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| 1 | Near-surface sand-dust horizontal flux in Tazhong-the hinterland of the Taklimakan Desert显示文摘Tazhong is the hinterland and a sandstorm high-frequency area of the Taklimakan Desert. However, little is known about the detailed time-series of aeolian sand transport in this area. An experiment to study the sand-dust horizontal flux of near-surface was carried out in Tazhong from January to December 2009. By measuring the sand-dust horizontal flux throughout sixteen sand-dust weather processes with a 200-cm tall Big Spring Number Eight (BSNE) sampler tower, we quantitatively analyzed the vertical variation of the sand-dust horizontal flux. And the total sand-dust horizontal flux of different time-series that passed through a section of 100 cm in width and 200 cm in height was estimated combining the data of saltation movement continuously recorded by piezoelectric saltation sensors (Sensit). The results indicated that, in the surface layer ranging from 0-200 cm, the intensity of sand-dust horizontal flux decreased with the increase of the height, and the physical quantities obeyed power function well. The total sand-dust horizontal flux of the sixteen sand-dust weather processes that passed through a section of 100 cm in width and 200 cm in height was about 2,144.9 kg, the maximum of one sand-dust weather event was about 396.3 kg, and the annual total sand-dust horizontal flux was about 3,903.2 kg. The high levels of aeolian sand transport occurred during daytime, especially from 13:00 to 16:00 in the afternoon. We try to develop a new method for estimation of the detailed time-series of aeolian sand transport. | XingHua YANG Qing HE Mamtimin ALI Wen HUO XinChun LIU | 2013 | Journal of Arid Land2013，5，2： | 11 |
| 2 | Platelet function monitoring guided antiplatelet therapy in patients receiving high-risk coronary interventions显示文摘 | Xu Li Wang Lefeng Yang Xinchun Li Kuibao Sun Hao Zhang Dapeng Wang Hongshi Li Weiming Ni Zhuhua Xia Kun Liu Yu | 2014 | Chinese Medical Journal2014，，19： | 8 |
| 3 | Polybrominated diphenyl ethers in soil from three typical industrial areas in Beijing, China显示文摘Areas containing industrial facilities belonging to three diferent typical industries that may cause pollution by polybrominated diphenyl ethers(PBDEs) in Beijing, China were investigated. Specifically, the areas contained a solid waste incineration plant, a chemical factory, and a heat and power plant. Investigation of the pollution status of PBDEs in the surface soil from areas around these industries revealed the highest concentration of 42 PBDE congeners(118 ng/g, dry mass) at the solid waste incineration plant. In the other two plants, the highest concentrations were both 26 ng/g(dry mass). Among the PBDE homologues, the PBDE contamination at all sites showed similar congener compositions, with BDE 209 being the dominant congener. Our findings established the first contamination status of three typical industrial areas in Beijing. Furthermore, the total concentrations of 42 PBDE congeners tended to decrease as the distance from the investigated plants increased. Overall, these plants were identified as potential pollution sources of PBDEs in Beijing. Moreover, Pearson correlation analysis revealed that the major PBDE source in Beijing may be associated with the technical deca-BDE and penta-BDE mixture. Based on the data obtained in this preliminary investigation, further study of the potential of these sources to emit PBDEs in Beijing is warranted. | Yongfei Zhang Shan Fu Xinchun Liu Zheng Li Yuan Dong | 2013 | Journal of Environmental Sciences2013，25，12： | 7 |
| 4 | Research on effectiveness of coal mine safety supervision system reform on three types of collieries in China显示文摘Coal mine safety supervision system plays an important role in the coal mine safety management in China.However,the current supervision system is established on the basis of learning the advanced experience from other developed countries.It needs to be further improved according to national conditions.Therefore,the effectiveness of coal mine safety supervision system reform on three types of collieries are assessed by using time series analysis method based on comparative analysis of the supervision system before and after the reform in this paper.The regression results show that the structural reform is not conductive