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| 1 | Effect of Alkali Stress on Soluble Sugar, Antioxidant Enzymes and Yield of Oat显示文摘Alkali stress can cause severe crop damage and reduce production. However, physiological processes involved in alkali stress in oat seedlings are not well understood. In this study, physiological responses and yield of oat to alkali stress were studied using the alkali-tolerant oat genotype Vao-9 and the alkali-sensitive oat genotype Baiyan 5. The results were: (i) low concentrations of alkali stress (25 and 50 mmol L-1) significantly reduced the yield and grain weight while increased the oat grain number per spike. A negative correlation between yield and malondialdehyde (MDA) content at the jointing and grain filling stages and positive correlations between yield on one hand and superoxide dismutase (SOD), and peroxidase (POD) activities on the other at the jointing stage were observed. There was a positive correlation between MDA and soluble sugar at the grain filling stage; (ii) soluble sugar content was increased at the jointing and grain filling stages and decreased at the heading stage by alkali stress; (iii) alkali stress increased the SOD activity during the heading and grain filling stages, and increased the POD activity at the heading stage. As compared to the control, the increase of MDA contents in alkali-treated oat was observed, during the jointing, heading and grain filling stages; (iv) under alkali stress, the oat genotype Vao-9 showed higher antioxidant enzyme activity and lower soluble sugar contents during the heading stage, and lower MDA contents than those in the oat genotype Baiyan 5 under alkali stress. The result suggested that the high ROS scavenging capacity and soluble sugar levels might play roles in oat response to alkali stress. | BAI Jian-hui LIU Jing-hui ZHANG Na YANG Jun-heng SA Ru-la WU Lan | 2013 | Journal of Integrative Agriculture2013，12，8： | 12 |
| 2 | Treatment strategies for mass burn casualties显示文摘因为很多严重受伤的病人在一短时间以内被送,背景集体灼伤伤亡总是是对一个医疗队的大挑战。通常,高死亡正在逼近。从牺牲品的成功的治疗获得的经验可能在在武装 conflict.Methods 指导集体伤亡的照顾是有用的在单个批的 35 个灼伤牺牲品,坐飞机不停地被转移并且从一个远省的高速公路,被承认 48 个小时损害以后。所有病人与吝啬的年龄是男性的(22.4 ? 蟠 ?( | CHAI Jia-ke SHENG Zhi-yong YANG Hong-ming HAO Dai-feng SHEN Chuan-an JIA Xiao-ming LI Feng JING Sa LI Li-gen SONG Hui-feng JIA Chi-yu TUO Xiao-ye SUN Tian-jun HU Quan | 2009 | Chinese Medical Journal2009，，5： | 10 |
| 3 | Crucial role of the sarcoplasmic reticulum in the developmental regulation of Ca2+ transients and contraction in cardiomyocytes derived from embryonic stem cells显示文摘 | Fu JD Li J Tweedie D Yu HM Chen L Wang R Riordon DR Brugh SA Wang SQ Boheler KR Yang HT | 2006 | 中国生物学文摘2006，20，7： | 9 |
| 4 | Association between N-terminal proB-type Natriuretic Peptide and Depressive Symptoms in Patients with Acute Myocardial Infarction显示文摘 | Yan Ren Jiao Jia Jian Sa Li-Xia Qiu Yue-Hua Cui Yue-An Zhang Hong Yang Gui-Fen Liu | 2017 | Chinese Medical Journal2017，，5： | 6 |
| 5 | Death and do-not-resuscitate order in the emergency department:A single-center three-year retrospective study in the Chinese mainland显示文摘BACKGROUND:Consenting to do-not-resuscitate(DNR)orders is an important and complex medical decision-making process in the treatment of patients at the end-of-life in emergency departments(EDs).The DNR decision in EDs has not been extensively studied,especially in the Chinese mainland.METHODS:This retrospective chart study of all deceased patients in the ED of a university hospital was conducted