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| 1 | Effects of Saccharomycesboulardiion fecal short-chain fatty acids and microflora in patients on long-term total enteral nutrition显示文摘AIM: To assess the effects of Sb on fecal flora and shortchain fatty acids (SCFA) in patients on long-term TEN.METHODS: Ten patients (3 females, 7 males, 59±5.5 years),on TEN for a median of 13 mo (1-125), and 15 healthy volunteers (4 females, 11 males, 32±2.0 years) received Sb (0.5 g bid PO) for 6 d. Two stool samples were taken before, on the last 2 d and 9-10 d after treatment, for SCFA measurement and for culture and bacterial identification.Values (mean±SE) were compared using sign tests and ANOVA.RESULTS: Fecal butyrate levels were lower in patients(10.1±2.9 mmol/kg) than in controls (19.2±3.9, P= 0.02).Treatment with Sb increased total fecal SCFA levels in patients (150.2±27.2 vs 107.5±18.2 mmol/kg, P = 0.02)but not in controls (129.0±28.6 vs 113.0±15.2 mmol/kg,NS). At the end of treatment with Sb, patients had higher fecal butyrate (16.0±4.4 vs 10.1 [2.9] mmol/kg, P = 0.004).Total SCFAs remained high 9 d after treatment was discontinued. Before the treatment, the anaerobe to aerobe ratio was lower in patients compared to controls (2.4±2.3 vs69.8±1.8, P = 0.003). There were no significant changes in the fecal flora of TEN patients.CONCLUSION: Sb-induced increase of fecal SCFA concentrations (especially butyrate) may explain the preventive effects of this yeast on TEN-induced diarrhea. | Stéphane M Schneider Fernand Girard-Pipau Jér(o|^)me Filippi Xavier Hébuterne Dominique Moyse Gustavo Calle Hinojosa Anne Pompei Patrick Rampal | 2005 | World Journal of Gastroenterology2005，11，39： | 26 |
| 2 | 睾丸后精子成熟,不育与高胆固醇血症显示文摘胆固醇是参与哺乳动物生理活动的重要分子,由于它是固醇类激素合成的通用前体物质,因而对生殖系统尤为重要。胆固醇不仅仅对于配子发生起到重要作用,它也是公认的精子功能的调节分子。胆固醇体内平衡的调节对睾丸后精子的成熟至关重要,胆固醇水平失衡会影响到睾丸后调控事件。代谢性脂质紊乱(血脂异常症)会影响男性的生育能力,但大多数这方面的研究是从内分泌/睾丸的角度进行探讨的,而这篇综述将关注像高胆固醇血症这样的特定血脂异常症在哺乳动物精子的睾丸后成熟过程中的有害影响。 | Marjorie Whitfield Xavier PoUet-Villard Rachel Levy Joel R Drevet Fabrice Saez | 2015 | Asian Journal of Andrology2015，17，5： | 8 |
| 3 | Prevalence and virological profiles of hepatitis B infection in human immunodeficiency virus patients显示文摘AIM: To determine the prevalence of hepatitis B virus (HBV) in adult human immunodeficiency virus (HIV) patients with CD4+ T-cell count less than 500/mm 3 and without antiretroviral therapy; to describe different HBV-HIV coinfection virological profiles; and to search for factors associated with HBs antigen (HBsAg) presence in these HIV positive patients.METHODS: During four months (June through September 2006), 491 patients were received in four HIV positive monitoring clinical centers in Abidjan. Inclusion criteria: HIV-1 or HIV-1 and 2 positive patients, age ≥ 18 years, CD4+ T-cell count < 500/mL and formal and signed consent of the patient. Realized blood tests included HIV serology, CD4+ T-cell count, quantitative HIV RNA load and HBV serological markers, such as HBsAg and HBc antibody (anti-HBcAb). We performed HBeAg, anti-HBe antibody (anti-HBeAb), anti-HBc IgM and quantitative HBV DNA load in HBsAg positive patients. Anti-HBsAb had been tested in HIV patients with HBsAg negative and anti-HBcAb-positive. HBV DNA was also tested in 188 anti-HBcAb positive patients with HBsAg negative status and without anti-HBsAb. Univariate analysis (Pearsonχ 2 test or Fischer exact test) and multivariate analysis (backward step-wise selection logistic regression) were performed as statistical analysis. RESULTS: Mean age of 491 patients was 36 ± 8.68 years and 73.3% were female. Type-1 HIV was found in 97% and dual-type HIV (type 1 plus type 2) in 3%. World Health Organization (WHO) clinical stage was 1, 2, 3 and 4 respectively in 61 (12.4%), 233 (47.5%), 172 (35%) and 25 patients (5.1%). Median CD4+ T-cell count was 341/mm 3 (interquartile range: 221-470). One hundred and twelve patients had less than 200 CD4+ T-cell/mm 3 . Plasma HIV-1 RNA load was elevated (≥ 5 log 10 copies/mL) in 221 patients (45%). HBsAg and anti-HBcAb prevalence was respectively 13.4% and 72.9%. Of the 66 HBsAg positive patients, 22 were inactive HBV carriers (33.3%), 21 had HBeAg positive hepatitis (31.8%) and 20 had HBeAg negative hepatitis (30.3%). HBeAg and anti-HBeAb were indeterminate in 3 of them. Occult B infection prevalence (HBsAg negative, anti-HBcAb positive, anti-HBsAb negative and detectable HBV