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| 1 | The Genome of Dendrobium officinale Illuminates the Biology of the Important Traditional Chinese Orchid Herb显示文摘 | Liang Yan Xiao Wang Hui Liu Yang Tian Jinmin Lian Ruijuan Yang ShumeiHao Xuanjun Wang Shengchao Yang Qiye Li Shuai Qi Ling Kui Moses Okpekum Xiao Ma Jiajin Zhang Zhaoli Ding Guojie Zhang Wen Wang Yang Dong Jun Sheng | 2015 | Molecular Plant2015,8,6: | 64 |
| 2 | Paleo-Environment Reconstruction of the Middle Permian Lucaogou Formation,Southeastern Junggar Basin,NW China:Implications for the Mechanism of Organic Matter Enrichment in Ancient Lake显示文摘The Middle Permian Lucaogou Formation is the source rock and the main oil shale producing formation in the southeastern Junggar Basin.This study focused on the Lucaogou Formation exposed in two outcrop sections on the northern flank of the Bogda Mountain,namely the Jingjingzigou and Dalongkou sections.Here,we present integrated analysis of the sedimentology,major and trace elements,mineral components and total organic carbon contents.The paleo-environment was reconstructed including provenance,redox conditions,paleo-salinity,chemical weathering intensity and primary organic matter productivity.The results showed that the upper and lower units were deposited in distinct depositional environments with different organic matter accumulation mechanisms.The lower unit was characterized by low lake level,dry climate,fresh-brackish and well-oxygenated water.While during the deposition of the upper unit the lake level rose,climate turned wetter and the bottom water became less oxidized and much saltier.The mechanism of the organic matter accumulation is different for these two units.The preserved organic matters were mainly controlled by the primary productivity in the lower unit and by the redox conditions in the upper unit. | Dawei Cheng Chuanmin Zhou Zhijie Zhang Xuanjun Yuan Yinhe Liu Xingyu Chen | 2022 | Journal of Earth Science2022,33,4: | 1 |
| 3 | Effect of Nd–Co substitution on magnetic and microwave absorption properties of SrFe 12 O 19 hexaferrites显示文摘 | Zeyang Zhang Xiangxuan Liu Xuanjun Wang Youpeng Wu Rong Li | 2012 | Journal of Alloys and Compounds2012,,: | 1 |
| 4 | Mesh model building and migration and accumulation simulation of 3D hydrocarbon carrier system显示文摘Migration and accumulation simulation of oil and gas in carrier systems has always been a difficult subject in the quantitative study of petroleum geology. In view of the fact that the traditional geological modeling technology can not establish the interrelation of carriers in three dimensional space, we have proposed a hybrid-dimensional mesh modeling technology consisting of body(stratum), surfaces(faults and unconformities), lines and points, which provides an important research method for the description of geometry of sand bodies, faults and unconformities, the 3 D geological modeling of complex tectonic areas, and the simulation of hydrocarbon migration and accumulation. Furthermore, we have advanced a 3 D hydrocarbon migration pathway tracking method based on the hybrid-dimensional mesh of the carrier system. The application of this technology in western Luliang Uplift of Junggar Basin shows that the technology can effectively characterize the transport effect of fault planes, unconformities and sand bodies, indicate the hydrocarbon migration pathways, simulate the process of oil accumulation, reservoir adjustment and secondary reservoir formation, predict the hydrocarbon distribution. It is found through the simulation that the areas around the paleo-oil reservoir and covered by migration pathways are favorable sites for oil and gas distribution. | GUO Qiulin LIU Jifeng CHEN Ningsheng WU Xiaozhi REN Hongjia WEI Yanzhao CHEN Gang GONG Deyu YUAN Xuanjun | 2018 | Petroleum Exploration and Development2018,45,6: | 0 |
| 5 | Non-cytotoxic nanoparticles re-educating macrophages achieving both innate and adaptive immune responses for tumor therapy显示文摘Macrophages are important antigen-presenting cells to combat tumor via both innate and adaptive immunity,while they are programmed toM2 phenotype in established tumors and instead promote cancer development and metastasis.Here,we develop a nanomedicine that can re-educate M2 polarized macrophages to restore their anti-tumor activities.The nanomedicine has a core-shell structure to co-load IPI549,a PI3Kγinhibitor,and CpG,a Toll-like receptor 9 agonist.Specifically,the hydrophobic IPI549 is self-assembled into a pure drug nano-core,while MOF shell layer is coated for CpG encapsulation,achieving extra-high total drugs loading of 44%.Such nanosystem could facilitate intracellular delivery of the payloads but without any cytotoxicity,displaying excellent biocompatibility.After entering macrophages,the released IPI549 and CpG exert a synergistic effect to switch macrophages from M2 to M1 phenotype,which enables anti-tumor activities via directly engulfing tumor cells or excreting tumor killing cytokines.Moreover,tumor antigens released from the dying tumor cells could be effectively presented by the re-educated macrophages owing to the up-regulation of various antigen presenting mediators,resulting in infiltration and activation of cytotoxic T lymphocytes.As a result,the nanosystem triggers a robust antitumor immune response in combination with PD-L1 antibody to inhibit tumor growth and metastasis.This work provides a non-cytotoxic nanomedicine to modulate tumor immune microenvironment by reprograming macrophages. | Shengmei Wang Xuanjun Liu Minghua Yang Linqi Ouyang Jinsong Ding Shengfeng Wang Wenhu Zhou | 2022 | Asian Journal of Pharmaceutical Sciences2022,17,4: | 0 |
