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| 1 | Daily Visibility and Hospital Admission in Shanghai, China显示文摘Objective The study is to investigate the associations between visibility, major air pollutants and daily counts of hospital admission in Shanghai, China. Methods Daily data on hospital admission, visibility, and air pollution during 2005‐2008 were obtained from the Shanghai Insurance Bureau (SHIB), Shanghai Meteorological Bureau, and Shanghai Environmental Monitoring Center, respectively. The generalized additive model (GAM) with penalized splines was used to examine the associations between daily visibility and hospital admission. Results Among various pollutants, PM 2.5 showed strongest correlation with visibility. Decreased visibility was significantly associated with increased risk of hospital admission in Shanghai. An inter‐quartile range decrease in the 2‐day (L01) moving average of visibility corresponded to 3.66% (95%CI: 1.02%, 6.31%), 4.06% (95%CI: 0.84%, 7.27%), and 4.32% (95%CI: 1.67%, 6.97%) increase of total, cardiovascular, and respiratory hospitalizations, respectively. Conclusion Our analyses provide the first piece of evidence in China, demonstrating that decreased visibility has an effect on hospital admission, and this finding strengthens the rationale for further limiting air pollution levels in Shanghai. | GE WenZhen CHEN RenJie SONG WeiMin KAN HaiDong | 2011 | Biomedical and Environmental Sciences2011，24，2： | 9 |
| 2 | Pt- based anode catalysts for direct ethanol fuel cells 显示文摘 | Zhou Weijiang Song Shuqing Li Wenzhen | 2004 | Solid State Ionics2004，175，： | 1 |
| 3 | Beyond the Green Revolution: Improving crop productivity and sustainability by modulating plant growth-metabolic coordination显示文摘Rice is one of the most important staple food for over half the world's population.New evidence from the Food and Agriculture Organization shows that the number of hungry people in the world is growing,reaching more than 690 million in 2020.It is an urgent task to increase crop production to feed the people suffering from chronic hunger in the world.The Green Revolution of the 1960s boosted cereal yields through widespread adoption of semi-dwarf varieties and extensive use of inorganic fertilizers(Khush,2001).Today,the most productive Green Revolution varieties(GRVs)of rice and wheat in the world retain semi-dwarf phenotypes,which have several advantages over tall traditional varieties:(1)they have a lower center of gravity of the plant body,which decreases the risk of lodging and allows farmers to apply excessive fertilizers to obtain high yield;(2)they have an increased harvest index,which enables plants to allocate more energy and resources to seed production。 | Qian Liu Kun Wu Yunzhe Wu Wenzhen Song Shuoxun Wang Xiangdong Fu | 2022 | Molecular Plant2022，15，4： | 1 |
| 4 | Pyramiding of the dep1-1 and NAL1NJ6 alleles achieves sustainable improvements in nitrogen-use efficiency and grain yield in japonica rice breeding显示文摘Rice is one of the most important cereal crops in the world, and a substantial increase in grain yield is necessary for food security. However, high yields of semidwarf modern rice varieties are heavily dependent on the application of mineral nitrogenous fertilizer (Tilman et al., 2002;Sun et al., 2014). Nitrogen (N)-insensitive sponses associated with reduced N-use efficiency (NUE) is a major characteristic of the green revolution varieties (GRVs), in which the growth-inhibiting protein SLENDER RICE1 (SLR1) accumulates (Li et al., 2018). Unfortunately, increasing the level of N fertilizer use to reach the full yield potential of GRVs is subject to diminishing returns, quite apart from its deleterious effect on the environments (Rahn et al., 2009;Liu et al., 2015). Therefore, there is an urgent need to develop new rice GRVs that increase NUE while maintaining their high yields. Recently, several genes (e.g., DEP1, OsNRTl.lB, OsNRT2.3b, ARE1 and GRF4) responsible for improved NUE have been identified in rice (Sun et al.. 2014;Hu et al., 2015;Fan et al., 2016;Wang et al., 2018;Li et al., 2018). More importantly, boosting the activity of the transcription factor GRF4 overcomes the ability of SLR1 to prevent the GRF4-GIF1 interaction, which in turn promotes the coordinated expression of the genes involved in N assimilation and carbon fixation and consequently enhances the NUE of rice GRVs, thereby improving our ability to grow crops sustainably (Li et al., 2018). However, current understanding of the genetic basis for improving NUE remains at the level of identification of a number of quantitative trait loci (QTLs), without any understanding of the nature of the gene products. | Xiaopeng Xu Kun Wu Ruineng Xu Jianping Yu Jing Wang Ying Zhao Yun Wang Wenzhen Song Shuoxun Wang Zhi Gao Yongjia Zhong Xinxin Li Hong Liao Xiangdong Fu | 2019 | Journal of Genetics and Genomics2019，46，6： | 1 |