to the improvement of coal mine safety situation in the short term,but conductive significantly in the long term.Specifically,the effects in township coal mines are more significant than stateowned key coal mines in the long run,but negative effects also exist in the short term.The negative effects in state-owned key coal mines are non-significant compared with township coal mines.Moreover,the regression results are analyzed from the aspects of the closure policy of illegal small township coal mines at the end of 1998 and shortage of the new supervision system.Finally,the suggestions on improving the new supervision system are put forward based on the above analysis. | Quanlong Liu Xinchun Li Fuyuan Guan | 2014 | International Journal of Coal Science & Technology2014，1，3： | 7 |
| 5 | Co-infections of SARS-CoV-2 with multiple common respiratory pathogens in infected patients显示文摘Dear Editor,In late December 2019,an outbreak of severe pneumonia caused by an unknown etiological agent was initially reported in Wuhan,China,and then quickly spread throughout China and even abroad(Zhu et al.,2020).Swift control measures and etiological investigations were conducted by the Chinese government,physicians and researchers,and by using high throughput sequencing and virological testing,the mysterious pneumonia pathogen was shown to be a novel coronavirus(SARS-CoV-2)capable of person-to-person transmission(Zhu et al.,2020).Coronaviruses are a group of non-segmented,enveloped and positive-sense RNA viruses that belong to the subfamily of Coronavirinae in the family of Coronavirdiae and order of Nidovirales. | Dachuan Lin Lei Liu Mingxia Zhang Yunlong Hu Qianting Yang Jiubiao Guo Yongchao Guo Youchao Dai Yuzhong Xu Yi Cai Xinchun Chen Zheng Zhang Kaisong Huang | 2020 | Science China(Life Sciences)2020，63，4： | 6 |
| 6 | Study of lubrication behavior of pure water for hydrophobic friction pair显示文摘The perfluorooctyltrichlorosilane molecular layer was self-assembled on glass plate. The tribological properties of the molecular layer in water were studied with the method of ball on disk. An interesting phenomenon was found that low friction coefficients of 0.02―0.08 were obtained when the friction pair was lubricated with only a water droplet. Whereas, when the friction pair was encircled with large amount of water or fully immersed in water, the friction coefficient was higher than that under a droplet lubrication. A mechanism of water droplet lubrication was proposed that the surface tension caused by the solid-liquid-air three-phase interface makes water molecules enter into the contact zone, which separates the two friction surfaces and provides a low friction coefficient. However, water film can hardly form when more water encircles the friction pair, due to the attraction between water molecules. | MA ZhiZuo ZHANG ChenHui LIU ShuHai LUO JianBin LU XinChun WEN ShiZhu | 2009 | Science China(Technological Sciences)2009，52，11： | 4 |
| 7 | Vertical distribution characteristics of dust aerosol mass concentration in the Taklimakan Desert hinterland显示文摘The different height mass concentrations of dust aerosol data from the atmosphere environment observation station(Tazhong Station)was continuously observed by instruments of Grimm 1.108,Thermo RP 1400a and TSP from January of2009 to February of 2010 in the Taklimakan Desert hinterland.Results show that:(1)The mass concentration value of 80m PM10was higher,but PM2.5and PM1.0concentrations at 80 m was obviously lower than 4 m PM10,and the value of 80 m PM1.0mass concentration was the lowest.(2)The PM mass concentrations gradually decreased from night to sunrise,with the lowest concentration at 08:00,with the mass concentration gradually increased,up to the highest concentration around18:00,and then decreased again.It was exactly the same with the changes of wind speed.(3)The high monthly average mass concentration of TSP mainly appeared from March to September,and the highest concentration was in April and May,subsequently gradually decreased.Also,March–September was a period with high value area of PM monthly average mass concentration,with the highest monthly average mass concentration of 846.0μg/m3for 4 m PM10appeared in May.The concentration of PM10was much higher than those of PM2.5and PM1.0at 80 m.There is a small difference between the concentration of PM2.5and PM1.0.Dust weather was the main factor which influenced the concentration content of the different diameter dust aerosol,and the more dust weather days,the higher content of coarse particle,conversely,fine particle was more.(4)The mass concentration of different diameter aerosols had the following sequence during dust weather:clear day | XinChun Liu YuTing Zhong Qing He XingHua Yang Ali Mamtimin Wen Huo | 2013 | Research in Cold and Arid Regions2013，5，6： | 3 |
