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| 1 | Outline of the Report on Cardiovascular Disease in China,2010显示文摘Major and profound changes have taken place in China over the past 30 years.Rapid socioeconomic progress has exerted a great impact on lifestyle,ranging from food,clothing,working and living conditions,and means of transportation to leisure activities and entertainment.At the same time,new health problems have emerged,and health services are facing new challenges.Presently,cardiovascular diseases (CVD) are among the top health problems of the Chinese people,and pose a serious challenge to all engaged in the prevention and control of these diseases.An epidemic of CVD in China is emerging as a result of lifestyle changes,urbanization and longevity.Both national policy decision-making and medical practice urgently need an authoritative report which comprehensively reflects the trends in the epidemic of CVD and current preventive measures.Since 2005,guided by the Bureau of Disease Prevention of the Ministry of Health of the People's Republic of China and the National Center for Cardiovascular Diseases of China,nationwide experts in the fields of epidemiology,clinical medicine and health economics in the realms of CVD,cerebrovascular disease,diabetes and chronic kidney disease,completed the Report on Cardiovascular Diseases in China every year.The report aims to provide a timely review of the trend of the epidemic and to assess the progress of prevention and control of CVD.In addition,as the report is authoritative,representative and readable,it will become an information platform in the CVD field and an important reference book for government,academic institutes,medical organizations and clinical physicians.This publication is expected to play a positive role in the prevention and control of CVD in China.We present an abstract from the Report on Cardiovascular Diseases in China (2010),including trends in CVD,morbidity and mortality of major CVDs,up-to-date assessment of risk factors,as well as health resources for CVD,and a profile of medical expenditure,with the aim of providing evidence for decision-making in CVD prevention and control programs in China,and of delivering the most authoritative information on CVD prevention and control for all citizens. | HUSheng Shou KONG Ling Zhi GAO Run Lin ZHU Man Lu WANG Wen WANG Yong Jun WU Zhao Su CHEN Wei Wei LIU Ming Bo For the editorial board | 2012 | Biomedical and Environmental Sciences2012，25，3： | 93 |
| 2 | Summary of Report on Cardiovascular Diseases in China,2012显示文摘The prevalence of cardiovascular diseases(CVDs)is associated with the socioeconomic prosperity,lifestyle changes,accelerated process of ageing and urbanization.The prevalence of CVDs is continuously increasing in China and will remain an upward trend in the next 10 years.CVDs are the leading cause of death for Chinese in both urban area and rural area. | WANG Wen HU Sheng Shou KONG Ling Zhi GAO Run Lin ZHU Man Lu WANG Yong Jun WU Zhao Su CHEN Wei Wei YANG Jin Gang MALi Yuan LIU Ming Bo For the editorial board | 2014 | Biomedical and Environmental Sciences2014，27，7： | 31 |
| 3 | Construction of a cucumber genetic linkage map with SRAP markers and location of the genes for lateral branch traits显示文摘Using SRAP (sequence-related amplified polymorphism) markers a genetic linkage map of cucumber was constructed with a population consisting of 138 F2 individuals derived from a cross of the two cucumber lines, S06 and S52. In the survey of parental polymorphisms with 182 primer combinations, 64 polymorphism-revealing primer pairs were screened out, which generated totally 108 polymorphic bands with an average of 1.7 bands per primer pair and at most 6 bands from one primer pair. The constructed molecular linkage map included 92 loci, distributed in seven linkage groups and spanning 1164.2 cM in length with an average genetic distance of 12.6 cM between two neighboring loci. Based on this linkage map, the quantitative trait loci (QTL) for the lateral branch number (lbn) and the lateral branch average length (lbl) in cucumber were identified by QTLMapper1.6. A major QTL lbn1 located between ME11SA4B and ME5EM5 in LG2 could explain 10.63% of the total variation with its positively effecting allele from S06. A major QTL lbl1 located between DC1OD3 and DC1EM14 in LG2 could account for 10.38% of the total variation with its positively effecting allele from S06. | WANG Gang PAN Junsong LI Xiaozun HE Huanle WU Aizhong CAI Run | 2005 | Science China(Life Sciences)2005，48，3： | 24 |
