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| 1 | DNA methylation changes detected by methylation-sensitive amplified polymorphism in two contrasting rice genotypes under salt stress显示文摘DNA methylation,one of the most important epigenetic phenomena,plays a vital role in tuning gene expression during plant development as well as in response to environmental stimuli.In the present study,a methylation-sensitive amplified polymorphism(MSAP) analysis was performed to profile DNA methylation changes in two contrasting rice genotypes under salt stress.Consistent with visibly different phenotypes in response to salt stress,epigenetic markers classified as stable inter-cultivar DNA methylation differences were determined between salt-tolerant FL478 and salt-sensitive IR29.In addition,most tissue-specific DNA methylation loci were conserved,while many of the growth stage-dependent DNA methylation loci were dynamic between the two genotypes.Strikingly,salt stress induced a decrease in DNA methylation specifically in roots at the seedling stage that was more profound in IR29 than in the FL478.This result may indicate that demethylation of genes is an active epigenetic response to salt stress in roots at the seedling stage,and helps to further elucidate the implications of DNA methylation in crop growth and development. | Wensheng Wang Xiuqin Zhao Yajiao Pan Linghua Zhu Binying Fu Zhikang Li | 2011 | Journal of Genetics and Genomics2011，38，9： | 25 |
| 2 | Silencing RhoA inhibits migration and invasion through Wnt/β-catenin pathway and growth through cell cycle regulation in human tongue cancer显示文摘地岬相当或相同的事物基因家庭成员 A (RhoA ) 作为肿瘤的一个批评管理者被识别了好攻击的行为。在 thisstudy,我们在位于有鳞的细胞 carcinomaof 舌头(TSCC ) 的生长,移植,和侵略下面的机制估计了 RhoA 的角色。TSCC 房间线 SCC-4 和 CAL27 击倒的稳定的 RhoA 用 Lentiviral transfection 被完成。房间移植,侵略,和房间增长上的 RhoA 弄空的 Theeffects 是坚定的。TSCC 房间线上的可能的位于决定 Galectin-3 (Gal-3 ) 的表示下面 mechanismof RhoA 弄空被也评估,在 vivo 的 -catenin, andmatrix metalloproteinase-9 (MMP-9 ) 。同时, TSCC 生长的内在的机制被 cyclin D1/2 的分析学习, p21 CIP1/WAF1 , 和 p27 Kip1 蛋白质层次。Immunohistochemical 评价被执行进一步证明 Gal-3 和 -catenin expression.We 的改变发现了那,在与在舌头的人的 TSCC 房间注射的老鼠, RhoA 层次与在正常纸巾的那些相比在主要肿瘤和 metastasizedlymph 节点是更高的。RhoA 的 Silencing 显著地减少了肿瘤生长, Gal-3 的 decreasedthe 层次, -catenin, MMP-9,和 cyclin D1/2,并且增加了 p21 CIP1/WAF1 和 p27 Kip1 。在 vitro, RhoA 击倒也导致了房间移植,侵略,和增长的抑制。我们的数据建议 RhoA 由通过分别地通过房间周期规定表明小径 andcell 增长的 Wnt/-catenin 调整房间移植和侵略在 TSCC 前进起 asignificant 作用。RhoA 可能是 TSCC 的一个新奇治疗学的目标。 | Guoxin Yan Ronghai Zou Zhenggang Chen Bing Fan Zhaoyan Wang Ying Wang Xiaonan Yin Dong Zhang Lei Tong Fang Yang Weina Jiang Wensheng Fu Jiwei Zheng Martin O. Bergo Martin Dalin Jiawei Zheng Shulan Chen Jianhua Zhou | 2014 | Acta Biochimica et Biophysica Sinica2014，46，8： | 7 |
| 3 | Comparative analysis of metabolite changes in two contrasting rice genotypes in response to low-nitrogen stress显示文摘Identification of metabolites responsible for tolerance to low nitrogen availability(low-N)will aid in the genetic improvement of rice yield under nitrogen deficiency.In this study,a backcross introgression line(G9)and its recurrent parent Shuhui 527(SH527),which show differential responses to low-N stress,were used to identify metabolites associated with lowN tolerance in rice.Differences in metabolite contents in the leaves of G9 and SH527 at three growth stages under low-N stress were assessed by gas chromatography–mass spectrometry.Many metabolites,including amino acids and derivatives,were highly enriched in G9 compared with SH527 under the control condition,suggesting that the two genotypes had basal metabolite differences.Low-N stress induced genotype-specific as well as growth stagedependent metabolite changes.Metabolites induced specifically in G9 that were involved in glycolysis and tricarboxylic acid metabolism were enriched at the tillering and grain filling stages,and metabolites involved in nitrogen and proline metabolism were enriched at the booting stage.Enrichment of pyroglutamate,glutamate,2-oxoglutarate,sorbose,glycerate-2-P,and phosphoenolpyruvic acid in G9 suggests that these metabolites could be involved in low-N stress tolerance.The results presented here provide valuable information for further elucidation of the molecular mechanisms of low-N tolerance in crops. | Xiuqin Zhao Wensheng Wang Ziyan Xie Yongming Gao Chunchao Wang Muhammed Mahbubur Rashid Mohammad Rafiqul Islam Binying Fu Zhikang Li | 2018 | The Crop Journal2018，6，5： | 2 |
