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| 1 | Vascular endothelial growth factor receptor 2(VEGFR-2) plays a key role in vasculogenic mimicry formation,neovascularization and tumor initiation by Glioma stem-like cells显示文摘Human glioblastomas(GBM)are thought to be initiated by glioma stem-like cells(GSLCs).GSLCs also participate in tumor neovascularization by transdifferentiating into vascular endothelial cells.Here,we report a critical role of GSLCs in the formation of vasculogenic mimicry(VM),which defines channels lined by tumor cells to supply nutrients to early growing tumors and | Yao X Ping Y Liu Y Chen K Yoshimura T Liu M Gong W Chen C Niu Q Guo D Zhang X Wang JM Bian X | 2013 | 中国神经肿瘤杂志2013，11，3： | 23 |
| 2 | TRPS1是一种高度敏感和特异的乳腺癌标志物,尤其对三阴性乳腺癌显示文摘基于雌激素受体(ER)/孕激素受体(PR)及人类表皮生长因子受体2(HER2)表达,乳腺癌分为ER阳性、PR阳性、HER2阳性(15%)及三阴性(TNBC,15%)。ER阳性及PR阳性分别被称为管腔A型及管腔B型,二者约占乳腺癌的70%。TNBC具有未分化表型,通常与基底样乳腺癌重叠,复发率高,转移早,缺乏乳腺起源的肿瘤标志物。 | Ai D Yao J Yang F 方三高(译) 魏建国(校) | 2021 | 诊断病理学杂志2021，28，5： | 7 |
| 3 | Microbial biomass, N mineralization and nitrification, enzyme activities, and microbial community diversity in tea orchard soils显示文摘 | Xue D Yao HY Huang CY | 2007 | 中国生物学文摘2007，21，8： | 6 |
| 4 | A New Species of the Extinct Genus Schizolepis from the Jurassic Daohugou Flora,Inner Mongolia,China with Special Reference to the Fossil Diversity and Evolutionary Implications显示文摘Schizolepis daohugouensis sp。nov。从 Daohugou 植物群的侏罗记沉积被描述,从 Ningcheng 县,内部蒙古自治区域,中国。女锥是苗条的,在形状圆柱,种子规模建筑群泛泛地并且螺旋状地在 35 公里的间隔在锥轴上被安排。种子规模是 bilobed 并且几乎与底分开;规模没有明显的叶柄但是在到锥轴的附件的区域的一个连接。种子规模的每片脑叶在形状是卵形的,在更低的中间的部分最宽;脑叶钝地与全部边缘被削尖。苞规模是塑造的扇子。基于 Schizolepis 的记录,这是有在侏罗记存款一起保存的种子规模, winged 种子和植物的分支的 Schizolepis 的女锥的出现的第一份报告。新发现提供证实 Schizolepis 的种系发生的位置到现存松科的证据。 | ZHANG Jianwei Ashalata D'ROZARIO YAO Jianxin WU Zhenjie WANG Lijun | 2011 | Acta Geologica Sinica(English Edition)2011，85，2： | 6 |
| 5 | Long-term safety of lamivudine treatment in patients with chronic hepatitis B显示文摘 | Anna S.F Lok Ching-Lung Lai Nancy Leung Guang-Bi Yao Zhen-Yu Cui Eugene R Schiff Jules L Dienstag E.Jenny Heathcote Nancy R Little Dorothea A Griffiths Stephen D Gardner Mary Castiglia | 2003 | Gastroenterology2003，，6： | 3 |
| 6 | A new species of the extinct genus Austrohamia (Cupressaceae s.l.) in the Daohugou Jurassic flora of China and its phytogeographical implications显示文摘提炼一棵新针叶树, Austrohamia acanthobractea, sp。nov,从侏罗记 Daohugou 植物群被描述,内部蒙古自治区域,中国。材料由保存得很好的叶状的枝条和分支代表象一样的印象组成排卵锥。有分叉的至少二份订单的叶状的射击;有螺旋状地安排的叶子的最终的 branchlets 替换物或亚反面,在有远侧的圆尖端的底下延;dorsiventrally 变平并且 univeined。Ovuliferous 锥椭圆,不到 1 厘米长,严重地在最终、倒数第二的分支上适用,有在他们的近轴的表面上处理的小卵的螺旋状地安排的苞镇静。存在类似不相同的 taxa,在 Pangaea 在太平洋的双方上显示在东亚(欧亚大陆) 和南美洲之间的原始 Cupressaceae 的大都会的分发。 | Jian-Wei ZHANG Ashalata D'ROZARIO Li-Jun WANG Ya LI Jian-Xin YAO | 2012 | Journal of Systematics and Evolution2012，50，1： | 3 |
| 7 | Surface characterization of steel/steel contact lubricated by PA06 with novel black phosphorus nanocomposites显示文摘In the present work,two types of novel nano additives,titanium sulfonate ligand/black phosphorus(TiLi/BP)and titanium dioxide/black phosphorus(TiCVBP)nanocomposites,were prepared.The tribological behavior of the steel/steel friction pairs lubricated by polyalphaolefins type 6(PA06)containing the nanocomposites under boundary lubrication was studied.The worn surfaces were analyzed using modem surface techniques.The experimental results show that the rubbed surfaces became smooth and showed little wear with the addition of the nanocomposites.TiO_(2)/BP nanocomposites can significantly improve the lubricity of BP nanosheets under high contact stress.The synergistic roles of the load-bearing abilities and rolling effect of TiO_(2) nanoparticles,the slip induced by the BP with its layered structure,and the establishment of a tribofilm on the sliding interface are the basis of the tribological mechanisms. | Zhiheng LUO Jingyuan YU Yufu XU He XI Gang CHENG Lulu YAO Ruhong SONG Karl D DEARN | 2021 | Friction2021，9，4： | 2 |
