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| 1 | Efficacy of Chinese herbal medicine for lumbar disc herniation: a systematic review of randomized controlled trials显示文摘OBJECTIVE: This is a review of the effects of Chinese herbal medicine(CHM) used alone to treat lumbar disc herniation(LDH). METHORDS: A literature search of the following electronic databases from their inception to February 2013 was conducted: Chinese Biomedical databases, Chinese National Knowledge Infrastructure, Wanfang Database, China Science and Technology Journal Database, Cochrane Library, Web of Science, MEDLINE, and EMBASE. Randomized controlled trials where CHM had been used to treat LDH were selected. Data extraction, quality assessment, and data analysis were carried out by two independent reviewers. RESULTS: Of the 2415 studies identified, eight with complete data on 1146 patients were selected. The methodological quality was poor in all trials. Five studies reported that CHM was better than Western Medicine [OR=2.81, 95% CI(1.27, 6.18); OR=3.34, 95% CI(1.92, 5.79); OR=2.22, 95% CI(1.08, 4.57); OR= 6.67, 95% CI(1.34, 33.28); and OR=1.94, 95% CI(1.23, 3.06)]. Two studies reported that the clinical outcome was better in CHM groups than in physiotherapy and placebo groups, [OR=3.02, 95% CI(1.08, 8.46); and OR=2.67, 95% CI(1.26, 5.64), respectively], whereas one study reported no difference between CHM and physiotherapy groups. One study reported that CHM resulted in higher Japanese Orthopedic Association scores [MD=7.78, 95% CI(6.67, 8.89)] than in a control group and another that participants treated with CHM had lower Visual Analogue Scale scores [MD=﹣0.72, 95% CI( ﹣0.86, ﹣0.58)] than those in a control group. Three studies reported that the adverse effects of CHM and Western Medicine did not differ significantly [OR=0.10, 95% CI(0.01, 1.85); OR=0.19, 95% CI(0.01, 4.07); and OR=0.07, 95% CI(0.00, 1.32)]. CONCLUSION: CHM may be more effective than other interventions for LDH; however, methodological weaknesses in the studies assessed in this review prevent a definitive conclusion. More high-quality large-scale studies are required to clarify this matter. | Yi Luo Jian Huang Lin Xu Weikang Zhao Jie Hao Zhenming Hu | 2013 | Journal of Traditional Chinese Medicine2013，33，6： | 15 |
| 2 | Control measures during the COVID-19 outbreak reduced the transmission of hand,foot,and mouth disease显示文摘Control measures during the coronavirus disease 2019(COVID-19)outbreak may have limited the spread of infectious diseases.This study aimed to analyze the impact of COVID-19 on the spread of hand,foot,and mouth disease(HFMD)in China.A mathematical model was established to fit the reported data of HFMD in six selected cities in China's Mainland from 2015 to 2020.The absolute difference(AD)and relative difference(RD)between the reported incidence in 2020,and simulated maximum,minimum,or median incidence of HFMD in 2015-2019 were calculated.The incidence and R effof HFMD have decreased in six selected cities since the outbreak of COVID-19,and in the second half of 2020,the incidence and R effof HFMD have rebounded.The results show that the total attack rate(TAR)in 2020 was lower than the maximum,minimum,and median TAR fitted in previous years in six selected cities(except Changsha City).For the maximum,median,minimum fitted TAR,the range of RD(%)is 42·20-99·20%,36·35-98·41%48·35-96·23%(except Changsha City)respectively.The preventive and control measures of COVID-19 have significantly contributed to the containment of HFMD transmission. | Yan Niu Li Luo Jia Rui Shiting Yang Bin Deng Zeyu Zhao Shengnan Lin Jingwen Xu Yuanzhao Zhu Yao Wang Meng Yang Xingchun Liu Tianlong Yang Weikang Liu Peihua Li Zhuoyang Li Chan Liu Jiefeng Huang Tianmu Chen | 2021 | Journal of Safety Science and Resilience2021，2，2： | 3 |
| 3 | Ghrelin prevents doxorubicin-induced cardiotoxicity through TNF-alpha/NF-κB pathways and mitochondrial protective mechanisms显示文摘 | Zhiwei Xu Shiqing Lin Weikang Wu Hongmei Tan Zhi Wang Chao Cheng Lihe Lu Xuanhong Zhang | 2008 | Toxicology2008，，2： | 1 |
| 4 | Ghrelin prevents doxorubicin-induced cardiotoxicity through TNF-alpha/NF-kappaB pathways and mitochondrial protective mechanisms显示文摘 | XU Zhiwei LIN Shiqing WU Weikang | 2008 | Toxicology2008，247，23： | 1 |
| 5 | Wavelet transform based new methods for voltage flicker signal and harmonic detection显示文摘 | Zhou Wenhui Lin Lili Ye Xiuqing Gu Weikang | 2003 | Power Electronics and Drive Systems2003，1，11： | 1 |