| 4 | Analysis of Transmission Characteristics of Copper/Carbon Nanotube Composite Through-Silicon Via Interconnects显示文摘We investigated the transmission charac-teristics of Cu/CNT composite Through-silicon via (TSV) interconnects. The equivalent lumped-element circuit model was established, with the effective conductivity employed for impedance extraction. The impacts of CNT filling ratio, temperature, and other geometrical param-eters on the performance were examined.The sensitivity analysis of Cu/CNT composite TSVs was carried out. The electrical performance of Cu/CNT composite TSVs were optimized by utilizing low-permittivity dielectrics or even air-gap. | FU Kai ZHENG Jie ZHAO Wensheng HU Yue WANG Gaofeng | 2019 | Chinese Journal of Electronics2019，28，5： | 2 |
| 5 | Balancing selection and wild gene pool contribute to resistance in global rice germplasm against planthopper显示文摘Interactions and co-evolution between plants and herbivorous insects are critically important in agriculture.Brown planthopper(BPH)is the most severe insect of rice,and the biotypes adapt to feed on different rice genotypes.Here,we present genomics analyses on 1,520 global rice germplasms for resistance to three BPH biotypes.Genome-wide association studies identified 3,502 single nucleotide polymorphisms(SNPs)and 59 loci associated with BPH resistance in rice.We cloned a previously unidentified gene Bph37 that confers resistance to BPH.The associated loci showed high nucleotide diversity.Genome-wide scans for trans-species polymorphisms revealed ancient balancing selection at the loci.The secondarily evolved insect biotypes II and III exhibited significantly higher virulence and overcame more rice varieties than the primary biotype I.In response,more SNPs and loci evolved in rice for resistance to biotypes II and III.Notably,three exceptional large regions with high SNP density and resistance-associated loci on chromosomes 4 and 6 appear distinct between the resistant and susceptible rice varieties.Surprisingly,these regions in resistant rice might have been retained from wild species Oryza nivara.Our findings expand the understanding of long-term interactions between rice and BPH and provide resistance genes and germplasm resources for breeding durable BPH-resistant rice varieties. | Cong Zhou Qian Zhang Yu Chen Jin Huang Qin Guo Yi Li Wensheng Wang Yongfu Qiu Wei Guan Jing Zhang Jianping Guo Shaojie Shi Di Wu Xiaohong Zheng Lingyun Nie Jiaoyan Tan Chaomei Huang Yinhua Ma Fang Yang Xiqin Fu Bo Du Lili Zhu Rongzhi Chen Zhikang Li Longping Yuan Guangcun He | 2021 | Journal of Integrative Plant Biology2021，63，10： | 2 |
| 6 | Genome and Comparative Transcriptomics of African Wild Rice Oryza Iongistaminata Provide Insights into Molecular Mechanism of Rhizomatousness and Self-Incompatibility显示文摘Dear Editor, Oryza Iongistaminata is an African wild rice species with AA genome type possessing special traits that are highly valued for improving cultivated rice,such as strong resistance to biotic and abiotic stresses (Song et al.,1995) for improving resistance of cultivars,rhizomatousness for perennial breeding (Glover et al.,2010),and self-incompatibility (SI) for new ways to produce hybrid seeds (Ghesquiere,1986).Deciphering the genome of O.longistaminata will be the key to uncovering the mechanism of these hallmark traits and improving cultivated rice. | Yesheng Zhang Shilai Zhang Hui Liu Binying Fu Lijuan Li Min Xie Yue Song Xin Li Jing Cai Wenting Wan Ling Kui Hui Huang Jun Lyu Yang Dong Wensheng Wang Liyu Fluang Jing Zhang Qinzhong Yang Qinfi Shan Qiong Li Wangqi Huang Dayun Tao Muhua Wang Mingsheng Chen Yeisoo Yu Rod A. Wing Wen Wang Fengyi Hu | 2015 | Molecular Plant2015，8，11： | 1 |
