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| 1 | Identification and characterization of neuroblasts in the subventricular zone and rostral migratory stream of the adult human brain显示文摘在成年人的前脑遗体在 subventricular 地区(SVZ ) 和象小径一样的喙的迁移的溪流(RMS ) 的存在在神经发生的成年人的大脑,而是坚持识别新神经原兴趣大高度争论。在现在的学习,我们在成年猴子,胎儿的人和成年人的大脑描述了 RMS 的一般配置。我们提供神经母细胞在成年人的大脑的前面的腹的 SVZ 和 RMS 连续地存在的证据。没有形成链,神经母细胞单身地或在对出现;他们展出迁移的形态学和合作快车不成熟的 neuronal 标记 doublecortin, polysialylated 神经房间粘附分子和 β III 导管素。很少这些神经母细胞看起来活跃地在前面的腹的 SVZ 正在增殖,显示沿着 RMS 散布的神经母细胞是最可能的但是任何一个都没在 RMS 源于腹的 SVZ。有趣地,没有神经母细胞在成年人的嗅觉的灯泡被发现。一起拿,我们的数据建议 SVZ 维持能力在成年人的大脑生产神经母细胞。 | CongminWang FangLiu Ying-YingLiu Cai-HongZhao YanYou LeiWang JingxiaoZhang BinWei TongMa QiangqiangZhang YueZhang RuiChen HongjunSong ZhengangYang | 2011 | Cell Research2011，21，11： | 13 |
| 2 | Effect of acetazolamide on stable carbon isotope fractionation in Chlamydomonas reinhardtii and Chlorella vulgaris显示文摘The effect of extracellular carbonic anhydrase (CAex) on stable carbon isotope fractionation in algae is still unclear. The stable carbon isotope composition and algal growth in the presence and absence of the membrane-impermeable CA inhibitor acetazolamide were compared in Chlamydomonas reinhardtii and Chlorella vulgaris. The CAex of both algal species contributed about 9‰ of the stable carbon isotope fractionation and exhibited a dosage effect. Therefore, evidence in vivo that CAex leads to a larger carbon isotope fractionation of algae is presented. | WU YanYou XU Ying LI HaiTao XING DeKe | 2012 | Chinese Science Bulletin2012，57，7： | 10 |
| 3 | MiR-29a/b/c regulate human circadian gene hPER1 expression by targeting its 3/UTR显示文摘在哺乳动物的几必要生物进步被生理节奏的节奏调整。不过分子的机制 ofoscillating 这些生理节奏的节奏被揭开了,生理节奏的基因的特定的功能不是很, clear.It 被报导了那由 microRNA 将生理节奏的基因击倒是有用策略探索 circadianrhythms 的功能。在这研究,通过屏蔽途径的前面的生物信息学,我们作为有势力 inhibitorsfor 识别了 miR-29a/b/c 人的生理节奏的基因 hPER1。我们进一步发现 miR-29a/b/c 能直接在人的 A549 房间在 mRNA 和蛋白质表示层次指向 hPER1 3untranslated 区域(UTR ) 和下面调整 hPER1。因此,我们的调查结果建议 hPER1 的表示被 miR-29a/b/c 调整,它可以也为 hPER1 的功能提供新线索。 | Xiyan Zhao Xueqiang Zhu Shuting Cheng Yizhou Xie Zhengrong Wang Yanyou Liu Zhou Jiang Jing Xiao Huiling Guo Yuhui Wang | 2014 | Acta Biochimica et Biophysica Sinica2014，46，4： | 7 |
| 4 | Quantification of photosynthetic inorganic carbon utilisation via a bidirectional stable carbon isotope tracer显示文摘The amount of bicarbonate utilised by plants is usually ignored because of limited measurement methods.Accordingly, this study quantified the photosynthetic assimilation of inorganic carbon(CO_2and HCO_3^-) by plants. The net photosynthetic CO_2assimilation(PN), the photosynthetic assimilation of CO_2 and bicarbonate(PN'),the proportion of increased leaf area(fLA) and the stable carbon isotope composition(δ^(13)C) of Orychophragmus violaceus(Ov) and Brassica juncea(Bj)under three bicarbonate levels(5, 10 and 15 mm NaHCO_3)were examined to determine the relationship among PN,PN' and fLA. PN', not PN,changed synchronously with fLA.Moreover, the proportions of exogenous bicarbonate and total bicarbonate(including exogenous bicarbonate and dissolved CO_2-generated bicarbonate) utilised by Ov were 2.27 % and 5.28 % at 5 mm bicarbonate, 7.06 % and13.28 % at 10 mm bicarbonate, and 8.55 % and 17.31 % at15 mm bicarbonate, respectively. Meanwhile, the proportions of exogenous bicarbonate and total bicarbonate utilised by Bj were 1.77 % and 3.28 % at 5 mm bicarbonate,2.11 % and 3.10 % at 10 mm bicarbonate, and 2.36 % and3.09 % at 15 mm bicarbonate, respectively. Therefore, the dissolved CO_2-generated bicarbonate and exogenous bicarbonate are important sources of inorganic carbon for plants. | Hongtao Hang Yanyou WU | 2016 | Acta Geochimica2016，35，2： | 6 |
