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| 1 | Recent progress of integrated circuits and optoelectronic chips显示文摘Integrated circuits(ICs)and optoelectronic chips are the foundation stones of the modern information society.The IC industry has been driven by the so-called'Moore's law'in the past 60 years,and now has entered the post Moore's law era.In this paper,we review the recent progress of ICs and optoelectronic chips.The research status,technical challenges and development trend of devices,chips and integrated technologies of typical IC and optoelectronic chips are focused on.The main contents include the development law of IC and optoelectronic chip technology,the IC design and processing technology,emerging memory and chip architecture,brain-like chip structure and its mechanism,heterogeneous integration,quantum chip technology,silicon photonics chip technology,integrated microwave photonic chip,and optoelectronic hybrid integrated chip. | Yue HAO Shuiying XIANG Genquan HAN Jincheng ZHANG Xiaohua MA Zhangming ZHU Xingxing GUO Yahui ZHANG Yanan HAN Ziwei SONG Yan LIU Ling YANG Hong ZHOU Jiangyi SHI Wei ZHANG Min XU Weisheng ZHAO Biao PAN Yangqi HUANG Qi LIU Yimao CAI Jian ZHU Xin OU Tiangui YOU Huaqiang WU Bin GAO Zhiyong ZHANG Guoping GUO Yonghua CHEN Yong LIU Xiangfei CHEN Chunlai XUE Xingjun WANG Lixia ZHAO Xihua ZOU Lianshan YAN Ming LI | 2021 | Science China(Information Sciences)2021，64，10： | 7 |
| 2 | Allotransplantation of adult spinal cord tissues after complete transected spinal cord injury: long-term survival and functional recovery in canines显示文摘Spinal cord injury(SCI), especially complete transected SCI, leads to loss of cells and extracellular matrix and functional impairments. In a previous study, we transplanted adult spinal cord tissues(aSCTs) to replace lost tissues and facilitate recovery in a rat SCI model. However, rodents display considerable differences from human patients in the scale, anatomy and functions of spinal cord systems, and responses after injury. Thus, use of a large animal SCI model is required to examine the repair efficiency of potential therapeutic approaches. In this study, we transplanted allogenic aSCTs from adult dogs to the lesion area of canines after complete transection of the thoracic spinal cord, and investigated the long-term cell survival and functional recovery. To enhance repair efficiency, a growth factor cocktail was added during aSCT transplantation, providing a favorable microenvironment. The results showed that transplantation of a SCTs, in particular with the addition of growth factors, significantly improves locomotor function restoration and increases the number of neurofilament-, microtubule-associated protein2-, 5-hydroxytryptamine-, choline acetyltransferase-and tyrosine hydroxylase-positive neurons in the lesion area at 6 months post-surgery. In addition, we demonstrated that donor neurons in a SCTs can survive for a long period after transplantation. This study showed for the first time that transplanting aSCTs combined with growth factor supplementation facilitates reconstruction of injured spinal cords, and consequently promotes long lasting motor function recovery in a large animal complete transected SCI model, and therefore could be considered as a possible therapeutic strategy in humans. | He Shen Shuyu Wu Xi Chen Bai Xu Dezun Ma Yannan Zhao Yan Zhuang Bing Chen Xianglin Hou Jiayin Li Yudong Cao Xianyong Fu Jun Tan Wen Yin Juan Li Li Meng Ya Shi Zhifeng Xiao Xingjun Jiang Jianwu Dai | 2020 | Science China(Life Sciences)2020，63，12： | 3 |
| 3 | Hybrid-integrated high-performance microwave photonic filter with switchable response显示文摘The integrated microwave photonic filter(MPF),as a compelling candidate for next-generation radio-frequency(RF)applications,has been widely investigated for decades.However,most integrated MPFs reported thus far have merely incorporated passive photonic components onto a chip-scale platform,while all necessary active devices are still bulk and discrete.Though few attempts to higher photonic integration of MPFs have been executed,the achieved filtering performances are fairly limited,which impedes the pathway to practical deployments.Here,we demonstrate,for the first time to our knowledge,an all-integrated MPF combined with high filtering performances,through hybrid integration of an In P chip-based laser and a monolithic silicon photonic circuit consisting of a dual-drive Mach–Zehnder modulator,a high-Q ring resonator,and a photodetector.This integrated MPF exhibits a high spectral resolution as narrow as 360 MHz,a wide-frequency tunable range covering the S-band to K-band(3 to 25 GHz),and a large rejection ratio of>40 d B.Moreover,the filtering response can be agilely switched between the bandpass and band-stop function with a transient respond time(48μs).Compared with previous MPFs in a similar integration level,the obtained spectral resolution in this work is dramatically improved by nearly one order of magnitude,while the valid frequency tunable range is broadened more than twice,which can satisfy the essential filtering requirements in actual RF systems.As a paradigm demonstration oriented to real-world scenarios,high-resolution RF filtering of realistic microwave signals aiming for interference rejection and channel selection is performed.Our work points out a feasible route to a miniaturized,high-performance,and cost-effective MPF leveraging hybrid integration approach,thus enabling a range of RF applications from wireless communication to radar toward the higher-frequency region,more compact size,and lower power consumption. | YUANSHENG TAO HAOWEN SHU XINGJUN WANG MING JIN ZIHAN TAO FENGHE YANG JINGBO SHI JUN QIN | 2021 | Photonics Research2021，9，8： | 2 |