| 7 | Deep transcriptome sequencing of rhizome and aerial-shoot in Sorghum propinquum显示文摘 | Ting Zhang Xiuqin Zhao Wensheng Wang Liyu Huang Xiaoyue Liu Ying Zong Linghua Zhu Daichang Yang Binying Fu Zhikang Li | 2014 | Plant Molecular Biology2014，，3： | 1 |
| 8 | The basic helix-loop-helix transcription factor gene,OsbHLH38,plays a key role in controlling rice salt tolerance显示文摘The plant hormone abscisic acid(ABA)is crucial for plant seed germination and abiotic stress tolerance.However,the association between ABA sensitivity and plant abiotic stress tolerance remains largely unknown.In this study,436 rice accessions were assessed for their sensitivity to ABA during seed germination.The considerable diversity in ABA sensitivity among rice germplasm accessions was primarily reflected by the differentiation between the Xian(indica)and Geng(japonica)subspecies and between the upland-Geng and lowland-Geng ecotypes.The upland-Geng accessions were most sensitive to ABA.Genome-wide association analyses identified four major quantitative trait loci containing21 candidate genes associated with ABA sensitivity of which a basic helix-loop-helix transcription factor gene,OsbHLH38,was the most important for ABA sensitivity.Comprehensive functional analyses using knockout and overexpression transgenic lines revealed that OsbHLH38 expression was responsive to multiple abiotic stresses.Overexpression of OsbHLH38 increased seedling salt tolerance,while knockout of OsbHLH38 increased sensitivity to salt stress.A salt-responsive transcription factor,OsDREB2A,interacted with OsbHLH38 and was directly regulated by OsbHLH38.Moreover,OsbHLH38 affected rice abiotic stress tolerance by mediating the expression of a large set of transporter genes of phytohormones,transcription factor genes,and many downstream genes with diverse functions,including photosynthesis,redox homeostasis,and abiotic stress responsiveness.These results demonstrated that OsbHLH38 is a key regulator in plant abiotic stress tolerance. | Fengping Du Yinxiao Wang Juan Wang Yingbo Li Yue Zhang Xiuqin Zhao Jianlong Xu Zhikang Li Tianyong Zhao Wensheng Wang Binying Fu | 2023 | Journal of Integrative Plant Biology2023，65，8： | 0 |
| 9 | Modern pollen assemblages and their relationships with vegetation and climate on the northern slopes of the Tianshan Mountains, Xinjiang, China显示文摘The reconstruction of paleovegetation and paleoclimate requires an understanding of the relationships between surface pollen assemblages and modern vegetation and climate.Here,we analyzed the characteristics of surface pollen assemblages across different vegetation zones in the Tianshan Mountains.Using surface pollen analysis and vegetation sample surveys at 75 sites on the northern slopes of the Tianshan Mountains,we determined the correlation between the percentage of dominant pollen types and the corresponding vegetation cover.Redundancy analysis was used to investigate the relationships between surface pollen assemblages and environmental factors.Our results show that the Tianshan Mountains contain several distinct ecological regions,which can be divided into five main vegetation zones from low to high altitudes:mountain desert zone(Hutubi County(HTB):500-1300 m;Qitai County(QT):1000-1600 m),mountain steppe zone(HTB:1400-1600 m;QT:1650-1800 m),mountain forest zone(HTB:1650-2525 m;QT:1850-2450 m),subalpine meadow zone(HTB:2550-2600 m;QT:2500-2600 m),and alpine mat vegetation zone(HTB:2625-2700 m;QT:2625-2750 m).The surface pollen assemblages of different vegetation zones can accurately reflect the characteristics of the mountainous vegetation patterns on the northern slopes of the Tianshan Mountains when excluding the widespread occurrence of Chenopodiaceae,Artemisia,and Picea