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| 1 | USP3 inhibits type I interferon signaling by deubiquitinating RIG-I-like receptors显示文摘(K63 ) 离氨酸 63 连接了 RIG-I 戏的 ubiquitination 在类型的激活的一个关键角色我干扰素小径,然而,为它的 deubiquitination 负责的分子的机制仍然糟糕被理解。这里,我们报导 deubiquitination 酶 ubiquitin 特定的朊酶(USP3 ) 3 否定地调整类型的激活我干扰素由指向 RIG-I 发信号。USP3 击倒 RIG-I 的明确地提高的连接 K63 的 ubiquitination, upregulated IRF3 的 phosphorylation 并且扩充了类型的生产我干扰素 cytokines 和抗病毒的免疫。我们进一步证明在 unstimulated 或 uninfected 房间在 USP3 和 RIG-I-like 受体( RLR )之间没有相互作用,但是在病毒的感染或 ligand 刺激之上, USP3 绑在 RLR 的 caspase 激活招募领域然后通过它的锌手指的合作劈开 polyubiquitin 链Ub有约束力的领域和 USP 催化领域。变化分析表明到 RIG-I 上的 polyubiquitin 链的 USP3 的那绑定是为它 polyubiquitin 链的劈开的前提步。我们的调查结果在 RIG-I 激活识别 USP3 的一个以前未被认出的角色并且提供卓见进 USP3 由禁止 RIG-I 发信号和抗病毒的免疫的机制。 | Jun Cui Yanxia Song Yinyin Li Qingyuan Zhu Peng Tan Yunfei Qin Helen Y Wang Rong-Fu Wang | 2014 | Cell Research2014，24，4： | 20 |
| 2 | Tiny YOLO Optimization Oriented Bus Passenger Object Detection显示文摘The real-time collection of bus passenger object detection is an essential part of developing a smart bus system.The difficulty of object detection mainly lies in the objective factors,such as:clothing,hair style and accessories,light,etc.Traditional object detection met hods with the arti ficial feature ext rac tion suffers from insufficien t st reng th in expression,generalization,and recogni tion rate.The objec t detection met hod based on deep learning mainly uses the convol utio nal neural net work in deep learning to learn features from a large set of data.The learned features can describe the rich infbrmation inherent in the data,and improve the expression ability of the features as well as the recognition accuracy.Due to too many parameters of the Convolutional neural network(CNN)model,the amount of calculation is too large to be opera ted on the vehicle terminal.To reduce calculation burden and improve the operation speed,we employs the depthwise separable convolution method to optimize the convolutional layer of tiny YOLO net work model.It decomposes a complete convolution operation into depthwise convolution and pointwise convolution,thus reducing the parameter amount of the CNN and improving the operation speed.The experiment results reveal that the speed of bus passenger object detection detected by our improved model is 4 times faster than the previous one but with the nearly same detection accuracy. | ZHANG Shuo WU Yanxia MEN Chaoguang LI Xiaosong | 2020 | Chinese Journal of Electronics2020，29，1： | 15 |
| 3 | Numerical simulation of leading edge cavitation within the whole flow passage of a centrifugal pump显示文摘In this paper, the periodically unsteady pressure field and head-drop phenomenon caused by leading edge cavitation have been investigated numerically by computational fluid dynamics (CFD) in a single stage centrifugal pump. A CFD model for cavitation steady and unsteady simulation has been calculated using the k-ω SST turbulence model combining with a multiphase approach, based on a homogeneous model assumption. A truncated form of Rayleigh-Plesset equation is used as a source term for the inter-phase mass transfer. The CFD computational region includes the suction cone, impeller, side chambers and volute, as well as suction and pressure pipes. The results were compared with experimental data under non-cavitation and cavitation conditions and a good agreement was obtained for the global performance, the experimental data of the head and the efficiency are 34.04 m and 74.42% at BEP, respectively, the predicted head is 34.31 m and the predicted efficiency is 73.75%. The analysis of inner flow pattern shows that the vortex flow generation in the rear of cavity region is the main reason of the head-drop. Obvious increasing can be observed for the amplitude of the pressure fluctuation at the blade passing frequency with different cavitation situations, and subpeak can be found. Besides, the effects of unsteady flow in the side chambers cannot be neglected for accurately predicting the inner flow of the pump. These results imply that this numerical method is suitable for the cavitating flow in the pump. | LI XiaoJun YUAN ShouQi PAN ZhongYong YUAN JianPing FU YanXia | 2013 | Science China(Technological Sciences)2013，56，9： | 14 |
