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| 1 | Structural Surface Crack Monitoring Method Based on Electrical Potential Technique and Modern Surface Technology显示文摘Crack monitoring plays a great role in modern structural health monitoring, however, most of the conventional crack inspections have disadvantages in terms of the accuracy, expense, reliability, durability and level of instrumentation required. Thus, development of a simple and reliable crack inspection technique that allows continuous monitoring has been desired. In this paper, electrical potential technique and modern surface technology are employed together to develop a new structural surface crack monitoring method. A special crack monitoring coating sensor based on electrical potential technique was deposited on the hot spot of the structure by modern surface technology. The sensor consists of three layers: the isolated layer, the sensing layer and the protective layer. The isolated layer is prepared by anodic oxidation technology, the sensing layer is made of ion plated copper, and the protective layer is made of silicone. The thickness of each layer is at micrometer magnitude. The electrical conductivity of the sensor is very stable, and the fatigue performance of the specimen with or without coating sensor is nearly unchanged. The crack monitoring experiment result shows that there are two sudden rises of the coating sensor electrical potential values, corresponding to different stages of the crack initiation and propagation. Since the width of the surface coating sensor is only 0.5 mm, this crack monitoring sensor can detect the propagation of cracks less than 0.5 mm long. The method proposed takes the simplicity of electrical potential technique and can monitor surface crack of nearly all kinds of structures precisely. The results of this paper may form the basis of a new crack monitoring system. | CUI Ronghong HE Yuting YU Zhiming LI Hongpeng SHU Wenjun DU Jinqiang | 2011 | Chinese Journal of Mechanical Engineering2011，24，4： | 7 |
| 2 | Changes in soil microbial community response to precipitation events in a semi-arid steppe of the Xilin River Basin, China显示文摘In the context of climate change, precipitation is predicted to become more intense at the global scale. Such change may alter soil microbial communities and the microbially mediated carbon and nitrogen dynamics. In this study, we experimentally repackaged precipitation patterns during the growing season(from June to September) of 2012 in a semi-arid temperate steppe of the Xilin River Basin in Inner Mongolia of China, based on the 60-year growing season precipitation data. Specifically, a total amount of 240 mm simulated precipitation was assigned to experimental plots by taking the following treatments:(1) P6(6 extreme precipitation events, near the 1^(st) percentile);(2) P10(10 extreme precipitation events, near the 5^(th) percentile);(3) P16(16 moderate precipitation events, near the 50^(th) percentile); and(4) P24(24 events, 60-year average precipitation, near the 50^(th) percentile). At the end of the growing season, we analyzed soil microbial community structure and biomass, bacterial abundance, fungal abundance and bacterial composition, by using phospholipid fatty acid(PLFA), real-time quantitative polymerase chain reaction(RT-qPCR) and 16S rRNA gene clone library methods. The extreme precipitation events did not change soil microbial community structure(represented by the ratio of PLFA concentration in fungi to PLFA concentration in bacteria, and the ratio of PLFA concentration in gram-positive bacterial biomass to PLFA concentration in gram-negative bacterial biomass). However, the extreme precipitation events significantly increased soil microbial activity(represented by soil microbial biomass nitrogen and soil bacterial 16S rRNA gene copy numbers). Soil fungal community showed no significant response to precipitation events. According to the redundancy analysis, both soil microbial biomass