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| 1 | Relationship between full-thickness macular hole and retinal break/lattice degeneration显示文摘Background: The purpose is to investigate the relationship between full-thickness macular hole(MH) and retinal break(RB) and/or lattice degeneration.Methods: Patients diagnosed as full-thickness MH and referred to Dr. Lin Lu from January 2009 to December 2013 were evaluated. All patients underwent general ophthalmologic examinations, fundus examination and optical coherence tomography(OCT). The RB and/or lattice degeneration were recorded.Results: Totally 183 eyes of 167 patients were included. The sex ratio of men to women was 1:2.88. A total of 17 eyes were pseudophakic and 166 eyes were phakic. RB and/or lattice degeneration were found in 62 eyes(33.88%). The prevalence of RB and/or lattice degeneration was similar between men and women(P=0.344>0.05). There was no statistical difference between the pseudophakic eyes and phakic eyes(P=0.138>0.05). All of the RB and/or lattice degeneration were located near or anterior to the equator. The inferior quadrants and the vertical meridian were af ected more often than the superior quadrants and the horizontal meridian.Conclusions: We identified a high incidence of RB/lattice degeneration in cases of full-thickness MH. Carefully examination of the peripheral retina and prophylactic treatment of RB and/or lattice degeneration are critical. | Jinglin Zhang Yonghao Li Xiujuan Zhao Yu Cai Xiling Yu Lin Lu | 2015 | Eye Science2015，30，4： | 2 |
| 2 | Technological Exploration of RRAM Crossbar Array for Matrix-Vector Multiplication显示文摘矩阵向量增加是为许多计算地集中的算法的关键操作。抵抗切换的随机的存取存储器(RRAM ) 设备和 RRAM 闩穿的新兴的金属氧化物表明了模拟矩阵向量增加的一条有希望的硬件认识与超离频精力效率。在这篇论文,我们分析设备水平和电路水平的影响非理想的因素包括 RRAM 设备的非线性的当前电压的关系,设备制造的变化并且给操作,和 interconnect 抵抗以及另外的闩数组写参数。在那上,我们建议工艺的探索流动让设备参数配置克服非理想的因素的影响并且为各特定的申请在性能,精力,和可靠性之中完成一宗更好的交易。我们向量机器(SVM ) 和混合公民标准和技术(MNIST ) 模式识别数据集开创的支持的模拟结果证明那个 RRAM 闩数组基于 SVM 是柔韧的输入信号变化但是对通道差距偏差敏感。进一步的抵抗决定测试一台 6 位的 RRAM 设备对有能力的礼品在 90% 附近认识到识别精确性,显示 RRAM 闩数组的物理可行性基于 SVM。另外,建议工艺的探索流动能与以前的工作相比在 MNIST 数据集和 26.4% 精力积蓄上完成识别精确性的 10.98% 改进。试验性的结果也证明节省的超过 84.4% 力量能以很少精确性减小的成本被完成。 | Lixue Xia Peng Gu Boxun Li Tianqi Tang Xiling Yin Wenqin Huangfu Shimeng Yu Yu Cao Yu Wang Huazhong Yang | 2016 | Journal of Computer Science & Technology2016，31，1： | 2 |
| 3 | Chromosome-level Genomes Reveal the Genetic Basis of Descending Dysploidy and Sex Determination in Morus Plants显示文摘Multiple plant lineages have independently evolved sex chromosomes and variable karyotypes to maintain their sessile lifestyles through constant biological innovation.Morus notabilis,a dioecious mulberry species,has the fewest chromosomes among Morus spp.,but the genetic basis of sex determination and karyotype evolution in this species has not been identified.In this study,three high-quality genome assemblies were generated for Morus spp.[including dioecious M.notabilis(male and female)and Morus yunnanensis(female)]with genome sizes of 301–329 Mb and were grouped into six pseudochromosomes.Using a combination of genomic approaches,we found that the putative ancestral karyotype of Morus species was close to 14 protochromosomes,and that several chromosome fusion events resulted in descending dysploidy(2n=2x=12).We also characterized a~6.2-Mb sex-determining region on chromosome 3.Four potential male-specific genes,a partially duplicated DNA