|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Pandemic of the aging society—sporadic cerebral small vessel disease显示文摘Age-related sporadic cerebral small vessel disease(CSVD)has gained increasing attention over the past decades because of its increasing prevalence associated with an aging population.The widespread application of and advances in brain magnetic resonance imaging in recent decades have significantly increased researchers’understanding in the in vivo evolution of CSVD,its impact upon the brain,its risk factors,and the mechanisms that explain the various clinical manifestation associated with sporadic CSVD.In this review,we aimed to provide an update on the pathophysiology,risk factors,biomarkers,and the determinants and spectrum of the clinical manifestation of sporadic CSVD. | Alexander Yuk Lun Lau Bonaventure Yiu Ming Ip Ho Ko Bonnie Yin Ka Lam Lin Shi Karen Ka Yan Ma Lisa Wing Chi Au Yannie Oi Yan Soo Thomas Wai Hong Leung Adrian Wong Vincent Chung Tong Mok | 2021 | Chinese Medical Journal2021，，2： | 3 |
| 2 | Accuracy of Risk Scores for Patients With Chronic Hepatitis B Receiving Entecavir Treatment显示文摘 | Grace Lai–Hung Wong Henry Lik–Yuen Chan Hoi–Yun Chan Pete Chi–Hang Tse Yee–Kit Tse Christy Wing–Hin Mak Stanley King–Yeung Lee Zoe Man–Yi Ip Andrew Ting–Ho Lam Henry Wing–Hang Iu Joyce May–Sum Leung Vincent Wai–Sun Wong | 2013 | Gastroenterology2013，，5： | 2 |
| 3 | Entecavir treatment reduces hepatic events and deaths in chronic hepatitis B patients With liver cirrhosis显示文摘 | Grace Lai‐Hung Wong Henry Lik‐Yuen Chan Christy Wing‐Hin Mak Stanley King‐Yeung Lee Zoe Man‐Yi Ip Andrew Ting‐Ho Lam Henry Wing‐Hang Iu Joyce May‐Sum Leung Jennifer Wing‐Yan Lai Angeline Oi‐Shan Lo Hoi‐Yun Chan Vincent Wai‐Sun Wong | 2013 | Hepatology2013，，5： | 1 |
| 4 | A Hierarchical Multi-view Modeling for Networked Joint Manufacturing System显示文摘 | Kai Leung Yung Wai Hung Ip | 2004 | Computers in Industry2004，53，： | 1 |
| 5 | Multi-scale variability and trends of precipitation in North China显示文摘 | Wai Cheung Ip Zhang Liping Wong Heung | 2011 | Water Resources2011，38，1： | 1 |
| 6 | Serum levels of IL-33 and soluble ST2 and their association with disease activity in systemic lupus erythematosus显示文摘 | Mo Yin Mok Fang Ping Huang Wai Ki Ip | 2010 | Rheumatology2010，49，3： | 1 |
| 7 | Expression, secretion and functional characterization of three laccases in E. coli显示文摘Endocrine Disrupting Chemicals(EDCs)are a group of molecules that can influence hormonal balance,causing disturbance of the reproductive system and other health problems.Despite the efforts to eliminate EDC in the environment,all current approaches are inefficient and expensive.In previous research,studies revealed that laccase-producing microorganisms may be a potential candidate for EDC degradation,as laccases have been found to be able to degrade many kinds of EDCs effectively and steadily.Here,we created two recombinant laccases,each fused with secretion peptide,Novel Signal Peptide 4(NSP4),and expressed them in Escherichia coli(E.coli,BL21),together with one laccase without secretion peptide.We first optimized the culture condition of expressing these laccases.Then,we test the activity of the recombinant laccases of decolorizing of a synthetic dye,indigo carmine.Finally,we confirmed the secreted can degrade one of the EDCs,β-estradiol,showing the potential of using the laccase secretion system to degrade toxic compounds. | Yating Mo Hou Ip Lao Sau Wa Au Ieng Chon Li Jeremy Hu Hoi Man Yuen Wai Man Cheong Owen Lok In Lo Leo Chi U.Seak | 2022 | Synthetic and Systems Biotechnology2022，7，1： | 1 |
| 8 | The interferon gamma gene polymorphism +874A/T is associated with severe acute respiratory syndrome显示文摘 | Chong Wai Po Eddie Ip W K Gloria Hoi Wan Tso | 2006 | BMC Infect Dis2006，6，： | 1 |
| 9 | Over one hundred years of trace metal flures in the sediments of the Pearl River Estuary, South China显示文摘 | Ip C C M Li X D Zhang G Farmer J G Wai O W H Li Y S | 2004 | Environ Pollut2004，132，1： | 1 |
| 10 | Over one hundred years of trace metal fluxes in the sediments of the Pearl River Estuary, South China 显示文摘 | Ip C C M Li X D Zhang G Farmer J G Wai O W H Li Y S | 2004 | Environ Pollut2004，132，1： | 1 |
| 11 | Hepatocellular carcinoma: Current surgical management显示文摘 | Tae-Jin Song Edmund Wai Kit Ip Yuman Fong | 2004 | Gastroenterology2004，，5： | 1 |
