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| 1 | 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents显示文摘Syncope belongs to the transient loss of consciousness(TLOC), characterized by a rapid onset, short duration, and spontaneous complete recovery. It is common in children and adolescents, accounting for 1% to 2% of emergency department visits.Recurrent syncope can seriously affect children's physical and mental health, learning ability and quality of life and sometimes cardiac syncope even poses a risk of sudden death. The present guideline for the diagnosis and treatment of syncope in children and adolescents was developed for guiding a better clinical management of pediatric syncope. Based on the globally recent development and the evidence-based data in China, 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents was jointly prepared by the Pediatric Cardiology Society, Chinese Pediatric Society, Chinese Medical Association(CMA)/Committee on Pediatric Syncope, Pediatricians Branch, Chinese Medical Doctor Association(CMDA)/Committee on Pediatric Cardiology, Chinese College of Cardiovascular Physicians, Chinese Medical Doctor Association(CMDA)/Pediatric Cardiology Society, Beijing Pediatric Society, Beijing Medical Association(BMA). The present guideline includes the underlying diseases of syncope in children and adolescents, the diagnostic procedures, methodology and clinical significance of standing test and headup tilt test, the clinical diagnosis vasovagal syncope, postural orthostatic tachycardia syndrome, orthostatic hypotension and orthostatic hypertension, and the treatment of syncope as well as follow-up. | Cheng Wang Yaqi Li Ying Liao Hong Tian Min Huang Xiangyu Dong Lin Shi Jinghui Sun Hongfang Jin Junbao Du Jindou An Jie Chen Mingwu Chen Qi Chen Sun Chen Yonghong Chen Zhi Chen Adolphus Kai-tung Chau Junbao Du Zhongdong Du Junkai Duan Hongyu Duan Xiangyu Dong Lin Feng Lijun Fu Fangqi Gong Yonghao Gui Ling Han Zhenhui Han Bing He Zhixu He Xiufen Hu Yimin Hua Guoying Huang Min Huang Ping Huang Yujuan Huang Hongfang Jin Mei Jin Bo Li Fen Li Tao Li Xiaohui Li Xiaoyan Liu Yan Li Haitao Lv Tiewei Lv Zipu Li Luyi Ma Silin Pan Yusheng Pang Hua Peng Yuming Qin Jie Shen Lin Shi Kun Sun Jinghui Sun Hong Tian Jie Tian Cheng Wang Hong Wang Lei Wang Jinju Wang Wendi Wang Yuli Wang Rongzhou Wu Tianhe Xia Yanyan Xiao Chunhong Xie Yanlin Xing Zhenyu Xiong Baoyuan Xu Yi Xu Hui Yan Shiwei Yang Qijian Yi Xia Yu Xianyi Yu Yue Yuan Hongyan Zhang Huili Zhang Li Zhang Qingyou Zhang Xi Zhang Yanmin Zhang Zhiwei Zhang Cuifen Zhao Bin Zhou Hua Zhu | 2018 | Science Bulletin2018，63，23： | 54 |
| 2 | Basement of the South China Sea Area:Tracing the Tethyan Realm显示文摘华南海( SCS )和邻近的区域的地下室能被划分成六个部门(区域)在 Beibu 海湾的古生代的 Erathem 指责graben 的地下室分割,在 Yinggehai 的古生代的 Erathem 罢工滑倒拉开流水,在东方海南的古生代的 Erathem 差错消沉,在北 Xisha ( Paracel )的古生代的 Erathem rifted ,古生代的 Erathem 罢工滑倒在在 Nansha 岛延长的南部的 Xisha ,和古生代中生代的 Erathem 延长( Spratly )水。在 SCS 和 Yunkai 大陆人区域的新生代前地下室在在新生代前时期的 Tethyan 构造领域以内是同时代的。他们在 Paleo-Tethyan 构造领域的背景上被形成,并且是东方 Tethyan multi-island-ocean 系统的重要部件。东方 Paleo-Tethys 构造领域,北方 Yunkai,诺思海南,和南方海南海盆的三个分支,演变为北方 Yunkai,诺思海南,和南方海南缝术地区分别地。这为新生代前地下室显示出本地化的一个特殊特征。 Qiongnan (即南方海南)华南海的北边缘上的缝术地区能被认为 Paleo-Tethys 的主要海洋盆的痕迹,并且与 Longmucuo-Shuanghu beltBitu 带 Changning-Menglian-Bentong-Raub 带的缝术地区连接了,华南海的西方上的 Bitu-Changning-MenglianChing Mai beltChanthaburi-Raub-Bentong 带的南方延期,并且与 Lianhua-Taidong 缝术地区(沿着在台湾的纵的山谷的东方方面的一个差错) Hida Qiongbei (诺思海南) 缝术地区可以向东沿着 Wangwu-Wenjiao 差错地区延长了,并且深与 Lufeng-Dapu-Zhenghe-Shangyu (Lianhuashan ) 连接通过珍珠河嘴盆的差错地区。Meso-Tethys 在华南海的南方上发展了。Nansha 马槽可以被认为 Meso-Tethys 的北架的痕迹。 Meso-Tethys 的海洋的外壳向南沿着 subduction-collision-thrust 有 subducted 有华南海的西方上的 Yarlung Zangbo-Mytkyina-Bago 地区的到那些的subduction杆反面的 Nansha 马槽的南部的边缘,并且 Meso-Tethyan (例如 Meso-Tethys 的北 Chichibu 海洋)在在西南日本的侏罗记早的白垩纪地球组的外部带的缝术地区 Butsozo 构造的线,在华南海的东方上。 | LIU Hailing ZHENG Hongbo WANG Yanlin LIN Qiujin WU Chaohua ZHAO Meisong DU Yunkong | 2011 | Acta Geologica Sinica(English Edition)2011，85，3： | 13 |
