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14篇 您的检索式:作者名="Yanxia Fu"
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1Numerical simulation of leading edge cavitation within the whole flow passage of a centrifugal pump显示文摘In this paper, the periodically unsteady pressure field and head-drop phenomenon caused by leading edge cavitation have been investigated numerically by computational fluid dynamics (CFD) in a single stage centrifugal pump. A CFD model for cavitation steady and unsteady simulation has been calculated using the k-ω SST turbulence model combining with a multiphase approach, based on a homogeneous model assumption. A truncated form of Rayleigh-Plesset equation is used as a source term for the inter-phase mass transfer. The CFD computational region includes the suction cone, impeller, side chambers and volute, as well as suction and pressure pipes. The results were compared with experimental data under non-cavitation and cavitation conditions and a good agreement was obtained for the global performance, the experimental data of the head and the efficiency are 34.04 m and 74.42% at BEP, respectively, the predicted head is 34.31 m and the predicted efficiency is 73.75%. The analysis of inner flow pattern shows that the vortex flow generation in the rear of cavity region is the main reason of the head-drop. Obvious increasing can be observed for the amplitude of the pressure fluctuation at the blade passing frequency with different cavitation situations, and subpeak can be found. Besides, the effects of unsteady flow in the side chambers cannot be neglected for accurately predicting the inner flow of the pump. These results imply that this numerical method is suitable for the cavitating flow in the pump.LI XiaoJun YUAN ShouQi PAN ZhongYong YUAN JianPing FU YanXia 2013Science China(Technological Sciences)2013,56,9:14
2Satellite-observed trends in the Arctic sea ice concentration for the period 1979–2016显示文摘Arctic sea ice cover has decreased dramatically over the last three decades. This study quanti?es the sea ice concentration(SIC) trends in the Arctic Ocean over the period of 1979–2016 and analyzes their spatial and temporal variations. During each month the SIC trends are negative over the Arctic Ocean, wherein the largest(smallest) rate of decline found in September(March) is-0.48%/a(-0.10%/a).The summer(-0.42%/a) and autumn(-0.31%/a) seasons show faster decrease rates than those of winter(-0.12%/a) and spring(-0.20%/a) seasons. Regional variability is large in the annual SIC trend. The largest SIC trends are observed for the Kara(-0.60%/a) and Barents Seas(-0.54%/a), followed by the Chukchi Sea(-0.48%/a), East Siberian Sea(-0.43%/a), Laptev Sea(-0.38%/a), and Beaufort Sea(-0.36%/a). The annual SIC trend for the whole Arctic Ocean is-0.26%/a over the same period. Furthermore, the in?uences and feedbacks between the SIC and three climate indexes and three climatic parameters, including the Arctic Oscillation(AO), North Atlantic Oscillation(NAO), Dipole anomaly(DA), sea surface temperature(SST), surface air temperature(SAT), and surface wind(SW), are investigated. Statistically, sea ice provides memory for the Arctic climate system so that changes in SIC driven by the climate indices(AO, NAO and DA) can be felt during the ensuing seasons. Positive SST trends can cause greater SIC reductions, which is observed in the Greenland and Barents Seas during the autumn and winter. In contrast, the removal of sea ice(i.e., loss of the insulating layer) likely contributes to a colder sea surface(i.e., decreased SST), as is observed in northern Barents Sea. Decreasing SIC trends can lead to an in-phase enhancement of SAT, while SAT variations seem to have a lagged in?uence on SIC trends. SW plays an important role in the modulating SIC trends in two ways: by transporting moist and warm air that melts sea ice in peripheral seas(typically evident inthe Barents Sea) and by exporting sea ice out of the Arctic Ocean via passages into the Greenland and Barents Seas, including the Fram Strait, the passage between Svalbard and Franz Josef Land(S-FJL),and the passage between Franz Josef Land and Severnaya Zemlya(FJL-SZ).WANG Yunhe BI Haibo HUANG Haijun LIU Yanxia LIU Yilin LIANG Xi FU Min ZHANG Zehua 2019Journal of Oceanology and Limnology2019,37,1:7