| 6 | Vascular Endothelial Growth Factor‑Recruiting Nanofiber Bandages Promote Multifunctional Skin Regeneration via Improved Angiogenesis and Immunomodulation显示文摘Tissue injury leads to gradients of chemoattractants,which drive multiple processes for tissue repair,including the inflam-matory response as well as endogenous cell recruitment.However,a limited time window for the gradients of chemoattract-ants as well as their poor stability at the injury site may not translate into healthy tissue repair.Consequently,intelligent multifunctional scaffolds with the capability to stabilize injury-induced cytokines and chemokines hold great promise for tissue repair.Vascular endothelial growth factor(VEGF)plays a significant role in wound healing by promoting angiogen-esis.The overarching objective of this research was to develop intelligent multifunctional scaffolds with the capability to endogenously recruit VEGF and promote wound healing via angiogenic and immunomodulatory dual functions.Prominin-1-derived peptide(PR1P)was encapsulated into electrospun poly(L-lactide-coglycolide)/gelatin(P/G)-based bandages.The sustained release of PR1P recruited VEGF in situ,thereby stabilizing the protein concentration peak in vivo and affording a reparative microenvironment with an adequate angiogenic ability at the wound site.Meanwhile,PR1P-recruited VEGF-induced macrophage reprogramming towards M2-like phenotypes further conferred immunomodulatory functions to the bandages.These dual functions of proangiogenesis and immunomodulation formed a cascade amplification,which regulated matrix metalloproteinases(MMP-9)as well as inflammatory factors(nuclear factor(NF)-κb,tumor necrosis factor(TNF)-α)in the wound microenvironment via the VEGF/macrophages/microenvironment axis.Consequently,the bandages realized multifunctional regeneration in splinted excisional wounds in rats,with or without diabetes,affording a higher skin append-age neogenesis,sensory function,and collagen remodeling.Conclusively,our approach encompassing in situ recruitment of VEGF at the injury site with the capability to promote immunomodulation-mediated tissue repair affords a promising avenue for scarless wound regeneration,which may also have implications for other tissue engineering disciplines. | Yi Chen Zhengchao Yuan Weiyan Sun Muhammad Shafiq Jun Zhu Jiafei Chen Hai Tang Ling Hu Weikang Lin Yanxi Zeng Long Wang Lei Zhang Yunlang She Hui Zheng Guofang Zhao Dong Xie Xiumei Mo Chang Chen | 2023 | Advanced Fiber Materials2023，5，1： | 1 |
| 7 | Adding power of artificial intelligence to situational awareness of large interconnections dominated by inverter‐based resources显示文摘Large‐scale power systems exhibit more complex dynamics due to the increasing inte-gration of inverter‐based resources(IBRs).Therefore,there is an urgent need to enhance the situational awareness capability for better monitoring and control of power grids dominated by IBRs.As a pioneering Wide‐Area Measurement System,FNET/GridEye has developed and implemented various advanced applications based on the collected synchrophasor measurements to enhance the situational awareness capability of large‐scale power grids.This study provides an overview of the latest progress of FNET/GridEye.The sensors,communication,and data servers are upgraded to handle ultra‐high density synchrophasor and point‐on‐wave data to monitor system dynamics with more details.More importantly,several artificial intelligence(AI)‐based advanced appli-cations are introduced,including AI‐based inertia estimation,AI‐based disturbance size and location estimation,AI‐based system stability assessment,and AI‐based data authentication. | Lin Zhu Yinfeng Zhao Yi Cui Shutang You Wenpeng Yu Shengyuan Liu He Yin Chang Chen Yuru Wu Wei Qiu Mirka Mandich Hongyu Li Adedasola Ademola Chengwen Zhang Chujie Zeng Xinlan Jia Weikang Wang Haoyu Yuan Huaiguang Jiang Jin Tan Yilu Liu | 2021 | High Voltage2021，6，6： | 0 |
| 8 | Electroweak Axion in Light of GRB221009A显示文摘Very high energy(VHE)photons may have a higher survival rate than that expected in standard-model physics,as suggested by the recently reported gamma ray burst GRB221009A.While a photon-axion like particle(ALP)oscillation can boost the survival rate of the VHE photons,current works have not been based on concrete particle models,leaving the identity of the corresponding ALP unclear.Here,we show that the required ALP scenario is consistent with the electroweak axion with an anomaly free Z_(10)Froggatt–Nielsen symmetry. | Weikang Lin Tsutomu T.Yanagida | 2023 | Chinese Physics Letters2023，40，6： | 0 |
| 9 | Correction to:Vascular Endothelial Growth Factor‑Recruiting Nanofiber Bandages Promote Multifunctional Skin Regeneration via Improved Angiogenesis and Immunomodulation显示文摘Correction to:Advanced Fiber Materials http://gffzzd3cc09b8251d45dfswu0ofvkfop966x9b.ffgz.tsg.suse.edu.cn/10.1007/s42765-022-00226-8 In this article the author name Muhammad Shafiq was incorrectly written as Shafiq Muhammad.The original article has been corrected. | Yi Chen Zhengchao Yuan Weiyan Sun Muhammad Shafiq Jun Zhu Jiafei Chen Hai Tang Ling Hu Weikang Lin Yanxi Zeng Long Wang Lei Zhang Yunlang She Hui Zheng Guofang Zhao Dong Xie Xiumei Mo Chang Chen | 2023 | Advanced Fiber Materials2023，5，2： | 0 |