| 4 | High-resolution geochemistry records of climate changes since late-glacial from Dajiuhu peat in Shennongjia Mountains,Central China显示文摘A peat core with depths of 297 cm was obtained from the Dajiuhu Basin(31°29′27″N,109°59′45″E,1760 m)in Hubei Province,Central China.10 AMS ages provide a time control and reveal that this core spans the past about 16.0 kaBP(calibrated age)(1 4C age:13.3 kaBP).Multi-proxy indexes analysis of geochemistry shows the following character of climate and environmental changes since about 16 kaBP:(1) The climate during the late-glacial period was cold and wet as a whole,but fluctuated continually.11.4- 12.6 cal.kaBP,12.6-15.2 cal.kaBP and 15.2-16 kaBP were corresponding respectively to the Younger Drays,Bφlling-Allerφd Warm Period and the Oldest Drays.(2)Inheriting the some climate characteristics of the late-glacial,the climate during the early-Holocene was wet and temperature increased gradually,during which an obvious dry event around 10.6 cal.kaB appeared.(3)The climate during the mid-Holocene was genarally warm and wet.During 9.2-7.5 kaBP,temperature increased gradually, precipitation was less comparatively and the 8.2 kaBP cold event which might be representative in the globe was reflected markedly.Then,multi-proxy records were relatively stable during 6.7-4.2 kaBP, which shows the best water and thermal condition in the Holocene Optimum.(4)Around 4.2 kaBP,the climate and environment transform from warm and wet to cool and dry,which may result in the collapse of the Neolithic Culture and midwifery the civilization of Xia Dynasty in this region.After 0.9 kaBP,the climate turned cool and wet.Climate and environmental changes archived in Dajiuhu peat respond to the global changes since the late-glacial period and can be contrasted to the changes recorded in other high-resolution archives from the East Asia Monsoon region,which take on the variety model that the monsoon strengthened abruptly after the late-glacial,was strong during the early Holocene,subse- quently declined and became weak after the middle Holocene with dry climate.According to our analysis,the driving mechanism should be the response of solar radiation changes in the East Asia Monsoon region at middle latitudes. | MA ChunMei ZHU Cheng ZHENG ChaoGui WU ChunLin GUAN Yong ZHAO ZhiPing HUANG LinYan HUANG Run | 2008 | Chinese Science Bulletin2008，53，S1： | 19 |
| 5 | Template-free large-scale synthesis of g-C3N4 microtubes for enhanced visible light-driven photocatalytic H2 production显示文摘 | Chao Zhou Run Shi Lu Shang Li-Zhu Wu Chen-Ho Tung Tierui Zhang | 2018 | Nano Research2018，11，6： | 17 |
| 6 | Supramolecular precursor strategy for the synthesis of holey graphitic carbon nitride nanotubes with enhanced photocatalytic hydrogen evolution performance显示文摘A simple one-step thermal polymerization method was developed for synthesis of holey graphitic carbon nitride nanotubes,involving direci eating of mixtures of melamine and urea or melamine and cyanuric acid in specific mass ratios.Supramolecular structures formed betweer the precursor molecules guided nanotube formation.The porous and nanotubular structure of the nanotubes facilitated efficient charge carrier nigration and separation,thereby enhancing photocatalytic Hz production in 20 vol.