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| 1 | The HuangZaoSi Maize Genome Provides Insights into Genomic Variation and Improvement History of Maize显示文摘Maize is a globally important crop that was a classic model plant for genetic studies. Here, we report a 2.2 Gb draft genome sequence of an elite maize line, HuangZaoSi (HZS). Hybrids bred from HZS-improved lines (HILs) are planted in more than 60% of maize fields in China. Proteome clustering of six completed sequeneed maize genomes show that 638 proteins fall into 264 HZS-specific gene families with the majority of contributions from tandem duplication events. Resequencing and comparative analysis of 40 HZSrelated lines reveals the breeding history of HILs. More than 60% of identified selective sweeps were clustered in identity.by.descent conserved regions, and yield-related genes/QTLs were enriched in HZS characteristic selected regions. Furthermore, we dem on strated that HZS-specific family genes were not uniformly distributed in the genome but enriched in improvement/function.related genomic regions. This study provides an important and novel resource for maize genome research and expands our knowledge on the breadth of genomic variation and improvement history of maize. | Chunhui Li Wei Song Yingfeng Luo Shenghan Gao Ruyang Zhang Zi Shi Xiaqing Wang Ronghuan Wang Fengge Wang Jidong Wang Yanxin Zhao Aiguo Su Shuai Wang Xin Li Meijie Luo Shuaishuai Wang Yunxia Zhang Jianrong Ge Xinyu Tan Ye Yuan Xiaochun Bi Hang He Jianbing Yan Yuandong Wang Songnian Hu Jiuran Zhao | 2019 | Molecular Plant2019，12，3： | 15 |
| 2 | Neighborhood Effects and Regional Poverty Traps in Rural China显示文摘The present paper investigates how neighborhood effects are connected to chronic poverty.We examine a large sample of groups of households and find that neighborhood effects are significant in a majority of groups,especially in the poorest groups.People living in poor communities tend to suffer from poverty over time.It is of theoretical and empirical importance to explore how neighborhood effects are interrelated with chronic poverty and the channels through which this occurs.Unlike other econometric analyses,we establish a multilevel econometric model to show that:(i) it is difficult for an individual living in a neighborhood with a high proportion of agricultural labor,low education levels,and poor transport and telecommunication infrastructure to escape from poverty traps;(ii) neighborhood effects dominate in poor communities; and(iii) although poverty is affected by group-level factors,individual factors still play a dominant role in regards to escaping poverty when income surpasses a threshold level.Therefore,policy priority should be given to providing social protection and public services,especially in poor rural areas. | Yingfeng Fang Wei Zou | 2014 | China & World Economy2014，22，1： | 13 |
| 3 | Multiscale modeling of mechanical behavior and failure mechanism of 3D angle-interlock woven aluminum composites subjected to warp/weft directional tension loading显示文摘The mechanical behavior and progressive damage mechanism of novel aluminum matrix composites reinforced with 3D angle-interlock woven carbon fibers were investigated using a multiscale modeling approach.The mechanical properties and failure of yarns were evaluated using a microscale model under different loading scenarios.On this basis,a mesoscale model was developed to analyze the tensile behavior and failure mechanism of the composites.The interfacial decohesion,matrix damage,and failure of fibers and yarns were incorporated into the microscopic and mesoscopic models.The stress–strain curves and fracture modes from simulation show good agreement with the experimental curves and fracture morphology.Local interface and matrix damage initiate first under warp directional tension.Thereafter,interfacial failure,weft yarn cracking,and matrix failure occur successively.Axial fracture of warp yarn,which displays a quasi-ductile fracture characteristic,dominates the ultimate composites failure.Under weft directional tension,interfacial failure and warp yarn rupture occur at the early and middle stages.Matrix failure and weft yarn fracture emerge simultaneously at the final stage,leading to the cata-strophic failure of composites.The weft directional strength and fracture strain are lower than the warp directional ones because of the lower weft density and the more serious brittle fracture of weft yarns. | Zhenjun WANG Siyuan YANG Shiping SUN Yingfeng ZHANG Changchun CAI Bowen XIONG Wei YANG Zhifeng XU Huan YU | 2021 | Chinese Journal of Aeronautics2021，34，8： | 4 |