DNA) was 21.3%. Three parameters were significantly associated with the presence of HBsAg: male [odds ratio (OR): 2.2;P = 0.005; 95% confidence interval (CI): 1.3-3.8]; WHO stage 4 (OR: 3.2;P = 0.01;95% CI: 1.3-7.9); and aspartate aminotransferase (AST) level higher than the standard (OR: 1.9;P = 0.04; 95% CI: 1.02-3.8). CONCLUSION: HBV infection prevalence is high in HIV-positive patients. HBeAg positive chronic hepatitis and occult HBV infection are more frequent in HIVpositive patients than in HIV negative ones. Parameters associated with HBsAg positivity were male gender, AIDS status and increased AST level. | Koffi Alain Attia Serge Eholié Eugène Messou Christine Danel Sandrine Polneau Henri Chenal Thomas Toni Myreille Mbamy Catherine Seyler Naomi Wakasugi Thérèse N'dri-Yoman Xavier Anglaret | 2012 | World Journal of Hepatology2012，4，7： | 4 |
| 4 | 焊接参数对搅拌摩擦焊接AA2219-T87材料韧性、洋葱圆环的断裂行为的影响(英文)显示文摘与熔焊相比,搅拌摩擦焊可以更好地保持材料的韧性和塑性,提高焊接的抗裂稳定性。本研究旨在提高焊接接头的延性和强度。刀具廓形在保持延性、分析金属流动行为和确定断裂起始点等方面起着重要作用。分析了洋葱圆环不同区域的微观结构,得出了洋葱圆环强度与金属流型的关系。结果表明,洋葱圆环强化了焊缝熔核。肩部和锥形螺纹型线刀具具有优异的力学性能。显微硬度数据表明,断口经过热影响区和热机械影响区等低硬度区。扫描电镜图像显示了细长的晶粒和韧窝,证实了断裂为韧性断裂。 | Dinesh KUMAR R S MUTHUKUMARAN Vincent XAVIER T VENKATESWARAN D SIVAKUMAR | 2019 | Journal of Central South University2019，26，9： | 2 |
| 5 | Paraffin/porous-graphite-matrix composite as a high and constant power thermal storage material显示文摘 | Xavier Py Régis Olives Sylvain Mauran | 2001 | International Journal of Heat and Mass Transfer2001，，14： | 2 |
| 6 | Folic acid supplementation, MTHFR and MTRR polymorphisms, and the risk of childhood leukemia: the ESCALE study (SFCE)显示文摘 | Alicia Amigou Jérémie Rudant Laurent Orsi Stéphanie Goujon-Bellec Guy Leverger André Baruchel Yves Bertrand Brigitte Nelken Geneviève Plat Gérard Michel Stéphanie Haouy Pascal Chastagner Stéphane Ducassou Xavier Rialland Denis Hémon Jacqueline Clavel | 2012 | Cancer Causes & Control2012，，8： | 2 |
| 7 | Experimental study of pulse-jet cleaning of bag filters supported by rigid rings显示文摘 | Xavier Simon Sandrine Chazelet Dominique Thomas Denis Bémer Roland Régnier | 2006 | Powder Technology2006，，2： | 2 |
| 8 | Chemical Coal Cleaning Using Selective Oxidation显示文摘 | Stephen R P Edwin J H Xavier A D | 1994 | Fuel1994，73，2： | 1 |
| 9 | The dimen-sionality of the Maslach Burnout Inventory across small business owners and educators 显示文摘 | BOLES J S DEAN D H XAVIER J M R | 2000 | Journal of Vocational Behavior2000，，： | 1 |
| 10 | Technological Diffusion,Con-vergence ,and Growth 显示文摘 | Barro R J Sala-i-Martin Xavier | 1997 | Journal of Economic Growth1997，2，1： | 1 |
| 11 | Mineral chemistry of ore and hydrothermal alteration an the sossego oirn ox- ide-copper-gold deposit, Carajas Mineral Province, Brazil 显示文摘 | Monteiro L V S Xavier R P Hitzman M W | 2008 | Ore Geology Reviews2008，34，： | 1 |
| 12 | Dynamic Behavior of the Doubly Fed Induction Generator During Three-Phase Voltage Dips显示文摘 | JESUS L PABLO S XAVIER R etc | 2007 | IEEE Transactions on Energy Conversion2007，22，3： | 1 |
| 13 | Identification of a novel Ras -regulated proapoptotic pathway显示文摘 | Khokhlatchev A Rabizadeh S Xavier R | 2002 | Curr Biol Curr Biol2002，12，4： | 1 |
| 14 | Microstructure,mechanical Properties and wearresistance of high speedsteel rolls for hot rolling mills 显示文摘 | Carvalho M A De Xavier R R Filho C S P | 2002 | I& SM2002，29，1： | 1 |
| 15 | Public Finance in Models of Economic Growth 显示文摘 | Barro R J Xavier Sala-I-Martin | 1992 | Review of Economic Studies1992，，59： | 1 |
| 16 | In vitro antibiotic susceptibility of field isolates of Mycoplasma synoviae in Argentina显示文摘 | Cerda R O Giacoboni G I Xavier J A | 2002 | Avian Diseases2002，46，1： | 1 |
| 17 | Paraffin/porous-graphite-matrix composite as a high and constant power thermal storage material 显示文摘 | Py Xavier Olives R e gis Mauran Sylvain | 2001 | International Journal of Heat and Mass Transfer2001，，44： | 1 |
| 18 | Affinity for inor- ganic carbon of Gracilaria tenuistipitata cultured at low and high irradiance 显示文摘 | Mercado J M Carmona R Xavier Niell F | 2000 | Planta2000，210，： | 1 |
| 19 | Dural fistulas of the anterior cranial fossal 显示文摘 | Xavier J Cruz R Stocker A | 2001 | Acta Med Port2001，14，5： | 1 |
| 20 | Value of frozen section examination for the management of nonpalpable incidental testicular tumors显示文摘 | Xavier L Jean-Marc R Sebastien | 2003 | Euro Urol2003，44，4： | 1 |
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