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| 1 | Composition and structure design of three-layered composite phosphors for high color rendering chip-on-board light-emitting diode devices显示文摘A three-layered phosphor structure was designed and prepared by the spin coating of BaSi_(2)N_(2)O_(2):Eu(cyan-emitting)and(Sr,Ca)AlSiN_(3):Eu(red-emitting)phosphor films on the yellowemitting Y_(3)Al_(5)O_(12):Ce(YAG:Ce)phosphor ceramic synthesized by the solid-state reaction under vacuum sintering.In order to achieve high color rendering lighting,the influence of the composition and structure of the three-layered phosphors on the optical,thermal,and electrical properties of the chip-on-board(COB)packaged white-light-emitting diodes(WLEDs)was studied systematically.The WLED with the structure of“red+cyan+yellow”(R+C+Y)three-layered phosphor generated neutral white light and had a luminous efficacy of 75 lm/W,the fidelity index(R_(f))of 93,the gamut index(R_(g))of 97,and the correlated color temperature(CCT)of 3852 K.Under the excitation of laser diode(LD),the layer-structured phosphor yielded the white light with a luminous efficacy of 120 lm/W,color rendering index(CRI)of 90,and CCT of 5988 K.The result indicates that the three-layered phosphor structure is a promising candidate to achieve high color rendering and high luminous efficacy lighting. | Xin LIU Xinglu QIAN Peng ZHENG Xiaopu CHEN Yagang FENG Yun SHI Jun ZOU Rongjun XIE Jiang LI | 2021 | Journal of Advanced Ceramics2021，10，4： | 5 |
| 2 | Rational development of a human antibody cocktail that deploys multiple functions to confer Pan-SARS-CoVs protection显示文摘Structural principles underlying the composition and synergistic mechanisms of protective monoclonal antibody cocktails are poorly defined.Here,we exploited antibody cooperativity to develop a therapeutic antibody cocktail against SARS-CoV-2.On the basis of our previously identified humanized cross-neutralizing antibody H014,we systematically an a lyzed a fully human n aive antibody library and rationally identified a potent neutralizing antibody partner,P17,which confers effective protection in animal model.Cryo-EM studies dissected the nature of the P17 epitope,which is SARS-CoV-2 specific and distinctly different from that of HOI4.High-resolution structure of the SARS-CoV-2 spike in complex with HOM and P17,together with functional investigations revealed that in a two-antibody cocktail,synergistic neutralization was achieved by S1 shielding and conformational locking,thereby blocking receptor attachment and viral membrane fusion,conferring high potency as well as robustness against viral mutation escape.Furthermore,cluster analysis identified a hypothetical 3rd antibody partner for further reinforcing the cocktail as pan-SARS-CoVs therapeutics. | Hangping Yao Yao Sun Yong-Qiang Deng Nan Wang Yongcong Tan Na-Na Zhang Xiao-Feng Li Chao Kong Yan-Peng Xuc Qi Chen Tian-Shu Cao Hui Zhao Xintian Yan Lei Cao Zhe Lv Dandan Zhu Rui Feng Nanping Wu Wenhai Zhang Yuhao Hu Keda Chen Rong-Rong Zhang Qingyu Lv Shihui Sun Yunhua Zhou Run Yan Guan Yang Xinglu Chanjuan Liu Xiangyun Lu Linfang Cheng Hongying Qiu Xing-Yao Huang Tianhao Weng Danrong Shi Weidong Jiang Junbin Shao Lei Wang Jie Zhang Tao Jiang Guojun Lang Cheng-Feng Qinc Lanjuan Li Xiangxi Wang | 2021 | Cell Research2021，31，1： | 5 |
| 3 | Effectiveness and safety of Ginkgo biloba extract(GBE50)in the treatment of dizziness caused by cerebral arteriosclerosis:a multi-center,double-blind,randomized controlled trial显示文摘OBJECTIVE:To evaluate the effectiveness and safety of Ginkgo biloba extract(GBE50)in the treatment of dizziness caused by cerebral arteriosclerosis.METHODS:This was a multi-center,double-blind,double-dummy,positive-controlled,parallel randomized controlled clinical trial with 1∶1 allocation.We recruited 404 patients with dizziness caused by cerebral arteriosclerosis(blood stasis symptom pattern)in 10 hospitals in China.GBE50 group received GBE50 and Naoxinqing tablet(NXQ)of mimetic agent,control group received NXQ and GBE50 of mimetic agent.The main outcome was Traditional Chinese Medicine(TCM)symptom pattern score of blood stasis