| 4 | Trajectory prediction of cyclist based on dynamic Bayesian network and long short-term memory model at unsignalized intersections显示文摘Cyclist trajectory prediction is of great significance for both active collision avoidance and path planning of intelligent vehicles.This paper presents a trajectory prediction method for the motion intention of cyclists in real traffic scenarios.This method is based on dynamic Bayesian network(DBN)and long short-term memory(LSTM).The motion intention of cyclists is hard to predict owing to potential large uncertainties.The DBN is used to infer the distribution of cyclists’intentions at intersections to improve the prediction time.The LSTM with encoder-decoder is used to predict the cyclists’trajectories to improve the accuracy of prediction.Therefore,the DBN and LSTM are adopted to guarantee prediction accuracy and improve the prediction time.The experiment results are presented to show the effectiveness of the predict strategies. | Hongbo GAO Hang SU Yingfeng CAI Renfei WU Zhengyuan HAO Yongneng XU Wei WU Jianqing WANG Zhijun LI Zhen KAN | 2021 | Science China(Information Sciences)2021，64，7： | 4 |
| 5 | Study on Surface Adsorption and Inhibition Behavior of Corrosion Inhibitors Contained in Copper Foil Rolling Oil显示文摘Adsorption and inhibition behavior of 2,5-bis(ethyldisulfanyl)-1,3,4-thiadiazole(DMTDA) and N-((6-methyl-1H-benzo[d][1,2,3]triazol-1-yl)methyl)-N-octyloctan-1-amine(EAMBA) as corrosion inhibitors contained in copper foil rolling oil have been investigated using gravimetric and electrochemical techniques. Meanwhile, scanning electron microscopy(SEM) and energy dispersive spectrometer(EDS) have been employed to observe the surface topography and analyze the components on copper foil. The results show that the rolling oil containing DMTDA and EAMBA can significantly decrease the dissolution rate and increase the inhibition efficiency of samples, especially in the case of best compounded rolling oil system. The SEM and EDS investigations also confirmed that the protection of the copper foil surface is achieved by strong adsorption of the molecules which can prevent copper from being corroded easily. Reactivity descriptors of the corrosion inhibitors have been calculated by the density functional theory(DFT) and the reactivity has been analyzed through the molecular orbital and Fukui indices. Active sites of inhibitor are mainly concentrated on the ring and the polar functional groups, and in the meanwhile, the distribution is helpful to form coordination and backbonding among molecules and then to form stable adsorption on the metal surface. And this work provides theoretical evidence for the selection of corrosion inhibitors contained in copper foil rolling oil. | Xiong Sang Sun Jianlin Jiang Wei Xu Yang Zeng Yingfeng Xia Lei | 2015 | China Petroleum Processing & Petrochemical Technology2015，17，1： | 3 |
| 6 | Properties of New Mullite-SiC Bricks for CDQ Shafts显示文摘Currently the service life of CDQ shafts in China is mainly restricted by the properties of the inclined flue bricks.In this work,based on the systematic analysis of the damage mechanism of inclined flue refractories,high performance mullite-SiC bricks were developed.The bricks were produced by corundum,andalusite,SiC and other high purity raw materials.Metal silicon and alumina ultra micropowder were added to form dispersion multi-phase structure,fortifying the matrix and improving the microstructure.The products have excellent properties such as low porosity,high density,good wear resistance,high refractoriness under load,and good thermal shock resistance.The products can replace the ordinary mullite-SiC bricks and obtain a good service life. | MA Shulong WEI Yingfeng WANG Zhifeng MA Fei XIA Wenbin ZHOU Xiaowei | 2017 | China's Refractories2017，26，1： | 2 |