| 4 | Effectiveness of Jinying capsule on pelvic inflammatory disease in patients with symptom pattern of damp and heat accumulation: a double-blinded, multicenter, randomized, placebo-controlled clinical trial显示文摘OBJECTIVE: To evaluate the therapeutic effectiveness and safety of Jinying capsule on pelvic inflammatory disease(PID) in patients with symptoms identified as the pattern of damp and heat accumulation in terms of Traditional Chinese Medicine(TCM).METHODS: We conducted a double-blinded, multicenter, randomized, placebo-controlled clinical trial which included 155 patients diagnosed with PID and identified as symptom pattern of damp and heat accumulation. They were randomly divided into experimental group(n = 78) and control group(n = 77) according to a random number table. The treatment lasted for a period of 28 d. The experimental group was given Jinying capsules and oral levofloxacin plus oral metronidazole for first 7 d.They continued with Jinying capsules and levofloxacin placebo and metronidazole placebo for another 7 d. For the remaining 14 d, they continued with Jinying capsules only. Whereas, the control group was treated with oral levofloxacin and metronidazole and Jinying capsule placebo for the first 14 d in the same way as the experimental group and then continued with Jinying capsule placebo only for the remaining 14 d. The clinical efficacy was assessed using McCormack scale, TCM symptom pattern scores, physicochemical indexes including white blood cell and erythrocyte sedimentation rate, C-reaction protein, smear of vaginal discharge,and pelvic ultrasound.RESULTS: Comparing McCormack scale between both groups after treatment, the difference in curative effect between both groups was significant (P = 0.0269). The cure rate of the experimental group and control group is 76.32% and 59.46% respectively at week 4. Comparing TCM symptom pattern scores between both groups before and after treatment, the differences in total effective rate were both significant(P < 0.05). The curative effect rate of experimental group is 2.63% and 13.70% of the control group at week 1(P = 0.0131), and73.33% of the experimental group and 56.94% of the control group at week 4(P = 0.0369). No significant differences were found between the two groups on the Physicochemical indexes(all P >0.05). No adverse events or reactions occurred in the experimental groups.CONCLUSION: Jinying capsule can reduce the dosage of antibiotics needed for PID treatment, and improve the symptoms in PID patients. | Yang Yan Lu Yao Zhou Deping Pei Fenglan Li Qin Chen Shuqiong Wang Qiufeng Wang Yanting Jin Zhe Liu Yanxia | 2020 | Journal of Traditional Chinese Medicine2020，40，3： | 10 |
| 5 | A human circulating immune cell landscape in aging and COVID-19显示文摘Age-associated changes in immune cells have been linked to an increased risk for infection.However,a global and detailed characterization of the changes that human circulating immune cells undergo with age is lacking.Here,we combined scRNA-seq,mass cytometry and sCATAC-seq to compare immune cell types in peripheral blood collected from young and old subjects and patients with COVID-19.We found that the immune cell landscape was reprogrammed with age and was characterized by T cell polarization from naive and memory cells to effector,cytotoxic,exhausted and reg-ulatory cells,along with increased late natural killer cells,age-associated