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169篇 您的检索式:作者名="Yesim"
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1Endoscopic submucosal dissection for premalignant lesions and noninvasive early gastrointestinal cancers显示文摘AIM: To investigate the indication, feasibility, safety, and clinical utility of endoscopic submucosal dissection (ESD) in the management of various gastrointestinal pathologies. METHODS: The medical records of 60 consecutive patients (34 female, 26 male) who underwent ESD at the gastroenterology department of Kocaeli University from 2006-2010 were examined. Patients selected for ESDhad premalignant lesions or non-invasive early cancers of the gastrointestinal tract and had endoscopic and histological diagnoses. Early cancers were considered to be confined to the submucosa, with no lymph node involvement by means of computed tomography and endosonography. RESULTS: Sixty ESD procedures were performed. The indications were epithelial lesions (n = 39) (33/39 adenoma with high grade dysplasia, 6/39 adenoma with low grade dysplasia), neuroendocrine tumor (n = 7), cancer (n = 7) (5/7 early colorectal cancer, 2/7 early gastric cancer), granular cell tumor (n = 3), gastrointestinal stromal tumor (n = 2), and leiomyoma (n = 2). En bloc and piecemeal resection rates were 91.6% (55/60) and 8.3% (5/60), respectively. Complete and incomplete resection rates were 96.6% (58/60) and 3.3% (2/60), respectively. Complications were major bleeding [n = 3 (5%)] and perforations [n = 5 (8.3%)] (4 colon, 1 stomach). Two patients with colonic perforations and two patients with submucosal lymphatic and microvasculature invasion (1 gastric carcinoid tumor, 1 colonic adenocarcinoma) were referred to surgery. During a mean follow-up of 12 mo, 1 patient with adenoma with high grade dysplasia underwent a second ESD procedure to resect a local recurrence. CONCLUSION: ESD is a feasible and safe method for treatment of premalignant lesions and early malignant gastrointestinal epithelial and subepithelial lesions. Successful en bloc and complete resection of lesions yield high cure rates with low recurrence.Sadettin Hulagu Omer Senturk Cem Aygun Orhan Kocaman Altay Celebi Tolga Konduk Deniz Koc Goktug Sirin Ugur Korkmaz Ali Erkan Duman Neslihan Bozkurt Gokhan Dindar Tan Attila Yesim Gurbuz Orhan TarcinDivision of Gastroenterology Derince State Hospital Kocaeli 41900 Turkey Cem Kalayci 2011World Journal of Gastroenterology2011,17,13:23
2Long-term vision-threatening complications of phakic intraocular lens implantation for high myopia显示文摘AIM:To report the long-term vision-threatening complications in patients who underwent phakic intraocular lens(pIOLs)implantation for high myopia.METHODS:Thisstudywasdesignedfromaconsecutive series of phakic intraocular lens complication and corrective surgeries.Sixteen eyes of 13 patients had implantation of phakic intraocular lens for correction high myopia and developed serious complications have been included in this study.The mean age of patients was 38.6±6.35y(range 32-50y)and the mean time of history of pIOL implantation for high myopia was 6±2y(range 2-10y).Before corrective surgery,best spectaclecorrective visual acuity(BSCVA)ranged from perception to 20/200 in the eyes in which severe complications occurred.RESULTS:Corneal decompensation occurred in 12eyes of 9 high myopic patients after anterior chamber pIOL implantation.Rhegmatogenous retinal detachment(RRD)occurred in 4 eyes of 4 high myopic patients following anterior chamber and posterior chamber pIOL implantation.Patients with corneal decompensation,had combined procedures consisting of pIOL removal and penetrating keratoplasty(PKP).Removals of pIOL,phacoemulsification and pars