nitrogen and soil ammonium nitrogen(NH_4-N) were found to be significant in shaping soil microbial community. Acidobacteria, Actinobacteria and Proteobacteria were the dominant phyla in soil bacterial composition, and responded differently to the extreme precipitation events. Based on the results, we concluded that the extreme precipitation events altered the overall soil microbial activity, but did not impact how the processes would occur, since soil microbial community structure remained unchanged. | ZHANG Hui LIU Wenjun KANG Xiaoming CUI Xiaoyong WANG Yanfen ZHAO Haitao QIAN Xiaoqing HAO Yanbin | 2019 | Journal of Arid Land2019，11，1： | 5 |
| 3 | Correlation-enhanced electron-phonon coupling for accurate evaluation of the superconducting transition temperature in bulk FeSe显示文摘It has been widely recognized that,based on standard density functional theory calculations of the electron-phonon coupling,the superconducting transition temperature(T_(c))in bulk FeSe is exceptionally low(almost 0 K)within the Bardeen-Cooper-Schrieffer formalism.Yet the experimentally observed T_(c)is much higher(∼10 K),and the underlying physical origin remains to be fully explored,especially at the quantitative level.Here we present the first accurate determination of T_(c)in FeSe where the correlation-enhanced electron-phonon coupling is treated within first-principles dynamical mean-field theory.Our studies treat both the multiple electronic bands across the Fermi level and phononic bands,and reveal that all the optical phonon modes are effectively coupled with the conduction electrons,including the important contributions of a single breathing mode as established by previ-ous experiments.Accordingly,each of those phonon modes contributes pronouncedly to the electron pairing,and the resultant T_(c)is drastically enhanced to the experimentally observed range.The approach developed here should be broadly applicable to other superconducting systems where correlation-enhanced electron-phonon coupling plays an important role. | Wenjun Ding Yilin Wang Tong Wei Jiaqing Gao Ping Cui Zhenyu Zhang | 2022 | Science China(Physics,Mechanics & Astronomy)2022，65，6： | 5 |
| 4 | Post-marketing safety surveillance and reevaluation of Motherwort injection:A clinical study of 10094 cases显示文摘OBJECTIVE:To investigate the safety profiles of Motherwort injection(MI).METHODS:A multi-center,prospective and drugderived hospital intensive monitoring method was conducted to assess the safety of MI in real world applications.This study was based on a very large population after the injection was approved and marketed in China.All patients using the injection in participating hospitals were monitored to determine the incidence,pattern,severity and outcome of associated adverse events.RESULTS:The post-marketing surveillance was performed in 10 094 female patients from April to December,2015.The incidence of adverse drug reactions(ADRs) was 0.79‰(8/10 094).Among the 8 patients,the reported adverse events mainly included systemic abnormalities,such as fever,chills and eyelid edema;skin and appendages disorders,such as pruritus and rash;gastrointestinal disorders,such as nausea,abdominal distension and pain;heart rate and rhythm disorders,such as palpitation and increased heart rate.All of these ADRs were mild in severity.CONCLUSION:In this study the ADRs incidence rate of MI is very low,which supports that it is generally safe for use in obstetric and gynecological diseases.However,the total number of 8 ADRs recorded over a relatively short time span seems limited,and the low number of reports could not represent an absolute guarantee of safety. | Cao Shan Zhang Wenhao Zhao Ziwei Heng Mingli Bu Huaien Wang Hongwu Liu Xinghui Wang Zhong Cai Yan Ma Yuyan Cui Shihong Deng Jihong Ding Guifeng Ding Yajuan Dong Linhong Duan Zhentao Fan Ling Fan Yang Fu Fen He Jing Ji Shuying Jin Lin Li Hong Li Hongying Liao Tao Lu Wei Luo Xiucui Lü Zhihui Ma Fengchun Ma Dafeng Shi Tianyun Sun Juying Sun Xiaotong Teng Hong Wang Jinhua Wang Ruihua Wang Ying Wang Zhengling Xi Jie Xu Minjuan Xu Zhihong Yan Qian Yang Cuirong Yang Yimei Yin Jie Yu Jinhua Yuan Wenjun Zhang Guanli Zhang Meihua Zhao Renfeng Zhong Yonghong Zhou Jian | 2018 | Journal of Traditional Chinese Medicine2018，38，4： | 4 |