B cells,inflammatory monocytes and age-associated dendritic cells.In addition,the expression of genes,which were implicated in coron-avirus susceptibility,was upregulated in a cell subtype-specific manner with age.Notably,COVID-19 promoted age-induced immune cell polarization and gene expression related to inflammation and cellular senes-cence.Therefore,these findings suggest that a dysreg-ulated immune system and increased gene expression associated with SARS-CoV-2 susceptibility may at least partially account for COVID-19 vulnerability in the elderly. | Yingfeng Zheng Xiuxing Liu Wenqing Le Lihui Xie He Li Wen Wen Si Wang Shuai Ma Zhaohao Huang Jinguo Ye Wen Shi Yanxia Ye Zunpeng Liu Moshi Song Weiqi Zhang Jing-Dong J.Han Juan Carlos lzpisua Belmonte Chuanle Xiao Jing Qu Hongyang Wang Guang-Hui Liu Wenru Su | 2020 | Protein & Cell2020，11，10： | 10 |
| 6 | Vitamin C alleviates aging defects in a stem cell model for Werner syndrome显示文摘沃纳症候群(WS ) 是主要影响从中层导出的纸巾的早衰混乱。我们最近用 WRN 缺乏的人的间充质的干细胞(MSC ) 开发了一个新奇人的 WS 模型。这个模型概括 WS 的许多 phenotypic 特征。基于很多化学药品的一幅屏幕,这里,我们发现维生素 C 在出现在WRN缺乏的 MSC 的早衰为许多特征施加很有效的营救包括细胞生长拘捕,增加了反应的氧种层次, telomere 摩擦,煽动性的因素的过多的分泌物,象原子薄板和 heterochromatin 的组织的破坏一样。而且,维生素 C 在一个老鼠模型在 vivo 恢复 MSC 的生存能力。定序分析的 RNA 显示维生素 C 改变涉及染色质冷凝作用,房间周期规定, DNA 复制,和 DNA 损坏的一系列基因的表示在 WRN 缺乏的 MSC 的修理小径。我们的结果为 WS MSC 作为一个恢复因素识别维生素 C,它保持作为 WS 的处理的一种新奇类型被使用的潜力。 | Ying Li Weizhou Zhang Liang Chang Yan Han Liang Sun Xiaojun Gong Hong Tang Zunpeng Liu Huichao Deng Yanxia Ye Yu Wang Jian Li Jie Qiao Jing Qu Weiqi Zhang Guang-Hui Liu | 2016 | Protein & Cell2016，7，7： | 10 |
| 7 | Expression of HMGB2 indicates worse survival of patients and is required for the maintenance of Warburg effect in pancreatic cancer显示文摘高活动性组蛋白质(HMG ) 是第二很丰富的染色质蛋白质并且在活跃或不活跃的染色质域的建立施加全球 genomic 函数。通过和 nucleosomes,抄写因素,改变 nucleosome 机器和 histones 的相互作用, HMG 家庭蛋白质贡献响应快速的环境变化抄写调节的罚款。哺乳动物的高活动性组 B (HMGB ) 被领域用一条长酸的尾巴跟随了的二个双人脚踏车 HMG 盒子描绘。最近的研究证明 HMGB 的那高表情在许多癌症被发现了,例如前列腺,肾,卵巢、胃的癌症。然而,他们在胰腺的癌症的角色很少被报导了。在这研究,我们估计了 HMGB 蛋白质的诊断、预示的值,包括 HMGB1, HMGB2,和 HMGB3,在从癌症染色体地图集(TCGA ) 数据集的胰腺的癌症。我们的结果证明 HMGB2 在胰腺的癌症预言了差的预后。在 vitro,研究证明 silencing HMGB2 禁止了房间增长和生存能力。机械学地,我们的结果证明 silencing HMGB2 减少了组织缺氧可诱导的因素 1 (HIF1 ) 蛋白质水平和禁止的调停 HIF1 的 glycolysis 处理。进一步的分析显示包括 GLUT1, HK2,和 LDHA,指向 HIF1 的 glycolytic 基因都是预示的因素并且断然与 HMGB2 表示相关。一起拿,我们为胰腺的癌症发现了新预示、预兆的标记,并且在癌症在 glycolytic 控制使 HMGB2 的新奇函数清楚些。 | Xin Cai Hongjian Ding Yanxia Liu Gaofeng Pan Qingguo Li Zhen Yang Weiyan Liu | 2017 | Acta Biochimica et Biophysica Sinica2017，49，2： | 9 |
| 8 | Analysis of the microbiota of sputum samples from patients with lower respiratory tract infections显示文摘唾沫是从患更低的呼吸的道感染的病人收集的最普通的样品,它为这些感染的细菌的鉴定是关键的。在这研究,我们与更低的呼吸的道感染从 101 个病人注册了 101 件唾沫样品。开始,在唾沫包含的细菌的 16S rDNA V3 hypervariable 区域的 pyrosequencing 为 microbiota 分析作为一条文化无关的途径被利用。为比较,用一个文化依赖者的临床的实验室测试为样品也被做的唾沫的一样的队自动化了细菌的鉴定系统。由 pyrosequencing, > 70,000 DNA 碎片在被 Ribosomal 数据库工程(RDP ) 过程分析以后被发现并且分类进 129 个细菌的类。大多数序列属于几个占优势的类,例如链球菌和葡萄球菌,显示这些类起在更低的呼吸的道感染的一个重要作用。另外,属于潜在的原因的代理人的一些序列例如霉浆菌, Haemophilus,和 Moraxella,也被发现,但是这些序列没被临床的实验室测试发现。为两个方法检测的九个类,方法的敏感被比较,结果证明 pyrosequencing 是更敏感的,除了 Klebsiella 和 Mycobacterium。显著地,这个方法揭示了更复杂的细菌的社区,它为细菌的察觉显示出一个有希望的能力。 | Yuhua Zhou Ping Lin Qingtian Li Lizhong Han Huajun Zheng Yanxia Wei Zelin Cui Yuxing Ni Xiaokui Guo | 2010 | Acta Biochimica et Biophysica Sinica2010，42，10： | 8 |