pollen.Both average annual precipitation(P_(ann))and annual average temperature(T_(ann))affect the distribution of surface pollen assemblages.Moreover,P_(ann) is the primary environmental factor affecting surface pollen assemblages in this region.A significant correlation exists between the pollen percentage and vegetation cover of Picea,Chenopodiaceae,Artemisia,and Asteraceae.Moreover,Picea,Chenopodiaceae,and Artemisia pollen are over-represented compared with their corresponding vegetation cover.The Asteraceae pollen percentage roughly reflects the distribution of a species within the local vegetation.These results have important implications for enhancing our understanding of the relationship between surface pollen assemblages and modern vegetation and climate. | ZHANG Wensheng AN Chengbang LI Yuecong ZHANG Yong LU Chao LIU Luyu ZHANG Yanzhen ZHENG Liyuan LI Bing FU Yang DING Guoqiang | 2023 | Journal of Arid Land2023，15，3： | 0 |
| 10 | A theoretical study of the influence of dopants on the dehydrogenation properties of VH_2显示文摘Using the plane wave ultrasoft pseudopotential method based on the first-principles density functional theory(DFT),the influence on the electronic structure and dehydrogenation properties of VH2 doped with Zr,Cu and Zn has been studied.The results show that the negative heat of formation increases and the valence electron number at the Fermi level EF,N(EF) decreases in the Zr-doped model,indicating the higher stability of VH2 after Zr alloying.On the other hand,the negative heat of formation of VH2 decreases and the N(EF) increases in Cu-or Zn-doped systems,suggesting the lower stability of VH2 after Cu or Zn alloying.The calculated overlap populations and electron densities of the V-H bond demonstrate that the bonding is strengthened by Zr doping and weakened by Cu or Zn doping.The results predict that the maximum capacity to absorb and desorb hydrogen can be raised by the introduction of Zr and reduced by the introduction of Cu or Zn,while the dehydrogenation properties will be poorer in Zr-doped systems and enhanced in Cu-or Zn-doped systems.These predictions are consistent with the experimental results.Mulliken populations were also calculated and it was found that the Mulliken population of the V 3d orbitals decreased as a result of Zr doping,and increased after Cu or Zn doping. | LI Rong LUO XiaoLing LIANG GuoMing FU WenSheng | 2011 | Science China Chemistry2011，54，9： | 0 |
| 11 | In-situ synthesis of quantum dots in the nucleus of live cells显示文摘The cell nucleus is the main site for the storage and replication of genetic material,and the synthesis of substances in the nucleus is rhythmic,regular and strictly regulated by physiological processes.However,whether exogenous substances,such as nanoparticles,can be synthesized in situ in the nucleus of live cells has not been reported.Here,we have achieved in-situ synthesis of CdSx Se1−x quantum dots(QDs)in the nucleus by regulation of the glutathione(GSH)metabolic pathway.High enrichment of GSH in the nucleus can be accomplished by the addition of GSH with the help of the Bcl-2 protein.Then,high-valence Se is reduced to low-valence Se by glutathione-reductase-catalyzed GSH,and interacts with the Cd precursor formed through Cd and thiol-rich proteins,eventually generating QDs in the nucleus.Our work contributes to a new understanding of the syntheses of substances in the cell nucleus and wi l l pave the way for the development of advanced‘supercells’. | Yusi Hu Zhi-Gang Wang Haohao Fu Chuanzheng Zhou Wensheng Cai Xueguang Shao Shu-Lin Liu Dai-Wen Pang | 2024 | National Science Review2024，11，3： | 0 |
