin A as a pro-inflammatory factor on mouse macrophage cell line RAW264.7 cells. Our data revealed that activin A could not only increase IL-1β and IL-6 production from RAW264.7 cells, but also promote pinocytic and phagocytic activities of RAW264.7 cells. In addition, activin A obviously up-regulated MHC II expression on the surface of RAW264.7 cells, whereas did not influence MHC I expression. Activin A also enhanced CD80 expression, which is a marker of activated macrophages, but did not influence RAW264.7 cell proliferation. These data suggest that activin A may regulate primary macrophage-mediated innate and acquired immune response via promoting the activation of rest macrophages. | Jingyan Ge Yinan Wang Ye Feng Haiyan Liu Xueling Cui Guixiang Tai Zhonghui Liu | 2009 | Cellular & Molecular Immunology2009，6，2： | 4 |
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