3Application of regional citrate anticoagulation in patients at high risk of bleeding during intermittent hemodialysis:a prospective multicenter randomized controlled trial显示文摘Objective:Safe and effective anticoagulation is essential for hemodialysis patients who are at high risk of bleeding.The purpose of this trial is to evaluate the effectiveness and safety of two-stage regional citrate anticoagulation(RCA)combined with sequential anticoagulation and standard calcium-containing dialysate in intermittent hemodialysis(IHD)treatment.Methods:Patients at high risk of bleeding who underwent IHD from September 2019 to May 2021 were prospectively enrolled in 13 blood purification centers of nephrology departments,and were randomly divided into RCA group and saline flushing group.In the RCA group,0.04 g/mL sodium citrate was infused from the start of the dialysis line during blood draining and at the venous expansion chamber.The sodium citrate was stopped after 3 h of dialysis,which was changed to sequential dialysis without anticoagulant.The hazard ratios for coagulation were according to baseline.Results:A total of 159 patients and 208 sessions were enrolled,including RCA group(80 patients,110 sessions)and saline flushing group(79 patients,98 sessions).The incidence of severe coagulation events of extracorporeal circulation in the RCA group was significantly lower than that in the saline flushing group(3.64%vs.20.41%,P<0.001).The survival time of the filter pipeline in the RCA group was significantly longer than that in the saline flushing group((238.34±9.33)min vs.(221.73±34.10)min,P<0.001).The urea clearance index(Kt/V)in the RCA group was similar to that in the saline flushing group with no statistically significant difference(1.12±0.34 vs.1.08±0.34,P=0.41).Conclusions:Compared with saline flushing,the two-stage RCA combined with a sequential anticoagulation strategy significantly reduced extracorporeal circulation clotting events and prolonged the dialysis time without serious adverse events.Xiaoyan TANG Dezheng CHEN Ling ZHANG Ping FU Yanxia CHEN Zhou XIAO Xiangcheng XIAO Weisheng PENG Li CHENG Yanmin ZHANG Hongbo LI Kehui LI Bizhen GOU Xin WU Qian YU Lijun JIAN Zaizhi ZHU Yu WEN Cheng LIU Hen XUE Hongyu ZHANG Xin HE Bin YAN Liping ZHONG Bin HUANG Mingying MAO 2022Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2022,23,11:4
4Defect engineering of molybdenum disulfide through ion irradiation to boost hydrogen evolution reaction performance显示文摘The inert basal plane of molybdenum disulfide (MoS2) restrains its further hydrogen evolution reaction (HER) performance.This work attempts ion irradiation to activate inert basal plane of MoS2 nanosheet to improve its electrocatalytic performance.Experimental results demonstrate the sulphur vacancies generated by ion irradiation on the basal plane of MoS2 mainly boost the efficiency of HER performance.The moderate fluence of carbon ion irradiation gains the optimum HER performance with an onset potential of 77 mV and Tafel slope of 66 mV/dec.Cheng Sun Peipei Wang Hao Wang Chuan Xu Juntong Zhu Yanxia Liang Ying Su Yining Jiang Wenqi Wu Engang Fu Guifu Zou 2019Nano Research2019,12,7:3
5A shedding soluble form of interleukin-17 receptor D exacerbates collagen-induced arthritis through facilitating TNF-α-dependent receptor clustering显示文摘Rheumatoid arthritis(RA)is exacerbated by TNF-alpha signaling.However,it remains unclear whether TNF-α-activated TNFR1 and TNFR2 are regulated by extracellular factors.Here,we showed that soluble glycosylated interleukin-17 receptor D(sIL-17RD),which was produced by proteolytic cleavage,enhanced TNF-α-induced RA.We revealed that IL-17RD shedding was induced by the proteolytic enzyme TACE and enhanced by TNF-αexpression in macrophages.Intriguingly,sIL-17RD was elevated in the sera of arthritic mice and rats.Recombinant sIL-17RD significantly enhanced the TNF-α-induced proinflammatory response by promoting TNF-α-TNFR-sIL-17RD complex formation and receptor clustering,leading to the accelerated development of collagen-induced arthritis.Our observations revealed that ectodomain shedding of IL-17RD occurred in RA to boost the TNF-α-induced inflammatory response.Targeting sIL-17RD may provide a new strategy for the therapy of RA.Sihan Liu Yanxia Fu Kunrong Mei Yinan Jiang Xiaojun Sun Yinyin Wang Fangli Ren Congshan Jiang Liesu Meng Shemin Lu Zhihai Qin Chen Dong Xinquan Wang Zhijie Chang Shigao Yang 2021Cellular & Molecular Immunology2021,18,8:1