%lactic acid under visible light irradiation.Nanotubes synthesized using melamine and urea in a 1:10 mass ratio(denoted herein as CN-MU nanotubes)exhibited a photocatalytic hydroger production rate of 1,073.6μmol·h^-1·^-g with Pt as the cocatalyst,a rate of 4.7 and 3.1 times higher than traditional Pt/g-CN4 photocatalysts prepared from graphitic carbon nitride(g-CN4)obtained by direct thermal polymerization of melamine or urea,respectively.On the basis of their outstanding performance for photocatalytic H2 production,it is envisaged that the holey g-C3N4 nanotubes will find widespread uptake in other areas,including photocatalytic CO2 reduction,dye-sensitized solar cells and photoelectrochemical sensors. | Xiaoshuai Wang Chao Zhou Run Shi Qinqin Liu Geoffrey I. N. Waterhouse Lizhu Wu Chen-Ho Tung Tierui Zhang | 2019 | Nano Research2019，12，9： | 15 |
| 7 | RAB31 marks and controls an ESCRT-independent exosome pathway显示文摘Exosomes are generated within the multivesicular endosomes(MVEs)as intraluminal vesicles(ILVs)and secreted during the fusion of MVEs with the cell membrane.The mechanisms of exosome biogenesis remain poorly explored.Here we identify that RAB31 marks and controls an ESCRT-independent exosome pathway.Active RAB31,phosphorylated by epidermal growth factor receptor(EGFR),engages flotillin proteins in lipid raft microdomains to drive EGFR entry into MVEs to form ILVs,which is independent of the ESCRT(endosomal sorting complex required for transport)machinery.Active RAB31 interacts with the SPFH domain and drives ILV formation via the Flotillin domain of flotillin proteins.Meanwhile,RAB31 recruits GTPase-activating protein TBC1D2B to inactivate RAB7,thereby preventing the fusion of MVEs with lysosomes and enabling the secretion of ILVs as exosomes.These findings establish that RAB31 has dual functions in the biogenesis of exosomes:driving ILVs formation and suppressing MVEs degradation,providing an exquisite framework to better understand exosome biogenesis. | Denghui Wei Weixiang Zhan Ying Gao Liyan Huang Run Gong Wen Wang Ruhua Zhang Yuanzhong Wu Song Gao Tiebang Kang | 2021 | Cell Research2021，31，2： | 12 |
| 8 | Nanoparticle-immersed paper imprinting mass spectrometry imaging reveals uptake and translocation mechanism of pesticides in plants显示文摘Design and discovery of carrier-mediated modified pesticides are vital for reducing pesticide dosage and increasing utilization,yet it remains a great challenge due to limited insights into plant translocation mechanisms.Nanostructure/nanoparticle assisted laser desorption/ionization strategy has established itself as a preferential analytical tool for biological tissue analysis,whereas potential applications in plant sciences are hindered with regard to the inability to slice plant leaves and petals.Herein,we report gold nanoparticle(AuNP)-immersed paper imprinting mass spectrometry imaging(MSI)for the spatiotemporal visualization of pesticide translocation in plant leaves.This approach plays a dual role in preserving spatial information and improving ionization efficiency for pesticides regardless of imaging artifacts due to homogenous AuNP deposition.Using this MSI platform,we proposed the elaborate plant translocation mechanism of agrochemicals for the first time,which is currently poorly understood.The dynamic processes of carrier-mediated pesticides can be clearly visualized,including crossing of plasma membranes by transporters,translocation downward in stems through the phloem,diffusion to the xylem and,conversely,accumulation at margins of the treated leaves.Moreover,this AuNP-assisted paper imprinting method could be highly compatible with laser-based MSI instruments,expediting researches across a broad range of fields,especially in nanomaterial development and life sciences. | Xinzhou Wu Run Qin Hanxiang Wu Guangkai Yao Yue Zhang Ping Li Yizhu Xu Zhixiang Zhang Zhibin Yin Hanhong Xu | 2020 | Nano Research2020，13，3： | 8 |