| 5 | Modulating the C-terminus of DEP1 synergistically enhances grain quality and yield in rice显示文摘Grain shape is a key breeding target that influences both grain yield and appearance quality in rice. Breeding for long-slender grains is an effective strategy to improve grain quality (Jain et al., 2004;Wang et al., 2012, 2015a). In the past two decades, several quantitative trait loci (QTLs) responsible for grain size and shape have been identified, including GS3 (Fan et al., 2006), GS5 (Li et al., 2011). | Haixiang Huang Yafeng Ye Wenzhen Song Qi Li Ruixi Han Chenchen Wu Shuoxun Wang Jianping Yu Xueying Liu Xiangdong Fu Qian Liu Kun Wu | 2022 | Journal of Genetics and Genomics2022，49，5： | 1 |
| 6 | Design and performance of an air inflatable suit in enhancing personal thermal management显示文摘Maintaining human thermal comfort in cold indoor environments is crucial but usually involves excessive energy consumption and massive greenhouse gas emissions. Thermoregulating the human body by using advanced clothing is emerging as a promising solution to effectively and energy-efficiently achieve personal thermal management. An air inflatable suit(AirST)using a series of air chambers as the thermal insert was developed for the purpose of adjusting clothing thermal insulation and hence improving personal thermal comfort. The thermal insulation regulating performance of AirST was investigated through thermal manikin tests and wear trials. Compared with the AirST without air inflation, AirST after inflation with air had a desired effect, which could not only increase local clothing thermal insulation by a range from 4.5% to 24.8% but also alleviate cold strain and provide significantly higher local skin temperatures, mean skin temperature and mean body temperature. After inflation, AirST successfully improved the whole-, upper-and lower-body thermal sensations in a cool environment. The acceptable heating setpoint temperature by the air conditioner could be decreased while using AirST with inflation, which saved approximately 30% of building energy consumption. As the AirST without air inflation can also be worn as regular windproof clothing, this versatility saved approximately 12 kg CO_(2)e emissions in the production process. | HE JiaZhen LU YeHu SU WenZhen WANG FangMing SONG WenFang WANG LaiLi WANG Min | 2023 | Science China(Technological Sciences)2023，66，9： | 0 |
| 7 | Simultaneous acquisition of CT angiography and whole brain CT perfusion images by using multiphase dynamic helical scan on 16 MDCT显示文摘We implemented a new protocol—multiphase dynamic helical scan to acquire CT angiography(CTA)and whole brain CT perfusion(CTP)images simulta-neously with single scan on 16 multidetector CT(MDCT).A total of 90 patients who were randomly assigned into 3 groups were included in our study.Each group underwent CT scan by using the new protocol,traditional CTA and CTP protocol,respectively.The image quality of CTA,the CTP parameter values and the X-ray doses were measured and compared between the new protocol and the traditional protocols.There was no statistically significant difference in the CTA image quality between the above methods(P=0.55).For CTP parameters,the new protocol tended to overestimate the blood volume(BV)and bloodflow(BF)value,and to underestimate the mean transit time(MTT)value compared with the traditional method.However,there was no statistically significant difference in BV,BF,and MTT value between the two methods except permeability surface(PS)(P>0.05).The volume CT dose index(CTDIvol)and dose length product(DLP)of our protocol were lower than the traditional one.The new protocol can obtain valuable diagnostic information in a shorter time without significant compromise in image quality.In addition,it reduces the radiation dose as well as contrast medium usage on the patient. | Weiwei CHEN Jianpin QI Wenzhen ZHU Wenhua HUANG Jinmei SONG | 2009 | Frontiers of Medicine2009，3，2： | 0 |