| 6 | Investigation of hydroxyl-terminated polybutadiene propellant breaking characteristics and mechanism impacted by submerged cavitation water jet显示文摘A submerged cavitation water jet(SCWJ)is an effective method to recycle solid propellant from obsolete solid engines by the breaking method.Solid propellant's breaking modes and mechanical process under SCWJ impact are unclear.This study aims to understand those impact breaking mechanisms.The hydroxyl-terminated polybutadiene(HTPB)propellant was chosen as the research material,and a self-designed test system was used to conduct impact tests at four different working pressures.The high-speed camera characterized crack propagation,and the DIC method calculated strain change during the impact process.Besides,micro and macro fracture morphologies were characterized by scanning electron microscope(SEM)and computed tomography(CT)scanning.The results reveal that the compressive strain concentration region locates right below the nozzle,and the shear strain region distributes symmetrically with the jet axis,which increases to 4% at first 16th ms,the compressive strain rises to 2% and 6% in the axial and transverse direction,respectively.The two tensile cracks formed first at the compression strain concentrate region,and there generate many shear cracks around the tensile cracks,and those shear cracks that develop and aggregate cause the cracks to become wider and cut through the tensile cracks,forming the tensile-shear cracks and the impact parts eventually fail.The HTPB propellant forms a breaking hole shaped conical after impact 10 s.The mass loss increases by 17 times at maximum,with the working pressure increasing by three times.Meanwhile,the damage value of the breaking hole remaining on the surface increases by 7.8 times while 2.9 times in the depth of the breaking hole.The breaking efficiency is closely affected by working pressures.The failure modes of HTPB impacted by SCWJ are classified as tensile crack-dominated and tensile-shear crack-dominated damage mechanisms. | Wenjun Zhou Meng Zhao Bo Liu Youzhi Ma Youzhi Zhang Xuanjun Wang | 2024 | Defence Technology(防务技术)2024,33,3: | 0 |
| 7 | Theory, Technology and Practice of Unconventional Petroleum Geology显示文摘0 INTRODUCTION The breakthroughs in unconventional petroleum have a great impact on world petroleum industry and innovation in petroleum geology(Dou et al,2022;Jia,2017;Zou et al.,2015b,2014a;Yerkin,2012;Pollastro,2007;Schmoker,1995).The exploration and development evolution from conventional petroleum to unconventional petroleum and more and more frequent industrial activities of exploring petroleum inside sources kitchen have deepened theoretical understanding of unconventional petroleum geology and promoted technical research and development(Jia et al.,2021,2017;Jin et al.,2021;Zhao W Z et al.,2020;Ma Y S et al.,2018,2012;Zou et al.,2018b,2016,2009;Dai et al.,2012).We have introduced and extended the theory of continuous hydrocarbon accumulation since 2008 and published several papers/books(in Chinese and English)with respect to unconventional petroleum geology since 2009,basically forming the theoretical framework for this discipline(Yang et al.,2022a,2021a,2019a,,2015a;Zou et al.,2019c,2017b,2014a,,2013a).In this paper,we present the background of unconventional petroleum geology,review the latest theoretical and technological progress in unconventional petroleum geology,introduce relevant thinking and practices in China,and explore the pathway of unconventional petroleum revolution and multi-energy coordinated development in super energy basins,hopefully to promote the unconventional petroleum geology and industry development. | Caineng Zou Zhi Yang Guosheng Zhang Rukai Zhu Shizhen Tao Xuanjun Yuan Lianhua Hou Dazhong Dong Qiulin Guo Yan Song Qiquan Ran Zhen Qiu Songtao Wu Feng Ma Bin Bai Lan Wang Bo Xiong Songqi Pan Hanlin Liu Xiaoni Wang | 2023 | Journal of Earth Science2023,34,4: | 0 |
| 8 | A PIID-DTBT based semi-conducting polymer dots with broad and strong optical absorption in the visible-light region: Highly effective contrast agents for multiscale and multi-spectral photoacoustic imaging显示文摘作为一种混合成像技术, photoacoustic 成像(白族) 能提供纸巾的多尺度的词法信息,并且多光谱的白族(MSPAI ) 的使用能恢复兴趣的色基的空间分发,例如在纸巾以内的血红素。此处,我们开发了能很有效地为复杂生物纸巾的更全面的描述把多尺度的白族与 MSPAI 相结合的一个对比代理人。明确地,我们开发了新奇 PIID-DTBT 在可见光的区域(500-700 nm ) 显示出宽广、强壮的光吸收的基于的半导体的聚合物点(Pdots ) 。金 nanoparticles (GNP ) 和金 nanorods (GNR ) 的表演,作为优秀 photoacoustic 对比代理人被验证了,基于多尺度的白族系统与 Pdots 的相比。两前 vivo 并且在 vivo,实验比有在在一样的 700 nm 的 GNR 的 GNP 和显示出的类似的 photoacoustic 性能集中的证明 Pdots 在 532 nm 有更好的 photoacoustic 变换效率集中。Photostability 和毒性测试证明 Pdots 是 photostable 和 biocompatible。更重要地,一在里面 vivo MSPAI 实验显示 Pdots 比血有更好的 photoacoustic 性能,因此,信号能精确地从脉管富人的纸巾的背景被提取。我们的工作基于多尺度的白族和 MSPAI 相对血容器为损害的精确本地化作为高度有效的对比代理人表明 Pdots 的大潜力。 | Jian Zhang Haobin Chen Ting Zhou Limei Wang Duyang Gao Xuanjun Zhang Yubin Liu Changfeng Wu Zhen Yuan | 2017 | Nano Research2017,10,1: | 0 |