| 5 | Empowering fall webworm surveillance with mobile phone-based community monitoring: a case study in northern China显示文摘Recent advances in information and communication technologies, such as mobile Internet and smartphones, have created new paradigms for participatory environment monitoring. The ubiquitous mobile phones with capabilities such as a global positioning system,camera, and network access, offer opportunities to establish distributed monitoring networks that can perform a wide range of measurements for a landscape. This study examined the potential of mobile phone-based community monitoring of fall webworm(Hyphantria cunea Drury).We built a prototype of a participatory fall webworm monitoring system based on mobile devices that streamlined data collection, transmission, and visualization. We also assessed the accuracy and reliability of the data collected by the local community. The system performance was evaluated at the Ziya commune of Tianjin municipality in northern China, where fall webworm infestation has occurred. The local community provided data with accuracy comparable to expert measurements(Willmott's index of agreement>0.85). Measurements by the local community effectively complemented remote sensing images in both temporal and spatial resolution. | Chengbo Wang Yanyou Qiao Honggan Wu Yuanfei Chang Muyao Shi | 2016 | Journal of Forestry Research2016，27，6： | 4 |
| 6 | Effects of carbon anhydrase on utilization of bicarbonate in microalgae:a case study in Lake Hongfeng显示文摘A bidirectional labeling method was established to distinguish the proportions of HCO_3^- and CO_2 utilization pathways of microalgae in Lake Hongfeng. The method was based on microalgae cultured in a medium by adding equal concentrations of NaH^(13)CO_3 with different δ^(13)C values simultaneously. The inorganic carbon sources were quantified according to the stable carbon isotope composition in the treated microalgae. The effects of extracellular carbonic anhydrase(CAex) on the HCO^-_3 and CO_2 utilization pathways were distinguished using acetazolamide, a potent membrane-impermeable carbonic anhydrase inhibitor. The results show utilization of the added HCO^-_3 was only 8% of the total carbon sources in karst lake. The proportion of the HCO^-_3 utilization pathway was 52% of total inorganic carbon assimilation. Therefore, in the natural water of the karst area, the microalgae used less bicarbonate that preexisted in the aqueous medium than CO_2 derived from the atmosphere. CAex increased the utilization of inorganic carbon from the atmosphere. The microalgae with CAex had greater carbon sequestration capacity in this karst area. | Haitao Li Yanyou Wu Lihua Zhao | 2018 | Acta Geochimica2018，37，4： | 4 |
| 7 | Effect of Zn deficiency and excessive bicarbonate on the allocation and exudation of organic acids in two Moraceae plants显示文摘The effect of zinc(Zn) deficiency and excessive bicarbonate on the allocation and exudation of organic acids in plant organs(root, stem, and leaf) and root exudates of two Moraceae plants(Broussonetia papyrifera and Morus alba) were investigated. Two Moraceae plants were hydroponically grown and cultured in nutrient solution in four different treatments with 0.02 mM Zn or no Zn,combined with no or 10 mM bicarbonate. The variations of organic acids in different plant organs were similar to those of root exudates in the four treatments except B. papyrifera, which was in a treatment that was a combination of 0.02 mM Zn and no bicarbonate. The response characteristics in the production, translocation, and allocation of organic acids in the plant organs and root exudates varied with species and treatments. Organic acids in plant organs and root exudates increased under Zn-deficient conditions,excessive bicarbonate, or both. An increase of organic acids in the leaves resulted in an increase of root-exuded organic acids. B. papyrifera translocated more oxalate and citrate from the roots to the rhizosphere than M. alba under the dual influence of 10 mM bicarbonate and Zn deficiency. Organic acids of leaves may be derived from dark respiration and photorespiration. By comparison, organic acids in stems, roots, and root exudates may be derived from dark respiration and organic acid translocation from the leaves. These results provide evidence for the selective adaptation of plants to environments with low Zn levels or high bicarbonate levels such as a karst ecosystem. | Kuan Zhao Yanyou Wu | 2018 | Acta Geochimica2018，37，1： | 2 |