after 6 weeks.The secondary outcomes were changes in the dizziness handicap inventory(DHI)score,vertigo visual analogue scale(VAS)score,the university of California vertigo questionnaire(UCLA-DQ)score and single-item symptom score of TCM from baseline to 2,4 and 6 weeks.Safety indicators included the incidence of adverse events,severe adverse events and laboratory examination including blood routine,liver function,renal function,and so forth.RESULTS:The total effective rate of TCM symptom pattern score in the GBE50 group after 6 weeks of treatment was higher than that in the control group,the difference in rate was statistically significant(92.67%vs 83.07%,P=0.004).Compared with the control group,there was no difference in the incidence of adverse reactions(9.95%vs 14.85%,P=0.136).CONCLUSION:The treatment of dizziness caused by cerebral arteriosclerosis with GBE50 is effective,safe and reliable. | SHA Rina TANG Lu DU Yawei WU Shengxian SHI Huawei ZOU Hongxin ZHANG Xuran DONG Xinglu ZHOU Li | 2022 | Journal of Traditional Chinese Medicine2022，42，1： | 5 |
| 4 | Development of optical-thermal coupled model for phosphor-converted LEDs显示文摘In this review, first, we discussed the effect of phosphor features on optical properties by the software simulation in detail. A combination of these parameters: phosphor material, phosphor particle size and particle distribution, phosphor layer concentration, phosphor layer thickness, geometry, and location of the phosphor layer, will result in the final optical performance of the phosphor layer. Secondly, we introduced how to improve light extraction efficiency with various proposed methods. Thirdly, we summarized the thermal models to predict the phosphor temperature and the junction temperature. To stabilize the optical performance of phosphor-converted light emitting diodes (PC-LEDs), much effort has been made to reduce the junction temperature of the LED chips. The phosphor temperature, a critical reliability concern for PC-LEDs, should be attracted academic interest. Finally, we summed up optical-thermal coupled model for phosphors and summarized future optical- thermal issues exploring the light quality for LEDs. We foresee that optical-thermal coupled model for PC-LEDs should be paid more attention in the future. | Xinglu QIAN Jun ZOU Mingming SHI Bobo YANG Yang LI Ziming WANG Yiming LIU Zizhuan LIU Fei ZHENG | 2019 | Frontiers of Optoelectronics2019，12，3： | 2 |
| 5 | Corporate Entrepreneurship, Informal Ties, and Firm Performance: Evidence from China显示文摘一个公司怎么能在转变经济通过社团的 entrepreneurship 完成优异性能?探讨这个问题,我们利用基于资源的看法和机构的理论在满足不同社团的企业的活动面对的资源需要探索企业关系和政治关系的不同角色即,内部革新,冒险并且战略更新。用来自在中国的珍珠河三角洲区域的 228 个公司的数据,我们的实验调查结果表明社团的企业的活动断然总是不在转变经济导致性能。而且,企业关系的高水平的拥有对内部革新和战略更新的成功更有益,当政治关系的高水平的拥有贡献更多到冒险的成功时。 | Xinglu Zhao Jianqi Zhang | 2013 | Frontiers of Business Research in China2013，7，1： | 2 |
| 6 | Comprehensive sizing and optimization method for series-hybrid unmanned convertiplane显示文摘This paper presents a novel sizing and optimization approach for the emerging serieshybrid unmanned convertiplane,which can be used to translate the top-level design requirements into the design parameters corresponding to the optimal power supply strategy and minimum total takeoff weight.The method comprehensively considers the design constraints in the rotor,fixedwing,and transition modes,and pays special attention to the characteristic response of Series Hybrid Electric System(S-HES)in complex application scenarios,especially the coupling of battery power,energy,and state-of-charge under high-power discharge conditions,the variation of fuel economy,and the adjustment of power supply strategy.With proposed method,it's possible to rapidly explore the design space in the initial design stage and find out the optimal design results with high confidence.A case study was proposed to verify the approach.The results reveal the particularity of convertiplane in terms of power requirements,and prove the necessity to consider detailed S-HES characteristic responses during parameter determination.The optimal design parameters were obtained through the hybrid control parameter optimization,which verified the effectiveness of proposed method.Possible errors and corresponding correction methods were also presented. | Gang CHEN Dongli MA Yuhong JIA Xinglu XIA Cheng HE | 2021 | Chinese Journal of Aeronautics2021，34，4： | 2 |