6Enantioseparation by HPLC Using an Inorganic Chiral Mesoporous Silica with Highly-ordered Structure显示文摘Highly-ordered inorganic chiral mesoporous silica(HOCMS)has attracted substantial interest in recent decades.High performance liquid chromatography(HPLC)is the most important approach for the separation of enantiomers and herein reported an HPLC chiral stationary phase composed of HOCMS.The column was fabricated by conventional high pressure slurry packing.Eighteen racemates,including alcohols,ketones,amines,aldehydes and organic acids,were resolved on the column.Good chiral separations of hydrobenzoin,metoprolol,propranolol hydrochloride,4-methyl-2-pentanol,omeprazole,2,2′-furoin and ketoprofen were obtained.The relative standard devi-ations for five replicate separations of racemates were 0.1%–0.16%for retention time and 1.73%–2.64%for peak areas.The results suggest that HOCMS is a promising candidate for preparation of chiral stationary phases for HPLC.PENG Bo FU Shiguo LI Yanxia ZHANG Junhui XIE Shengming LI Li LYU Yun DU AN Aihong CHEN Xuexian YUAN Liming 2019Chemical Research in Chinese Universities2019,35,6:1
7Numerical and experimental analysis of flow phenomena in a centrifugal pump operating under low flow rates显示文摘FU Yanxia YUAN Jianping YUAN Shouqi 2015Journal of Fluids Engineering2015,137,01:1
8Robust optimization design on impeller of mixed-flow pump显示文摘To increase the robustness of the optimization solutions of the mixed-flow pump,the impeller was firstly indirectly parameterized based on the 2D blade design theory.Secondly,the robustness of the optimization solution was mathematically defined,and then calculated by Monte Carlo sampling method.Thirdly,the optimization on the mixed-flow pump′s impeller was decomposed into the optimal and robust sub-optimization problems,to maximize the pump head and efficiency and minimize the fluctuation degree of them under varying working conditions at the same time.Fourthly,using response surface model,a surrogate model was established between the optimization objectives and control variables of the shape of the impeller.Finally,based on a multi-objective genetic optimization algorithm,a two-loop iterative optimization process was designed to find the optimal solution with good robustness.Comparing the original and optimized pump,it is found that the internal flow field of the optimized pump has been improved under various operating conditions,the hydraulic performance has been improved consequently,and the range of high efficient zone has also been widened.Besides,with the changing of working conditions,the change trend of the hydraulic performance of the optimized pump becomes gentler,the flow field distribution is more uniform,and the influence degree of the varia-tion of working conditions decreases,and the operating stability of the pump is improved.It is concluded that the robust optimization method proposed in this paper is a reasonable way to optimize the mixed-flow pump,and provides references for optimization problems of other fluid machinery.ZHAO Binjuan LIAO Wenyan XIE Yuntong HAN Luyao FU Yanxia HUANG Zhongfu 2021排灌机械工程学报2021,39,7:0
9LA SYNOPSIS DE ELECTROENCEPHALOQUADRANTOGRAMME(EEQG)显示文摘EEQG est inventépar professeur Dekun Wang of shanxi institut de médecin chinoise traditionnelle et est mieux recherchéet développépar professeur Baoyun Yan et Qingrui Liu etc,de vice rédacteur en chef de journal de moderne electrophysiologie et produit par Tianjin Hede sciences et techniques et développement sociétéanonyme.Il est produit premier dans notre gays etMingshun Liu 闫宝云 Qingrui Liu Yanxia Fu 2015现代电生理学杂志2015,22,1:0
10Investigation of transfer ionization processes in the collision of partially stripped carbon ions on Argon显示文摘The ratios of the cross section of the transfer-ionization to the single-electron-capture of Argon induced by Cq+ (q=1,2,3) ions are measured by means of position sensitive and time-of-flight techniques. Our experimental results are compared with the data of Heq+ (q=1,2)-Ar of DuBois. A qualitative interpretation is presented based on the Classical-Over-Barrier Model of Bohr.WANG Jun CHEN XiMeng DING BaoWei FU HongBin CUI Ying SHAO JianXiong LU YanXia GAO ZhiMin LIU YuWen Du Juan SUN GuangZhi CHEN Lin 2008Science China(Physics,Mechanics & Astronomy)2008,51,7:0