| 8 | Long-term safety of lamivudine treatment in patients with chronic hepatitis B显示文摘 | Anna S.F Lok Ching-Lung Lai Nancy Leung Guang-Bi Yao Zhen-Yu Cui Eugene R Schiff Jules L Dienstag E.Jenny Heathcote Nancy R Little Dorothea A Griffiths Stephen D Gardner Mary Castiglia | 2003 | Gastroenterology2003，，6： | 2 |
| 9 | Impact of virus genotype on interferon treatment of patients with chronic hepatitis C: a multicenter controlled study显示文摘BACKGROUND: Some factors have been reported to besassociated with a greater likelihood of sustained viral re-sponse ( SVR) in the interferon (IFN) treatment of chronichepatitis C. The factors include HCV genotype, HCVRNA level in serum, state of liver disease, baseline bodyweight, age, sex, and race. The aim of this trial was to in-vestigate the influence of HCV genotype on the IFN treat-ment of patients with chronic hepatitis C.METHODS: The genotypes of HCV virus were determinedin the patients with chronic hepatitis C from several hospi-tals of China enrolled into the randomized, opened andcontrolled trial of Peg-IFN alpha-2a (pegasys) treatment,controlled with IFN-α-2a (roferon-A). The serum ALTlevels and HCV RNA concentrations of the patients weredetected before and at the end of treatment and during thefollow-up. The influence of HCV genotype on the IFNtreatment of patients with chronic hepatitis C was analyzedin intention-to-treat (ITT) population.RESULTS: The HCV genotypes of 202 patients were deter-mined. Of these patients, 158(78.22%) were infected withgenotype 1 HCV and 44(21.78%) with genotype non-1.The viral response at the end of treatment (ETVR) andsustained viral response (SVR) rates were 53.80% and25.32% respectively in patients with genotype 1 HCV, butthey were 61.36% and 43.18% in patients with genotypenon-1. The difference of SVR between patients with geno-type 1 HCV and those with genotype non-1 was significant(P =0.021). After being grouped by the used drugs, theETVR rates of patients infected with genotype 1 and non-1HCV were 76.83% and 80.95% in the patients treated withpegasys (P =0.686); but their SVR rates were 35.37% and66.67% (P =0. 01). The viral relapse rate of genotype 1HCV (55.56%) was significantly higher than that of geno-type non-1 HCV (23.53%) (P=0.02). In roferon-A group,the ETVR and SVR rates of patients with genotype 1 HCVwere 28.95% and 14.47% respectively, which were lowerbut not more significant than those of patients with geno-type non-1 HCV (43.48% and 21.74%). Moreover, the vi-ral relapse rate of genotype 1 HCV (72.73%) was higherbut not more significant than that of genotype non-1 HCV(50.00%) (P=0.21).CONCLUSION: HCV genotype could affect the efficacies,mainly sustained responses, of IFN treatment in patientswith chronic hepatitis C, and the effects of IFN are relatedto drugs and therapeutic course. | Yao Xie, Dao-Zhen Xu, Zhi-Meng Lu, Kang-Xian Luo, Ji-Dong Jia, Yu-Ming Wang,Gui-Zhen Zhao, Shu-Lin Zhang and Da-Zhi Zhang Department of Infeetious Diseases , Beijing Ditan Hos-pital, Beijing 100011 , China Department of Infec-tious Diseases, Ruijin Hospital, Shanghai 200025, China De-partment of Infectious Diseases, Naifang Hospital, First Military Medical