| 9 | Biochemical sensing in graphene-enhanced microfiber resonators with individual molecule sensitivity and selectivity显示文摘Photonic sensors that are able to detect and track biochemical molecules offer powerful tools for information acquisition in applications ranging from environmental analysis to medical diagnosis.The ultimate aim of biochemical sensing is to achieve both quantitative sensitivity and selectivity.As atomically thick films with remarkable optoelectronic tunability,graphene and its derived materials have shown unique potential as a chemically tunable platform for sensing,thus enabling significant performance enhancement,versatile functionalization and flexible device integration.Here,we demonstrate a partially reduced graphene oxide(prGO)inner-coated and fiber-calibrated Fabry-Perot dye resonator for biochemical detection.Versatile functionalization in the prGO film enables the intracavity fluorescent resonance energy transfer(FRET)to be chemically selective in the visible band.Moreover,by measuring the intermode interference via noise canceled beat notes and locked-in heterodyne detection with Hz-level precision,we achieved individual molecule sensitivity for dopamine,nicotine and single-strand DNA detection.This work combines atomic-layer nanoscience and high-resolution optoelectronics,providing a way toward high-performance biochemical sensors and systems. | Zhongxu Cao Baicheng Yao Chenye Qin Run Yang Yanhong Guo Yufeng Zhang Yu Wu Lei Bi Yuanfu Chen Zhenda Xie Gangding Peng Shu-Wei Huang Chee Wei Wong Yunjiang Rao | 2019 | Light(Science & Applications)2019，8，1： | 8 |
| 10 | Construction of a BAC library from cucumber (Cucumis sativus L.) and identification of linkage group specific clones显示文摘A bacterial artificial chromosome (BAC) library consisting of 19,200 clones with an average insert size of 105 kb has been constructed from a cucumber (Cucumis sativus L.) inbred line S94,derived from a cultivar in North China. The entire library was equivalent to approximately 5 haploid cucumber genomes. To facilitate chromosome engineering and anchor the cucumber genetic linkage map to its chromosomes,15 sequence-characterized ampli?ed regions (SCAR) and seven simple sequence repeats (SSR) markers from each link-age group of cucumber were used to screen an ordered array of pooled BAC DNA with polymerase chain reaction (PCR). Fifteen mark-ers gave at least two positive clones. As a result,22 BAC clones representing 7 linkage groups of cucumber were identified,which further validated the genome coverage and utility of the library. This BAC library and linkage group specific clones provide essential resources for future research of the cucumber genome. | Yuan Guan Qi Chen Junsong Pan Zheng Li Huanle He Aizhong Wu Rentao Song Run Cai | 2008 | Progress in Natural Science:Materials International2008，18，2： | 7 |
| 11 | Prospective study of scoring system in selective intraoperative cholangiography during laparoscopic cholecystectomy显示文摘AIM: To evaluate of scoring system in predicting choledocholithiasis in selective intraoperative cholangiography (IOC) during laparoscopic cholecystectomy (LC).METHODS: The scoring system of predicting choledocholithiasis was developed during the retrospective study in 264 cases, and was tested in 184 to evaluate its predictive value in choledocholithiasis.RESULTS: The scoring system was developed in a retrospective study of 264 cases, the statistical analyses showed the predictive factors included sex, transaminase levels, alkaline phosphatase level, bilirubin level, and common bile duct diameter on ultrasonography. The scoring system was used in 184 cases prospectively, of which, 3 of 162 (1.9%) cases scoring <3 had choledocholithiasis, 17 of 22 (77.3 %) cases scores≥3 had choledocholithiasis. A case of scores≥3 or more prospectively should be considered highly intraoperative cholangiography during laparoscopic cholecystectomy.CONCLUSION: The scoring system can predict choledocholithiasis and is helpful in selection patietns for intraoperative cholangiography. | Xiao-Dong Sun Xiao-Yan Cai Jun-Da Li Xiu-Jun Cai Yi-Ping Mu Jin-Min Wu Department of General Surgery,The Affiliated Sir Run Run Shaw Hospital,Zhejiang University Medical College,Hangzhou 310016,Zhejiang Province,China | 2003 | World Journal of Gastroenterology2003，9，4： | 7 |