plana vitrectomy(PPV)with silicone oil tamponade were performed in patients with RRD.After corrective surgeries,all patients but one(P+,patient 2,right eye)achieved moderate BSCVA ranged from 20/200 to 20/50 at the last visit.CONCLUSION:Phakic IOLs may be effective for thecorrection of high myopia.Although these IOLs may have severe complications and it affects safety and efficacy of this surgery.As seen here,corneal decompensation and rhegmatogenous retinal detachment are possible postoperative vision-threatening complications of phakic IOLs.Patients must be carefully examined before and after surgery for possible endothelial cell loss and vitreoretinal problems.Isil Bahar Sayman Muslubas Baran Kandemir Ayse Yesim Aydin Oral Suleyman Kugu Metin Dastan 2014International Journal of Ophthalmology(English edition)2014,7,2:14
3Clindamycin-induced acute cholestatic hepatitis显示文摘我们为牙齿的感染在 clindamycin 的管理以后在一个 42 岁的女人报导尖锐 hepatotoxicity 的一个案例。在治疗的 6 d 以后,她有疲劳,恶心,呕吐,厌食,瘙痒和黄疸。她的实验室分析显示出丙氨酸 aminotransferase (中高音) , 1795 IU/L (正常范围 0-40 ) ;aspartate aminotransferase (著名计算机生产厂商) , 1337 IU/L (正常范围 5-34 ) ;硷性磷酸酯酶(高山) , 339 IU/L (正常范围 40-150 ) ;gamma-glutamyl transpeptidase (GGT ) , 148 IU/L (正常范围 9-64 IU/L ) ;全部的胆红素, 4.1 mg/dL;直接胆红素, 2.9 mg/dL 和前凝血酶时间(磅) , 13.5 s 与国际规范的比率(INR ) , 1.04。她被就医,与立即的药中止。她的肝活体检视标本显示出混合类型(肝细胞和胆汁郁积的) 肝的损害,与导致药的肝炎的诊断兼容。用 Naranjo 概率规模的一个客观诱发性评价建议 clindamycin 是尖锐肝炎的可能的原因。在易受影响的个人, clindamycin 使用可以导致尖锐混合类型肝毒性。如果在严重肝损伤被建立以前,这药被中止,完全的恢复可能是可能的。Cem Aygün Orhan Kocaman Yesim Gürbüz mer Sentürk Sadettin Hülagü 2007World Journal of Gastroenterology2007,13,40:6
4A predictive score for retinopathy of prematurity by using clinical risk factors and serum insulin-like growth factor-1 levels显示文摘AIM: To detect the impact of insulin-like growth factor-1(IGF-1) and other risk factors for the early prediction of retinopathy of prematurity(ROP) and to establish a scoring system for ROP prediction by using clinical criteria and serum IGF-1 levels.METHODS: The study was conducted with 127 preterm infants. IGF-1 levels in the 1 st day of life, 1 st, 2 nd, 3 rd and 4 th week of life was analyzed. The score was established after logistic regression analysis, considering the impact of each variable on the occurrences of any stage ROP. A validation cohort containing 107 preterm infants was included in the study and the predictive ability of ROP score was calculated.RESULTS: Birth weights(BW), gestational weeks(GW) and the prevalence of breast milk consumption were lower, respiratory distress syndrome(RDS), bronchopulmonarydysplasia(BPD) and necrotizing enterocolitis(NEC) were more frequent, the duration of mechanical ventilation and oxygen supplementation was longer in patients with ROP(P<0.05). Initial serum IGF-1 levels tended to be lower in newborns who developed ROP. Logistic regression analysis revealed that low BW(<1250 g), presence of intraventricular hemorrhage(IVH) and formula feeding increased the risk of ROP. Afterwards, the scoring system was validated on 107 infants. The negative predictive values of a score less than 4 were 84.3%, 74.7% and 79.8% while positive predictive values were 76.3%, 65.5% and 71.6% respectively.CONCLUSION: In addition to BW <1250 g and IVH, formula consumption was detected as a risk factor for the development of ROP. Breastfeeding is important for prevention of ROP in preterm infants.Yesim Coskun Ceyhun Dalkan Ozge Yabas Ozlem Onay Demirel Elif Samiye Bayar Sibel Sakarya Tuba Muftuoglu Dilaver Ersanli Nerin Bahceciler ipek Akman 2017International Journal of Ophthalmology(English edition)2017,10,11:4
