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| 1 | Air pollutants contribution and control strategies of energy-use related sources in Beijing显示文摘Based on the statistical analysis of emission inventory and ISCST3 model simulation, the emission and ambient concentration contributions of energy-use related sources to the major pollutants of SO2, NOx and PM10 in urban areas of Beijing were analyzed. The SO2 emission contributions of coal burning in power plants, industrial and heating sectors were 49%, 26% and 24% respectively. The vehicle exhaust contributed 74% of the NOx concentration. As to PM10, the industrial sector was the largest emission (28%) and concentration (21%) contributor despite of the fugitive sources. The source emission contributions of VOC and NH3, which greatly influence the generation of secondary pollutants, were discussed as well. This paper also analyzed the control strategies of energy consumption and vehicle sources, based on which the control scenario in 2008 was established and the change of emission and concentration contribution were estimated. The results show that the cleaner energy use, industrial structure improvement, transportation mode modification and single vehicle emission control will greatly improve air quality. The industrial sector will change to the largest contributor of SO2 and as to NOx, vehicle emission control is still important. | HAO Jiming WANG Litao LI Lin HU Jingnan YU Xuechun | 2005 | Science China Earth Sciences2005，48，z2： | 24 |
| 2 | Status and development of high-power laser facilities at the NLHPLP显示文摘In this paper, we review the status of the multifunctional experimental platform at the National Laboratory of High Power Laser and Physics(NLHPLP). The platform, including the SG-II laser facility, SG-II 9th beam, SG-II upgrade(SG-II UP) facility, and SG-II 5 PW facility, is operational and available for interested scientists studying inertial confinement fusion(ICF) and a broad range of high-energy-density physics. These facilities can provide important experimental capabilities by combining different pulse widths of nanosecond, picosecond, and femtosecond scales. In addition, the SG-II UP facility, consisting of a single petawatt system and an eight-beam nanosecond system, is introduced including several laser technologies that have been developed to ensure the performance of the facility. Recent developments of the SG-II 5 PW facility are also presented. | Jianqiang Zhu Jian Zhu Xuechun Li Baoqiang Zhu Weixin Ma Xingqiang Lu Wei Fan Zhigang Liu Shenlei Zhou Guang Xu Guowen Zhang Xinglong Xie Lin Yang Jiangfeng Wang Xiaoping Ouyang Li Wang Dawei Li Pengqian Yang Quantang Fan Mingying Sun Chong Liu Dean Liu Yanli Zhang Hua Tao Meizhi Sun Ping Zhu Bingyan Wang Zhaoyang Jiao Lei Ren Daizhong Liu Xiang Jiao Hongbiao Huang Zunqi Lin | 2018 | High Power Laser Science and Engineering2018，6，4： | 8 |
| 3 | Changes in the spatial scale of Beijing UHI and urban development显示文摘The seasonal and interannual variations of Beijing urban heat island (UHI) are investigated in this paper using the temperature data from 1960 to 2000 at 20 meteorological stations in the Beijing region, and then the relationship between the intensity and spatial scale of UHI and Beijing urbanization indices is analyzed and discussed. Main conclusions are the followings. First, Beijing UHI shows obvious seasonal variations, and it is strongest in winter, next in spring and autumn, and least in summer. The seasonal variation of the UHI mainly occurs in the urban area. The UHI intensity at the center of Beijing is more than 0.8℃ in winter, and only 0.5℃ in summer. Second, the intensity of Beijing HUI exhibits a clear interannual warming trend with its mean growth rate (MGR) being 0.3088℃/10 a. The MGR of HUI is largest in winter, next in spring and autumn, and least in summer, and the urban temperature increase makes a major contribution to the growth of HUI intensity. Third, since the Reform and Opening, the urbanization indices have grown several ten times or even one hundred times, the intensity of HUI has increased dramatically, and its spatial scale also expanded distinctively along with the expansion of urban architectural complexes. Fourth, the interannual variation of urbanization indices is very similar with that of HUI intensity, and their linear correlation coefficients are significant at a more than 0.001 confidence level. | YU Shuqiu, BIAN Lingen & LIN Xuechun State Key Laboratory on Severe Weather, Chinese Academy of Meteorological Sciences, Beijing 100081, China National Climate Center, China Meteorological Administration, Beijing 100081, China | 2005 | Science China Earth Sciences2005，48，z2： | 5 |