| 8 | Does bicarbonate affect the nitrate utilization and photosynthesis of Orychophragmus violaceus?显示文摘The effect of bicarbonate(HCO_3^-) on the growth and development of plants varies by species. To better understand inorganic carbon and nitrogen assimilation changes of karst-adaptable plants under different HCO_3^- treatments, we conducted experiments on seedlings and in vitro plantlets of Orychophragmus violaceus(Ov).We found that the vital photosynthesis potential(as measured by net photosynthetic rate, actual photochemical efficiency of photosystem-II, photochemical quenching coefficient, and the instantaneous carbon isotope ratio of3-phosphoglycerate) was consistent under different HCO_3^- treatments of Ov. Bicarbonate's lack of effect on carbon assimilation of Ov may be related to carbonic anhydrase in Ov converting HCO_3^- to H2 O and CO2. In this way, Ov could prevent HCO_3^- ion toxicity and high pH from harming its growth and development under HCO_3^- stress.This study also found that high HCO_3^- concentrations could promote nitrogen assimilation and utilization of Ov through changes in related indexes(foliar nitrogen isotope fractionation ratio, stable nitrogen isotope assimilation ratio, foliar stable nitrogen isotope fractionation, nitrate nitrogen utilization efficiency, and nitrate utilization share)under different HCO_3^- treatments. Bicarbonate has different effects on photosynthesis and on inorganic nitrogen assimilation of Ov, which may be connected tophotosynthesis providing electrons for nitrate/nitrite reduction through the photosynthetic chain. | Ye Lu Yanyou Wu Kaiyan Zhang | 2018 | Acta Geochimica2018，37，6： | 2 |
| 9 | Bicarbonate use and carbon dioxide concentrating mechanisms in photosynthetic organisms显示文摘Photosynthesis is crucial to the reduction of carbon dioxide in the atmosphere.The key enzyme of photosynthesis,Ribulose-1,5-bisphosphate carboxylase/oxygenase(Rubisco),has two mutably competing substrates,CO2 and O2.It has features of carboxylase and oxygenase.Rubisco performs the function of carboxylase to reduce inorganic carbon to form organic substances,which precondition is that more carbon dioxide accumulates around it.Carbon dioxide concentrating mechanisms(CCMs)are vital to cope with the limit of carbon dioxide.Various bicarbonate use pathway has a differential contribution to inorganic carbon assimilation.Bicarbonate transport,extracellular bicarbonate dehydration,or H+-ATPase-driven bicarbonate uptake,which induced CCMs,can support a considerable share of photosynthesis in photosynthetic organisms.However,CCMs in thylakoid membranes may be the most important.The CCMs occurred in the plasma membrane were secondary,evolutionary,and inducible,while CCMs coupled with photosynthetic oxygen evolution in thylakoid membranes,were primitive,major,and indispensable.A hypothetical schematic model of CCMs occurred in the plasma membrane and thylakoid membranes being proposed. | Yanyou Wu | 2021 | Acta Geochimica2021，40，5： | 2 |