from January 2017 to December 2019.The patients with out-of-hospital cardiac arrest were excluded.RESULTS:There were 214 patients’deaths in the ED in the three years.Among them,132 patients were included in this study,whereas 82 with out-of-hospital cardiac arrest were excluded.There were 99(75.0%)patients’deaths after a DNR order medical decision,64(64.6%)patients signed the orders within 24 hours of the ED admission,68(68.7%)patients died within 24 hours after signing it,and 97(98.0%)patients had DNR signed by the family surrogates.Multivariate analysis showed that four independent factors infl uenced the family surrogates’decisions to sign the DNR orders:lack of referral(odds ratio[OR]0.157,95%confi dence interval[CI]0.047–0.529,P=0.003),ED length of stay(ED LOS)≥72 hours(OR 5.889,95%CI 1.290–26.885,P=0.022),acute myocardial infarction(AMI)(OR 0.017,95%CI 0.001–0.279,P=0.004),and tracheal intubation(OR 0.028,95%CI 0.007–0.120,P<0.001).CONCLUSIONS:In the Chinese mainland,the proportion of patients consenting for DNR order is lower than that of developed countries.The decision to sign DNR orders is mainly affected by referral,ED LOS,AMI,and trachea intubation. | Chuan-qi Ding Yu-ping Zhang Yu-wei Wang Min-fei Yang Sa Wang Nian-qi Cui Jing-fen Jin | 2020 | World Journal of Emergency Medicine2020，11，4： | 5 |
| 6 | Lateral Hypothalamic Area Glutamatergic Neurons and Their Projections to the Lateral Habenula Modulate the Anesthetic Potency of Isoflurane in Mice显示文摘The lateral hypothalamic area(LHA)plays a pivotal role in regulating consciousness transition,in which orexinergic neurons,GABAergic neurons,and melanin-concentrating hormone neurons are involved.Glutamatergic neurons have a large population in the LHA,but their anesthesia-related effect has not been explored.Here,we found that genetic ablation of LHA glutamatergic neurons shortened the induction time and prolonged the recovery time of isoflurane anesthesia in mice.In contrast,chemogenetic activation of LHA glutamatergic neurons increased the time to anesthesia and decreased the time to recovery.Optogenetic activation of LHA glutamatergic neurons during the maintenance of anesthesia reduced the burst suppression pattern of the electroencephalogram(EEG)and shifted EEG features to an arousal pattern.Photostimulation of LHA glutamatergic projections to the lateral habenula(LHb)also facilitated the emergence from anesthesia and the transition of anesthesia depth to a lighter level.Collectively,LHA glutamatergic neurons and their projections to the LHb regulate anesthetic potency and EEG features. | Shiyi Zhao Rui Li Huiming Li Sa Wang Xinxin Zhang Dan Wang Juan Guo Huihui Li Ao Li Tingting Tong Haixing Zhong Qianzi Yang Hailong Dong | 2021 | Neuroscience Bulletin2021，37，7： | 5 |
| 7 | Enhancement for φ-OTDR Performance by Using Narrow Linewidth Light Source and Signal Processing显示文摘以便基于阶段敏感的光时间域反射计提高一个分布式的声学的察觉到系统的 signal-to-noise-ratio (我们建议了的 -OTDR), 分割的 unwrapping 算法,阶段差别的平均评价,和过滤方法的无限的推动反应(IIR ) 的联合。信号质量的改进数字地被表明。而且,我们学习了影响在 -OTDR 表演上源于轻来源噪音。结果看了那在 -OTDR 系统使用的轻来源的线宽什么时候更狭窄,系统的表演更好。简言之,当更狭窄的线宽光来源被选择,平均评价阶段差别的方法被使用时,如此的一个 -OTDR 系统能获得高质量的使解调的信号。 | Meng ZHANG Song WANG Yuanwei ZHENG Yao YANG Xingjie SA Li ZHANG | 2016 | Photonic Sensors2016，6，1： | 3 |
