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| 1 | Effects of Yishengukang decoction on expression of bone-specific alkaline phosphatase,carboxyterminal propeptide of typeⅠprocollagen,and carboxyterminal cross-linked telepeptide of typeⅠcollagen in malignant tumor patients with bone metastasis显示文摘OBJECTIVE: To investigate the effect of Yishengukang decoction on the expression of the metabolic bone markers, bone-specific alkaline phosphatase(BAP), carboxyterminal propeptide of type Ⅰ procollagen(PICP), and carboxyterminal cross-linked telepeptide of type Ⅰ collagen(ICTP), in cancer patients with bone metastasis.METHODS: Patients(n = 180) were divided into three groups:(a) bone metastasis patients treated with Yishengukang and pamidronate disodium injection(treatment group, n = 60);(b) bone metastasis patients treated with pamidronate disodium injection alone(control group, n = 60);(c) cancer patients without metastatic bone lesion(non-bone metastasis group, n = 60). Serum levels of the metabolic markers BAP, PICP, and ICTP were detected by enzyme-linked immunosorbent assay pre- and post-therapy.RESULTS: A significant decrease in serum BAP level was observed in the treatment group compared with the control group. However there were no significant differences in serum levels of PICP and ICTP before or after treatment compared with the control group.CONCLUSION: Yishengukang decoction combined with pamidronate disodium injection reduced serum BAP level to a greater extent that pamidronate disodium injection alone. Furthermore, the combined therapy was more beneficial in regulating imbalanced bone metabolism after bone metastasis,and may represent the molecular mechanism underpinning the effects of Yishengukang decoction. | Yin Yukun Feng Li Zhou Lei Li Jie Gao Yin Wang Ningjun Yu Jianhua Jiang Zhenglong He Shengqi Lu Dianrong Wang Fang Du Yanlin | 2017 | Journal of Traditional Chinese Medicine2017，37，1： | 6 |
| 2 | Flight dynamics modeling of a small ducted fan aerial vehicle based on parameter identifcation显示文摘This paper presents a simple and useful modeling method to acquire a dynamics model of an aerial vehicle containing unknown parameters using mechanism modeling,and then to design different identifcation experiments to identify the parameters based on the sources and features of its unknown parameters.Based on the mathematical model of the aerial vehicle acquired by modeling and identifcation,a design for the structural parameters of the attitude control system is carried out,and the results of the attitude control flaps are verifed by simulation experiments and flight tests of the aerial vehicle.Results of the mathematical simulation and flight tests show that the mathematical model acquired using parameter identifcation is comparatively accurate and of clear mechanics,and can be used as the reference and basis for the structural design. | Wang Zhengjie Liu Zhijun Fan Ningjun Guo Meifang | 2013 | Chinese Journal of Aeronautics2013，26，6： | 5 |
| 3 | Control and dynamics analysis for miniature autogyro and compound autogyro显示文摘Dear editor,An autogyro is a type of aircraft achieving effective low-speed flight and short take-off and landing performance.A compound autogyro is a“pure”autogyro.designed with additional fixed wings.Its rotor ensures effective low-speed flight performance,and because the wings produce most of the lift at high airspeeds many problems associated with high-speed rotor dynamics in pure autogyros(and helicopters by extension)are circumvented [1]. | Zhihao CAI Ningjun LIU Jiang ZHAO Yingxun WANG | 2019 | Science China(Information Sciences)2019，62，1： | 2 |
| 4 | Measurement of Immiscible CO2Flooding Processes and Permeability Reduction due to Asphaltene Precipitation by X-ray CT Imaging显示文摘 | Wang Tonglei Song Yongchen zhao Yuechao Liu Yu and Zhu Ningjun | 2013 | Energy Procedia2013，，： | 1 |
| 5 | Onboard actuator model-based Incremental Nonlinear Dynamic Inversion for quadrotor attitude control:Method and application显示文摘This paper addresses the robust attitude control problem for quadrotors subject to model mismatch and disturbances.A dynamic inversion based attitude control scheme is proposed,which consists of an outer loop attitude controller and an inner loop angular acceleration controller.The attitude controller is designed based on the Nonlinear Dynamic Inversion(NDI)to precisely linearize the nonlinear dynamics between the angular acceleration and the attitude.An onboard actuator model-based Incremental Nonlinear Dynamic Inversion(INDI)controller is designed in the angular acceleration control loop to improve the robustness against the model mismatch and disturbances.Meanwhile,the onboard actuator model with a modified structure eliminates the oscillation phenomenon when the sampling rate of the controller is higher than that of the actuator.Numerical simulations and flight tests demonstrate the effectiveness and robustness of the proposed controller in comparison with the PID controller. | Zexin WANG Jiang ZHAO Zhihao CAI Yingxun WANG Ningjun LIU | 2021 | Chinese Journal of Aeronautics2021，34，11： | 1 |
| 6 | Measurement of Immiscible CO 2 Flooding Processes and Permeability Reduction due to Asphaltene Precipitation by X-ray CT Imaging显示文摘 | Tonglei Wang Yongchen Song Yuechao zhao Yu Liu Ningjun Zhu | 2013 | Energy Procedia2013，，： | 1 |