| 12 | Rice3K56 is a high-quality SNP array for genome-based genetic studies and breeding in rice(Oryza sativa L.)显示文摘Single nucleotide polymorphism(SNP)genotyping arrays provide an optimal high-throughput platform for genetic research and molecular breeding programs in both animals and plants.In this study,a highquality and custom-designed Rice3K56 SNP array was developed with the resequencing data of 3024 rice accessions worldwide,which was then tested extensively in 192 representative rice samples.Printed on the Gene Titan chips of Affymetrix Axiom each containing 56,606 SNP markers,the Rice3K56 array has a high genotyping reliability(99.6%),high and uniform genome coverage(an average of 6.7-kb between adjacent SNPs),abundant polymorphic information and easy automation,compared with previously developed rice SNP arrays.When applied in rice varietal differentiation,population diversity analysis,gene mapping of 13 complex traits by a genome-wide association study analysis(GWAS),and genome selection experiments in a recombinant inbred line and a multi-parent advanced generation inter-cross populations,these properties of the Rice3K56 array were well demonstrated for its power and great potential to be a highly efficient tool for rice genetic research and genomic breeding. | Chaopu Zhang Min Li Lunping Liang Jun Xiang Fan Zhang Chenyang Zhang Yizhen Li Jing Liang Tianqing Zheng Fanlin Zhang Hua Li Binying Fu Yingyao Shi Jianlong Xu Bingchuan Tian Zhikang Li Wensheng Wang | 2023 | The Crop Journal2023，11，3： | 0 |
| 13 | The ABA synthesis enzyme allele OsNCED2^(T)promotes dryland adaptation in upland rice显示文摘Upland rice shows dryland adaptation in the form of a deeper and denser root system and greater drought resistance than its counterpart,irrigated rice.Our previous study revealed a difference in the frequency of the OsNCED2 gene between upland and irrigated populations.A nonsynonymous mutation(C to T,from irrigated to upland rice)may have led to functional variation fixed by artificial selection,but the exact biological function in dryland adaptation is unclear.In this study,transgenic and association analysis indicated that the domesticated fixed mutation caused functional variation in OsNCED2,increasing ABA levels,root development,and drought tolerance in upland rice under dryland conditions.OsNCED2-overexpressing rice showed increased reactive oxygen species-scavenging abilities and transcription levels of many genes functioning in stress response and development that may regulate root development and drought tolerance.OsNCED2^(T)-NILs showed a denser root system and drought resistance,promoting the yield of rice under dryland conditions.OsNCED2^(T)may confer dryland adaptation in upland rice and may find use in breeding dryland-adapted,water-saving rice. | Liyu Huang Yachong Bao Shiwen Qin Min Ning Qinyan Li Qingmao Li Shilai Zhang Guangfu Huang Jing Zhang Wensheng Wang Binying Fu Fengyi Hu | 2024 | The Crop Journal2024，12，1： | 0 |
| 14 | The etching strategy of zinc anode to enable high performance zinc-ion batteries显示文摘Zinc-ion batteries(ZIBs)are considered to be one of the most promising candidates to replace lithium-ion batteries(LIBs)due to the high theoretical capacity,low cost and intrinsic safety.However,zinc dendrites,hydrogen evolution reaction,surface passivation and other side reactions will inevitably occur during the charging and discharging process of Zn anode,which will seriously affect the cycle stability of the battery and hinder its practical application.The etching strategy of Zn anode has attracted wide attention because of its simple operation and broad commercial prospects,and the etched Zn anode can effectively improve its electrochemical performance.However,there is no comprehensive review of the etching strategy of Zn anode.This review first summarizes the challenges faced by Zn anode,then puts forward the etching mechanisms and properties of acid,salt and other etchants.Finally,based on the above discussion,the challenges and opportunities of Zn anode etching strategy are proposed. | Xueqing Fu Gaopeng Li Xinlu Wang Jinxian Wang Wensheng Yu Xiangting Dong Dongtao Liu | 2024 | Journal of Energy Chemistry2024，88，1： | 0 |