| 8 | Identification of the unknown shielding parameters with gammaray spectrum using a derivative-free inverse radiation transport model显示文摘Identifying the unknown geometric and material information of a multi-shield object by analyzing the radiation signature measurements is always an important problem in national and global security. In order to identify the unknown shielding layer thicknesses of a source/shield system with gamma-ray spectra, we have developed a derivative-free inverse radiation transport model based on a differential evolution algorithm with global and local neighbourhoods(IRT-DEGL). In the present paper, the IRT-DEGL model is further extended for estimating the unknown thicknesses with random initial guesses and material mass densities of multi-shielding layers as well as their combinations. Using the detected gamma-ray spectra,the illustration of inverse studies is implemented and the main influence factors for inverse results are also analyzed. | Ying Chen Lian-Ping Zhang Sa Xiao Lun-Qiang Wu Shan-Li Yang Bing-Yuan Xia Jian-Min Hu | 2018 | Nuclear Science and Techniques2018，29，5： | 3 |
| 9 | 基于iTRAQ定量蛋白质组学技术分析日粮中添加非淀粉多糖酶对生长猪背最长肌中蛋白表达影响(英文)显示文摘目的:通过日粮中添加非淀粉多糖酶,运用同位素标记相对和绝对定量技术(i TRAQ技术)分析非淀粉多糖酶对生长猪背最长肌蛋白质表达有何影响,为饲料中添加非淀粉多糖酶提供理论基础。创新点:采用i TRAQ定量蛋白质组学技术,通过对生长猪背最长肌蛋白质表达进行高通量分析,发现日粮中添加非淀粉多糖酶可影响许多功能蛋白表达,从分子水平阐述了其发挥作用的机理。方法:将体重约39 kg生长猪(48头)随机分为两个处理,每个处理4个重复,每个重复6头猪。对照组饲喂基础日粮,试验组在基础日粮中添加0.6%非淀粉多糖酶。50天试验期后,每个重复屠宰1头猪(n=8),取背最长肌,通过i TRAQ定量蛋白质组学技术分析肌肉组织中差异蛋白表达。结论:i TRAQ定量蛋白质组学分析结果显示,试验组与对照组相比,共发现51个差异蛋白,其中38个可进行生物学功能定位(图1,表6)。差异表达蛋白中与能量生成、蛋白质合成、肌肉分化、免疫、抗氧化和解毒相关蛋白表达量上调,而与炎症反应相关蛋白表达量下调。综上所述,生长猪日粮中添加非淀粉多糖酶不仅可改善生产性能,同时还可调节肌肉中诸多代谢功能。 | Ji-ze ZHANG Yang GAO Qing-ping LU Ren-na SA Hong-fu ZHANG | 2015 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2015，16，6： | 2 |
| 10 | Alcohol consumption and cigarette smoking increase the frequency of p53 mutations in non-small cell lung cancer显示文摘 | Ahrendt SA Chow JT Yang SC | 2000 | Cancer Research2000，60，12： | 1 |
| 11 | Experience with the use of high-dose interleukin-2 in the treatment of 65 cancer patients显示文摘 | Rosenberg SA Lotze MT Yang JC | 1999 | Ann Surg1999，210，4： | 1 |
| 12 | Endovaseular treatment strategies for cerebral vasospasm显示文摘 | Mindea SA Yang BP Bendok BR | 2006 | Neurosurg Focus2006，21，3： | 1 |
| 13 | Endovascular treatment strategies for cerebral vasospasm显示文摘 | Yang BP Bendok BR | 2006 | Neurosurg Focus2006，21，： | 1 |
| 14 | Twist,a master regulator ofmorphogenesis,plays an essential role in tumor metastasis 显示文摘 | Yang J Mani SA Donaher JL | 2004 | Cell2004，117，7： | 1 |
| 15 | Successful treatment with tandem consolidation using 90 yttrium-ibritumomab tiuxetan (Zevalin) and high-dose therapy with autologous PBSCT in a patient with relapsed mantle cell lymphoma presenting as multiple lymphomatous polyposis 显示文摘 | Han E J Yang SA Sohn HS | 2012 | Bone Marrow Transplantation2012，47，6： | 1 |
| 16 | Twist,a master regulator of morphogenesis,plays an essential role in tumor metastasis显示文摘 | Yang J Mani SA Donaher JL | | 0，，07： | 1 |
| 17 | Kidney injury molecule-1 :a tissue and urinary biomarker for nephrotoxicant induced renal injury显示文摘 | Ichimura T Hung CC Yang SA | 2004 | Am J Physiol Renal Physiol2004，286，3： | 1 |
| 18 | Effectiveness of thePPARγagonist,GW570,in liver fibrosis显示文摘 | Yang L Stimpson SA Chen L | 2010 | InflammRes2010，59，12： | 1 |
| 19 | Rodent models of Alzheimer's disease rat Abeta infusion approaches to am- yloid deposits 显示文摘 | Frautschy SA Yang F Calderon L | 1996 | Neurobiol Aging1996，17，2： | 1 |
| 20 | Pupil location under mesopic, photopic, and pharmacologically dilated conditions 显示文摘 | Yang Y Thompson K Burns SA | 2002 | Invest Ophthalmol Vis Sci2002，43，7： | 1 |
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