| 10 | Photosynthetic capability and Fe, Mn, Cu, and Zn contents in two Moraceae species under different phosphorus levels显示文摘The strong adaptability of Broussonetia papyrifera(L.) Vent. to low phosphorus(P) conditions can be attributed to the large amount of root-exuded organic acids and the high ef?ciency of P extraction. However,microelement contents are in?uenced by low-P stress, and their effects on the photosynthetic capability of B. papyrifera remain unknown. In this study, we investigated the effects of low-P treatment on net photosynthetic rate(P_N);chlorophyll a ?uorescence(ChlF) characteristics; and Fe,Mn, Cu, and Zn contents of B. papyrifera and Morus alba L. seedlings. Results show that B. papyrifera exhibited better photosynthetic capability under moderate P de?-ciency(0.125, 0.063, and 0.031 mmol/L P treatments),whereas the photosynthetic capability of M. alba decreased under moderate and severe P de?ciency(0.016 and0 mmol/L P treatments). Under moderate P de?ciency, the decrease in Cu and Zn contents in B. papyrifera was lower than that in M. alba. Under severe P de?ciency, a considerable decrease of photosynthetic capability in B. papyrifera and M. alba was associated with low Cu and Zn contents. The P N of the two Moraceae species exhibited a better correlation with Cu and Zn contents than with Fe or Mn content. P de?ciency could not only decrease cyclic photophorylation and photosynthetic ef?ciency, but could also affect the stability of thylakoid membrane structure and electron transport ef?ciency by in?uencing the contents of Cu or Zn, thereby affecting photosynthesis. | Deke Xing Yanyou Wu Rui Yu Yansheng Wu Chuan Zhang Zheng Liang | 2016 | Acta Geochimica2016，35，3： | 2 |
| 11 | Beneficial effects of exercise and its molecular mechanisms on depression in rats显示文摘 | Hang Zheng Yanyou Liu Wei Li | 2006 | Behavioural Brain Research2006，168，： | 1 |
| 12 | The influence of three mangrove species on the distribution of inorganic nitrogen and phosphorus in the Quanzhou Bay estuarine wetland soils显示文摘This study aims to investigate the effects of region and three regional dominated mangrove species(Avicennia marina, Aegiceras corniculatum and Kandelia candel) on the distribution of inorganic nitrogen and phosphorus. Measurement of the inorganic nitrogen and phosphorus and enzymatic activities was carried out in soils covered by three mangrove species in the Quanzhou Bay estuarine wetlands, a typical coastal wetland in China.Species with a higher biomass in upstream and midstream absorb more nitrogen from soils, and the retention of the available phosphorus in the soils of different regions causes the regional variation of phosphorus. In areas dominated by A. marina, nitrate nitrogen is lower while available phosphorus is higher. Meanwhile, nitrate nitrogen and available phosphorus are higher in the soils covered by K. candel.Moreover, all three species affect the elemental and enzymic stoichiometry. The mangrove species influences the diversity of the elemental and enzymic stoichiometric relationship through differential microenvironments, which induce the biodiversity of wetland ecosystems. Thus, this study may facilitate a better understanding of the transformation ability of mangroves to nitrogen and phosphorus and will therefore be beneficial for providing a basis for the ecological restoration of estuarine wetlands. | Guiyao Zhou Yanyou Wu Deke Xing Mingming Zhang Rui Yu Weiyi Qiao Qaiser Javed | 2016 | Acta Geochimica2016，35，1： | 1 |
| 13 | Study on photosynthetic characteristics of Orychophragmus violaceus related to shade-tolerance显示文摘 | Yanyou Wu Pingping Li Yuguo Zhao Jizhan Wang Xiangming Wu | 2007 | Scientia Horticulturae2007，，2： | 1 |
| 14 | Comparison of carbonic anhydrase activity among various species of plantlets显示文摘 | Wu Yanyou Li Xiteng Li Pingping | 2006 | Plant Cell Tissue and Organ Culture2006，84，1： | 1 |