| 3 | Characteristics and Morbidity of the Tuberculosis Epidemic--China,2019显示文摘Introduction:The year 2019 was crucial for the implementation of China’s National“13th 5-Year”Tuberculosis(TB)Control Plan.We conducted this study to evaluate the characteristics and progress towards controlling TB in China.Methods:We collected and analyzed the pulmonary tuberculosis(PTB)data of China between January 1,2015 and December 31,2019 from the National Notifiable Disease Reporting System(NNDRS).Results:In 2019,there were 775,764 PTB cases reported in NNDRS,of which 349,307 were bacteriologically-confirmed(Bac+)cases.The PTB case notification rate(CNR)was 55.55 per 100,000,and the Bac+CNR was 25.01 per 100,000.From 2018 to 2019,the number of PTB cases fell by 6.3%,but the number of Bac+cases increased by 25.9%.The annual decrease in the rate of reported PTB was 3.4% from 2015 to 2019.The 5 provincial-level administrative divisions(PLADs)with the highest PTB CNR were as follows:Tibet(182.38 per 100,000),Xinjiang(169.05 per 100,000),Qinghai(134.53 per 100,000),Guizhou(102.51 per 100,000),and Hainan(90.22 per 100,000).The rate of reported PTB was 74.84 per 100,000 for males and 35.40 per 100,000 for females.There were 8,116 cases(1.0%)among children aged 0–14 years,and 197,730 cases(25.5%)among adults aged 65 years and over.Of the reported cases,470,932 were farmers,which was the most common occupation at 60.7%.Conclusions and Implications for Public Health Practice:The TB epidemic has decreased dramatically year by year.Most PTB cases were in the central and western regions of China,and the high-risk groups were farmers and elderly people aged 65 years and over. | Wei Chen Hui Zhang Xin Du Tao Li Yanlin Zhao | 2020 | China CDC weekly2020，2，12： | 13 |
| 4 | Effects of Yishengukang decoction on expression of bone-specific alkaline phosphatase,carboxyterminal propeptide of typeⅠprocollagen,and carboxyterminal cross-linked telepeptide of typeⅠcollagen in malignant tumor patients with bone metastasis显示文摘OBJECTIVE: To investigate the effect of Yishengukang decoction on the expression of the metabolic bone markers, bone-specific alkaline phosphatase(BAP), carboxyterminal propeptide of type Ⅰ procollagen(PICP), and carboxyterminal cross-linked telepeptide of type Ⅰ collagen(ICTP), in cancer patients with bone metastasis.METHODS: Patients(n = 180) were divided into three groups:(a) bone metastasis patients treated with Yishengukang and pamidronate disodium injection(treatment group, n = 60);(b) bone metastasis patients treated with pamidronate disodium injection alone(control group, n = 60);(c) cancer patients without metastatic bone lesion(non-bone metastasis group, n = 60). Serum levels of the metabolic markers BAP, PICP, and ICTP were detected by enzyme-linked immunosorbent assay pre- and post-therapy.RESULTS: A significant decrease in serum BAP level was observed in the treatment group compared with the control group. However there were no significant differences in serum levels of PICP and ICTP before or after treatment compared with the control group.CONCLUSION: Yishengukang decoction combined with pamidronate disodium injection reduced serum BAP level to a greater extent that pamidronate disodium injection alone. Furthermore, the combined therapy was more beneficial in regulating imbalanced bone metabolism after bone metastasis,and may represent the molecular mechanism underpinning the effects of Yishengukang decoction. | Yin Yukun Feng Li Zhou Lei Li Jie Gao Yin Wang Ningjun Yu Jianhua Jiang Zhenglong He Shengqi Lu Dianrong Wang Fang Du Yanlin | 2017 | Journal of Traditional Chinese Medicine2017，37，1： | 6 |
| 5 | Prevalence of Metabolic Syndrome and Risk Factors Among Chinese Adults:Results from a Population-Based Study—Beijing,China,2017–2018显示文摘Summary What is already known about this topic?Metabolic syndrome(MetS)is one of the most easily available health indicative markers for cardiovascular diseases,and it has become a major public health problem worldwide due to increasing urbanization and aging populations.The prevalence of MetS increased dramatically in China,however,there are no records of MetS defined by the 2017 Chinese Diabetes Society for Beijing by far.What is added by this report?In this study,the data of 24,412 participants aged 18–74 years from a large population-based study in Beijing was collected.The overall prevalence of MetS among Beijing residents was 24.5%.The prevalence was 35.2%in males and 15.4%in females.What are the implications for public health practice?Effective public health strategies should target males,people with older age,lower education,higher body mass index,smokers,those who drink alcohol,those who are unemployed or retired,and those who live in rural areas on MetS prevention and control. | Jufen Liu Qingping Liu Zhiwen Li Jing Du Chao Wang Yanlin Gao Zaihua Wei Jing Wang Yunping Shi Jianting Su Yang Liu Ping Wang Chunyan Xie Gang Li Bing Shao Le Zhang | 2022 | China CDC weekly2022，4，29： | 4 |