| 7 | Knowledge, attitude and practice survey on immunization service delivery in Guangxi and Gansu, China 显示文摘 | Xinglu Zhang Lixia Wang Xu Zhu | 1999 | Social Science & Medicine1999，49，8： | 1 |
| 8 | Pore structure and mechanical properties of directionally solidi ed porous aluminum alloys显示文摘Porous aluminum alloys produced by the metal-gas eutectic method or GASAR process need to be performed under a certain pressure of hydrogen, and to carry over melt to a tailor-made apparatus that ensures directional solidif ication. Hydrogen is driven out of the melt, and then the quasi-cylindrical pores normal to the solidif ication front are usually formed. In the research, the effects of processing parameters(saturation pressure, solidif ication pressure, temperature, and holding time) on the pore structure and porosity of porous aluminum alloys were analyzed. The mechanical properties of Al-Mg alloys were studied by the compressive tests, and the advantages of the porous structure were indicated. By using the GASAR method, pure aluminum, Al-3wt.%Mg, Al-6wt.%Mg and Al-35wt.%Mg alloys with oriented pores have been successfully produced under processing conditions of varying gas pressure, and the relationship between the f inal pore structure and the solidif ication pressure, as well as the inf luences of Mg quantity on the pore size, porosity and mechanical properties of AlMg alloy were investigated. The results show that a higher pressure of solidif ication tends to yield smaller pores in aluminum and its alloys. In the case of Al-Mg alloys, it was proved that with the increasing of Mg amount, the mechanical properties of the alloys sharply deteriorate. However, since Al-3%Mg and Al-6wt.%Mg alloys are ductile metals, their porous samples have greater compressive strength than that of the dense samples due to the existence of pores. It gives the opportunity to use them in industry at the same conditions as dense alloys with savings in weight and material consumption. | Komissarchuk Olga Xu Zhengbin Hao Hai Zhang Xinglu Vladimir Karpov | 2014 | China Foundry2014，11，1： | 1 |
| 9 | Abrogation of Akt signaling by Isobavachalcone contributes to its anti-pro- liferative effects towards human cancer cells 显示文摘 | Jing Hui Zhou Xinglu Dong Xiaowu | 2010 | Cancer Letters2010，294，2： | 1 |
| 10 | Synthesis of Aqueous CdTe/CdS/ZnS Core/shell/shell Quantum Dots by a Chemical Aerosol Flow Method显示文摘 | Chuanmiao Yan Fangqiong Tang Linlin Li Hongbo Li Xinglu Huang Dong Chen Xianwei Meng Jun Ren | 2010 | Nanoscale Research Letters2010，，1： | 1 |
| 11 | Studies on the cold resistance of Cassava显示文摘 | Luo Xinglu Huang Qiufeng | 2012 | Journal of Agricultural Science2012，4，6： | 1 |
| 12 | Abrogation of Akt signaling by isobavachalcone contributes to its anti-proliferative effects towards human cancer cells显示文摘 | Jing Hui Zhou Xinglu Dong Xiaowu | 2010 | Cancer Letters2010，294，2： | 1 |
| 13 | Abrogation of Akt signaling by isobavachalcone contributes to its anti-proliferative effects towards human cancer cells显示文摘 | Jing Hui Zhou Xinglu Dong Xiaowu | 2010 | Cancer Letters2010，294，2： | 1 |
| 14 | The effect of the shape of mesoporous silica nanoparticles on cellular uptake and cell function显示文摘 | Xinglu Huang Xu Teng Dong Chen Fangqiong Tang Junqi He | 2009 | Biomaterials2009，，3： | 1 |
| 15 | Knowledge,attitude and practice survey on immunization service delivery in Guangxi and Gansu,China显示文摘 | Zhang Xinglu Wang Lixia Zhu Xu | 1999 | Social Science & Medicine1999，49，： | 1 |