| 4 | 152 W high-power blue diode laser operated at 447 nm显示文摘We demonstrate a high-power blue diode laser operated at 447 nm combining laser diodes using an optical fiber bundle. As many as 127 diode lasers at 447 nm were coupled into 400 μm/0.22 NA fibers using an aspherical lens group with different focus lengths. The bare fibers were mechanically bundled through high temperature ultraviolet adhesive after the coatings of the 127 fibers were stripped. The diameter of the fiber bundle was 6 mm. The total output power of such a bundle was 152 W with electro-optical conversion efficiency of 27.56%and the RMS power instability was less than ±1% within 3 h. | Peng Wu Ling Zhang Haijuan Yu Xiandan Yuan Zhiyan Zhang Pengfei Zhao Shuzhen Zou Chaojian He Yaoyao Qi Yingying Yang Gang Li Xubao Wang Xuechun Lin | 2017 | Journal of Semiconductors2017，38，7： | 4 |
| 5 | The next detectors for gravitational wave astronomy显示文摘This paper focuses on the next detectors for gravitational wave astronomy which will be required after the current ground based detectors have completed their initial observations, and probably achieved the first direct detection of gravitational waves. The next detectors will need to have greater sensitivity, while also enabling the world array of detectors to have improved angular resolution to allow localisation of signal sources. Sect. 1 of this paper begins by reviewing proposals for the next ground based detectors,and presents an analysis of the sensitivity of an 8 km armlength detector, which is proposed as a safe and cost-effective means to attain a 4-fold improvement in sensitivity. The scientific benefits of creating a pair of such detectors in China and Australia is emphasised. Sect. 2 of this paper discusses the high performance suspension systems for test masses that will be an essential component for future detectors, while sect. 3 discusses solutions to the problem of Newtonian noise which arise from fluctuations in gravity gradient forces acting on test masses. Such gravitational perturbations cannot be shielded, and set limits to low frequency sensitivity unless measured and suppressed. Sects. 4 and 5 address critical operational technologies that will be ongoing issues in future detectors. Sect. 4 addresses the design of thermal compensation systems needed in all high optical power interferometers operating at room temperature. Parametric instability control is addressed in sect. 5. Only recently proven to occur in Advanced LIGO, parametric instability phenomenon brings both risks and opportunities for future detectors. The path to future enhancements of detectors will come from quantum measurement technologies. Sect. 6 focuses on the use of optomechanical devices for obtaining enhanced sensitivity, while sect. 7 reviews a range of quantum measurement options. | BLAIR David JU Li ZHAO ChunNong WEN LinQing MIAO HaiXing CAI RongGen GAO JiangRui LIN XueChun LIU Dong WU Ling-An ZHU ZongHong HAMMOND Giles PAIK Ho Jung FAFONE Viviana ROCCHI Alessio BLAIR Carl MA YiQiu QIN JiaYi PAGE Michael | 2015 | Science China(Physics,Mechanics & Astronomy)2015，58，12： | 3 |
| 6 | Progress of the injection laser system of SG-Ⅱ显示文摘A high power laser system was used to drive the ignition of inertial confinement fusion(ICF), of which the high energy,the uniform focal spot, the accurate laser waveform, and the synchronization between the laser beams are key parameters.To accomplish this, global laser characteristics control should be assured, which was the main purpose of the injection laser system. In this paper, the key technological progress involved in the improvement of the performance of the injection laser of SG-II is reported, including frequency domain control, time domain control, near-field spatial shaping, preamplifier technology, and the optical parametric chirped pulse amplification pump source. | Wei Fan Youen Jiang Jiangfeng Wang Xiaochao Wang Dajie Huang Xinghua Lu Hui Wei Guoyang Li Xue Pan Zhi Qiao Chao Wang He Cheng Peng Zhang Wenfa Huang Zhuli Xiao Shengjia Zhang Xuechun Li Jianqiang Zhu Zunqi Lin | 2018 | High Power Laser Science and Engineering2018，6，2： | 3 |