| 9 | Comparative study on skin temperature response to menstruation at acupuncture points in healthy volunteers and primary dysmenorrhea patients显示文摘OBJECTIVE:To assess skin temperature response to menstruation at acupuncture points in primary dysmenorrhea(PD) patients and healthy volunteers so as to explore acupuncture point specificity in reflecting diseases in the light of skin temperature.METHODS:Fifty-two PD patients and 49 healthy volunteers were recruited.Skin temperature measurements were performed with a skin temperature assessment device at 10 points.Absolute difference between skin temperature of the same point on the left and right side is used as main outcome measure.RESULTS:On the first day of menstruation, when menstrual pain attacking in PD patients, a significant increase in skin temperature difference was detected at Taixi(KI 3) compared with the healthy group(P < 0.01).A significant reduction in skin temperature difference was detected at Taixi(KI 3) in the first day of menstruation compared with those values in the third day after menstruation(P < 0.01)in the healthy group.On the third day after menstruation, a significant reduction in skin temperature difference was found at Zhongdu(LR 6) in PD group compared with the healthy group(P < 0.05).No significant differences of skin temperature were detected at other points(P > 0.05).CONCLUSION:The skin temperature difference at menstruation-relevant points in PD patients did not all change significantly more than those in women without PD.Significant difference was only found in Taixi(KI 3), the Yuan-source point of Kidney meridian. | She Yanfen Ma Liangxiao Zhu Jiang Qi Conghui Wang Yanxia Tang Ling Li Chunhua Yuan Hongwen Liu Yuqi Song Jiashan | 2017 | Journal of Traditional Chinese Medicine2017，37，2： | 8 |
| 10 | Developing superior alleles of yield genes in rice by artificial mutagenesis using the CRISPR/Cas9 system显示文摘Rice yield is an important and complex agronomic trait controlled by multiple genes.In recent decades,dozens of yield-associated genes in rice have been cloned,many of which can increase production in the form of loss or degeneration of function.However,mutations occurring randomly under natural conditions have provided very limited genetic resources for yield increases.In this study,potentially yield-increasing alleles of two genes closely associated with yield were edited artificially.The recently developed CRISPR/Cas9system was used to edit two yield genes:Grain number 1a(Gn1a)and DENSE AND ERECT PANICLE1(DEP1).Several mutants were identified by a target sequence analysis.Phenotypic analysis confirmed one mutant allele of Gn1a and three of DEP1 conferring yield superior to that conferred by other natural high-yield alleles.Our results demonstrate that favorable alleles of the Gnla and DEP1 genes,which are considered key factors in rice yield increases,could be developed by artificial mutagenesis using genome editing technology. | Liyu Huang Ru Zhang Guangfu Huang Yanxia Li Getachew Melaku Shilai Zhang Haitao Chen Yanjuan Zhao Jing Zhang Yesheng Zhang Fengyi Hu | 2018 | The Crop Journal2018，6，5： | 8 |
| 11 | Release of VEGF and BMP9 from injectable alginate based composite hydrogel for treatment of myocardial infarction显示文摘Myocardial infarction(MI)is one of cardiovascular diseases that pose a serious threat to human health.The pathophysiology of MI is complex and contains several sequential phases including blockage of a coronary artery,necrosis of myocardial cells,inflammation,and myocardial fibrosis.Aiming at the treatment of different stages of MI,in this work,an injectable alginate based composite hydrogel is developed to load vascular endothelial active factor(VEGF)and silk fibroin(SF)microspheres containing bone morphogenetic protein 9(BMP9)for releasing VEGF and BMP9 to realize their respective functions.The results of in vitro experiments indicate a rapid initial release of VEGF during the first few days and a relatively slow and sustained release of BMP9 for days,facilitating the formation of blood vessels in the early stage and inhibiting myocardial fibrosis in the long-term stage,respectively.Intramyocardial injection of such composite hydrogel into the infarct border zone of mice MI model via multiple points promotes angiogenesis and reduces the infarction size.Taken together,these results indicate that the dual-release of VEGF and BMP9 from the composite hydrogel results in a collaborative effect on the treatment of MI and improvement of heart function,showing a promising potential for cardiac clinical application. | Yong Wu Tianqi Chang Weiqian Chen Xiaoyu Wang Jingjing Li Yueqiu Chen You Yu Zhenya Shen Qian Yu Yanxia Zhang | 2021 | Bioactive Materials2021，6，2： | 7 |