| 16 | Optimization and analysis of composite sandwich box beam for solar drones显示文摘Solar drones have garnered considerably research attention in recent years due to their continuous cruising capability,and the feasibility of design schemes is sensitive to the weight of structure.Sandwich box beam composed of carbon fiber and polymethacrylimide(PMI)foam is conducive to realize the lightweight of structure.In this study,a two-stage optimization design methodology for sandwich box beam is proposed.This methodology is primarily based on a low-order analytical method for evaluating stress/deflection and the linear buckling analysis method combined with experimental correction factor for predicting the buckling eigenvalues.Subsequently,a case study was conducted using an 18-m wingspan solar drone,where the results of mechanical test verified the optimization results.For validating the use of sandwich box beam in solar drones of other scales,additional analysis was conducted based on three aspects:(A)effects of stiffness and stability constraints on the design of sandwich box beam;(B)crucial role of the weight of foam inter layer and application scope of sandwich box beam;(C)best method to improve the buckling eigenvalue of sandwich box beam.Overall,the methodology and general rules presented in this paper can support the design of light wing beam for solar drones. | Liang ZHANG Dongli MA Muqing YANG Xinglu XIA Yuan YAO | 2021 | Chinese Journal of Aeronautics2021，34，10： | 1 |
| 17 | Investigation of leak detection method by means of measuring the pressure increment in vacuum显示文摘 | Gu Boqin Huang Xinglu | 2006 | Vacuum2006，809，： | 1 |
| 18 | Abrogation of aktsignaling by isobavachalcone contributes to its anti-proliferativeeffects towards human cancer cells显示文摘 | JING Hui ZHOU Xinglu DONG Xiaowu | 2010 | Cancer Letters2010，294，2： | 1 |
| 19 | Supplementing Qi and activating blood circulation method to treat vertebrobasilar dolichoectasia with posterior circulatory watershed infarction:a case report of two patients显示文摘Vertebrobasilar dolichoectasia(VBD),a rare posterior circulation vascular variant disease,is an important risk factor for many acute cerebrovascular diseases.An insufficient understanding of VBD often leads to misdiagnose.Two cases of VBD that were initially diagnosed as posterior circulation watershed infarction are reported here.Absence of common causes of stroke including hypoperfusion,blood system diseases,carotid and aortic dissection,and eosinophil elevation,the symptoms of the 2 patients met the diagnostic criteria of VBD.Both patients displayed symptoms that were in line with the Traditional Chinese Medicine(TCM)syndrome pattern of'Qi deficiency and blood stasis'.Accordingly,they were comprehensively treated with Supplementing Qi and activating blood circulation method.The clinical manifestations of the 2 patients were remarkably improved and no recurrence of watershed infarction was found in a 1-year follow-up.A detailed medical history and laboratory examination are capable of improving diagnostic accuracy of VBD.TCM treatment based on syndrome identification might be a promising candidate for VBD management. | LI He SU Wenquan LI Shanshan JI Hanrui CHENG Jiangyan CUI Fangyuan TANG Lu ZHOU Li GAO Ying DONG Xinglu | 2023 | Journal of Traditional Chinese Medicine2023，43，4： | 0 |
| 20 | Research and Design of Consistent Project Cases for the Software Engineering Course Group显示文摘In order to enhance the abilities of practical innovation and solving complex engineering problems of students in the engineering context,we design a course cluster teaching model based on a unified enterprise-level project case.The program divides the knowledge points required by the project into the corresponding courses,and divides their realization into the practical teaching cases,so as to realize the design of teaching practice cases embodied in the unified project framework.This model allows students to practice projects based on the unified project background while learning knowledge from different courses.It not only allows students to learn abstract,fragmented,and difficult-to-understand knowledge systems thoroughly,but also integrates the knowledge into the practice of the enterprise-level project development,helping students experience the value of knowledge in complex engineering projects and thus improving their ability to solve complex engineering problems while learning theoretical knowledge. | Junwei Du Guozhu Liu Quan Liu Xinglu Ma Meijiao Xu Wenfeng Liu | 2023 | 计算机教育2023，，12： | 0 |
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