U-niversity, Guangzhou 510515, China (Luo KX) Center of Liver Disease,Beijing Friendship Hospital, Beijing 100050, China (Jia J D ) Institute ofInfectious Disease, Southwest Hospital, Third Military Medical University,Chongqing 410032, China Department of Infectious Disea-ses, Second Hospital, China Medical University, Shenyang 110004, China Department of Infectious Diseases, First Hospital, Xi’ an Jiao-tong University, Xi’ an 710061 , China ) Liver Disease Centerof Chongqing, Second Hospital, Chongqing Medical University,Chongqing 410010, China | 2004 | Hepatobiliary & Pancreatic Diseases International2004，3，3： | 2 |
| 10 | A unique deubiquitinase that deconjugates phosphoribosyl-linked protein ubiquitination显示文摘Ubiquitination 调整主人免疫的许多方面并且因此是为传染代理人的一个普通目标。最近的研究表明了细菌的病原体 Legionella pneumophila 的方面受动器家庭的成员攻击不要求主人 ubiquitination 机械的 E1 和 E2 酶的新奇 ubiquitination 机制与 endoplasmic 蜂窝胃联系的几小 GTPases。在这种情况中, ubiquitin 被一项 mono-ADP-ribosyltransferase 活动被 ADP-ribosylation 首先在 Arg 42 激活;中介然后被也住在 SdeA 以内的一项 phosphodiesterase 活动劈开,有到经由一个 phosphoribosyl 连接器的底层蛋白质的丝氨酸残余的 ubiquitin 的附件的伴随物。这里,我们证明方面的效果被 SidJ 反对,一个受动器由位于为方面家庭(SdeC, SdeB 和 SdeA ) 的三个成员编码的地点的基因编码了。SidJ 由劈开连接 phosphoribosylated ubiquitin 到蛋白质底层的 phosphodiester 契约颠倒修改方面的底层的 ubiquitination。SidJ 也显示古典 deubiquitinase 活动但是不要求催化半胱氨酸残余。进一步, SidJ 的这些 deubiquitinase 活动为它在 L 的角色是必要的。pneumophila 感染。最后, SidJ 的活动为高效地在细菌的举起以后在一些小时以内在感染的房间减少许多 ubiquitinated Rab33b 被要求。我们的结果作为工作在方面受动器的活动强加时间的规定的 ubiquitin-deconjugating 酶建立 SidJ。SidJ 可能在表明串联的未来研究是重要的由这唯一的 ubiquitination 调停了,潜在地也在真核细胞的房间调整细胞的过程的。 | Jiazhang Qiu Kaiwen Yu Xiaowen Fei Yao Liu Emesto S Nakayasu Paul D Piehowski Jared B Shaw Kedar Puva Chittaranjan Das Xiaoyun Liu Zhao-Qing Luo | 2017 | Cell Research2017，27，7： | 2 |
| 11 | Ocular resurfacing and alloepithelial rejection in a murine keratoepithelioplasty model显示文摘 | Yao YF Inoue Y Miyazaki D | 1995 | Invest Ophthalmol Vis Sci1995，36，13： | 2 |
| 12 | Equilibria,kinetics,and mechanism in the bicarbonate activation of hydrogen peroxide: oxidation of sulfides by peroxymonocarbonate显示文摘 | RICHARDSON D E YAO H FRANK K M | 2000 | J Am Chem Soc2000，122，： | 1 |
| 13 | Effect of interleukin-10 on gene expression of osteoclastogenic regulatory molecules in the rat dental follicle 显示文摘 | Liu D Yao S Wise GE | 2006 | Eur J Oral Sci2006，114，1： | 1 |
| 14 | Preparation and characterization of gelatin gel with a gradient structure 显示文摘 | Wang Y L Cheng G X Yao K D | 2000 | Polymer Int2000，49，12： | 1 |
| 15 | Application of Lade's criterion to Cam-Clay model显示文摘 | YAO Y P SUN D A | 2000 | Journal of Engineering Mechanics ASCE2000，126，1： | 1 |
| 16 | A new location-inventory policy with reverse logistics applied to B2C e-markets of China显示文摘 | Wang Z Yao D Q Huang P | 2007 | International Journal of Production Econom- ics2007，107，2： | 1 |
| 17 | Analyses of the genetic diversity of matsutake isolates collected from different ecological environments in Asia显示文摘 | Bao D Koike A Yao F | 2007 | Journal of Wood Science2007，53，4： | 1 |
| 18 | The molecular basis for impaired hypoxia-induced VEGF expression in diabetic tissues显示文摘 | Thangarajah H Yao D Chang EI | 2009 | Proc Natl Acad Sci U S A2009，106，13： | 1 |
| 19 | Underwater Target Classification Using Wavelet Packets and Nerual Networks显示文摘 | Azimi-Sadjadi M R Yao D Huang Q | 2000 | IEEE Trans on Neural Network2000，11，3： | 1 |
| 20 | Deterministic multiuser carrier-frequency offset estimation for interleaved OFDMA uplink显示文摘 | Z Cao U Tureli Y D Yao | 2004 | IEEE Trans Commun2004，52，9： | 1 |
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