| 15 | Combined effect of bicarbonate and water in photosynthetic oxygen evolution and carbon neutrality显示文摘Carbon neutrality is widely concerned and highly valued by many countries.Biosphere has always maintained the balance between oxidized organic substances and assimilated organic matter,resulting in netzero carbon dioxide(CO_(2)) emissions and maintaining its own carbon neutrality.Nature has set a good example for human beings to coordinate oxygen(O_(2)) balance and CO_(2)balance,and achieve carbon neutrality.How does photosynthetic oxygen evolution initiate carbon and water neutrality?My synthesis shows that photo system Ⅱ functions as carbonic anhydrase to catalyze the reaction of CO_(2)hydration under physiological conditions,and CO_(2)hydration coupled with chemical equilibrium,H^(+)+HCO_(3)^(-)→1/2O_(2)+2e^(-)+2H^(+)+CO_(2),occurs in a photosystem Ⅱ corecomplex.Meanwhile,I focused on the revisiting of four classical heavy oxygen(O^(18)) labeling experiments and found that bicarbonate can promote photo synthetic oxygen evolution,and that photo synthetic oxygen evolution can alternately come from bicarbonate and water,not only water.Bicarbonate photolysis and water photolysis account for half of the photo synthetic oxygen evolution respectively,which can well explain the bicarbonate effect,Dole effect and plants’ environmental adaptability.Photosynthetic oxygen evolution initiated the journey of water metabolism and carbon metabolism in nature,which led to the coupling as 1:1(mol/mol) stoichiometric relationship between the reduction of CO_(2)and oxidation of organic carbon,coordinated the evolution of the atmosphere,hydrosphere,lithosphere and biosphere,and realized 'carbon neutrality' in the whole Earth system. | Yanyou Wu | 2023 | Acta Geochimica2023，42，1： | 1 |
| 16 | Deoxyribozymes inhibit the expression of periodl gene in vitro显示文摘To investigate the effect of two deoxyribozymes targeting period1 (per1) mRNA in vitro for exploring a novel gene therapy approach about circadian rhythm diseases, the specific deoxyribozymes targeting per1 were designed and synthesized chemically following MFold analysis according to its mRNA secondary structure. per1 RNA fragments were prepared by in vitro transcription of pcDNA3.1(+)-per1164:256. The cleavage reactions containing deoxyribozymes and per1 RNA fragments were performed under certain conditions. With the transfection tech- nique mediated by LipofectAMINETM, pcDNA3-per1 and DRz164 or DRz256 were introduced into NIH3T3 cells. The effects of deoxyribozymes on per1 were studied by reverse tran- script-polymerase chain reaction (RT-PCR) and flow cytometry (FCM). When deoxyribozymes and RNA transcripts were incubated under the adopted conditions at 37℃ for 2 h, about 63% of per1164:256 RNA transcripts were cleaved by DRz164 and about 50.5% by DRz256. After co- transfecting pcDNA3-per1 with DRz164 or DRz256, the expression of per1 mRNA was de- creased, as indicated by RT-PCR semi-quantity analysis. FCM analysis showed that Per1 protein was inhibited. Both DRz164 and DRz256 targeting per1 have the specific cleavage activity to- ward per1 mRNA in vitro and can highly block the expression of per1 gene in cellular milieu. | ZHOU Wei WANG Yueqi LIU Yanyou PENG Wenzhen XIAO Jing ZHU Bin WANG Zhengrong | 2005 | Science China(Life Sciences)2005，48，3： | 1 |
| 17 | The role of mPer1 in morphine dependence in mice显示文摘 | LIU Yanyou WANG Yueqi WAN Chaoming | 2005 | Neuroscience2005，130，2： | 1 |
| 18 | Circadian effects on outcome following surgery for intracerebral hemorrhage in humans?显示文摘 | Junwen Guan Yuanlin Ding Yanyu Liu Yonghong Li Yanyou Liu Zhengrong Wang | 2008 | Brain Research2008，，： | 1 |
| 19 | Beneficial effects of exercise and its molecular mechanisms on depression in rats显示文摘 | Hang Zheng Yanyou Liu Wei Li | 2006 | Behavioural Brain Research2006，168，： | 1 |
| 20 | Time structure of locomotor activity in mice kept on different light-dark cycles显示文摘 | YangBo Liu Yanyou Wang Yuhui Wang | 2007 | Bi- ological Rhythm Research2007，38，6： | 1 |
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