| 12 | Immunity-and-matrix-regulatory cells derived from human embryonic stem cells safely and effectively treat mouse lung injury and fibrosis显示文摘Lung injury and fibrosis represent the most significant outcomes of severe and acute lung disorders,including COVID-19.However,there are still no effective drugs to treat lung injury and fibrosis.In this study,we report the generation of clinical-grade human embryonic stem cells(hESCs)-derived immunity-and matrix-regulatory cells(IMRCs)produced under good manufacturing practice requirements,that can treat lung injury and fibrosis in vivo.We generate IMRCs by sequentially differentiating hESCs with serum-free reagents.IMRCs possess a unique gene expression profile distinct from that of umbilical cord mesenchymal stem cells(UCMSCs),such as higher expression levels of proliferative,immunomodulatory and anti-fibrotic genes.Moreover,intravenous delivery of IMRCs inhibits both pulmonary inflammation and fibrosis in mouse models of lung injury,and significantly improves the survival rate of the recipient mice in a dose-dependent manner,likely through paracrine regulatory mechanisms.IMRCs are superior to both primary UCMSCs and the FDA-approved drug pirfenidone,with an excellent efficacy and safety profile in mice and monkeys.In light of public health crises involving pneumonia,acute lung injury and acute respiratory distress syndrome,our findings suggest that IMRCs are ready for clinical trials on lung disorders. | Jun Wu Dingyun Song Zhongwen Li Baojie Guo Yani Xiao Wenjing Liu Lingmin Liang Chunjing Feng Tingting Gao Yanxia Chen Ying Li Zai Wang Jianyan Wen Shengnan Yang Peipei Liu Lei Wang Yukai Wang Liang Peng Glyn Nigel Stacey Zheng Hu Guihai Feng Wei Li Yan Huo Ronghua Jin Ng Shyh-Chang Qi Zhou Liu Wang Baoyang Hu Huaping Dai Jie Hao | 2020 | Cell Research2020，30，9： | 7 |
| 13 | Investigation of carbon fiber composite stiffened skin with vacuum assisted resin infusion/prepreg co-curing process显示文摘Co-cured vacuum assisted resin infusion process(co-VARI process),which combined vacuum assisted resin infusion(VARI)with prepreg vacuum bag only process(VBO),was adopted to fabricate T-shaped stiffened skin with non-crimp fabric(NCF)stiffener and prepreg skin.During compaction stage of co-VARI process,prepreg resin impregnated fiber fabric under elevated temperature and vacuum pressure.This phenomenon was characterized by fluorescent micrographs with different holding temperature and time.Its influences on processing quality and mechanical performance for co-VARI stiffened skin with different filler materials at triangular region were further analyzed by optical micrographs and pull-off test,respectively.The results show that increasing holding temperature and prolonging holding time can promote prepreg resin impregnation in fiber fabric.Moderate prepreg resin impregnation is favorable to reduce resin rich region and increase fiber volume fraction at prepreg-fabric interface.Moreover,prepreg resin impregnation effect plays significant roles on pull-off performance for co-VARI stiffened skin with fabric filler but has negligible influences on specimens with prepreg filler.In addition,compared with stiffened skin with fabric filler,superior processing quality and pull-off performances are achieved for co-VARI stiffened skin with prepreg core filler.These results are helpful to optimize processing procedures and fabricate composite structure by coVARI process. | MA XuQiang GU YiZhuo LI Min LI YanXia ZHANG ZuoGuang | 2014 | Science China(Technological Sciences)2014，57，10： | 6 |