| 7 | Confined compressive strength model of rock for drilling optimization显示文摘The confined compressive strength(CCS)plays a vital role in drilling optimization.On the basis of Jizba's experimental results,a new CCS model considering the effects of the porosity and nonlinear characteristics with increasing confining pressure has been developed.Because the confining pressure plays a fundamental role in determining the CCS of bottom-hole rock and because the theory of Terzaghi's effective stress principle is founded upon soil mechanics,which is not suitable for calculating the confining pressure in rock mechanics,the double effective stress theory,which treats the porosity as a weighting factor of the formation pore pressure,is adopted in this study.The new CCS model combined with the mechanical specific energy equation is employed to optimize the drilling parameters in two practical wells located in Sichuan basin,China,and the calculated results show that they can be used to identify the inefficient drilling situations of underbalanced drilling(UBD)and overbalanced drilling(OBD). | Xiangchao Shi Yingfeng Meng Gao Li a Jiaxue Li Zuwen Tao Shandong Wei | 2015 | Petroleum2015，1，1： | 1 |
| 8 | Expression of TGF-β1,Snail,E-cadherin and N-cadherin in Gastric Cancer and Its Significance显示文摘OBJECTIVE To investigate the expression of TGF-β1,Snail,E-cad-herin and N-cadherin in gastric cancer(GC),and to examine its relationship to malignant features of the tumors. METHODS The expression of TGF-β1,Snail,E-cadherin and N-cadherin proteins was detected in GC and adjacent tissues by immunohistochemical staining,and compared with the clinico-pathological data. RESULTS Positive rates of expression for TGF-β1,Snail,E-cadherin and N-cadherin were 63.5%,83.3%,37.5%and 44.8%in GC,and 28.8%, 41.3%,100%,11.3%in adjacent tissues,respectively.The expression of all four proteins showed a significant difference between the GCs and adjacent tissues(P<0.05).The positive rate of TGF-β1,Snail and N-cadherin,or the negative rate of E-cadherin expression was significantly related to the differentiated degree,histological type,invasion and metastasis of GC.In addition,the expression of N-cadherin was positively related to that of TGF-β1, but negatively related to that of E-cadherin.There was negative correlation between expression of E-cadherin and TGF-β1 and Snail in GC(P<0.05). CONCLUSION The over-expression of TGF-β1 and Snail and decreased expression of E-cadherin and the abnormal expression of N-cad-herin were involved in the process of invasion and metastasis of GC.The data showed that E-cadherin might switch to N-cadherin.TGF-β1 and Snail might play a fundamental role in the process. | Yingfeng Zhu Jifeng Wu Wei Ma Hong Zhang Daobin Wang | 2007 | Chinese Journal of Clinical Oncology2007，4，6： | 1 |
| 9 | Mechanism study and molecular design in controlled/“living” radical polymerization显示文摘This tutorial review summarizes recent progress in the research field of controlled/'living' radical polymerization (CLRP) from Soochow University.The present paper gives a broad overview of the mechanism study and molecular design in CLRP.The mechanism study in CLRP aided by microwave,initiated by γ-radiation at low temperature,mediated by iron,in reversible addition-fragmentation chain transfer (RAFT) polymerization and the mechanism transfer between different CLRP processes are reviewed and summarized.The molecular design in CLRP,especially in RAFT polymerization for mechanism study,and in achieving tailor-made functional polymers is studied and discussed in the later part. | TU YingFeng,CHENG ZhenPing,ZHANG ZhengBiao,ZHU Jian,ZHANG Wei,ZHOU NianChen,NI PeiHong & ZHU XiuLin College of Chemistry,Chemical Engineering and Materials Science,Soochow University,Suzhou 215123,China | 2010 | Science China Chemistry2010，53，8： | 1 |
| 10 | Effect of site-directed PEGylation of trichosanthin on its biological activity, immunogenicity, and pharmacokinetics显示文摘 | Qunxing An Yingfeng Lei Ning Jia Xianqing Zhang Yinlan Bai Jing Yi Rui Chen Aijun Xia Jing Yang Sanhua Wei Xiaodong Cheng Ailing Fan Shijie Mu Zhikai Xu | 2007 | Biomolecular Engineering2007，，6： | 1 |
| 11 | Mapping the antigenic determinants and reducing the immunogenicity of trichosanthin by site-directed mutagenesis显示文摘 | Qunxing An Sanhua Wei Shijie Mu Xianqing Zhang Yingfeng Lei Wei Zhang Ning Jia Xiaodong Cheng Ailing Fan Zhidong Li Zhikai Xu | 2006 | Journal of Biomedical Science2006，，5： | 1 |