| 15 | Differential microRNA expression between shoots and rhizomes in Oryza longistaminata using high-throughput RNA sequencing显示文摘Plant microRNAs(miRNAs)play important roles in biological processes such as development and stress responses.Although the diverse functions of miRNAs in model organisms have been well studied,their function in wild rice is poorly understood.In this study,high-throughput small RNA sequencing was performed to characterize tissue-specific transcriptomes in Oryza longistaminata.A total of 603 miRNAs,380 known rice miRNAs,72 conserved plant miRNAs,and151 predicted novel miRNAs were identified as being expressed in aerial shoots and rhizomes.Additionally,99 and 79 miRNAs were expressed exclusively or differentially,respectively,in the two tissues,and 144 potential targets were predicted for the differentially expressed miRNAs in the rhizomes.Functional annotation of these targets suggested that transcription factors,including squamosa promoter binding proteins and auxin response factors,function in rhizome growth and development.The expression levels of several miRNAs and target genes in the rhizomes were quantified by RT-PCR,and the results indicated the existence of complex regulatory mechanisms between the miRNAs and their targets.Eight target cleavage sites were verified by RNA ligase-mediated rapid 5′end amplification.These results provide valuable information on the composition,expression and function of miRNAs in O.longistaminata,and will aid in understanding the molecular mechanisms of rhizome development. | Ying Zong Liyu Huang Ting Zhang Qiao Qin Wensheng Wang Xiuqin Zhao Fengyi Hu Binying Fu Zhikang Li | 2014 | The Crop Journal2014，2，Z1： | 0 |
| 16 | Dominant early heading without yield drag in a sister-line BC breeding progeny DEH_229 is controlled by multiple genetic factors with maineffect loci显示文摘Dominant early heading(DEH)in rice(Oryza sativa L.)is of interest in both breeding and genetics.The genetic mechanisms underlying DEH have remained largely unclear.We have developed a near-isogenic DEH line without yield drag named DEH_229 by sister-line backcross(BC)breeding with MH63,a restorer,as the genetic background.We conducted a pilot genetic investigation under both short-day(SD)and long-day(LD)conditions.The DEH line harbored only 1.06%variation in the genome sequence relative to MH63.The variants were distributed throughout the genome.Using QTL mapping by sequencing(QTL-seq)on an F_(2) population derived from a cross of MH63×DEH_229,57 loci were detected under the SD condition.Joint mapping employing a genome-wide association study with accessions from the 3000 rice genome sequencing project(3K-RG),reduced the number of QTL by 43.9%.Using Rice Functional Genomics&Breeding(RFGB)database,the number of SNP cluster regions within the QTL regions reduced by 27.3%.Further comparison of the genome variation between DEH_229 and MH63 in addition to gene annotation information revealed a new DEH allele of DTH3 with multiple variable sites as a possible major factor underlying the early-heading phenotype of DEH_229.An InDel marker,ZMEH_1,was designed based on the variation between DEH_229 and MH63 within this region.It accounted for 86.0%of heading date variation under both SD and LD conditions in 109 randomly chosen progeny derived from extreme lines of the MH63×DEH_229 population.This study reveals the genetic complexity of DEH in the near-isogenic line and may provide useful material and marker information for plant molecular breeding. | Muhiuddin Faruquee Qiang Zhang Lubiao Zhang Linyun Xu Wensheng Wang Jiansan Chen Jianlong Xu Zhikang Li Binying Fu Tianqing Zheng | 2021 | The Crop Journal2021，9，2： | 0 |