11CONTRAST ANALYSIS ON ECG,CT AND CLINICAL MANIFESTATION OF PATIENTS OVER SEVENTY YEARS OLD WITH STROKE显示文摘目的:探讨70岁以上老年人脑卒中患者的心电图、CT和临床表现的特点及其预防和治疗方法。方法:100例患者的心电图、CT和临床表现被分析了。结果:这些患者的心电图和CT改变以及临床表现是各不相同的。结论:70岁以上老年人的脑卒中患者是具有一定特点的。Mingshun Liu Yanxia Fu Ran Liu Po Ma 2008现代电生理学杂志2008,15,1:0
12CONTRAST STUDY ON BA AND CT IN PATIENTS WITH POST-TRAUMATIC BRAIN SYNDROME显示文摘目的:探讨脑电地形图与脑 CT 在脑外伤后综合征患者诊断中的应用价值。方法:103 例脑外伤后综合征患者进行了脑电地形图和脑 CT 检查,并进行对比。结果:在脑外伤后综合征患者中,脑电地形图显示阳性改变,而脑 CT 为阴性。结论:脑电地形图在脑外伤后综合征患者的诊断中有重要应用价值。Mingshun Liu Po Ma Yanxia Fu 2012现代电生理学杂志2012,19,4:0
13New insights into the correlations between circulating tumor cells and target organ metastasis显示文摘Organ-specific metastasis is the primary cause of cancer patient death.The distant metastasis of tumor cells to specific organs depends on both the intrinsic characteristics of the tumor cells and extrinsic factors in their microenvironment.During an intermediate stage of metastasis,circulating tumor cells(CTCs)are released into the bloodstream from primary and metastatic tumors.CTCs harboring aggressive or metastatic features can extravasate to remote sites for continuous colonizing growth,leading to further lesions.In the past decade,numerous studies demonstrated that CTCs exhibited huge clinical value including predicting distant metastasis,assessing prognosis and monitoring treatment response et al.Furthermore,increasingly numerous experiments are dedicated to identifying the key molecules on or inside CTCs and exploring how they mediate CTC-related organ-specific metastasis.Based on the above molecules,more and more inhibitors are being developed to target CTCs and being utilized to completely clean CTCs,which should provide promising prospects to administer advanced tumor.Recently,the application of various nanomaterials and microfluidic technologies in CTCs enrichment technology has assisted to improve our deep insights into the phenotypic characteristics and biological functions of CTCs as a potential therapy target,which may pave the way for us to make practical clinical strategies.In the present review,we mainly focus on the role of CTCs being involved in targeted organ metastasis,especially the latest molecular mechanism research and clinical intervention strategies related to CTCs.Qinru Zhan Bixia Liu Xiaohua Situ Yuting Luo Tongze Fu Yanxia Wang Zhongpeng Xie Lijuan Ren Ying Zhu Weiling He Zunfu Ke 2024Signal Transduction and Targeted Therapy2024,9,1:0
14Influence of specific speed on hydraulic performances and pressure fluctuations in mixed-flow pumps显示文摘A series of steady and unsteady numerical calculations of the internal flow in mixed-flow pumps with three different specific speeds were carried out based on the N-S equation coupled with the standard k-εturbulence model under different operating conditions to investigate the relationship between the impeller specific speed and the pump performance as well as pressure pulsations.Meanwhile,the pump performance and pressure pulsations inside the mixed-flow pump with three different specific speeds were also analyzed and compared with the corresponding test data.From the results,the averaged deviations between the predicted and tested head among different impellers are below 5%,and with respect to the equivalent impeller specific speeds of 280 and 260,the values are 4.30%and 3.69%,respectively.For all the impeller schemes,the best efficiency point of the mixed-flow pump is found at the flow rate of 1.2 Q_(d) and the higher head deviation occurs at lower flow rates.Especially,it can be found that the specific speed has a slight effect on the pressure fluctuation in the impellers.Eventually,it is determined that the pump performance curves calculated by numerical simu-lations have good agreement with the relevant experimental results,which verifies that the numerical methods used in the present study are accurate to a certain extent.Furthermore,the results also provide some references to the pressure pulsation analysis and the performance improvement of the mixed-flow pump design.FU Yanxia JIA Qi SHEN Yang PACE Giovanni 2023排灌机械工程学报2023,41,10:0
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