| 4 | Ultra-wideband direct-sequence design approach for multiple narrowb and interference suppression显示文摘A novel direct sequence(DS) design method for sup pressing the narrowband interference in DS spread spectrum ultra-wideband receivers is proposed.The method has low com putational complexity and can be easily implemented in practica systems.Simulation results prove that the proposed method i effective to suppress the narrowband interference.Therefore,the integrity of both the ultra-wide bandwidth and the narrowband sys tems can be highly enhanced. | Huibin Xu Junjun Guo Xingjun Shi | 2013 | Journal of Systems Engineering and Electronics2013，24，3： | 1 |
| 5 | Cloning and Bioinformatics Analysis of hcp Gene in Aeromonas hydrophila显示文摘[Objectives]To explore the function of hcp gene in Aeromonas hydrophila.[Methods]A pair of specific primers was designed referring to the hcp gene sequence of A.hydrophila.The hcp gene was amplified by PCR,and performed bioinformatics analysis.[Results]The hcp gene had a total length of 1650 bp and encoded 549 amino acids.The theoretical molecular weight of the protein predicted was about 59476.44 kDa.After predicting the N-terminal signal peptide structure of the amino acid sequence,neither obvious signal peptide cleavage site nor signal peptide was found,and the protein had no transmembrane region.The amino acid sequence had a N-glycosylation site,4 protein kinase C phosphorylation sites,7 casein kinase II phosphorylation sites,9 N-myristoylation sites,4 isoprene binding sites,10 microbody C-terminal target signal sites,and an ATP/GTP binding site motif A(P-ring).The amino acid sequence of hcp gene of A.hydrophila was performed homology analysis with other Aeromonas strains,and it showed higher homology with A.veronii.In the secondary structure,theα-helix,β-sheet,random coil and extended strand accounted for 45.36%,6.01%,37.52%and 11.11%,respectively.The tertiary structure model consisted of 18α-helix and 22β-sheet.Analysis of protein-protein network interaction demonstrated that the proteins interacting with Hcp protein were AHA_3407,nrfA,nirB-1,nirB-2 and AHA_1112.[Conclusions]Through the bioinformatics prediction results,the basic information of hcp gene of A.hydrophila is preliminarily understood,and the possible function of this protein is predicted,in order to provide guidance for subsequent vaccine research. | Fan LI Xingjun FU Haiyun FENG Shi WANG Weijie ZHANG Huanying PANG Na WANG | 2024 | Asian Agricultural Research2024，16，3： | 0 |
| 6 | A Deep Learning-Based Teaching Design for High School Geography Units:Taking the Example of Landforms of the Humanistic Education Edition显示文摘The traditional teaching methods of one-way cultivation of students can no longer meet the requirements of talent cultivation at this stage.The issue of how to promote students from passive acceptance to the independent cognitive understanding stage(i.e.deep learning)has become the focus of geography teaching.Therefore,under the guidance of deep learning theory,this paper takes the“landforms”knowledge unit of the Humanistic Education Edition as an example,improves the classroom teaching means through the unit teaching mode,reconstructs the“landforms”teaching unit,and explores the specific teaching of high school geography unit based on deep learning.This study provides a good example and guidelines for high school geography teaching and learning. | Xiaojie Yuan Chenguang Zhang Jiajia Li Jiqiang Niu Xiumei Li Xingjun Shi | 2024 | Journal of Contemporary Educational Research2024，8，2： | 0 |
| 7 | Characterization and modeling studies towards Al_(3)Ti/Mg interfaces in Ti reinforced AZ31 alloys显示文摘The interfaces between in-situ Al3Ti particles and magnesium(Mg)matrix are crucial role in highperformance titanium(Ti)reinforced AZ31 alloy.Herein,the interfaces between Al3Ti particles and the Mg matrix are fabricated and investigated using advanced characterization tools and first-principles calculations.The orientation relationship(OR)and atomic interface structure between the Al_(3)Ti particles and matrix are characterized using a high-resolution transmission electron microscope.The OR is determined to be(1010)Mg//(001)Al3Ti;[1213]Mg//[100]Al3Ti.Based on the characterized OR,the interface properties(including atomic structure,work of adhesion,interface energy,and fracture mechanism)are investigated using first-principles calculations.The relaxed interface structure indicates that the TiAl-terminated bridge site configurations(MT1)and hollow site configurations(HCP1)are unstable and would convert into other bridge site configurations(MT).Furthermore,the work of adhesion and interface energy suggests that Al-terminated hollow site configurations(HCP)and bridge site configurations(MT)are more stable than other configurations.In addition,the calculations of work of fracture show that fracture of the interfaces with Al-MT1,Al-HCP,and TiAl-MT configurations may initiate from bulk Mg interior.The findings may help to understand and tailor the deformation mechanisms and mechanical properties of Ti-reinforced Mg alloys. | Longke Bao Shengli Han Shengkun Xi Yuhui Zhang Cuiping Wang Kaihong Zheng Rongpei Shi Xingjun Liu Fusheng Pan | 2023 | Journal of Materials Science & Technology2023，，16： | 0 |
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