| 8 | Achievement of a near-perfect smooth silicon surface显示文摘During the ultra large scale integration(ULSI)process,the surface roughness of the polished silicon wafer plays an important role in the quality and rate of production of devices.In this work,the effects of oxidizer,surfactant,polyurethane pad and slurry additives on the surface roughness and topography of chemical-mechanical planarization(CMP)for silicon have been investigated.A standard atomic force microscopy(AFM)test method for the atomic scale smooth surface was proposed and used to measure the polished silicon surfaces.Finally,compared with the theoretical calculated Ra value of 0.0276 nm,a near-perfect silicon surface with the surface roughness at an atomic scale(0.5)was achieved based on an optimized CMP process. | LI Jing LIU YuHong DAI YuanJing YUE DaChuan LU XinChun LUO JianBin | 2013 | Science China(Technological Sciences)2013，56，11： | 3 |
| 9 | Experimental investigation of high temperature thermal contact resistance with interface material显示文摘Thermal contact resistance plays a very important role in heat transfer efficiency and thermomechanical coupling response between two materials,and a common method to reduce the thermal contact resistance is to fill a soft interface material between these two materials.A testing system of high temperature thermal contact resistance based on INSTRON 8874 is established in the present paper,which can achieve 600 C at the interface.Based on this system,the thermal contact resistance between superalloy GH600 material and three-dimensional braid C/C composite material is experimentally investigated,under different interface pressures,interface roughnesses and temperatures,respectively.At the same time,the mechanism of reducing the thermal contact resistance with carbon fiber sheet as interface material is experimentally investigated.Results show that the present testing system is feasible in the experimental research of high temperature thermal contact resistance. | Xiaoping Zheng1,Donghuan Liu,2,3 Dong Wei,4 and Xinchun Shang 2,3 1) Applied Mechanics Laboratory,Department of Engineering Mechanics,Tsinghua University,Beijing 100084,China 2) Department of Applied Mechanics,University of Science & Technology Beijing,Beijing 100083,China 3) National Center for Materials Service Safety,University of Science & Technology Beijing,Beijing 100083,China 4) China Aerodynamics Research and Development Center,Mianyang 621000,China | 2011 | Theoretical & Applied Mechanics Letters2011，1，5： | 3 |
| 10 | Analysis of mass concentration of atmospheric particulate matter in a sandstorm course and its affecting factors in the Taklimakan Desert显示文摘During the course of a major sandstorm from April 17 to April 23,2008 in the Taklimakan Desert,data pertaining to the mass concentrations of different-sized atmospheric particulate matter were observed continuously with Grimm 1.108,Thermo RP 1400a,TSP,and CAWS-600 instruments.The results showed that:(1) during the entire sandstorm process there were some differences between the daily mean particle concentration peaks and the hourly mean particle concentration peaks because the actual sandstorm lasted for only about 4 hr,whereas more particles were accumulated in the floating dust days before and after the actual sandstorm;(2) the intensity of the sandstorm was enhanced with the increase of wind speed,and this was related to the peak mass concentrations of atmospheric particulate matter;the wind speed directly affected the concentration of atmospheric particulate matter:the higher the wind speed,the higher the mass concentration(>0.23 μm was 39,496.5 μg/m 3,and >20.0 μm was 5,390.7 μg/m 3);(3) the concentration changes of PM 10 and TSP were also related to the course and intensity of the sandstorm;and(4) the mass concentration of atmospheric particulate matter had the following sequence during the dust weather:clear day < floating dust < floating and blowing dust < sandstorm.Temperature,relative humidity,and barometric pressure are important factors affecting the strength of storms,which could also indirectly affect the concentration change of atmospheric particulate matter. | XinChun Liu YuTing Zhong Qing He XingHua Yang Ali Mamtimin Wen Huo | 2012 | Research in Cold and Arid Regions2012，4，3： | 3 |