| 12 | Computational Study of Ternary Devices: Stable, Low-Cost,and Efficient Planar Perovskite Solar Cells显示文摘Although perovskite solar cells with power conversion efficiencies(PCEs) more than 22% have been realized with expensive organic charge-transporting materials, their stability and high cost remain to be addressed. In this work, the perovskite configuration of MAPbX(MA = CH_3 NH_3,X = I_3, Br_3, or I_2Br) integrated with stable and low-cost Cu:Ni Oxhole-transporting material, ZnO electron-transporting material, and Al counter electrode was modeled as a planar PSC and studied theoretically. A solar cell simulation program(wx AMPS), which served as an update of the popular solar cell simulation tool(AMPS: Analysis of Microelectronic and Photonic Structures), was used. The study yielded a detailed understanding of the role of each component in the solar celland its effect on the photovoltaic parameters as a whole. The bandgap of active materials and operating temperature of the modeled solar cell were shown to influence the solar cell performance in a significant way. Further, the simulation results reveal a strong dependence of photovoltaic parameters on the thickness and defect density of the light-absorbing layers. Under moderate simulation conditions, the MAPb Br_3 and MAPbI _2 Br cells recorded the highest PCEs of 20.58 and 19.08%, respectively, while MAPbI_3 cell gave a value of 16.14%. | Sajid Sajid Ahmed Mourtada Elseman Jun Ji Shangyi Dou Dong Wei Hao Huang Peng Cui Wenkang Xi Lihua Chu Yingfeng Li Bing Jiang Meicheng Li | 2018 | Nano-Micro Letters2018，10，3： | 1 |
| 13 | Anisotropy of crack initiation strength and damage strength of coal reservoirs显示文摘The crack volume strain method and acoustic emission(AE)method are used to analyze the anisotropy of the crack initiation strength,damage strength,the failure mode and the AE characteristics of coal reservoir.The results show that coal reservoirs show obvious anisotropic characteristics in compressive strength,cracking initiation strength and damage strength.The compressive strength of coal reservoirs decreases with the increase of bedding angle,but the reservoirs with bedding angles of 450 and 900 differ little in compressive strength.The crack initiation strength and damage strength decrease first and then increase with the increase of bedding angle.The crack initiation strength and damage strength are the highest,at the bedding angle of 0°,moderate at the bedding angle of 90°,and lowest at the bedding angle of 45°.When the bedding angle is 0°,the failure of the coal reservoirs is mainly steady propagation of large-scale fractures.When the bedding angle is 45°,one type of failure is caused by steady propagation of small-scale fractures,and the other type of failure is due to a sudden instability of large-scale fractures.When the bedding angle is 90°,the failure is mainly demonstrated by a sudden-instability of small-scale fractures.Compared with the cumulative count method of the AE,the cumulative energy method is more suitable for determining crack initiation strength and damage strength of coal reservoirs. | HAO Xianjie WEI Yingnan YANG Ke SU Jian SUN Yingfeng ZHU Guangpei WANG Shaohua CHEN Haibo SUN Zhuowen | 2021 | Petroleum Exploration and Development2021，48，1： | 0 |
| 14 | Development of an Agrobacterium-mediated CRISPR/Cas9 system in pea(Pisum sativum L.)显示文摘Pea(Pisum sativum L.)is an annual cool-season legume crop.Owing to its role in sustainable agriculture as both a rotation and a cash crop,its global market is expanding and increased production is urgently needed.For both technical and regulatory reasons,neither conventional nor transgenic breeding techniques can keep pace with the demand for increased production.In answer to this challenge,CRISPR/Cas9 genome editing technology has been gaining traction in plant biology and crop breeding in recent years.However,there are currently no reports of the successful application of the CRISPR/Cas9 genome editing technology in pea.We developed a transient transformation system of hairy roots,mediated by Agrobacterium rhizogenes strain K599,to validate the efficiency of a CRISPR/Cas9 system.Further optimization resulted in an efficient vector,PsU6.3-tRNA-PsPDS3-en35S-PsCas9.We used this optimized CRISPR/Cas9 system to edit the pea phytoene desaturase(PsPDS)gene,causing albinism,by Agrobacterium-mediated genetic transformation.This is the first report of successful generation of gene-edited pea plants by this route. | Guan Li Rong Liu Rongfang Xu Rajeev KVarshney Hanfeng Ding Mengwei Li Xin Yan Shuxian Huang Juan Li Dong Wang Yishan Ji Chenyu Wang Junguang He Yingfeng Luo Shenghan Gao Pengcheng Wei Xuxiao Zong Tao Yang | 2023 | The Crop Journal2023，11，1： | 0 |