| 5 | Interferon as a Mucosal Adjuvant for an Influenza Vaccine in Pigs显示文摘Interferon,a natural protein that is produced by a variety of cells during viral infection,activates the transcription of multiple functional genes in cells,regulates synergy among various signaling pathways,and mediates many biological functions such as antiviral activity,immune regulation,and cell growth.However,clinical research on interferon in livestock is lacking.In this study,recombinant porcine interferon(PoIFNα)was used as an adjuvant,in combination with inactivated influenza virus,to vaccinate 6-week-old pigs via nasal infusion.The transcription of target genes was then monitored and the functions of PoIFNαwere determined with respect to the activation of mucosal immunity.We found that a combination of low-dose PoIFNαand in activated influenza virus could significantly up-regulate the expression of immunoregulatory cytokines such as IL-2,IL-1β,IFN-γ,IL-6,and IL-10 by real-time PCR,suggesting the induction of a strong mucosal innate immune response after administration.In addition,low-dose PoIFNαcan significant enhancing the transcription of genes encoding homing factors including CCR9 and CCR10(P<0.001),thereby resulting in the induction of higher levels of HA-specific antibodies(P<0.05),which can be determined by ELISA and IFA.Post-immunization challenges with H1N1 virus demonstrated that PoIFNot,combined with inactivated influenza virus,could alleviate clinical signs in pigs during the early stages of viral infection.These studies reveal low-dose PoIFNαas a potential mucosal adjuvant for influenza virus in pigs. | Lirong Liu Wenhui Fan He Zhang Shuang Zhang Liang Cui Meng Wang Xiaoyuan Bai Wenxian Yang Lei Sun Limin Yang Wenjun Liu Jing Li | 2019 | Virologica Sinica2019，34，3： | 3 |
| 6 | CypA Regulates AIP4-Mediated M1 Ubiquitination of Influenza A Virus显示文摘Cyclophilin A (CypA) is a peptidyl-prolyl cis/trans isomerase that interacts with the matrix protein (M1) of influenza A virus (IAV) and restricts virus replication by regulating the ubiquitin–proteasome-mediated degradation of M1. However,the mechanism by which CypA regulates M1 ubiquitination remains unknown. In this study, we reported that E3 ubiquitin ligase AIP4 promoted K48-linked ubiquitination of M1 at K102 and K104, and accelerated ubiquitin–proteasome-mediated degradation of M1. The recombinant IAV with mutant M1 (K102 R/K104 R) could not be rescued, suggesting that the ubiquitination of M1 at K102/K104 was essential for IAV replication. Furthermore, CypA inhibited AIP4-mediated M1 ubiquitination by impairing the interaction between AIP4 and M1. More importantly, both the mutations of M1 (K102 R/K104 R) and CypA inhibited the nuclear export of M1, indicating that CypA regulates the cellular localization of M1 via inhibition of AIP4-mediated M1 ubiquitination at K102 and K104, which results in the reduced replication of IAV.Collectively, our findings reveal a novel ubiquitination-based mechanism by which CypA regulates the replication of IAV. | Madina Mahesutihan Weinan Zheng Liang Cui Yun Li Pengtao Jiao Wenxian Yang Wei Liu Jing Li Wenhui Fan Limin Yang Wenjun Liu Lei Sun | 2018 | Virologica Sinica2018，33，5： | 3 |
| 7 | Construction of the Chinese Veteran Clinical Research (CVCR) Platform for the assessment of non-communicable diseases显示文摘 | Tan Jiping Li Nan Gao Jing Guo Yuhe Hu Wei Yang Jinsheng Yu Baocheng Yu Jianmin Du Wei Zhang Wenjun Cui Lianqi Wang Qingsong Xia Xiangnan Li Jianjun Zhou Peiyi Zhang Baohe Liu Zhiying Zhang Shaogang Sun Lanying Liu Nan Deng Ruixiang Dai Wenguang Yi Fang Chen Wenjun Zhang Yongqing Xue Shenwu Cui Bo Zhao Yiming Wang Luning | 2014 | Chinese Medical Journal2014，，3： | 3 |