| 14 | Extraction of hydrogen chloride by a coupled reaction-solvent extraction process显示文摘A coupled 反应溶剂抽取过程被用来把 HCl 从模仿的蒸馏器浪费移开。各种各样的提炼之物和 diluents 的抽取表演被比较,在各种各样的 diluents 的 N235 (第三级的胺的混合物) 的明显的盐基度是坚定的。最好的结果作为提炼之物用 N235 和 isoamyl 酒精被获得并且稀释分别地。从联合抽取的 HCl 的收益与这个抽取系统是 75% 。为在两个的 HCl 的移动的机制直接、联合的抽取被调查。为联合抽取, R 3 NHCl 离子对建筑群涉及 HCl 移动。为直接抽取,机制在 HCl 的高集中包含了氢契约的形成。 | Yunzhao Li Xingfu Song Guilan Chen Shuying Sun Yanxia Xu Jianguo Yu | 2015 | Frontiers of Chemical Science and Engineering2015，9，4： | 6 |
| 15 | Dry Heat Treatment Reduces the Occurrence of Cladosporium cucumerinum, Ascochyta citrullina, and Colletotrichum orbiculare on the Surface and Interior of Cucumber Seeds显示文摘Dry heat treatment has been identifie as a method for disinfecting seed-borne pathogens in vegetable seeds. This study demonstrated that three seed-borne pathogens of cucumber(Cladosporium cucumerinum that causes scabs, Ascochyta citrullina that results in gummy stem blight,and Colletotrichum orbiculare that induces anthracnose) could be effectively eradicated from cucumber seeds by dry heat treatment. In vitro growth of these three pathogens was inhibited by dry heat treatment at 70 °C for 40 min. These pathogens were inactivated after exposing infected seeds to 70 °C dry heat for at least 90 min. Seed infection was significant y reduced by exposing the seeds to 70 °C dry heat for at least 40 min. Seed moisture content and germination were slightly reduced after 70 °C heat treatment for 40–120 min. Seed vigor remained at a high level after dry heat treatment at 70 °C for 90 min. In conclusion, 70 °C dry heat treatment for 90 min was determined to be the optimal method for eradication of C. cucumerinum, Didymella bryoniae, and C. orbiculare from cucumber seeds. | SHI Yanxia MENG Shanshan XIE Xuewen CHAI Ali LI Baoju | 2016 | Horticultural Plant Journal2016，2，1： | 5 |
| 16 | Base editing-mediated splicing correction therapy for spinal muscular atrophy显示文摘Dear Editor,Spinal muscular atrophy(SMA)is a devastating autosomal recessive motor neuron disease.1,2 Infants with more severe forms of type I SMA die before the age of 2 if no intervention is provided.1,2 Spinraza and zolgensma have been approved by the FDA as SMA therapeutics for pediatric patients.1,2 However,as an antisense oligonucleotide(ASO)based therapy,spinraza requires four loading doses,followed by three annual maintenance doses.The patients would be subjected to repeated intrathecal injections in the procedure.Zolgensma is a single-dose gene-replacement therapy for SMA,but unfortunately is unreliable in maintaining a high,stable level of gene expression.These issues have limited the therapeutic effects of the two approved drugs for SMA. | Xiang Lin Haizhu Chen Ying-Qian Lu Shunyan Hong Xinde Hu Yanxia Gao Lu-Lu Lai Jin-Jing Li Zishuai Wang Wenqin Ying Lixiang Ma Ning Wang Erwei Zuo Hui Yang Wan-Jin Chen | 2020 | Cell Research2020，30，6： | 5 |
| 17 | Mixed lineage kinase domain-like protein induces RGC-5 necroptosis following elevated hydrostatic pressure显示文摘 | Lvshuang Liao Lei Shang Na Li Shuchao Wang Mi Wang Yanxia Huang Dan Chen Jufang Huang Kun Xiong | 2017 | Acta Biochimica et Biophysica Sinica2017，49，10： | 5 |