| 15 | Application and Hydration Resistance of SiC Refractories for Water-cooled Wall of Waste Incinerators显示文摘According to the dual needs of heat transfer and thermal insulation in incinerators,different parts of the incinerators are designed with refractories of different SiC contents.Water vapor is mainly concentrated in the zones of feeding,drying and combustion,and the main damage factors of SiC refractories include high temperature and hydration.The results of hydration resistance of typical SiC-containing refractories show that the higher the SiC content,the worse the hydration resistance.Si_(3)N_(4)-SiC refractories after oxidation treatment have good hydration corrosion resistance,which are appropriate for water-cooled wall of waste incinerators. | LUO Huaming CAI Binli YUAN Zhenqiang ZUO Genliang Zhang Jingzheng WANG Fengyu LI Jinyu WEI Yingfeng SUN Huochang ZHAN Huasheng | 2022 | China's Refractories2022，31，2： | 0 |
| 16 | The structure of Crimean-Congo hemorrhagic fever virus Gc is revealed;many more still need an answer显示文摘Crimean-Congo hemorrhagic fever virus(CCHFV)is regarded as one of the most deadly viruses,with mortality of up to 40%.Currently,no licensed vaccine with validated efficacy against CCHFV is available.CCHFV uses Gn and Gc glycoproteins to bind and penetrate the cell,like other bunyaviruses(Hulswit et al.,2021).Thus,the desired vaccines are needed,to elicit a potent neutralizing antibody(NAb)response to counteract this process. | Wei Ye Chuantao Ye Yongliang Hu Yangchao Dong Yingfeng Lei Fanglin Zhang | 2022 | Virologica Sinica2022，37，4： | 0 |
| 17 | RIPK3 promotes hantaviral replication by restricting JAK-STAT signaling without triggering necroptosis显示文摘Hantaan virus(HTNV)is a rodent-borne virus that causes hemorrhagic fever with renal syndrome(HFRS),resulting in a high mortality rate of 15%.Interferons(IFNs)play a critical role in the anti-hantaviral immune response,and IFN pretreatment efficiently restricts HTNV infection by triggering the expression of a series of IFNstimulated genes(ISGs)through the Janus kinase-signal transducer and activator of transcription 1(JAK-STAT)pathway.However,the tremendous amount of IFNs produced during late infection could not restrain HTNV replication,and the mechanism remains unclear.Here,we demonstrated that receptor-interacting protein kinase 3(RIPK3),a crucial molecule that mediates necroptosis,was activated by HTNV and contributed to hantavirus evasion of IFN responses by inhibiting STAT1 phosphorylation.RNA-seq analysis revealed the upregulation of multiple cell death-related genes after HTNV infection,with RIPK3 identified as a key modulator of viral replication.RIPK3 ablation significantly enhanced ISGs expression and restrained HTNV replication,without affecting the expression of pattern recognition receptors(PRRs)or the production of type I IFNs.Conversely,exogenously expressed RIPK3 compromised the host's antiviral response and facilitated HTNV replication.RIPK3^(-/-)mice also maintained a robust ability to clear HTNV with enhanced innate immune responses.Mechanistically,we found that RIPK3 could bind STAT1 and inhibit STAT1 phosphorylation dependent on the protein kinase domain(PKD)of RIPK3 but not its kinase activity.Overall,these observations demonstrated a noncanonical function of RIPK3 during viral infection and have elucidated a novel host innate immunity evasion strategy utilized by HTNV. | Yue Si Haijun Zhang Ziqing Zhou Xudong Zhu Yongheng Yang He Liu Liang Zhang Linfeng Cheng Kerong Wang Wei Ye Xin Lv Xijing Zhang Wugang Hou Gang Zhao Yingfeng Lei Fanglin Zhang Hongwei Ma | 2023 | Virologica Sinica2023，38，5： | 0 |