| 8 | Coil-levitated hybrid generator for mechanical energy harvesting and wireless temperature and vibration monitoring显示文摘The development of wireless monitoring is currently restricted by the short lifetime of batteries,requiring frequent replacement.Utilization of abundant mechanical energy from the surrounding environment has attracted increasing attention in real-time monitoring.Herein,a coil-levitated hybrid generator was developed for the efficient harvesting of mechanical energy from mechanical motion.The novel coil-levitated structure adapted to the metal and magnetic environment.The output currents were systematically analyzed at different operation modes based on the unique combination of triboelectrification,electromagnetic induction,and piezoelectric effect.Under the excitation of vibration frequency and amplitude of 8 Hz and 5 mm respectively,the as-constructed triboelectric nanogenerator delivered a peak power density of 11.40 W/m3 at 10 MΩ.Meanwhile,the middle electromagnetic part and bottom piezoelectric generator provided peak power densities of 6.97 and 79.93 W/m2 at 10000Ω,respectively.More importantly,the battery charging experiment was verified,in which a 30 mA h Li-ion battery can be charged from 2.57 to 3.27 V in about 90 min.In sum,a self-powered temperature and vibration monitoring system was successfully developed based on hybrid generator,promising for realizing wireless monitoring of mechanical equipment without any external power supply. | XUE XiaoBin ZHANG ZengXing WU Bin HE ShanShan WANG Qiang ZHANG WenJun BI RuiYu CUI Juan ZHENG YongQiu XUE ChenYang | 2021 | Science China(Technological Sciences)2021，64，6： | 2 |
| 9 | Maternal genetic history of ancient Tibetans over the past 4000 years显示文摘The settlement of the Tibetan Plateau epitomizes human adaptation to a high-altitude environment that poses great challenges to human activity.Here,we reconstruct a 4000-year maternal genetic history of Tibetans using 128 ancient mitochondrial genome data from 37 sites in Tibet.The phylogeny of haplotypes M9a1a,M9a1b,D4g2,G2a’c,and D4i show that ancient Tibetans share the most recent common ancestor with ancient Middle and Upper Yellow River populations around the Early and Middle Holocene.In addition,the connections between Tibetans and Northeastern Asians vary over the past 4000 years,with a stronger matrilineal connection between the two during 4000 BPe3000 BP,and a weakened connection after 3000 BP,that are coincident with climate change,followed by a reinforced connection after the Tubo period(1400 BPe1100 BP).Besides,an over 4000-year matrilineal continuity is observed in some of the maternal lineages.We also find the maternal genetic structure of ancient Tibetans is correlated to the geography and interactions between ancient Tibetans and ancient Nepal and Pakistan populations.Overall,the maternal genetic history of Tibetans can be characterized as a long-term matrilineal continuity with frequent internal and external population interactions that are dynamically shaped by geography,climate changes,as well as historical events. | Ganyu Zhang Can Cui Shargan Wangdue Hongliang Lu Honghai Chen Lin Xi Wei He Haibing Yuan Tinley Tsring Zujun Chen Feng Yang Tashi Tsering Shuai Li Norbu Tashi Tsho Yang Yan Tong Xiaohong Wu Linhui Li Yuanhong He Peng Cao Qingyan Dai Feng Liu Xiaotian Feng Tianyi Wang Ruowei Yang Wanjing Ping Ming Zhang Xing Gao Yichen Liu Wenjun Wang Qiaomei Fu | 2023 | Journal of Genetics and Genomics2023，50，10： | 1 |