5Fatty liver in childhood显示文摘Fatty liver is a growing health problem worldwide. It might evolve to nonalcoholic steatohepatitis, cirrhosis and cause hepatocellular carcinoma. This disease, which has increased because of eating habits, changes in food content and lifestyle, affects people from childhood. The most important risk factors are obesity and insulin resistance. Besides these factors, gender, ethnicity, genetic predisposition and some medical problems are also important. Cirrhosis in children is rare but is reported. Nonalcoholic fatty liver disease(NAFLD) has no specific symptoms or signs but should be considered in obese children. NAFLD does not have a proven treatment. Weight loss with family based treatments is the most acceptable management. Exercise and an applicable diet with low glycemic index and appropriate calorie intake are preferred. Drugs are promising but not sufficient in children for today.Yesim Ozturk Ozlem Bekem Soylu 2014World Journal of Hepatology2014,6,1:3
6Develop- ment of a multiplex and semi-nested PCR assay for detection of Yersinia enterocolitica and Aeromonas hydrophila in rawmilk显示文摘YESIM Z O LEHNER A WAGNER M 2000Food Microbiol2000,17,:1
72-Methoxyestradiol inhibils the anaphase-promoting complex and protein translation in human breast eaneer cells 显示文摘RAJENDRA B YESIM G P GEORGE W 2007Cancer Res2007,67,2:1
8Qualityassessment of wild European eel stored in ice 显示文摘Yesim Ozogul Fatih Ozogul Cengiz Giikbulut 2006FoodChemistry2006,95,3:1
9Surgical Management of Substernal Goiters: Clinical Experience of 170 Cases显示文摘Yesim Erbil Alp Bozbora Umut Barbaros Selcuk ?zarma?an Adil Azezli Senay Molvalilar 2004Surgery Today2004,,9:1
10Influence of Pulsed Inflows and Nutrient Loading on Zooplankton and Phytoplankton Community Structure and Biomass in Microcosm Experiments Using Estuarine Assemblages显示文摘Yesim Buyukates Daniel Roelke 2005Hydrobiologia2005,,1:1
11Serum levels of omentin, chemerin and adipsin in patients with biopsy-proven nonalcoholic fatty liver disease显示文摘Yusuf Yilmaz Oya Yonal Ramazan Kurt Yesim Ozen Alahdab Fatih Eren Osman Ozdogan Cigdem Ataizi Celikel Nese Imeryuz Cem Kalayci Erol Avsar 2011Scandinavian Journal of Gastroenterology2011,,1:1
12Crop water stress index for watermelon显示文摘Orta A Halim Yesim Erdem Tolga Erdem 2003Scientia Horticulturae2003,98,:1
13Postoperative medical treatment of chronic pel-vic pain related to severe endometriosis:levonorgestrel-releasing in-trauterine system versus gonadotropin-releasing hormone analogue显示文摘Yesim Bayoglu Tekin 2011Fertility and Sterility2011,95,:1
14Utilization of bentonite as a support material for immobilization of Candida rugosa lipase显示文摘Yesim Y 2005Process Biochemistry2005,40,:1
15Polypharmacyin the elderly:A multicenter study显示文摘Yesim Gokce Kutsal Anil Barak Ayce Atalay 2009Journal of the AmericanMedical Directors Association2009,10,7:1
16Effects of combining of smoking and marinating on the shelf life of anchovy stored at 4℃ 显示文摘Yesim Ozogul Fatih Ozogul Esmeray Kuley 2010Food Science and Biotechnol2010,19,1:1
17Extended release lipophilic indomethacin microspheres:formulation factors and mathematical equations fitted drug release rates显示文摘KARASULU E YESIM KARASULU H ERTAN G 2003Eur J Pharm Sci2003,19,23:1
18Adsorption behavior of Cr (Ⅵ) on activated hazelnut shell ash and activated bentonite 显示文摘Yuksel Bayrak Yesim Yesiloglu and Unal Gecgel 2006Microporous and Mesoporous Materials2006,91,13:1
19Fatty acid profiles and fat contents of commercially important seawater and freshwater fish species of Turkey: A comparative study显示文摘Yesim ?zogul Fatih ?zogul Sibel Alagoz 2006Food Chemistry2006,,1:1
20Importance of microbi-ological e-valuation in management of infectious complica-tions following pecutaneous nephrolithotomy显示文摘Hasan SD Fuad G Yesim S 2007Int UrolNephrol2007,39,2:1
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