| 8 | Study design of deep learning based automatic detection of cerebrovascular diseases on medical imaging: a position paper from Chinese Association of Radiologists显示文摘In recent years,with the development of artificial intelligence,especially deep learning technology,researches on automatic detection of cerebrovascular diseases on medical images have made tremendous progress and these models are gradually entering into clinical practice.However,because of the complexity and flexibility of the deep learning algorithms,these researches have great variability on model building,validation process,performance description and results interpretation.The lack of a reliable,consistent,standardized design protocol has,to a certain extent,affected the progress of clinical translation and technology development of computer aided detection systems.After reviewing a large number of literatures and extensive discussion with domestic experts,this position paper put forward recommendations of standardized design on the key steps of deep learning-based automatic image detection models for cerebrovascular diseases.With further research and application expansion,this position paper would continue to be updated and gradually extended to evaluate the generalizability and clinical application efficacy of such tools. | Longjiang Zhang Zhao Shi Min Chen Yingmin Chen Jingliang Cheng Li Fan Nan Hong Wenxiao Jia Guihua Jiang Shenghong Ju Xiaogang Li Xiuli Li Changhong Liang Weihua Liao Shiyuan Liu Zaiming Lu Lin Ma Ke Ren Pengfei Rong Bin Song Gang Sun Rongpin Wang Zhibo Wen Haibo Xu Kai Xu Fuhua Yan Yizhou Yu Yunfei Zha Fandong Zhang Minwen Zheng Zhen Zhou Wenzhen Zhu Guangming Lu Zhengyu Jin on behalf of Chinese Association of Radiologists | 2022 | Intelligent Medicine2022，2，4： | 0 |
| 9 | Thermal perception method of virtual chemistry experiments显示文摘Background With the aim of addressing the difficulty in identifying temperatures in virtual chemistry experiments,we propose a temperature-sensing simulation method of virtual chemistry experiments.Methods We construct a virtual chemistry experiment temperature simulation platform,based on which a wearable temperature generation device is developed.The typical middle school virtual experiments of concentrated sulfuric acid dilution and ammonium nitrate dissolution are conducted to verify the actual effect of the device.Results The platform is capable to indicate near real-world experimental situations.The performance of the device not only meets the temperature sensing characteristics of human skin,but also matches the temperature change of virtual chemistry experiments in real-time.Conclusions It is demonstrated that this temperature-sensing simulation method can represent exothermic or endothermic chemistry experiments,which is beneficial for students to gain understanding of the principles of thermal energy transformation in chemical reactions,thus avoiding the danger that may be posed in the course of traditional teaching of chemistry experiments effectively.Although this method does not have a convenient enough operation for users,the immersion of virtual chemical experiments can be enhanced. | Hengwei XU Siru LI Wenpeng SONG Jiajun SUN Xinli WU Xiaoqi WANG Wenzhen YANG Zhigeng PAN Abdennour EI RHALIBI | 2020 | Virtual Reality & Intelligent Hardware2020，2，4： | 0 |
| 10 | Mitigating growth-stress tradeoffs via elevated TOR signaling in rice显示文摘Rice production accounts for approximately half of the freshwater resources utilized in agriculture,result-ing in greenhouse gas emissions such as methane(CH4)from flooded paddy fields.To address this chal-lenge,environmentally friendly and cost-effective water-saving techniques have become widely adopted in rice cultivation.However,the implementation of water-saving treatments(WsTs)in paddy-field rice has been associated with a substantial yield loss of up to 50%as well as a reduction in nitrogen use efficiency(NUE).In this study,we discovered that the target of rapamycin(TOR)signaling pathway is compromised in rice under WsT.Polysome profiling-coupled transcriptome sequencing(polysome-seq)analysis unveiled a substantial reduction in global translation in response to WST associated with the downregulation of TOR activity.Molecular,biochemical,and genetic analyses revealed new insights into the impact of the positive TOR-S6K-RPS6 and negative TOR-MAF1 modules on translation repression under WST.Intriguingly,ammonium exhibited a greater ability to alleviate growth constraints under WsT by enhancing TOR signaling,which simultaneously promoted uptake and utilization of ammonium and nitrogen allocation.We further demonstrated that TOR modulates the ammonium transporter AMT1;1 as well as the amino acid permease APP1 and dipeptide transporter NPF7.3 at the translational level through the 5'untranslated region.Collectively,these findings reveal that enhancing TOR signaling could mitigate rice yield penalty due to WST by regulating the processes involved in protein synthesis and NUE.Our study will contribute to the breeding of new rice varieties with increased water and fertilizer utilization efficiency. | Wei Li Jiaqi Liu Zeqi Li Ruiqiang Ye Wenzhen Chen Yuqing Huang Yue Yuan Yi Zhang Huayi Hu Peng Zheng Zhongming Fang Zeng Tao Shiyong Song Ronghui Pan Jian Zhang Jumim Tu Jen Sheen Hao Du | 2024 | Molecular Plant2024，17，2： | 0 |
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