| 10 | Notes in accordions-organized MXene equipped with CeO_(2) for synergistically adsorbing and catalyzing polysulfides for high-performance lithium-sulfur batteries显示文摘Limited by the shuttle effect, the application of lithium-sulfur batteries is not impressive. As an organ layered two-dimensional(2D) material, MXene has a great electrical conductivity and high specific surface area. Meanwhile, the introduction of metal oxides can restrain the shuttle effect. Hence, this paper prepared CeO_(2)/MXene as a cathode material of Li-S batteries. Ce and Ti can chemically adsorb S, and the interlayer structure of MXene can limit S while the interlayer space can alleviate volume expansion.The discharge capacity at 0.5 C is as high as 1051.1 m Ah g^(-1), and 921.9 m Ah g^(-1) after 200 cycles. The average coulombic efficiency is 97.75%. The organized MXene with CeO_(2) like notes in accordions are new efficient materials for lithium-sulfur batteries. | Xiaochuan Chen Libo Li Yuhang Shan Da Zhou Wenjun Cui Yangmingyue Zhao | 2022 | Journal of Energy Chemistry2022，31，7： | 1 |
| 11 | The effect of SARS-CoV-2 infection on human embryo early development:a multicenter prospective cohort study显示文摘Dear Editor,Severe acute respiratory syndrome coronavirus 2(SARSCo V-2)infection has swept the globe for 3 years(Zhou et al.,2020).With the nationwide relaxation of controls on the coronavirus disease 2019(COVID-19)epidemic since December 2022 in China,fertility and in vitro fertilization(IVF)centers are receiving increasing numbers of infected patients. | Xiaolei Chen Huangcong Shi Cheng Li Wanxia Zhong Linlin Cui Wenjun Zhang Ling Geng Kuona Hu Mei Fang Daimin Wei Junhao Yan Yun Sun Keliang Wu Han Zhao Zi-Jiang Chen | 2023 | Science China(Life Sciences)2023，66，7： | 1 |
| 12 | Enhanced thermoelectric performance and atomic-resolution interfacial structures in BiSbTe thermo-electro-magnetic nanocomposites incorporating magnetocaloric LaFeSi nanoparticles显示文摘Incorporating magnetic nanoparticles in thermoelectric(TE)materials introduce magnetic interfaces with additional electron and phonon scattering mechanism for high TE performance.However,the influence of heterogeneous interfaces between magnetic nanoparticles and TE matrix on electronic and thermal transport remains elusive in the thermo-electric-magnetic nanocomposites.Here,using p-type TE material Bi_(0.3)Sb_(1.7)Te_(3)(BST)as matrix and magnetocaloric(MC)material La(Fe_(0.92)Co_(0.08))_(11.9)Si_(1.1)(LFS)nanoparticles as a second phase,TE/MC nanocomposites xLFS/BST(x=0.1%,0.2%,0.3% and 0.4%)were synthesized using spark plasma sintering method.The atomic-resolution interfacial structures demonstrate that Te vacancies originating from LFS-BST interfacial reaction decreases the hole concentration of the LFS/BST nanocomposites and enhances the Seebeck coefficient.The LFS/BST nanocomposites exhibit lower thermal conductivity due to enhanced phonon scattering by interfaces and defects.All the nanocomposites have higher ZT than BST matrix,with 0.2% LFS/BST nanocomposite achieving highest ZT=1.11 at 380 K.At working current 1.4 A,the device fabricated using 0.2% LFS/BST nanocomposite achieves maximal cooling temperature 4.9 K,which is 58% higher than the matrix.Moreover,the MC properties are retained in all the nanocomposites,which make them a promising candidate to achieve high TE performance and dual TE/MC properties for future applications. | Lin Xing Wenjun Cui Xiahan Sang Fengxia Hu Ping Wei Wanting Zhu Xiaolei Nie Qingjie Zhang Wenyu Zhao | 2021 | Journal of Materiomics2021，7，5： | 1 |
| 13 | Ultrafine Fe/Fe3C decorated on Fe-N_(x)-C as bifunctional oxygen electrocatalysts for efficient Zn-air batteries显示文摘Efficient bifunctional oxygen electrocatalysts for ORR and OER are fundamental to the development of high performance metal-air batteries.Herein,a facile cost-efficient two-step pyrolysis strategy for the fabrication of a bifunctional oxygen electrocatalyst has been proposed.The efficient non-preciousmetal-based electrocatalyst,Fe/Fe_(3)C@Fe-N_(x)-C consists of highly curved onion-like carbon shells that encapsulate Fe/Fe_(3)C nanoparticles,distributed on an extensively porous graphitic carbon aerogel.The obtained Fe/Fe_(3)C@Fe-N_(x)-C aerogel exhibited superb electrochemical activity,excellent durability,and high methanol tolerance.The experimental results indicated that the assembly of onion-like carbon shells with encapsulated Fe/Fe_(3)C yielded highly curved carbon surfaces with abundant Fe-Nxactive sites,a