| 10 | Research on cooling-temperature control strategy of fuel-cell engine test bench显示文摘As one of the important ways to utilize hydrogen energy,fuel cells are receiving more and more attention and research from countries and institutions.To meet the practical needs of testing the performance of high-power fuel-cell systems and simulate the actual application environment as much as possible,a fuel-cell system test bench is usually used to test the system performance,in which the cooling-temperature control of the test bench has a great impact on the results of the performance of the fuel-cell system.This paper studies the cooling-temperature control strategy of a 150-kW-class fuel-cell engine test platform,proposes a new test-bench cooling-system structure with a thermostat and heat exchanger as the main heat-dissipation components,and compares and analyzes the impact of coordinated thermostat and heat-exchanger control on the fuel-cell system test performance.The test results show that the control strategy of the coordinated operation of a thermostat and heat exchanger can maintain the steady-state error to within±0.3℃and maintain the temperature variation to within±1.5℃during the loading-condition test,so as to avoid the limitation of system output performance due to excessive cooling-temperature fluctuation and ensure that the fuel-cell engine performance-test process is carried out smoothly and efficiently. | Chang Du Tiancai Ma Weikang Lin Kaihang Song Yonghao Liang | 2023 | Clean Energy2023，7，1： | 0 |
| 11 | A review on the sealing structure and materials of fuel-cell stacks显示文摘Proton-exchange-membrane fuel cells(PEMFCs)have the characteristics of zero emissions,a low operating temperature and high power density,and have great potential in improving energy-utilization efficiency.However,fuel cells are still quite expensive as a result of the cost of key components,including the membranes,catalysts and bipolar plates of PEMFCs.As a result of the cost and importance of these items,most researchers have focused on improving the lifetime and performance of fuel-cell stacks in recent years.In contrast,seals,sealants and adhesives play a more mundane role in the overall performance of a fuel cell,but failure of these materials can lead to reduced system efficiency,system failure and even safety issues.Little attention has been paid to the performance and durability of these products but as other fuel-cell components improve,these seals are becoming an even more critical link in the long-term performance of fuel cells.This article highlights the importance and background of fuel-cell seals.The latest research progress on the mechanical properties and structural optimization of different sealing materials is reviewed. | Jinghui Zhao Huijin Guo Yuchen Xing Shaobo Ping Weikang Lin Yanbo Yang Zixi Wang Tiancai Ma | 2023 | Clean Energy2023，7，1： | 0 |
| 12 | The anomalous shift of the weak boson mass and the quintessence electroweak axion显示文摘One of the simplest ways to account for the observed W-boson mass shift is to introduce the SU(2)L triplet Higgs boson with zero hypercharge,whose vacuum expectation value is about 3 GeV.If the triplet is heavy enough at O(1) TeV,it essentially contributes only to T parameter without any conflict with the observation.The presence of a complex triplet Higgs boson raises the SU(2)_(L) gauge coupling constant toα_(2)(M_(PL))≃1/44 at the Planck scale.Thanks to this larger gauge coupling constant,we show that the electroweak axion vacuum energy explains the observed cosmological constant provided that the axion field is located near the hill top of the potential at present. | Weikang Lin Tsutomu T Yanagida Norimi Yokozaki | 2023 | Communications in Theoretical Physics2023，75，3： | 0 |
| 13 | Multi-scale analysis of schizophrenia risk genes, brain structure, and clinical symptoms reveals integrative dues for subtyping schizophrenia patients显示文摘Analysis Unking directly genomics, neuroimaging phenotypes and clinical measurements is crucial for understanding psychiatric disorders, but remains rare.Here, we describe a multi-scale analysis using genome-wide SNPs, gene expression, grey matter volume (GMV), and the positive and negative syndrome scale scores (PANSS) to explore the etiology of schizophrenia. With 72 drug-naive schizophrenic first episode patients (FEPs) and 73 matched heathy controls, we identified 108 genes, from schizophrenia risk genes, that correlated significantly with GMV, which are highly co-expressed in the brain during development. Among these 108 candidates, 19 distinct genes were found associated with 16 brain regions referred to as hot clusters (HCs), primarily in the frontal cortex, sensory-motor regions and temporal and parietal regions.The patients were subtyped into three groups with distinguishable PANSS scores by the GMV of the identified HCs. Furthermore, we found that HCs with common GMV among patient groups are related to genes that mostly mapped to pathways relevant to neural signaling, which are associated with the risk for schizophrenia.Our results provide an integrated view of how genetic variants may affect brain structures that lead to distinct disease phenotypes.The method of multi-scale analysis that was described in this research, may help to advance the understanding of the etiology of schizophrenia. | Liang Ma Edmund T.Rolls Xiuqin Liu Yuting Liu Zeyu Jiao Yue Wang Weikang Gong Zhiming Ma Fuzhou Gong Lin Wan | 2019 | Journal of Molecular Cell Biology2019，11，8： | 0 |
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