| 7 | p53 deficiency-induced Smad1 upregulation suppresses tumorigenesis and causes chemoresistance in colorectal cancers显示文摘The DNA damage response helps to maintain genome integrity,suppress tumorigenesis,and mediate the effects of radiotherapy and chemotherapy.Our previous studies have shown that Smad1 is upregulated and activated by Atm in DNA damage response,which can further bind to p53 and promote p53 stabilization.Herewe report another aspect of the interplay between p53 and Smad1.Comparison of rectal tumor against paired paraneoplastic specimens and analysis of>500 colorectal tumors revealed that Smad1 was upregulated in tumor samples,which was attributable to p53 defects.Using MEFs as a model,we found that knockdown of the elevated Smad1 in p532/2 MEFs promoted cell proliferation,E1A/Ras-induced cell transformation,and tumorigenesis.Mechanistic studies suggest that elevated Smad1 and momentary activation inhibit cell proliferation by upregulating p57Kip2 and enhancing Atm–Chk2 activation.Surprisingly,elevated Smad1 appears to have a negative effect on chemotherapy,as colorectal tumors,primary cancer cells,and cell lines with Smad1 knockdown all showed an increase in chemosensitivity,which could be attributable to elevated p57Kip2.These findings underscore the significance of Smad1–p53 interaction in tumor suppression and reveal an unexpected role for Smad1 in chemoresistance of colorectal cancers. | Xinsen Ruan Qiao Zuo Hao Jia Jenny Chau Jinlin Lin Junping Ao Xuechun Xia Huijuan Liu Samy LHabib Chuangang Fu Baojie Li | 2015 | Journal of Molecular Cell Biology2015，7，2： | 2 |
| 8 | Wavefront control of laser beam using optically addressed liquid crystal modulator显示文摘An optically addressed liquid crystal modulator for wavefront control of 1053 nm laser beam is reported in this paper.Its working principle, control method and spatial phase modulation capability are mainly introduced. A new method of measuring the relationship between gray level and phase retardation is proposed. The rationality of the curve is further confirmed by designing special experiments. According to the curve, several spatial phase distributions have been realized by this home-made device. The results show that, not only the maximum phase retardation is larger than2π for 1053 nm wavelength, but also the control accuracy is high. Compared with the liquid crystal on silicon type spatial light modulator, this kind of modulator has the advantages of generating smooth phase distribution and avoiding the black-matrix effect. | Dajie Huang Wei Fan He Cheng Gang Xia Lili Pei Xuechun Li Zunqi Lin | 2018 | High Power Laser Science and Engineering2018，6，2： | 2 |
| 9 | Climate abrupt change in the northern hemisphere for 1920s and 1950s显示文摘 | Ai Wanxiu Lin Xuechun | 1995 | Acta Meteor Sinica1995，9，2： | 1 |
| 10 | A novel blue light generation by frequency doubling of a diode-pumped Nd:YAG thin disk laser显示文摘 | Lin Xuechun Li Ruining | 2004 | Optics Communications2004，237，： | 1 |
| 11 | Design of coherent wideband radiation process in a Nd3+-doped high entropy glass system显示文摘We discover that the spatially coherent radiation within a certain frequency range can be obtained without a common nonlinear optical process.Conventionally,the emission spectra were obtained by de-exciting excited centers from real excited energy levels to the ground state.Our findings are achieved by deploying a high-entropy glass system(HEGS)doped with neodymium ions.The HEGS exhibits a much broader infrared absorption than common glass systems,which can be attributed to be high-frequency optical branch phonons or allowable multi-phonon processes caused by phonon broadening in the system.A broadened phonon-assisted wideband radiation(BPAWR)is induced if the pump laser is absorbed by the system.The subsequent low-threshold self-absorption coherence modulation(SACM)can be controlled by changing excitation wavelengths,sample size,and doping concentrations.The SACM can be red-shifted