porous structure,and enhanced electrocatalytic activity towards ORR and OER,hence displaying promising potential for application as an air cathode in rechargeable Zn-air batteries.The constructed Zn-air battery possessed an exceptional peak power density of~147 mW cm^(-2),outstanding cycling stability(200 cycles,1 h per cycle),and a small voltage gap of 0.87 V.This study offers valuable insights regarding the construction of low-cost and highly active bifunctional oxygen electrocatalysts for efficient air batteries. | Lingbo Zong Xin Chen Siliang Liu Kaicai Fan Shuming Dou Jie Xu Xiaoxian Zhao Wenjun Zhang Yaowen Zhang Weicui Wu Fenghong Lu Lixiu Cui Xiaofei Jia Qi Zhang Yu Yang Jian Zhao Xia Li Yida Deng Yanan Chen Lei Wang | 2021 | Journal of Energy Chemistry2021，30，5： | 1 |
| 14 | Excessive branched-chain amino acid accumulation restricts mesenchymal stem cell-based therapy efficacy in myocardial infarction显示文摘Mesenchymal stem cells(MSCs)delivered into the post-ischemic heart milieu have a low survival and retention rate,thus restricting the cardioreparative efficacy of MSC-based therapy.Chronic ischemia results in metabolic reprogramming in the heart,but little is known about how these metabolic changes influence implanted MSCs.Here,we found that excessive branched-chain amino acid(BCAA)accumulation,a metabolic signature seen in the post-ischemic heart,was disadvantageous to the retention and cardioprotection of intramyocardially injected MSCs.Discovery-driven experiments revealed that BCAA at pathological levels sensitized MSCs to stress-induced cell death and premature senescence via accelerating the loss of histone 3 lysine 9 trimethylation(H3K9me3).A novel mTORC1/DUX4/KDM4E axis was identified as the cause of BCAA-induced H3K9me3 loss and adverse phenotype acquisition.Enhancing BCAA catabolic capability in MSCs via genetic/pharmacological approaches greatly improved their adaptation to the high BCAA milieu and strengthened their cardioprotective efficacy.We conclude that aberrant BCAA accumulation is detrimental to implanted MSCs via a previously unknown metabolite-signaling-epigenetic mechanism,emphasizing that the metabolic changes of the post-ischemic heart crucially influence the fate of implanted MSCs and their therapeutic benefits. | Fuyang Zhang Guangyu Hu Xiyao Chen Ling Zhang Lanyan Guo Congye Li Hang Zhao Zhe Cui Xiong Guo Fangfang Sun Dandan Song Wenjun Yan Yunlong Xia Shan Wang Miaomiao Fan Ling Tao | 2022 | Signal Transduction and Targeted Therapy2022，7，7： | 1 |
| 15 | Elodexanthones A—J, Isoprenylated Xanthone Derivatives with Diverse Skeletons and Bioactivities from Hypericum elodeoides显示文摘Elodexanthones A—J (1—10), two pairs of rearranged isoprenylated xanthone enantiomers with an unprecedent 6/6/5/6 tetracyclic core (1—2) along with seven new isoprenylated xanthones (3—9) and a pair of phenylpropanoid xanthones (10), were purified and enantio-separated from the whole plant of Hypericum elodeoides. Their structures including absolute configurations were characterized by the comprehensive analysis of NMR, HRESIMS, NMR calculations, and ECD calculations. Through Bayer-Villiger oxidation, Claisen condensation and electrophilic addition, the rearranged skeletons of elodexanthones A—B (1—2) were generated from isoprenylated xanthone precursors. The bioactivities evaluation exhibited that compounds 3, 5, 8—10 showed anti-inflammatory activity with the IC_(50) values in the range of 9.53—34.39 μmol/L, and compounds 3—7, and 9 showed notable α-glucosidase inhibitory activity (IC_(50): 6.02—257.11 μmol/L). | Yanbing Mu Yaqi Li Qiji Li Wenjun Xu Yunpeng Sun Siyuan Wang Letian Cui Lingyi Kong Jun Luo | 2022 | Chinese Journal of Chemistry2022，40，24： | 1 |