| 18 | Entropic pressure between fluctuating membranes in multilayer systems显示文摘Gaining insights into the fluctuation-induced entropic pressure between membranes that mediates cell adhesion and signal transduction is of great significance for understanding numerous physiological processes driven by intercellular communication.Although much effort has been directed toward investigating this entropic pressure,there still exists tremendous controversy regarding its quantitative nature,which is of primary interest in biophysics,since Freund challenged the Helfrich’s well-accepted results on the distance dependence.In this paper,we have investigated the entropic pressure between fluctuating membranes in multilayer systems under pressure and tension through theoretical analysis and Monte Carlo simulations.We find that the scaling relations associated with entropic pressure depend strongly on the magnitude of the external pressures in both bending rigidityand surface tension-dominated regimes.In particular,both theoretical and computational results consistently demonstrate that,in agreement with Helfrich,the entropic pressure p decays with inter-membrane separations c as p^c^(–3)for the tensionless multilayer systems confined by small external pressures.However,our results suggest that the entropic pressure law follows to be p^c^(–1)and p^c^(–3),respectively,in the limit of large and small thermal wavelengths for bending fluctuations of the membranes in a tensionindependent manner for the case of large external pressures. | Long Li Xiaohuan Wang Yingfeng Shao Wei Li Fan Song | 2018 | Science China(Physics,Mechanics & Astronomy)2018，61，12： | 0 |
| 19 | Multiple virus sorting based on aptamer-modified microspheres in a TSAW device显示文摘Due to the overlapping epidemiology and clinical manifestations of flaviviruses,differential diagnosis of these viral diseases is complicated,and the results are unreliable.There is perpetual demand for a simplified,sensitive,rapid and inexpensive assay with less cross-reactivity.The ability to sort distinct virus particles from a mixture of biological samples is crucial for improving the sensitivity of diagnoses.Therefore,we developed a sorting system for the subsequent differential diagnosis of dengue and tick-borne encephalitis in the early stage.We employed aptamer-modified polystyrene(PS)microspheres with different diameters to specifically capture dengue virus(DENV)and tick-borne encephalitis virus(TBEV),and utilized a traveling surface acoustic wave(TSAW)device to accomplish microsphere sorting according to particle size.The captured viruses were then characterized by laser scanning confocal microscopy(LSCM),field emission scanning electron microscopy(FE-SEM)and reverse transcription-polymerase chain reaction(RT‒PCR).The characterization results indicated that the acoustic sorting process was effective and damage-free for subsequent analysis.Furthermore,the strategy can be utilized for sample pretreatment in the differential diagnosis of viral diseases. | Xianglian Liu Xuan Chen Yangchao Dong Chuanyu Zhang Xiaoli Qu Yingfeng Lei Zhuangde Jiang Xueyong Wei | 2023 | Microsystems & Nanoengineering2023，9，3： | 0 |
| 20 | STING strengthens host anti-hantaviral immunity through an interferon-independent pathway显示文摘Hantaan virus(HTNV),the prototype virus of hantavirus,could escape innate immunity by restraining type I interferon(IFN)responses.It is largely unknown whether there existed other efficient anti-hantaviral tactics in host cells.Here,we demonstrate that the stimulator of interferon genes(STING)strengthens the host IFNindependent anti-hantaviral immunity.HTNV infection activates RIG-I through IRE1-XBP 1-mediated ER stress,which further facilitates the subcellular translocation and activation of STING.During this process,STING triggers cellular autophagy by interacting with Rab7A,thus restricting viral replication.To note,the anti-hantaviral effects of STING are independent of canonical IFN signaling.Additionally,neither application of the pharmacological antagonist nor the agonist targeting STING could improve the outcomes of nude mice post HTNV challenge in vivo.However,the administration of plasmids exogenously expressing the mutant C-terminal tail(ΔCTT)STING,which would not trigger the type I IFN responses,protected the nude mice from lethal HTNV infection.In summary,our research revealed a novel antiviral pathway through the RIG-I-STING-autophagy pathway,which offered novel therapeutic strategies against hantavirus infection. | Kerong Wang Jian Zhang Yongheng Yang Yue Si Ziqing Zhou Xudong Zhu Sushan Wu He Liu Hui Zhang Liang Zhang Linfeng Cheng Wei Ye Xin Lv Yingfeng Lei Xijing Zhang Shilin Cheng Lixin Shen Fanglin Zhang Hongwei Ma | 2023 | Virologica Sinica2023，38，4： | 0 |
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