through the emission of phonons of the excited species and be blue-shifted by absorbing phonons before they are de-excited.There is a time delay up to 1.66 ns between the pump pulse and the BPAWR when measured after traveling through a 35 mm long sample,which is much longer than the Raman process.The BPAWR-SACM can amplify the centered non-absorption band with a gain up to 26.02 dB.These results reveal that the shift of the novel radiation is determined by the frequency of the non-absorption band near the absorption region,and therefore the emission shifts can be modulated by changing the absorption spectrum.When used in fiber lasers,the BPAWR-SACM process may help to achieve tunability. | LINDE ZHANG JINGYUAN ZHANG XIANG WANG MENG TAO GANGTAO DAI JING WU ZHANGWANG MIAO SHIFEI HAN HAIJUAN YU Xuechun Lin | 2022 | Light(Science & Applications)2022，11，9： | 1 |
| 12 | Climate abrupt change in the Northern Hemisphere for 1920s and 1950s 显示文摘 | Ai Wanxiu Lin Xuechun | 1995 | Acta Meteor Sinica1995，9，2： | 1 |
| 13 | Pathogenesis of premature coronary artery disease:Focus on risk factors and genetic variants显示文摘The development of premature coronary artery disease(PCAD)is dependent on both genetic predisposition and traditional risk factors.Strategies for unraveling the genetic basis of PCAD have evolved with the advent of modern technologies.Genome-wide association studies(GWASs)have identified a considerable number of common genetic variants that are associated with PCAD.Most of these genetic variants are attributable to lipid and blood pressure-related single-nucleotide polymorphisms(SNPs).The genetic variants that predispose individuals to developing PCAD may depend on race and ethnicity.Some characteristic genetic variants have been identified in Chinese populations.Although translating this genetic knowledge into clinical applications is still challenging,these genetic variants can be used for CAD phenotype identification,genetic prediction and therapy.In this article we will provide a comprehensive review of genetic variants detected by GWASs that are predicted to contribute to the development of PCAD.We will highlight recent findings regarding CAD-related genetic variants in Chinese populations and discuss the potential clinical utility of genetic variants for preventing and managing PCAD. | Haiming Wang Zifan Liu Junjie Shao Min Jiang Xuechun Lu Lejian Lin Lin Wang Qiang Xu Haomin Zhang Xin Li Jingjing Zhou Yundai Chen Ran Zhang | 2022 | Genes & Diseases2022，9，2： | 1 |
| 14 | Gravitational wave astronomy: the current status显示文摘In the centenary year of Einstein's General Theory of Relativity, this paper reviews the current status of gravitational wave astronomy across a spectrum which stretches from attohertz to kilohertz frequencies. Sect. 1 of this paper reviews the historical development of gravitational wave astronomy from Einstein's first prediction to our current understanding the spectrum. It is shown that detection of signals in the audio frequency spectrum can be expected very soon, and that a north-south pair of next generation detectors would provide large scientific benefits. Sect. 2 reviews the theory of gravitational waves and the principles of detection using laser interferometry. The state of the art Advanced LIGO detectors are then described. These detectors have a high chance of detecting the first events in the near future. Sect. 3 reviews the KAGRA detector currently under development in Japan,which will be the first laser interferometer detector to use cryogenic test masses. Sect. 4 of this paper reviews gravitational wave detection in the nanohertz frequency band using the technique of pulsar timing. Sect. 5 reviews the status of gravitational wave detection in the attohertz frequency band, detectable in the polarisation of the cosmic microwave background, and discusses the prospects for detection of primordial waves from the big bang. The techniques described in sects. 1–5 have already placed significant limits on the strength of gravitational wave sources. Sects. 