| 16 | High-precision potassium isotope analysis using the Nu Sapphire collision cell(CC)-MC-ICP-MS显示文摘This study presents high-precision analyses of stable potassium(K)isotope ratio using the recently-developed,collision-cell multi-collector inductively coupled plasma mass spectrometry(CC-MC-ICP-MS,Nu Sapphire).The accuracy of our analyses is confirmed by measuring well-characterized geostandards(including rocks and seawater).Our results are consistent with literature values and a precision of 0.04‰(2SD)has been achieved based on multiple measurements of BCR-2 geostandard over a six-month period.We also evaluate factors that may lead to artificial isotope fractionations,including the mismatches in K concentration and acid molarity between samples and bracketing standards,as well as potential matrices.As the K adsorption capacity of AGW50-X8(200-400 mesh)is reduced with an increasing amount of matrix elements,less than 150µg K was loaded during the column chemistry.To evaluate the potential use of K isotopes as an archive of paleo seawater composition,δ^(41)K values of an international seawater standard(IAPSO),a Mn-nodule(NOD-P-1),and two iron formation standards(FeR-2 and FeR-4)are reported.The δ^(41)K value of IAPSO is consistent with other seawater samples reported previously,further substantiating a homogeneous K isotopic distribution in modern global oceans.The K isotopes in Mn-nodule(NOD-P-1:−0.121±0.013‰)and iron formation samples(FeR-2:−0.538±0.009‰;FeR-4:−0.401±0.008‰)seem to be an effective tracer of their formation genesis and compositional changes of ancient seawater.Our results suggest that high-precision measurements of stable K isotopes can be routinely obtained and open up a large variety of geological applications,such as continental weathering,hydrothermal circulation and alteration of oceanic crust. | Wenjun LI Mengmeng CUI Qiqi PAN Jing WANG Bingyu GAO Shanke LIU Meng YUAN Benxun SU Ye ZHAO Fang-Zhen TENG Guilin HAN | 2022 | Science China Earth Sciences2022，65，8： | 1 |
| 17 | Boosting in-plane anisotropy by periodic phase engineering in two-dimensional VO_(2) single crystals显示文摘In-plane anisotropy(IPA)due to asymmetry in lattice structures provides an additional parameter for the precise tuning of characteristic polarization-dependent properties in two-dimensional(2D)materials,but the narrow range within which such method can modulate properties hinders significant development of related devices.Herein we present a novel periodic phase engineering strategy that can remarkably enhance the intrinsic IPA obtainable from minor variations in asymmetric structures.By introducing alternant monoclinic and rutile phases in 2D VO_(2)single crystals through the regulation of interfacial thermal strain,the IPA in electrical conductivity can be reversibly modulated in a range spanning two orders of magnitude,reaching an unprecedented IPA of 113.Such an intriguing local phase engineering in 2D materials can be well depicted and predicted by a theoretical model consisting of phase transformation,thermal expansion,and friction force at the interface,creating a frame-work applicable to other 2D materials.Ultimately,the considerable adjustability and reversibility of the presented strategy provide opportunities for future polarization-dependent photoelectric and optoelectronic devices. | Meng Ran Chao Zhao Xiang Xu Xiao Kong Younghee Lee Wenjun Cui Zhi-Yi Hu Alexander Roxas Zhengtang Luo Huiqiao Li Feng Ding Lin Gan Tianyou Zhai | 2022 | Fundamental Research2022，2，3： | 0 |
| 18 | Roles of pH in the NH_(4)^(+)-induced corrosion of AZ31 magnesium alloy in chloride environment显示文摘Corrosion behavior of AZ31 magnesium alloy in NH_(4)^(+)-bearing chloride solution with controlled pH was investigated by weight loss experiment, hydrogen collection, and electrochemical test combined with surface morphology and topography observation. The results show that NH_(4)^(+) and pH of the solution can affect the corrosion of AZ31 magnesium alloy. The existence of NH4+affects the formation and dissolution of corrosion products, which makes the protective effect of the corrosion product layer weaker. The change of pH value not only affects the corrosion mechanism of AZ31, but also alters the concentration of NH_(4)^(+) ions in the solution, which further influences the corrosion product layer of AZ31, and finally makes the corrosion of AZ31 change significantly. | Feng Ge Jiaxuan Yin Yue Liu Wenjun Leng Xin Wang Zhongyu Cui | 2022 | Journal of Magnesium and Alloys2022，10，11： | 0 |