| 18 | Evaluation of oasis stability in the lower reaches of the Tarim River显示文摘Oasis stability in the lower reaches of the Tarim River was assessed at the landscape scale(including changes in landscape pattern and land use in the oasis) and at the regional scale(including the cold-island effect and NDVI of the oasis) based on the methods of landscape ecology,GIS and Remote Sensing(RS).Thematic Mapping(TM) remote sensing images from 1990,2000 and 2009 were employed along with the related meteorological and hydrological data pertaining to the reclamation area of the oasis in the lower reaches of the Tarim River.The results indicated that landscape heterogeneity and oasis complexity increased between 1990 and 2000.The comprehensive index of the degree of land use,the average index of the cold-island effect,NDVI value and oasis stability all decreased.However,the change trends in the indices referred to above were opposite between 2000 and 2009,and oasis stability was enhanced to some extent. | Chao LENG YaNing CHEN XinGong LI YanXia SUN | 2011 | Journal of Arid Land2011，3，2： | 4 |
| 19 | Comparative evaluation of the impact of GRAPES and MM5 meteorology on CMAQ prediction over Pearl River Delta, China显示文摘The community multiscale air quality (CMAQ) model was used to forecast air quality over the Pearl River Delta region from December 2013 to January 2014.The pollution forecasting performance of CMAQ coupled with two different meteorological models,i.e.,the global/regional assimilation and prediction system (GRAPES) and the fifth-generation mesoscale model (MM5),was assessed by comparison with observational data.The effects of meteorological factors and physicochemical processes on the forecast results were discussed through process analysis.The results showed that both models exhibited good performance but that of GRAPES-CMAQ was better.GRAPES was superior in predicting the overall variation tendencies of meteorological fields,but it showed large deviations in atmospheric pressure and wind speed.This contributed to the higher correlation coefficients of the pollutants with GRAPES-CMAQ but with greater deviations.The underestimations of nitrate and ammonium salt contributed to the underestimations of both particulate matter and extinction coefficients.Source emissions made the only positive contributions to surface layer SO2,CO,and NO.It was found that O3 originated primarily from horizontal and vertical transport and that its consumption was predominantly via chemical processes.Conversely,NO2 was found derived primarily from chemical production. | Tao Deng Yiang Chen Qilin Wan Yanxia Zhang Xuejiao Deng Yanyan Huang Guangfeng Dai Fei Li | 2018 | Particuology2018，16，5： | 4 |
| 20 | High detectivity photodetectors based on perovskite nanowires with suppressed surface defects显示文摘Solution-processable,single-crystalline perovskite nanowires are ideal candidates for developing low-cost photodetectors,but their detectivities are limited due to a high level of unintentional defects.Through the surfaceinitiated solution-growth method,we fabricated high-quality,single-crystalline,defects-suppressed MAPbI_(3) nanowires,which possess atomically smooth side surfaces with a surface roughness of 0.27 nm,corresponding to a carrier lifetime of 112.9 ns.By forming ohmic MAPbI_(3)∕Au contacts through the dry contact method,highperformance metal–semiconductor–metal photodetectors have been demonstrated with a record large linear dynamic range of 157 dB along with a record high detectivity of 1.2×10^(14) Jones at an illumination power density of 5.5 nW∕cm^(2).Such superior photodetector performance metrics are attributed to,first,the defects-suppressed property of the as-grown MAPbI_(3) nanowires,which leads to a quite low noise current in the dark,and second,the ohmic contact between MAPbI_(3) and Au interfaces,which gives rise to an improved responsivity compared with the Schottky contact counterpart.The realized high-performance MAPbI_(3) nanowire photodetector advances the development of low-cost photodetectors and has potential applications in weak-signal photodetection. | GUOHUI LI RUI GAO YUE HAN AIPING ZHAI YUCHENG LIU YUE TIAN BINING TIAN YUYING HAO SHENGZHONG LIU YUCHENG WU YANXIA CUI | 2020 | Photonics Research2020，8，12： | 4 |
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