| 12 | Rational development of a human antibody cocktail that deploys multiple functions to confer Pan-SARS-CoVs protection显示文摘Structural principles underlying the composition and synergistic mechanisms of protective monoclonal antibody cocktails are poorly defined.Here,we exploited antibody cooperativity to develop a therapeutic antibody cocktail against SARS-CoV-2.On the basis of our previously identified humanized cross-neutralizing antibody H014,we systematically an a lyzed a fully human n aive antibody library and rationally identified a potent neutralizing antibody partner,P17,which confers effective protection in animal model.Cryo-EM studies dissected the nature of the P17 epitope,which is SARS-CoV-2 specific and distinctly different from that of HOI4.High-resolution structure of the SARS-CoV-2 spike in complex with HOM and P17,together with functional investigations revealed that in a two-antibody cocktail,synergistic neutralization was achieved by S1 shielding and conformational locking,thereby blocking receptor attachment and viral membrane fusion,conferring high potency as well as robustness against viral mutation escape.Furthermore,cluster analysis identified a hypothetical 3rd antibody partner for further reinforcing the cocktail as pan-SARS-CoVs therapeutics. | Hangping Yao Yao Sun Yong-Qiang Deng Nan Wang Yongcong Tan Na-Na Zhang Xiao-Feng Li Chao Kong Yan-Peng Xuc Qi Chen Tian-Shu Cao Hui Zhao Xintian Yan Lei Cao Zhe Lv Dandan Zhu Rui Feng Nanping Wu Wenhai Zhang Yuhao Hu Keda Chen Rong-Rong Zhang Qingyu Lv Shihui Sun Yunhua Zhou Run Yan Guan Yang Xinglu Chanjuan Liu Xiangyun Lu Linfang Cheng Hongying Qiu Xing-Yao Huang Tianhao Weng Danrong Shi Weidong Jiang Junbin Shao Lei Wang Jie Zhang Tao Jiang Guojun Lang Cheng-Feng Qinc Lanjuan Li Xiangxi Wang | 2021 | Cell Research2021，31，1： | 5 |
| 13 | Dominant Synoptic Patterns and Their Relationships with PM2.5 Pollution in Winter over the Beijing–Tianjin–Hebei and Yangtze River Delta Regions in China显示文摘This paper concerns about the episodes of PM2.5 pollution that frequently occur in China in winter months.The severity of PM2.5 pollution is strongly dependent on the synoptic-scale atmospheric conditions.We combined PM2.5 concentration data and meteorological data with the Hybrid Single Particle Lagrangian Integrated Trajectory model(HYSPLIT4)to investigate the dominant synoptic patterns and their relationships with PM2.5 pollution over the Beijing–Tianjin–Hebei(BTH)and Yangtze River Delta(YRD)regions in the winters of 2014–17.The transport of PM2.5 from the BTH to YRD regions was examined by using cluster analysis and HYSPLIT4.It is found that the level of PM2.5 pollution over the BTH region was higher than that over the YRD region.The concentration of PM2.5 in the atmosphere was more closely related to meteorological factors over the BTH region.The episodes of PM2.5 pollution over the BTH region in winter were related to weather patterns such as the rear of a high-pressure system approaching the sea,a high-pressure field,a saddle pressure field,and the leading edge of a cold front.By contrast,PM2.5 pollution episodes in the YRD region in winter were mainly associated with the external transport of cold air,a high-pressure field,and a uniform pressure field.Cluster analysis shows that the trajectories of PM2.5 were significantly different under different weather patterns.PM2.5 would be transported from the BTH to the YRD within 48 h when the PM2.5 pollution episodes were associated with three different kinds of weather patterns:the rear of a highpressure system approaching the sea,the high-pressure field,and the leading edge of a cold front over the BTH region.This suggests a possible method to predict PM2.5 pollution episodes based on synoptic-scale patterns. | Yuzhi LIU Bing WANG Qingzhe ZHU Run LUO Chuqiao WU Rui JIA | 2019 | Journal of Meteorological Research2019，33，4： | 5 |