6 and 7 review ambitious plans for future space based gravitational wave detectors in the millihertz frequency band. Sect. 6 presents a roadmap for development of space based gravitational wave detectors by China while sect. 7 discusses a key enabling technology for space interferometry known as time delay interferometry. | BLAIR David JU Li ZHAO ChunNong WEN LinQing CHU Qi FANG Qi CAI RongGen GAO JiangRui LIN XueChun LIU Dong WU Ling-An ZHU ZongHong REITZE David H. ARAI Koji ZHANG Fan FLAMINIO Raffaele ZHU XingJiang HOBBS George MANCHESTER Richard N. SHANNON Ryan M. BACCIGALUPI Carlo GAO Wei XU Peng BIAN Xing CAO ZhouJian CHANG ZiJing DONG Peng GONG XueFei HUANG ShuangLin JU Peng LUO ZiRen QIANG Li'E TANG WenLin WAN XiaoYun WANG Yue XU ShengNian ZANG YunLong ZHANG HaiPeng LAU Yun-Kau NI Wei-Tou | 2015 | Science China(Physics,Mechanics & Astronomy)2015，58，12： | 1 |
| 15 | Crystal structure of the GDSL family esterase EstL5 in complex with PMSF reveals a branch channel of the active site pocket显示文摘Esterases/lipases from the GDSL family have potential applications in the hydrolysis and synthesis of important esters of pharmaceutical,food,and biotechnical interests.However,the structural and functional understanding of GDSL enzymes is still limited.Here,we report the crystal structure of the GDSL family esterase EstL5 complexed with PMSF at 2.34Åresolution.Intriguingly,the PMSF binding site is not located at the active site pocket but is situated in a surface cavity.At the active site,we note that there is a trapped crystallization solvent 1,6-hexanediol,which mimics the bound ester chain,allowing for further definition of the active site pocket of EstL5.The most striking structural feature of EstL5 is the presence of a unique channel,which extends approximately 18.9Å,with a bottleneck radius of 6.8Å,connecting the active-site pocket and the surface cavity.Replacement of Ser205 with the bulk aromatic residue Trp or Phe could partially block the channel at one end and perturb its access.Reduced enzymatic activity is found in the EstL5 S205W and EstL5 S205F mutants,suggesting the functional relevance of the channel to enzyme catalysis.Our study provides valuable information regarding the properties of the GDSL-family enzymes for designing more efficient and robust biocatalysts. | Runsha Chen Xuechun Gao Ting Nie Jinhong Wu Lin Wang Ali Osman Yan Feng Xianghong Li Yong Zhang | 2023 | Acta Biochimica et Biophysica Sinica2023，55，11： | 0 |
| 16 | 1.2 kW all-fiber narrow-linewidth picosecond MOPA system显示文摘Achieving an all-fiber ultra-fast system with above kW average power and mJ pulse energy is extremely challenging.This paper demonstrated a picosecond monolithic master oscillator power amplifier system at a 25 MHz repetition frequency with an average power of approximately 1.2 kW,a pulse energy of approximately 48μJ and a peak power of approximately 0.45 MW.The nonlinear effects were suppressed by adopting a dispersion stretched seed pulse(with a narrow linewidth of 0.052 nm)and a multi-mode master amplifier with an extra-large mode area;then an ultimate narrow bandwidth of 1.32 nm and a moderately broadened pulse of approximately 107 ps were achieved.Meanwhile,the great spatio-temporal stability was verified experimentally,and no sign of transverse mode instability appeared even at the maximum output power.The system has shown great power and energy capability with a sacrificed beam propagation product of 5.28 mm·mrad.In addition,further scaling of the peak power and pulse energy can be achieved by employing a lower repetition and a conventional compressor. | Jiexi Zuo Haijuan Yu Shuzhen Zou Zhiyong Dong Chaojian He Shuang Xu Chaoyu Ning Xuechun Chen Xinyao Li Xuechun Lin | 2023 | High Power Laser Science and Engineering2023，11，2： | 0 |
| 17 | The PNA wavetrain and the sea surface temperature in the Northern Pacific显示文摘In this paper, the response of the atmospheric 3-5 year cycle to Northern Pacific SST is discussed, The results are as follows:1. From the simultaneous temporal correlations between the Equatorial Eastern Pacific SST, the westerly dirft area’s SST and the Northern Pacific SST at all gridpoints, we find that there are three correlative regions in the Northern Pacific SST field, they are the westerly drift area, the Equatorial Eastern Pacific and the Alaska Bay , and their structures are very similar to the PNA pattern in the atmosphere The difference PTI between the Equatorial Eastern Pacific SST anomaly and the westerly drift area’s SST anomaly can indicate the change of the PNA pattern of the Northern Pacific SST anomaly. It can represent SST change of 65 % areas over the Northern Pacific and can keep watch on El Nino and un-El Nino.2. Simultaneous temporal correlative field between PTI and filtered 500hPa (there is 3-5 year cycle only ) of the Northern Hemisphere presents clear PNA structure. The | Lin Xuechun Institute of Synoptic and Dynamic Meteorology, Academy of Meteorological Science, SMA, Beijing, China | 1990 | Acta Oceanologica Sinica1990，9，4： | 0 |