| 17 | Effect of New Dayuan powder on methicillin-resistant Staphylococcus aureus biofilms in vitro显示文摘OBJECTIVE:To observe the effects of New Dayuan powder(NDYP)on Methicillin-resistant Staphylococcus aureus(MRSA)biofilms and the embedded bacteria in vitro.METHODS:2,3-Bis-(2-methoxy-4-nitro-5-sulfophenyl)-2 H-tetrazolium-5-carboxanilide(XTT)assays were used to study the effects of NDYP on developing MRSA biofilms:100μL of bacterial culture and100μL drug solution were added to wells of96-well plates.After 24 h of incubation,the plates were washed and XTT-phenazine methyl sulfate(PMS)was added to enable counting of the number of live bacteria in biofilms using a microplate reader.XTT assays were also used to explore the effects of NDYP on mature MRSA biofilms:100μL of bacterial culture were added to wells of 96-well plates.Bacteria were cultured in the plates for 24 h,and then drug solution was added.The plates were cultured for another 24 h,and then XTT-PMS was added to detect the number of live bacteria in the biofilms.Scanning electron microscopy(SEM)was used to observe the effects of NDYP on mature MRSA biofilms:washed and sterilized glass coverslips were added to 24-well plates.Bacterial culture was added.After 24 h of incubation,drug solution was added.After another 24 h of incubation,the samples were observed by SEM.RESULTS:XTT assays showed that the number of live bacteria in both developing and mature MRSA biofilms decreased significantly(P<0.01)after the administration of NDYP.SEM images showed that NDYP could destroy the structure of the bacteria and resulted in uneven thickness of MRSA biofilms.CONCLUSION:In vitro,NDYP has obvious inhibitory effects on the formation of MRSA biofilms and on mature biofilms. | Zhu Li Liu Chang Zuo Xue Fu Zheng Wang Yinghui Wang Yi Qi Wensheng | 2019 | Journal of Traditional Chinese Medicine2019，39，6： | 0 |
| 18 | Unveiling the Hidden Movements in the Shuttling of Rotaxanes显示文摘Movements in molecular machines are usually diverse and coupled,but some of them are often implicit and hard to be observed in experiments.In the present work,the two-or three-dimensional free-energy landscapes characterizing the coupled shutthng and other movements of a series of pH-triggered rotaxanes composed of a crown ether and an H-shaped axle with distinct number of phenyl rings(n=1-3)have been explored.The results show that although the calculated free-energy barriers against shutthng in the rotaxanes(n=2 and 3)change slightly,the move-ments coupled with the shutthng vary significantly with the axle length.At high pH,the shutthng in the rotaxane of n=2 is coupled with the isomerization of the wheel,while the shutthng in the one of n=3 is accompanied by both the isomerization and the rotation of the macrocycle.In addition,the crown ether imdenvent greater conlomiational change during shutthng at low pH compared to that at high pH.These results indicate that disentangling the coupled movements is important to reveal the underlying molecular mechanism of the shutthng. | GUO Yichang FU Haohao SHAO Xueguang CAI Wensheng | 2020 | Chemical Research in Chinese Universities2020，36，5： | 0 |
| 19 | Research Progress of Superhydrophobic Polymer Composite Coatings for os Magnesium Alloys显示文摘Magnesium(Mg)alloy is the lightest metal material found because of its excellent physical and mechanical properties,specific strength,biocompatibility and biomechanical compatibility,therefore,it has very promising development prospects in aerospace,automobile manufacturing,and biodegradable materials.However,due to the relatively chemical properties of magnesium alloys,poor corrosion resistance,fast degradation rate,and poor wear resistance,they have been greatly restricted in practical applications.Therefore,anti-corrosion measures of magnesium alloys are particularly important.The manufacture of hydrophobic surfaces is a very effective method of anti-corrosion.The surface of super-hydrophobic polymer composites(i.e.,thin coatings)is constructed on the surface of magnesium alloy materials to enhance their corrosion resistance and wear resistance,and the effect of its antiseptic measures is very impressive. | Yufang Luo Wensheng Fu Jingjin Tan Bohan Jiang | 2020 | Journal of Metallic Material Research2020，3，1： | 0 |
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