| 12 | Transplantation of mesenchymal stem cells to the brain by topical application in an experimental traumatic brain injury model显示文摘 | Ping Kuen Lam Anthony Wing Ip Lo Kevin Ka Wan Wang Henry Chi Ho Lau Kevin Kai Chung Leung Kathy Tung Ching Li Paul Bo San Lai Wai Sang Poon | 2012 | Journal of Clinical Neuroscience2012，，： | 1 |
| 13 | Prophylactic and therapeutic treatments with AT 1 and AT 2 receptor antagonists and their effects on changes in the severity of pancreatitis显示文摘 | Siu Wai Tsang Siu Po Ip Po Sing Leung | 2003 | International Journal of Biochemistry and Cell Biology2003，，2： | 1 |
| 14 | Soft Computing Based Procurement Planning of Time-variable Demand in Manufacturing Systems显示文摘获得与改变需求的分离时间计划是在计划的企业资源(ERP ) 的一个重要问题。它能用在这篇论文建议的非分析的数学编程模型被描述。为了解决模型,我们建议基因算法到一个模糊决定嵌入的使用。算法采用一种顺序策略选择简化原来的真实优化问题进二进制的。然后,一个模糊决定 quantification 方法被用来确定从计划专家的经验。因此,决定规则能容易在基因操作的计算被嵌入。这条途径被使用在一个实际机床工作购买计划问题,在令人满意的结果被完成了的地方。关键词购买计划 - 计划的企业资源(ERP )- 软计算 - 基因 algorith - 模糊决定 - 库存控制这个工作被香港多种工艺的大学支持(没有。G.45.37.T363 ) ,并且中华人民共和国的国家自然科学基础(号码 70431003, 60521003 ) 。Kai Leung Yung 收到了他的 B.Sc。度从英国南部海岸的休大学,英国在 1975,从 Sci 的帝国学院的 M.Sc 学位。与技术,伦敦大学,英国在 1976,并且来自普利茅斯大学的博士学位,英国,在 1985。他为推进的 BOC 工作了为精确工程焊接公司有限公司,英国的曾经准备好了的组,和 Cranfield 单位,在英国。他当前是伙伴负责人和系的教授工业并且系统工程,香港多种工艺的大学。他的研究兴趣包括精确运动控制,计算机的系统方面综合生产和管理,并且逻辑计划和优化。Wai 挂了收到的 Ip 他在来自 Cranfield 大学,英国,和来自 Brunel 大学的 MBA 学位的工业工程的 M.Sc 学位,他在从 Loughborough 大学生产工程被授于博士度的英国,英国,在 1993。他当前是在部门的一个副教授工业并且系统工程,香港多种工艺的大学。他的研究兴趣包括基于 AI 的优化,决策,信息系统和决定支持系统。王定伟收到了他的 B.Sc。来自东北大学的度,中国在 1982,来自科技的 Huazhong 大学的 M.Sc 学位,中国在 1984,并且来自东北大学的博士学位,中国,在 1993。他是工作了一与北卡罗来纳州立大学医生以后,美国。他当前是设计的系统的研究所的一个教授,东北大学,中国。他的研究兴趣包括 ERP/MRP-II/JIT,当模特儿并且优化,计划并且安排的生产,模糊优化,和软计算。 | Kai Leung Yung Wai Hung Ip Ding-Wei Wang | 2007 | International Journal of Automation and computing2007，4，1： | 1 |
| 15 | Parametric Body Model Development显示文摘 | Peng Sixiang Chan Chee-Kooi Ameersing Luximon Ip Wai Hung | 2012 | Computer Technology and Application2012，3，3： | 0 |
| 16 | Genome sequencing reveals the role of rare genomic variants in Chinese patients with symptomatic intracranial atherosclerotic disease显示文摘Objectives The predisposition of intracranial atherosclerotic disease(ICAD)to East Asians over Caucasians infers a genetic basis which,however,remains largely unknown.Higher prevalence of vascular risk factors(VRFs)in Chinese over Caucasian patients who had a stroke,and shared risk factors of ICAD with other stroke subtypes indicate genes related to VRFs and/or other stroke subtypes may also contribute to ICAD.Methods Unrelated symptomatic patients with ICAD were recruited for genome sequencing(GS,60-fold).Rare and potentially deleterious single-nucleotide variants(SNVs)and small insertions/deletions(InDels)were detected in genome-wide and correlated to genes related to VRFs and/or other stroke subtypes.Rare aneuploidies,copy number variants(CNVs)and chromosomal structural rearrangements were also investigated.Lastly,candidate genes were used for pathway and gene ontology enrichment analysis.Results Among 92 patients(mean age at stroke onset 61.0±9.3 years),GS identified likely ICAD-associated rare genomic variants in 54.3%(50/92)of patients.Forty-eight patients(52.2%,48/92)had 59 rare SNVs/InDels reported or predicted to be deleterious in genes related to VRFs and/or other stroke subtypes.None of the 59 rare variants were identified in local subjects without ICAD(n=126).31 SNVs/InDels were related to conventional VRFs,and 28 were discovered in genes related to other stroke subtypes.Our study also showed that rare CNVs(n=7)and structural rearrangement(a balanced translocation)were potentially related to ICAD in 8.7%(8/92)of patients.Lastly,candidate genes were significantly enriched in pathways related to lipoprotein metabolism and cellular lipid catabolic process.Conclusions Our GS study suggests a role of rare genomic variants with various variant types contributing to the development of ICAD in Chinese patients. | Mengmeng Shi Xinyi Leng Ying Li Zihan Chen Ye Cao Tiffany Chung Bonaventure YM Ip Vincent HL Ip Yannie OY Soo Florence SY Fan Sze Ho Ma Karen Ma Anne Y Y Chan Lisa WC Au Howan Leung Alexander Y Lau Vincent CT Mok Kwong Wai Choy Zirui Dong Thomas W Leung | 2022 | Stroke & Vascular Neurology2022，7，3： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员