| 14 | Cloning the Structure Genes and Expression the N Gene of Porcine Epidemic Diarrhea Virus DX显示文摘The structure genes spike(S) ,nucleocapsid(N) ,membrane(M) ,small membrane(sM) of a porcine epidemic diarrhea virus(PEDV) strain DX isolated in Gansu province,North-west of China,were cloned,sequenced and compared with published sequences of PEDV strains. The nucleotide sequences encoding the entire S,sM,M and N genes open reading frame(ORF) of DX were 4 152,231,681 and 1 326 bases long respectively. There were transcription regulatory sequences(TRSs) upstream of the initiator ATG of the S,N and M genes. The amino acids sequences of S,M and N contained 30,3 and 7 potential asparagine(N) -linked glycosylation sites. Homologous analysis and phylogenetic trees showed that DX had the closest relationship with strains LJB/06,JS-2004-2Z and CH/HLJH/06 that were also isolated from China and indicated the prevalence of some PEDV isolates in China were widespread since the JS-2004-2Z strain originated from the south of the China,and LJB/06 and CH/HLJH/06 were isolated from northeast China. The N gene was cloned using two primers which contained Nco I and BamH I restriction enzyme sites and subcloned into expression vector pET30a. The recombinant plasmid was then transformed into E.coli Rossta. SDS-PAGE showed there was a protein of about 55kDa as expected and Western blot indicated the N protein had biological activity. | Jian-qiang LI Ji-xing LIU Xi LAN Jie CHENG Run WU Zhong-Zi LOU Xiang-ping YIN Xue-rui LI Bao-yu LI Bin YANG Zhi-yong LI | 2009 | Virologica Sinica2009，24，3： | 4 |
| 15 | Ultrafine monolayer Co-containing layered double hydroxide nanosheets for water oxidation显示文摘For many two-dimensional(2D)materials,low coordination edges and corner sites offer greatly enhanced catalytic performance compared to basal sites,motivating the search for new synthetic approaches towards ultrathin and ultrafine 2D nanomaterials with high specific surface areas.To date,the synthesis of catalysts that are both ultrathin(monolayer)and ultrafine(lateral size<10nm)has proven extremely challenging.Herein,using a facile ultrasonic exfoliation procedure,we describe the successful synthesis of ultrafine ZnCo-LDH nanosheets(denoted as ZnCo-UF)with a size^3.5 nm and thickness^0.5 nm.The single layer ZnCo-UF nanosheets possess an abundance of oxygen vacancies(Vo)and unsaturated coordination s让es,thereby affording outstanding electrocatalytic water oxidation performance.DFT calculations confirmed that Vo on the surface of ZnCo-UF enhanced H20 adsorption via increasing the electropositivity of the nanosheets. | Xiaodan Jia Xin Zhang Jiaqing Zhao Yufei Zhao Yunxuan Zhao Geoffrey I.N.Waterhouse Run Shi Li-Zhu Wu Chen-Ho Tung Tierui Zhang | 2019 | Journal of Energy Chemistry2019，28，7： | 3 |
| 16 | Multi-Objective Optimization for China's Power Carbon Emission Reduction by 2035显示文摘Low carbon transformation plays an important role in promoting the energy production and consumption revolution. Currently, the power sector of China still faces a series of challenges, such as the overcapacity of coal-fired power, the renewable energy consumption, the new constraints of carbon-emissions, and fragmented power planning. This study develops a multi-objective optimization model to predict the future trend of China power structure by 2035. The key factors such as network, power, load and storage are taken into account. Besides, the technical feasibility, economic rationality and social acceptable constraints are also fully considered. Through planning and optimization, the premise of low carbon transformation is to ensure the continuity of existing policies for removing inefficient assets, and the core is to develop and utilize non-fossil energy on a large scale. Specifically, the capacity of coal-fired