| 11 | Long noncoding RNA(lncRNA)HOTAIR:Pathogenic roles and therapeutic opportunities in gastric cancer显示文摘Gastric cancer is one of the first malignant cancers in the world and a large number of people die every year due to this disease.Many genetic and epigenetic risk factors have been identified that play a major role in gastric cancer.HOTAIR is an effective epigenetic agent known as long noncoding RNA(lncRNA).HOTAIR has been described to have biological functions in biochemical and cellular processes through interactions with many factors,leading to genomic stability,proliferation,survival,invasion,migration,metastasis,and drug resistance.In the present article,we reviewed the prognostic value of the molecular mechanisms underlying the HOTAIR regulation and its function in the development of Gastric Cancer,whereas elucidation of HOTAIR–protein and HOTAIR–DNA interactions can be helpful in the identification of cancer processes,leading to the development of potential therapeutic strategies. | Wencheng Kong Guang Yin Sixin Zheng Xinchun Liu Akao Zhu Panpan Yu Jian Zhang Yuqiang Shan Rongchao Ying Huicheng Jin | 2022 | Genes & Diseases2022，9，5： | 3 |
| 12 | The association between metabolic abnormality and endometrial cancer: A large case-control study in China显示文摘 | Yan Zhang Zhiwei Liu Xinchun Yu Xiaofei Zhang Shiming Lü Xiaoduan Chen Bingjian Lü | 2010 | Gynecologic Oncology2010，，1： | 3 |
| 13 | Tunable tribological properties in water-based lubrication of water-soluble fullerene derivatives via varying terminal groups显示文摘In this paper,three kinds of water-soluble fullerene derivatives were synthesized via electrophilic addition reaction and cycloaddition reaction,respectively.The chemical composition characterizations of these derivatives indicated the successful preparation of C60(OH)x,C60(C(COOH)2)x and C60(OH)x(NHCH2COOH)y fullerene derivatives.The aggregation and morphology characterizations showed that the three kinds of derivatives had an ideal spherical aggregating structures and excellent dispersibility in water,especially C60(OH)x and C60(C(COOH)2) x.The lubrication performance of the fullerene derivatives acted as lubricant additives were investigated at different concentrations in the range of 0-1 wt%.The results indicated that the addition of polyhydroxyl and carboxylic derivatives could improve the lubrication properties,which led to the reduction of wear to about 40% at most.It is attributed that the optimized substitutions of fullerene molecules may be of benefit to their distribution properties and lubricating behaviors in water based lubrication. | LIU YuHong LIU PengXiao CHE Lu SHU ChunYing LU XinChun | 2012 | Chinese Science Bulletin2012，57，35： | 3 |
| 14 | Influence of tribofilm on superlubricity of highly-hydrogenated amorphous carbon films in inert gaseous environments显示文摘In this study,we mainly focus on the structural morphology and inter-atomic bonding state of tribofilms resulting from a highly-hydrogenated amorphous carbon(a-C:H) film in order to ascertain the underlying mechanisms for its superlubric behavior(i.e.,less than 0.01 friction coefficient).Specifically,we achieved superlubricity(i.e.,friction coefficients of down to 0.003) with this film in dry nitrogen and argon atmospheres especially when the tribo-pair is made of an a-C:H coated Si disk sliding against an a-C:H coated steel ball,while the a-C:H coated disk against uncoated ball does not provide superlubricity.We also found that the state of superlubricity is more stable in argon than in nitrogen and the formation of a smooth and uniformly-thick carbonaceous tribofilm appears to be one of the key factors for the realization of such superlubricity.Besides,the interfacial morphology of sliding test pairs and the atomic-scale bond structure of the carbon-based tribofilms also play an important role in the observed superlubric behavior of a-C:H films.Using Raman spectroscopy and high resolution transmission electron microscopy,we have compared the structural differences of the tribofilms produced on bare and a-C:H coated steel