helicase gene(named MSDH)and three Ty3_Gypsy long terminal repeat retrotransposons(named MSTG1/2/3),were identified in the Y-linked area and considered to be strong candidate genes for sex determination or differentiation.Population genomic analysis showed that Guangdong accessions in China were genetically similar to Japanese accessions of mulberry.In addition,genomic areas containing selective sweeps that distinguish domesticated mulberry from wild populations in terms of flowering and disease resistance were identified.Our study provides an important genetic resource for sex identification research and molecular breeding in mulberry. | Zhongqiang Xia Xuelei Dai Wei Fan Changying Liu Meirong Zhang Peipei Bian Yuping Zhou Liang Li Baozhong Zhu Shuman Liu Zhengang Li Xiling Wang Maode Yu Zhonghuai Xiang Yu Jiang Aichun Zhao | 2022 | Genomics, Proteomics & Bioinformatics2022，20，6： | 1 |
| 4 | The nature of the potentiostatic current oscillations at iron/sulfuric acid solution interfaces 显示文摘 | Chao Wang Shenhao Chen Xiling Yu | 1994 | Electrochimica Acta1994，39，4： | 1 |
| 5 | Growth of Cadmium Mercury Thiocyanate Dimethyl-sulphoxide Single Crystal for Laser Frequency Doubling显示文摘 | Guo Shiyi Yuan Duorong Xu Dong Zhang Guanghui Sun Suoying Meng Fanqing Wang Xinqiang Jiang Xuening Jiang Minhua Sun Daliang Yu Xiling | 2000 | Progress in Crystal Growth and Characterization of Materials2000，，： | 1 |
| 6 | Licochalcone A inhibiting proliferation of bladder cancer T24 cells by inducing reactive oxygen species production显示文摘 | Feng Liu Ali Goodarzi Haifeng Wang Joanna Stasiak Jianbo Sun Yu Zhou Jiangtao Jiang Xuan Yuan Hong Zhao Xinyan Yan Xiling Sun Qiusheng Zheng | 2014 | Bio-Medical Materials and Engineering2014，，1： | 1 |
| 7 | Case 02-2017-Discussion of clinical pearls derived from 4 challenging and unusual retinal cases显示文摘Four challenging and unusual retinal cases:(I)11-year follow-up for retinal hemangioblastoma with von Hippel-Lindau(VHL)disease;(II)treatment for central serous chorioretinopathy(CSC)-observation,half does photodynamic therapy(PDT)or micropulse laser photocoagulation;(III)diagnosis and treatment for a child with optic nerve defect;(IV)the optional treatment for retinal detachment(RD)with iridolenticular choroidal coloboma,were presented and discussed by three international retinal specialists at a retinal clinical round in Fundus Diseases Center of Zhongshan Ophthalmic Center(ZOC).The discussion helps us a better understanding of the pathogenesis and managements of these four retinal diseases and their association with systemic conditions. | Yongsheng Huang Lijun Zhou Yuxin Yuan Xiling Yu Zhengjie Xu Jie Hu Tao Li Lin Lu Chenjin Jin Xiaoling Liang | 2017 | Annals of Eye Science2017，，1： | 0 |
| 8 | Photofragment translational spectroscopy of ICl near 304 and 280 nm: Observation of an intense hot band effect显示文摘The photodissociation dynamics of ICl has been studied near 304 and 280 nm on a simple miniature time of flight (mini-TOF) photofragment translational spectrometer with a short pulse of a weak acceleration field. An intense hot band effect was observed. Many small peaks were resolved in each photofragment translational spectrum (PTS). Based on simulations, the principal peaks were assigned not only to the different photodissociation channels (1) I + Cl, (2) I + Cl*, (3) I* + Cl, or (4) I* + Cl*, but also to the different chlorine isotopes (35Cl and Cl). Moreover, some extra peaks showed the existence of an intense hot 37 band effect from vibrationally excited ICl molecules, though only a few percent of ICl molecules remained in the vibrationally excited states in our supersonic molecular beam. Based on the spectra near 304 nm, the quantum yield Ф of each channel, the curve crossing, and the branching fraction σ from each transition state were determined. | CHENG Min YU ZiJun XU XiLing YU Dan DU YiKui ZHU QiHe | 2012 | Science China Chemistry2012，55，6： | 0 |
| 9 | Genome transfer for the prevention of female infertility caused by maternal gene mutation显示文摘Poor oocyte quality is associated with early embryo developmental arrest and infertility.Maternal gene plays crucial roles in the regulation of oocyte maturation,and its mutation is a common cause of female infertility.However,how to improve oocyte quality and develop effective therapy for maternal gene mutation remains elusive.Here,we use Zar1 as an example to assess the feasibility of genome transfer to cure maternal gene mutationecaused female infertility.We first discover that cytoplasmic deficiency primarily leads to Zar1-null embryo developmental arrest by disturbing maternal transcript degradation and minor zygotic genome activation(ZGA)during the maternal-zygotic transition.We next perform genome transfer at the oocyte(spindle transfer or polar body transfer)and zygote(early pronuclear transfer or late pronuclear transfer)stages to validate the feasibility of preventing Zar1 mutationecaused infertility.We finally demonstrate that genome transfer either at the oocyte or at the early pronuclear stage can support normal preimplantation embryo development and produce live offspring.Moreover,those pups grow to adulthood and show normal fertility.Therefore,our findings provide an effective basis of therapies for the treatment of female infertility caused by maternal gene mutation. | Dandan Bai Jin Sun Yanping Jia Jiqing Yin Yalin Zhang Yanhe Li Rui Gao Xiling Du Kunming Li Jiaming Lin Zhifen Tu Yu Wang Jiaping Pan Shanshan Liang Yi Guo Jingling Ruan Xiaochen Kou Yanhong Zhao Hong Wang Cizhong Jiang Fengchao Wang Xiaoming Teng Wenqiang Liu Shaorong Gao | 2020 | Journal of Genetics and Genomics2020，47，6： | 0 |
| 10 | 4例具有挑战性且不寻常的视网膜病例临床精粹讨论显示文摘3位国际视网膜专家在中山眼科中心(Zhongshan Ophthalmic Center,ZOC)眼底病中心进行临床查房并讨论了4例具有挑战性且不寻常的视网膜病例:1)VHL病合并视网膜血管母细胞瘤的11年随访观察;2)半剂量光动力疗法(photodynamic therapy,PDT)或微脉冲激光光凝治疗中心性浆液性视网膜病变(central serous chorioretinopathy,CSC)的观察;3)视神经缺陷儿童的诊断与治疗;4)合并虹膜晶状体脉络膜缺损的视网膜脱离(retinal detachment,RD)的治疗选择。通过讨论有助于我们更好地了解这四例视网膜疾病的发病机制和治疗方法,及其与全身疾病的关系。 | Yongsheng Huang Lijun Zhou Yuxin Yuan Xiling Yu Zhengjie Xu Jie Hu Tao Li Lin Lu Chenjin Jin Xiaoling Liang 杨玉洁 | 2017 | Eye Science2017，32，4： | 0 |
| 11 | Recent Development on the Mechanism Research of Crystal Growth显示文摘Recent developments on the research of growth mechanism by two -dimensional nucle-ation, dislocation, normal and three -dimensional nucleation are reviewed: the latest research work on the structure adjusting in the interface boundary layers and the theory model of growth units are also summarized in this paper. | Yu Xiling Wan Yan( The State Key Lab of Crystal Materials of Shandong University, Ji ’nan 250100 Physics Department of Shanghai University, Shanghai 200436) | 2002 | Science Foundation in China2002，10，2： | 0 |
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