power will be attained in the peak in 2025, and the factor will also transfer from main power supplier to main power and energy supplier. Before 2025, the clean replacement of incremental power installation will be completed. In 2035, 92% of new investment comes from non-fossil energy. The economy and competitiveness of wind power and PV(Photovoltaic) power generation are continuously increasing. By 2020, the coal-fired power and the wind power in eastern of China will be parity firstly. In 2025, the cost of PV and wind power will be the same. Furthermore, the evaluation dimension of modern power system with clean, low-carbon, safety and high efficiency are innovatively constructed, and the index system target of 2035 is quantitatively analyzed and prospected. | WU Jianjun TANG Guihua WANG Run SUN Yanwei | 2019 | Journal of Thermal Science2019，28，2： | 3 |
| 17 | Prion Protein Protects Cancer Cells against Endoplasmic Reticulum Stress Induced Apoptosis显示文摘Unfolded protein response(UPR) is an adaptive reaction for cells to reduce endoplasmic reticulum(ER) stress. In many types of cancers, such as lung cancer and pancreatic cancer, cancer cells may harness ER stress to facilitate their survival and growth. Prion protein(PrP) is a glycosylated cell surface protein that has been shown to be up-regulated in many cancer cells. Since PrP is a protein prone to misfolding, ER stress can result in under-glycosylated PrP, which in turn may activate ER stress. To assess whether ER stress leads to the production of under-glycosylated PrP and whether underglycosylated PrP may contribute to ER stress thus leading to cancer cell apoptosis, we treated different cancer cells with brefeldin A(BFA), thapsigargin(Thps), and tunicamycin(TM). We found that although BFA, Thps, and TM treatment activated UPR, only ATF4 was consistently activated by these reagents, but not other branches of ER stress. However, the canonical PERK-eIF2α-ATF4 did not account for the observed activation of ATF4 in lung cancer cells. In addition, BFA,but neither Thps nor TM, significantly stimulated the expression of cytosolic PrP. Finally, we found that the levels of PrP contributed to anti-apoptosis activity of BFA-induced cancer cell death. Thus, the pathway of BFA-induced persistent ER stress may be targeted for lung and pancreatic cancer treatment. | Zhenxing Gao Min Peng Liang Chen Xiaowen Yang Huan Li Run Shi Guiru Wu Lili Cai Qibin Song Chaoyang Li | 2019 | Virologica Sinica2019，34，2： | 2 |
| 18 | Soft tissue release combined with joint-sparing osteotomy for treatment of cavovarus foot deformity in older children: Analysis of 21 cases显示文摘BACKGROUND Cavovarus foot is a common form of foot deformity in children,which is clinically characterized by an abnormal increase of the longitudinal arch of the foot,and it can be simultaneously complicated with forefoot pronation and varus,rearfoot varus,Achilles tendon contracture,or cock-up toe deformity.Muscle force imbalance is the primary cause of such deformity.Many diseases can lead to muscle force imbalance,such as tethered cord syndrome,cerebral palsy,Charcot-Marie-Tooth disease,and trauma.At present,many surgical treatments are available for cavovarus foot.For older children,priority should be given to midfoot osteotomy and fusion.Since complications such as abnormal foot length,foot stiffness,and abnormal gait tend to develop postoperatively,it is important to preserve the joints and correct the deformity as much as possible.Adequate soft tissue release and muscle balance are the keys to correcting the deformity and avoiding its postoperative recurrence.AIM To assess the efficacy of soft tissue release combined with joint-sparing osteotomy in the treatment of cavovarus foot deformity in older children.METHODS The clinical data of 21 older children with cavovarus foot deformity(28 feet)who were treated surgically at the Ninth Department of Orthopedics of Jizhong Energy Xingtai Mining Group General Hospital