| 6 | Substantial transition to clean household energy mix in rural China显示文摘The household energy mix has significant impacts on human health and climate,as it contributes greatly to many health-and climate-relevant air pollutants.Compared to the well-established urban energy statistical system,the rural household energy statistical system is incomplete and is often associated with high biases.Via a nationwide investigation,this study revealed high contributions to energy supply from coal and biomass fuels in the rural household energy sector,while electricity comprised∼20%.Stacking(the use of multiple sources of energy)is significant,and the average number of energy types was 2.8 per household.Compared to 2012,the consumption of biomass and coals in 2017 decreased by 45%and 12%,respectively,while the gas consumption amount increased by 204%.Increased gas and decreased coal consumptions were mainly in cooking,while decreased biomass was in both cooking(41%)and heating(59%).The time-sharing fraction of electricity and gases(E&G)for daily cooking grew,reaching 69%in 2017,but for space heating,traditional solid fuels were still dominant,with the national average shared fraction of E&G being only 20%.The non-uniform spatial distribution and the non-linear increase in the fraction of E&G indicated challenges to achieving universal access to modern cooking energy by 2030,particularly in less-developed rural and mountainous areas.In some non-typical heating zones,the increased share of E&G for heating was significant and largely driven by income growth,but in typical heating zones,the time-sharing fraction was<5%and was not significantly increased,except in areas with policy intervention.The intervention policy not only led to dramatic increases in the clean energy fraction for heating but also accelerated the clean cooking transition.Higher income,higher education,younger age,less energy/stove stacking and smaller family size positively impacted the clean energy transition. | Guofeng Shen Rui Xiong Yanlin Tian Zhihan Luo Bahabaike Jiangtulu Wenjun Meng Wei Du Jing Meng Yuanchen Chen Bing Xue Bin Wang Yonghong Duan Jia Duo Fenggui Fan Lei Huang Tianzhen Ju Fenggui Liu Shunxin Li Xianli Liu Yungui Li Mu Wang Ying Nan Bo Pan Yanfang Pan Lizhi Wang Eddy Zeng Chao Zhan Yilin Chen Huizhong Shen Hefa Cheng Shu Tao | 2022 | National Science Review2022，9，7： | 4 |
| 7 | Underreporting of Notifiable Pulmonary Tuberculosis Cases to the National Tuberculosis Information Management System--China,2015显示文摘What is already known about this topic?Tuberculosis(TB)notification data and the underreporting rate are major sources used in estimating TB incidence.China’s TB Information Management System(TBIMS)was launched in 2005 but has not yet been evaluated for sensitivity.What is added by this report?The average underreporting rate of pulmonary TB to TBIMS in selected facilities was 8.23%.However,provincial TB or infectious disease-specific health facilities,or general health facilities had higher underreporting rates.Children,migrants,and drug resistant TB patients had higher chances to be underreported than other populations.What are the implications for public health practice?Underreporting surveys should be routinely implemented in the future.This will be vital for enhancing TB reporting and the transfer mechanisms in TB or infectious disease-specific hospitals,or general hospitals and improving the case information registration procedures in designated health facilities(DHFs). | Tao Li Wei Chen Yanlin Zhao Lixia Wang Mingting Chen Xin Du Hui Zhang | 2020 | China CDC weekly2020，2，12： | 4 |