balls.For the a-C:H coated ball as mating material which provided superlow friction in argon,structural morphology of the tribofilm was similar or comparable to that of the original a-C:H coating;while for the bare steel ball,the sp^2-bonded C fraction in the tribofilm increased and a fingerprint-like nanocrystalline structure was detected by high resolution transmission electron microscopy(HRTEM).We also calculated the shear stresses for different tribofilms,and established a relationship between the magnitude of the shear stresses and the extent of sp^3-sp^2 phase transformation. | LIU ShuWei ZHANG ChenHui OSMAN Eryilmaz CHEN XinChun MA TianBao HU YanZhong LUO JianBin ALI Erdemir | 2016 | Science China(Technological Sciences)2016，59，12： | 2 |
| 15 | Identification of a potential tumor suppressor gene, UBL3, in non-small cell lung cancer显示文摘Objective: Oncogenes have been shown to be drivers of non-small cell lung cancer(NSCLC), yet the tumor suppressing genes involved in lung carcinogenesis remain to be systematically investigated. This study aimed to identify tumor suppressing ubiquitin pathway genes(UPGs) that were critical to lung tumorigenesis.Methods: The 696 UPGs were silenced by an siRNA screening in NSCLC cells;the potential tumor suppressing UPGs were analyzed, and their clinical significance was investigated.Results: We reported that silencing of 11 UPGs resulted in enhanced proliferation of NSCLC cells, and four UPGs(UBL3, TRIM22, UBE2 G2, and MARCH1) were significantly downregulated in tumor samples compared to that in normal lung tissues and their expression levels were positively associated with overall survival(OS) of NSCLC patients. Among these genes, UBL3 was the most significant one. UBL3 expression was decreased in tumor samples compared to that in paired normal lung tissues in 59/86(68.6%) NSCLCs, was correlated with TNM stage and sex of NSCLC patients, and was significantly higher in non-smoking patients than in smoking patients. Silencing UBL3 accelerated cell proliferation and ectopic expression of UBL3 suppressed NSCLC in vitro and in vivo.Conclusions: These results showed that UBL3 represented a tumor suppressor in NSCLC and may have potential for use in therapeutics and for the prediction of clinical outcome of patients. | Xinchun Zhao Yongchun Zhou Qian Hu Sanhui Gao Jie Liu Hong Yu Yanfei Zhang Guizhen Wang Yunchao Huang Guangbiao Zhou | 2020 | Cancer Biology & Medicine2020，17，1： | 2 |
| 16 | A murine model for human immune thrombocytopenic purpura and comparative analysis of multiple gene expression in bone marrow and spleen显示文摘Homeostasis of platelet number in human and other mammals is well maintained for prevention of minor bleeding and for other immunological functions,but the exact molecular mechanism responsible for immune thrombocytopenic purpura(ITP) has not been fully understood.In an effort to identify genetic factors involved in initiation of platelet production in response to bleeding injury or platelet destruction,we have successfully generated an animal model of human ITP via intraperitoneal injection of anti-platelet antibody into the Balb/c mouse.Platelet counts were dropped dramatically in animals that received antibody injection within 4 h,maintained at the mini-mum level for a period of 44 h,started to rebound after 48 h,and reached to the maximum at 144 h(6 days).Final homeostasis reached at approximately 408 h(17 days),following a minor cycle of platelet number fluctuation.Using semi-quantitative RT-PCR,we assessed and compared mRNA level of CD41,c-myb,c-mpl,caspase-3,caspase-9,GATA-1,and Bcl-xl in bone marrow and spleen.Alteration of mRNA expression was correlated with the change of platelet level,and an inverse relationship was found for expression of the genes between bone marrow and spleen.No transcription was detectable for any of the seven genes in bone marrow at the time when platelet number reached the maximum(144 h).In contrast,mRNA transcripts of the seven genes were found to be at the highest level in spleen tissue.This is the first study of simultaneous detection of multiple platelet related genes in a highly reproducible ITP animal model.Our results provided the supportive evidence that expression of the above seven genes are more related to negative regulation of platelet number in spleen tissue,at least in the model animals. | Hong Wei Xinchun Ding Jiangong Ren Ka Liu Pingping Tan Daquan Li Runlin Z. Ma | 2008 | Journal of Genetics and Genomics2008，35，11： | 2 |