| 7 | Effects of biochar-amended alkali-activated slag on the stabilization of coral sand in coastal areas显示文摘Coral sand is widely encountered in coastal areas of tropical and subtropical regions.Compared with silica sand,it usually exhibits weaker performance from the perspective of engineering geology.To improve the geomechanical performance of coral sand and meet the requirement of foundation construction in coastal areas,a novel alkali activation-based sustainable binder was developed.The alkaliactivated slag(AAS)binder material was composed of ground granulated blast-furnace slag(GGBS)and hydrated lime with the amendment of biochar,an agricultural waste-derived material.The biocharamended AAS stabilized coral sand was subjected to a series of laboratory tests to determine its mechanical,physicochemical,and microstructural characteristics.Results show that adding a moderate amount of biochar in AAS could improve soil strength,elastic modulus,and water holding capacity by up to 20%,70%,and 30%,respectively.Moreover,the addition of biochar in AAS had a marginal effect on the sulfate resistance of the stabilized sand,especially at high biochar content.However,the resistance of the AAS stabilized sand to wet-dry cycles slightly deteriorated with the addition of biochar.Based on these observations,a conceptual model showing biochar-AAS-sand interactions was proposed,in which biochar served as an internal curing agent,micro-reinforcer,and mechanically weak point. | Xiaole Han Ningjun Jiang Fei Jin Krishna RReddy Yijie Wang Kaiwei Liu Yanjun Du | 2023 | Journal of Rock Mechanics and Geotechnical Engineering2023，15，3： | 0 |
| 8 | Fast level-flight to hover mode transition and altitude control in tiltrotor’s landing operation显示文摘An attempt is made to implement a faster level-flight to hover mode transition in tiltrotor’s landing process for the purpose of shortening its landing time. A three-stage tiltrotor landing maneuver is designed, and corresponding control modules and algorithms are created based on the analysis of the flight dynamics and the required actions of tiltrotor’s landing operation. As the altitude control is vital for tiltrotor’s near-ground landing, an Extended State Observer(ESO) control module of the Active Disturbance Rejection Control(ADRC) is designed to reduce altitude fluctuations in the fast mode transition, which makes the designed maneuver workable at very low altitudes. Simulations are conducted to verify the effectiveness of the designed maneuver and the validity of ESO control in various flight conditions. Flight test results that finally prove the effectiveness of the desired fast transition maneuver are reported. | Ningjun LIU Zhihao CAI Yingxun WANG Jiang ZHAO | 2021 | Chinese Journal of Aeronautics2021，34，1： | 0 |
| 9 | NH_(3)‑Induced In Situ Etching Strategy Derived 3D‑Interconnected Porous MXene/Carbon Dots Films for High Performance Flexible Supercapacitors显示文摘2D MXene(Ti_(3)CNT_(x))has been considered as the most promising electrode material for flexible supercapacitors owing to its metallic conductivity,ultra-high capacitance,and excellent flexibility.However,it suffers from a severe restacking problem during the electrode fabrication process,limiting the ion transport kinetics and the accessibility of ions in the electrodes,especially in the direction normal to the electrode surface.Herein,we report a NH_(3)-induced in situ etching strategy to fabricate 3D-interconnected porous MXene/carbon dots(p-MC)films for high-performance flexible supercapacitor.The pre-intercalated carbon dots(CDs)first prevent the restacking of MXene to expose more inner electrochemical active sites.The partially decomposed CDs generate NH_(3)for in situ etching of MXene nanosheets toward 3D-interconnected p-MC films.Benefiting from the structural merits and the 3D-interconnected ionic transmission channels,p-MC film electrodes achieve excellent gravimetric capacitance(688.9 F g^(-1)at 2 A g^(-1))and superior rate capability.Moreover,the optimized p-MC electrode is assembled into an asymmetric solid-state flexible supercapacitor with high energy density and superior cycling stability,demonstrating the great promise of p-MC electrode for practical applications. | Yongbin Wang Ningjun Chen Bin Zhou Xuefeng Zhou Ben Pu Jia Bai Qi Tang Yan Liu Weiqing Yang | 2023 | Nano-Micro Letters2023，15，12： | 0 |
| 10 | Compressibility characteristics of bio-cemented calcareous sand treated through the bio-stimulation approach显示文摘Calcareous sand is widely present in coastal areas around the world and is usually considered as a weak and unstable material due to its high compressibility and low strength.Microbial-induced calcium carbonate precipitation(MICP)is a promising technique for soil improvement.However,the commonly adopted bio-augmented MICP approach is in general less compatible with the natural soil environment.Thus,this study focuses on the bio-stimulated MICP approach,which is likely to enhance the dominance of ureolytic bacteria for longer period and thus is deemed more efficient.The main objective of this paper is to investigate the compressibility of calcareous sand treated by bio-stimulated MICP approach.In the current study,a series of one-dimension compression tests was conducted on bio-cemented sand pre-pared via bio-stimulation with different initial relative densities(D r).Based on the obtained compression curves and particle size distribution(PSD)curves,the parameters including cementation content,the coefficient of compressibility(a v),PSD,relative breakage(B r),and relative agglomeration(A r)were discussed.The results showed that a v decreased with the increasing cementation content.The bio-cemented sand prepared with higher initial D r had smaller(approximately 20%e70%)a v values than that with lower initial D r.The specimen with higher initial D r and higher cementation content resulted in smaller B r but larger A r.Finally,a conceptual framework featuring multiple contact and damage modes was proposed. | Yijie Wang Ningjun Jiang Alexandra Clarà Saracho Ogul Doygun Yanjun Du Xiaole Han | 2023 | Journal of Rock Mechanics and Geotechnical Engineering2023，15，2： | 0 |
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