| 8 | Implementation Performance of Tuberculosis Controlin China:2011-2020显示文摘Summary What is already known about this topic?World Health Organization(WHO)launched ENDTB Strategy but performance of tuberculosis(TB)control in China hasn’t been systematically evaluatedafter 2010.What is added by this report?All five key indicators monitorred in national TBprogram(NTP)have kept with high level or gotimpressively improved from 2011 to 2020.There weresome differences in the performance of indicatorsamong different regions. | Tao Li Xin Du Xiaoqiu Liu Yuhong Li Yanlin Zhao | 2021 | China CDC weekly2021，3，12： | 2 |
| 9 | The Impact of COVID-19 on Tuberculosis Patients’Behavior of Seeking Medical Care——China,2020显示文摘Summary What is already known on this topic?The coronavirus disease 2019(COVID-19)pandemic has disrupted the tuberculosis(TB)service system.However,the impact on TB patients in China remains unknown.What is added by this report?This report firstly addressed the impact of COVID-19 on TB patients in China.About half of TB patients did not revisit the hospital due to personal reasons.The reasons for irregular medication and postponing or cancelling examination after full treatment course were different. | Yinyin Xia Fei Huang Hui Chen Ni Wang Xin Du Wei Chen Tao Li Shitong Huan Miaomiao Sun Jianjun Liu Yanlin Zhao | 2021 | China CDC weekly2021，3，26： | 2 |
| 10 | Health Facilities and Treatment Service Models of the National Tuberculosis Program—China,2010−2020显示文摘Summary What is already known about this topic?A new tuberculosis(TB)treatment service model called“trinity model”has been adopted in China since 2010 but the implementation coverage is still unknown.What is added by this report?In 2020,more than one-third(36.5%)of health facilities diagnosed less than 100 TB cases,about onefourth(25.5%)diagnosed 100 to 200 cases,and 94 health facilities diagnosed more than 800 cases. | Xin Du Tao Li Xiaoqiu Liu Yanlin Zhao | 2021 | China CDC weekly2021，3，13： | 2 |
| 11 | Small molecule SMU-CX24 targeting toll-like receptor 3 counteracts inflammation:A novel approach to atherosclerosis therapy显示文摘Toll-like receptor 3(TLR3),as an important pattern recognition receptor(PRR),dominates the innate and adaptive immunity regulating many acute and chronic inflammatory diseases.Atherosclerosis is proved as an inflammatory disease,and inflammatory events involved in the entire process of initiation and deterioration.However,the contribution of TLR3 to atherosclerosis remains unclear.Herein,we identified the clinical relevance of TLR3 upregulation and disease processes in human atherosclerosis.Besides,activation of TLR3 also directly led to significant expression of atherogenic chemokines and adhesion molecules.Conversely,silencing TLR3 inhibited the uptake of oxLDL by macrophages and significantly reduced foam cell formation.Given the aberrance in TLR3 functions on atherosclerosis progression,we hypothesized that TLR3 could serve as novel target for clinical atherosclerosis therapy.Therefore,we developed the novel ellipticine derivative SMU-CX24,which specifically inhibited TLR3(IC_(50)=18.87±2.21 nmol/L).In vivo,atherosclerotic burden was alleviated in Western diet fed ApoE^(−/−)mice in response to SMU-CX24 treatment,accompanying notable reductions in TLR3 expression and inflammation infiltration within atherosclerotic lesion.Thus,for the first time,we revealed that pharmacological downregulation of TLR3 with specific inhibitor regenerated inflammatory environment to counteract atherosclerosis progression,thereby proposing a new strategy and probe for atherosclerosis therapy. | Xiaohong Cen Baoqu Wang Yuqing Liang Yanlin Chen Yu Xiao Shaohua Du Kutty Selva Nandakumar Hang Yin Shuwen Liu Kui Cheng | 2022 | Acta Pharmaceutica Sinica B2022，12，9： | 2 |
| 12 | Patient,Diagnosis,and Treatment Delays Among Tuberculosis Patients Before and During COVID-19 Epidemic—China,2018-2022显示文摘Summary What is already known about this topic?The coronavirus disease(COVID-19)pandemic could have a damaging impact on access to tuberculosis(TB)diagnosis and treatment.What is added by this report?The overall delay experienced by TB patients during the COVID-19 pandemic has shown a modest decrease in comparison to the period before the pandemic.Notably,higher patient delays were observed among agricultural workers and those identified through passive case-finding methods.Furthermore,the patient delay in eastern regions was shorter compared to western and central regions. | Tao Li Xin Du Jiaojie Kang Dan Luo Xiaoqiu Liu Yanlin Zhao | 2023 | China CDC weekly2023，5，12： | 1 |