from November 2014 to July 2017 were retrospectively analyzed.The patients ranged in age from 10 to 14 years old,with an average age of 12.46±1.20 years.Their main clinical manifestations were deformity,pain,and gait abnormality.The patients underwent magnetic resonance imaging of the lumbar spine,electromyographic examination,weightbearing anteroposterior and lateral X-rays of the feet,and the Coleman block test.Surgical procedures including metatarsal fascia release,Achilles tendon or medial gastrocnemius lengthening,'V'-shaped osteotomy on the dorsal side of the metatarsal base,opening medial cuneiform wedge osteotomy,closing cuboid osteotomy,anterior transfer of the posterior tibial tendon,peroneus longus-tobrevis transfer,and calcaneal sliding osteotomy to correct hindfoot varus deformity were performed.After surgery,long leg plaster casts were applied,the plaster casts were removed 6 wk later,Kirschner wires were removed,and functional exercise was initiated.The patients began weight-bearing walk 3 mo after surgery.Therapeutic effects were evaluated using the Wicart grading system,and Meary’s angles and Hibbs’angles were measured based on X-ray images obtained preoperatively and at last follow-up to assess their changes.RESULTS The patients were followed for 6 to 32 mo,with an average follow-up period of 17.68±6.290 mo.Bone healing at the osteotomy site was achieved at 3 mo in all cases.According to the Wicart grading system,very good results were achieved in 18 feet,good in 7,and fair in 3,with a very good/good rate of 89.3%.At last follow-up,mean Meary’s angle was 6.36°±1.810°,and mean Hibbs’angle was 160.21°±4.167°,both of which were significantly improved compared with preoperative values(24.11°±2.948°and 135.86°±5.345°,respectively;P<0.001 for both).No complications such as infection,skin necrosis,or bone nonunion occurred.CONCLUSION Soft tissue release combined with joint-sparing osteotomy has appreciated efficacy in the treatment of cavovarus foot deformity in older children. | Zhen-Yu Chen Zhan-Yong Wu Yue-Hui An Li-Fei Dong Jia He Run Chen | 2019 | World Journal of Clinical Cases2019，7，20： | 2 |
| 19 | Comparative study of MCe_(0.75)Zr_(0.25)O_(y)(M=Cu,Mn,Fe)catalysts for selective reduction of NO by CO:Activity and reaction pathways显示文摘Basic oxygen furnace steelmaking leads to the production of CO-rich off-gas.When CO and NO are combined in off-gas,selective catalytic reduction by CO(CO-SCR)effectively achieves the synergistic removal of both pollutants.In this paper,CuCe_(0.75)Zr_(0.25)O_(y),MnCe_(0.75)Zr_(0.25)O_(y),and FeCe_(0.75)Zr_(0.25)O_(y) catalysts are prepared and evaluated for their CO-SCR activity,and the results show that the reaction system needs to be anaerobic;thus,the CO-SCR reaction can be dominant.The T_(90) values of CuCe_(0.75)Zr_(0.25)O_(y) and FeCe_(0.75)Zr_(0.25)O_(y) are 200℃ and 223℃,respectively.The activities of these two catalysts are higher than that of MnCe_(0.75)Zr_(0.25)O_(y)(T_(90)=375℃).Linear nitrate and bridged bidentate nitrate are the main intermediate species involved in NO conversion on the catalyst surface,and bidentate CO_(3)^(2-)��coordination is the main intermediate species involved in CO conversion on the catalyst surface.CuCe_(0.75)Zr_(0.25)O_(y) has high lattice oxygen mobility and is more likely to react with NO and CO.In the presence of oxygen,most CO is oxidized by O_(2),which increases continuously to 100%,100%,and 98%for CuCe_(0.75)Zr_(0.25)O_(y),FeCe_(0.75)Zr_(0.25)O_(y),and MnCe_(0.75)Zr_(0.25)O_(y),respectively;additionally,CO is oxidized by O_(2),and the CO-SCR reaction cannot be carried out. | Junyao He Running Kang Xiaolin Wei Junqin Huang Feng Bin Kwun Nam Hui Kwan San Hui Dongyin Wu | 2021 | Carbon Resources Conversion2021，4，1： | 2 |
| 20 | The thermal physical formation of ZnO nanoparticles and their morphology显示文摘 | Xie Chang-sheng Xia Hui | 2000 | J Cryst Growth2000，217，： | 1 |
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