| 19 | Nucleoprotein phosphorylation site(Y385)mutation confers temperature sensitivity to influenza A virus due to impaired nucleoprotein oligomerization at a lower temperature显示文摘Mutations in viral proteins can lead to the cold adaption of influenza A virus and the cold-adapted virus is an important vaccination instrument.Here,we identify a novel strain of influenza A virus with cold sensitivity conferred by a mutation at a phosphorylation site within the nucleoprotein(NP).The highly conserved tyrosine 385 residue(Y385)of NP was identified as a phosphorylation site by mass spectrometry.The constructive NP phosphorylation mimicked by Y385 E mutation was fatal for virus replication,while the continuous Y385 dephosphorylation mimicked by Y385 F mutation had little impact on virus replication in vitro.Notably,the Y385 F virus showed much lower replicative capacity in turbinates of mice compared with the wild type virus.Moreover,the replication of Y385 F virus was significantly reduced in both A549 and MDCK cells grown at 33℃,when compared to that at 37℃.These results indicated that the Y385 F mutation led to cold sensitivity of virus.We further found that the cold sensitivity of Y385 F virus could be attributed to diminished NP oligomerization rather than any changes in intracellular localization.Taken together,these findings suggest that the phosphorylation of NP may be a critical factor that regulates the temperature sensitivity of influenza A virus. | Weinan Zheng Liang Cui Minghui Li Yun Li Wenhui Fan Limin Yang Jing Li Lei Sun Wenjun Liu | 2021 | Science China(Life Sciences)2021，64，4： | 0 |
| 20 | Water resource conservation promotes synergy between economy and environment in China’s northern drylands显示文摘Water resource availability is the major limiting factor for sustainable development in drylands.Climate change intensifies the conflicting water demands between people and the environment and highlights the importance of effective water resource management for achieving a balance between economic development and environmental protection.In 2008,Inner Mongolia,typical dryland in northern China,proposed strict regulations on water exploitation and utilization aimed at achieving sustainable development.Our study is the first to investigate the effectiveness and performance of these long-standing water conservation regulations.Our analyses found that the regulations drove industrial transformation,evidenced by the decreasing proportion of environmentally harmful industries such as coal and steel,and the increasing proportion of tertiary industries(especially tourism).Following industrial transformation,economic development decoupled from industrial water consumption and subsequently led to reduced negative environmental impacts.Based on these results,adaptive strategies were developed for 12 cities by revealing and integrating their development pathways and relative status in achieving sustainable development.Integration and cooperation between cities were proposed,e.g.,a water trade agreement between eastern Inner Mongolia(an economically underdeveloped region with relatively abundant water resources)and central Inner Mongolia(an economically developed region with high water stress).Such an agreement may enable the holistic achievement of sustainable development across regions.By integrating the findings of our research,our study presents a reproducible framework for water-management-based sustainable development strategies in drylands. | Yali Liu Jianqing Du Boyang Ding Yuexian Liu Wenjun Liu Anquan Xia Ran Huo Qinwei Ran Yanbin Hao Xiaoyong Cui Yanfen Wang | 2022 | Frontiers of Environmental Science & Engineering2022，16，3： | 0 |
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