| 17 | Modified ADM1 for modeling free ammonia inhibition in anaerobic acidogenic fermentation with high-solid sludge显示文摘Anaerobic acidogenic fermentation with high-solid sludge is a promising method for volatile fatty acid(VFA) production to realize resource recovery. In this study, to model inhibition by free ammonia in high-solid sludge fermentation, the anaerobic digestion model No. 1(ADM1) was modified to simulate the VFA generation in batch, semicontinuous and full scale sludge. The ADM1 was operated on the platform AQUASIM 2.0.Three kinds of inhibition forms, e.g., simple inhibition, Monod and non-inhibition forms,were integrated into the ADM1 and tested with the real experimental data for batch and semi-continuous fermentation, respectively. The improved particle swarm optimization technique was used for kinetic parameter estimation using the software MATLAB 7.0. In the modified ADM1, the Ksof acetate is 0.025, the km,acis 12.51, and the KI_NH3is 0.02,respectively. The results showed that the simple inhibition model could simulate the VFA generation accurately while the Monod model was the better inhibition kinetics form in semi-continuous fermentation at p H 10.0. Finally, the modified ADM1 could successfully describe the VFA generation and ammonia accumulation in a 30 m3full-scale sludge fermentation reactor, indicating that the developed model can be applicable in high-solid sludge anaerobic fermentation. | Jie Bai He Liu Bo Yin Huijun Ma Xinchun Chen | 2017 | Journal of Environmental Sciences2017，29，2： | 1 |
| 18 | The Influence of Cell Micro-to- Pology on the In-Plane Dynamic is Crushing of Honeycombs 显示文摘 | Liu Ying Zhang Xinchun | 2009 | International Journal of Impact Engineering2009，36，1： | 1 |
| 19 | Application of wind profiler data to rainfall analyses in Tazhong Oilfield region,Xinjiang,China显示文摘To improve the level of meteorological service for the Oilfield region in the Taklimakan Desert,the Urumqi Institute of Desert Meteorology of the China Meteorological Administration(CMA) conducted a detection experiment by means of wind profiling radar(WPR) in Tazhong Oilfield region of Xinjiang,China in July 2010.By using the wind profiler data obtained during the rainfall process on 27 July,this paper analyzed the wind field features and some related scientific issues of this weather event.The results indicated that:(1) wind profiler data had high temporal resolution and vertical spatial resolution,and could be used to analyze detailed vertical structures of rainfall processes and the characteristics of meso-scale systems.Before and after the rain event on 27 July,the wind field showed multi-layer vertical structures,having an obvious meso-scale wind shear line and three airflows from different directions,speeding up the motion of updraft convergence in the lower atmosphere.Besides,the wind directions before and after the rainfall changed inversely with increasing height.Before the rain,the winds blew clockwise,but after the onset of the rain,the wind directions became counterclockwise mainly;(2) the temperature advection derived from wind profiler data can reproduce the characteristics of low-level thermodynamic evolution in the process of rainfall,which is capable to reflect the variation trend of hydrostatic stability in the atmosphere.In the early stage of the precipitation on 27 July,the lower atmosphere was mainly affected by warm advection which had accumulated unstable energy for the rainfall event and was beneficial for the occurrence of updraft motion and precipitation;(3) the 'large-value zone' of the radar reflectivity factor Z was virtually consistent with the onset and end of the rainfall,the height for the formation of rain cloud particles,and precipitation intensity.The reflectivity factor Z during this event varied approximately in the range of 18-38 dBZ and the rain droplets formed mainly at the layer of 3,800-4,500 m. | MinZhong WANG WenShou WEI Qing HE XinChun LIU ZhongJie ZHAO | 2012 | Journal of Arid Land2012，4，4： | 1 |
| 20 | Doctor–patient communication skills training in mainland China: A systematic review of the literature显示文摘 | Xinchun Liu Wesley Rohrer Aijing Luo Zhou Fang TianHua He Wenzhao Xie | 2014 | Patient Education and Counseling2014，，： | 1 |
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