| 13 | Effectiveness of the Integrated TB Surveillance System--China,2018-2019显示文摘What is already known about this topic?China’s national health information system provides important support and means for deepening the country’s medical and health reform,for improving relevant delivery services,for enhancing the level of scientific management of health,and for promoting the goal of basic medical and health services for everyone in China.What is added by this report?To further the construction of the national health information system,the National Center for Tuberculosis Control and Prevention of China CDC,started a pilot project for a new tuberculosis(TB)integrated health(iHealth)surveillance system,which was integrated with regional health information platforms.The goal was to explore automatic data exchange between hospitals and disease control facilities to reduce the workload of data-entry.What are the implications for public health practice?This pilot proved that data sharing and automatic exchanges between different information systems can be achieved through a unified surveillance dataset,which could provide a reference point for the construction of surveillance systems for other infectious diseases or for the entire public health information system. | Ni Wang Tao Li Xin Du You Li Miaomiao Sun Shitong Huan Hui Zhang Lixia Wang Mingting Chen Fei Huang Yanlin Zhao | 2020 | China CDC weekly2020，2，12： | 1 |
| 14 | A new green technology for direct production of low molecular weight chitosan 显示文摘 | Weiping Wang Yumin Du Yanlin Qiu | 2008 | Carbohydrate Polymers2008，74，： | 1 |
| 15 | Age-Specific Pulmonary Tuberculosis Notification Rates—China,2008–2018显示文摘What is already known about this topic?The incidence of tuberculosis(TB)was declining in China but has plateaued in recent years.What is added by this report?Notifications of pulmonary TB declined by 27.7%between 2008 and 2018,with an average crude decline of 3.4%per year and an average age-adjusted decline of 4.3%per year.Notifications decreased faster among older people,but slower in western China;the combination of trends led to an inflection in 2016 in the overall notification trend from decreasing to stable.What are the implications for public health practice?Population ageing and geographic disparities slowed tuberculosis control progress in China.Enhanced,targeted,and proactive responses are recommended to achieve the End TB targets. | Tao Li Jun Li Xin Du Qiang Sun Lixia Wang Yanlin Zhao Fei Huang Ni Wang Kui Yang Wei Chen Hui Zhang | 2022 | China CDC weekly2022，4，38： | 1 |
| 16 | A new green technology for direct production of low molecular weight ehitosan 显示文摘 | WANG Weiping DU /umin QIU Yanlin | 2008 | Carbohydrate Polymers2008，74，1： | 1 |
| 17 | Synthesis of Super - high Molecular Weight Polyacrylamides and Their Floccu- lation Properties 显示文摘 | Yanlin Sun Huixiang Du Hong Wang | 2012 | Advanced Materials Research2012，，： | 1 |
| 18 | Effects of Polyacrylamide Mixtures with Different Molecular Weights on Sedi- mentation of Red Mud 显示文摘 | Huixiang Du Yanlin Sun Hong Wang | 2012 | Advanced Materials Research2012，，： | 1 |
| 19 | Colorimetric detection of hepatitis E virus based on reverse transcription loop mediated isother- mal amplification (RT-LAMP) assay显示文摘 | Chen Qiuhua Yuan Lu Wan Jun Chen Yanlin Du Chaoyang | 2014 | Journal of Virological Methods2014，197，： | 1 |
| 20 | A Questionnaire Survey on Extrapulmonary Tuberculosis Control and Prevention—China,2021显示文摘Summary What is already known about this topic?Tuberculosis(TB)is a multisystem disease that might affect any organ.Currently,the National TB Program(NTP)issued by the State Council of China,only covers pulmonary tuberculosis(PTB),and the status of extrapulmonary tuberculosis(EPTB)remains unclear nationwide.What is added by this report?The survey conducted by China CDC reported that there were no specific health facilities responsible for diagnosis,treatment and management of EPTB in China,while more than half of counties thought it should be included into NTP. | Mingzhe Wang Ni Wang Ni Ni Tao Li Lin Zhou Xin Du Yanlin Zhao Fei Huang | 2023 | China CDC weekly2023，5，8： | 0 |
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