| 18 | Suppression of amplitude modulation induced by polarization mode dispersion using a multi-degree-of-freedom fiber filter显示文摘Polarization mode dispersion(PMD) in fibers for high-power lasers can induce significant frequency modulation to amplitude modulation(FM-to-AM) conversion. However, existing techniques are not sufficiently flexible to achieve efficient compensation for such FM-to-AM conversion. By analyzing the nonuniform transmission spectrum caused by PMD, we found that the large-scale envelope of the transmission spectrum has more serious impacts on the amount of AM. In order to suppress the PMD-induced FM-to-AM conversion, we propose a novel tunable spectral filter with multiple degrees of freedom based on a half-wave plate, a nematic liquid crystal, and an axis-rotated polarizationmaintaining fiber. Peak wavelength, free spectral range(FSR), and modulation depth of the filter are decoupled and can be controlled independently, which is verified through both simulations and experiments. The filter is utilized to compensate for the PMD-induced FM-to-AM conversion in the front end of a high-power laser facility. The results indicate that, for a pulse with phase-modulation frequency of 22.82 GHz, the FM-to-AM conversion could be reduced from 18% to 3.2% within a short time and maintained below 6.5% for 3 h. The proposed filter is also promising for other applications that require flexible spectral control such as high-speed channel selection in optical communication networks. | Rao Li Youen Jiang Zhi Qiao Canhong Huang Wei Fan Xuechun Li Zunqi Lin | 2018 | High Power Laser Science and Engineering2018，6，4： | 0 |
| 19 | THE ALTERNATE-SEASONAL CORRELATION OF LONG—RANGE WEATHER PROCESS显示文摘In this paper,the correlation of meteorological elements at an interval of 5—7 months,i.e.,the alternate-seasonalcorrelation,is thoroughly analyzed.The results show that the alternate-seasonal correlation is an important phenome-non in the long-range weather process,and it has a significant latitude effect and seasonal variations.Furthermore,therelation between this phenomenon and SST in the North Pacific is discussed. | Lin Xuechun Zhang Ruixue Chinese Academy of Meteorological Sciences,Beijing 100081 | 1992 | Acta meteorologica Sinica1992，6，4： | 0 |
| 20 | Effects of pulse width and repetition rate of pulsed laser on kinetics and production of singlet oxygen luminescence显示文摘Pulsed and continuous-wave(CW)lasers have been widely used as the light sources for photodynamic therapy(PDT)treatment.Singlet oxygen(^(1)O_(2))is known to be a major cytotoxic agent in type-II PDT and can be directly detected by its near-infrared luminescence at 1270 nm.As compared to CW laser excitation,the effiects of pulse width and repetition rate of pulsed laser on the kinetics and production of^(1)O_(2)luminescence were quantitatively studied during photosensitization of Rose Bengal.Significant di®erence in kinetics of^(1)O_(2)luminescence was found under the excitation with various pulse widths of nanosecond,microsecond and CW irradiation with power of 20mW.The peak intensity and duration of^(1)O_(2)production varied with the pulse widths for pulsed laser excitation,while the^(1)O_(2)was generated continuously and its production reached a steady state with CW excitation.However,no significant di®erence(P>0:05)in integral^(1)O_(2)production was observed.The results suggest that the PDT efficacy using pulsed laser may be identical to the CW laser with the same wavelength and the same average°uence rate below a threshold in solution. | Defu Chen Ying Wang Buhong Li Huiyun Lin Xuechun Lin Ying Gu | 2016 | Journal of Innovative Optical Health Sciences2016，9，6： | 0 |
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