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| 1 | Continuous wound infusion of local anaesthetic agents following colorectal surgery:Systematic review and meta-analysis显示文摘AIM:To provide a specifi c review and meta-analysis of the available evidence for continuous wound infusion of local anaesthetic agents following midline laparoto-my for major colorectal surgery. METHODS: Medline, Embase, trial registries, conference proceedings and article reference lists were searched to identify randomised, controlled trials of continuous wound infusion of local anaesthetic agents following colorectal surgery. The primary outcomes were opioid consumption, pain visual analogue scores (VASs), return to bowel function and length of hospital stay. Weighted mean difference were calculated for continuous outcomes. RESULTS: Five trials containing 542 laparotomy wounds were eligible for inclusion. There was a sig- nificant decrease in post-operative pain VAS at rest on day 3 (weighted mean difference: -0.43; 95% CI: -0.81 to -0.04; P = 0.03) but not on post-operative day 1 and 2. Local anaesthetic infusion was associated with a signifi cant reduction in pain VAS on movement on all three post-operative days (day 1 weighted mean difference: -1.14; 95% CI: -2.24 to -0.041; P = 0.04, day 2 weighted mean difference: -0.97, 95% CI: -1.91to -0.029; P = 0.04, day 3 weighted mean difference: -0.61; 95% CI: 1.01 to -0.20; P = 0.0038). Local an- aesthetic wound infusion was associated with a signifi - cant decrease in total opioid consumption (weighted mean difference: -40.13; 95% CI: -76.74 to -3.53; P = 0.03). There was no signifi cant decrease in length of stay (weighted mean difference: -20.87; 95% CI: -46.96 to 5.21; P = 0.12) or return of bowel function (weighted mean difference: -9.40; 95% CI: -33.98 to 15.17; P = 0.45). CONCLUSION: The results of this systematic re- view and meta-analysis suggest that local anaesthetic wound infusion following laparotomy for major color- ectal surgery is a promising technique but do not pro- vide conclusive evidence of benefi t. Further research is required including cost-effectiveness analysis. | Alan Karthikesalingam Stewart R Walsh Sheraz R Markar Umar Sadat Tjun Y Tang Charles M Malata | 2008 | World Journal of Gastroenterology2008,14,34: | 4 |
| 2 | Causes of encephalitis and differences in their clinical presentations in England: a multicentre, population-based prospective study显示文摘 | Julia Granerod Helen E Ambrose Nicholas WS Davies Jonathan P Clewley Amanda L Walsh Dilys Morgan Richard Cunningham Mark Zuckerman Ken J Mutton Tom Solomon Katherine N Ward Michael PT Lunn Sarosh R Irani Angela Vincent David WG Brown Natasha S Crowcroft | 2010 | The Lancet Infectious Diseases2010,,12: | 2 |
| 3 | Chelex 100 as a medium for simple extraction of DNA for PCR-based typing from forensic material 显示文摘 | Walsh P S Metzger D A Higuchi R | 1991 | Bio Techniques1991,10,: | 2 |
| 4 | Chelex-100 as a medium for simple extraction of DNA for PCR-based typing from forensic material显示文摘 | Walsh PS Metzger DA Higuchi R | 1991 | Biotechniques1991,10,4: | 2 |
| 5 | Robotic surgery of the pancreas显示文摘Pancreatic surgery is one of the most challenging and complex fields in general surgery.While minimally invasive surgery has become the standard of care for many intra-abdominal pathologies the overwhelming majority of pancreatic surgery is performed in an open fashion.This is attributed to the retroperitoneal location of the pancreas,its intimate relationship to major vasculature and the complexity of reconstruction in the case of pancreatoduodenectomy.Herein,we describe the application of robotic technology to minimally invasive pancreatic surgery.The unique capabilities of the robotic platform have made the minimally invasive approach feasible and safe with equivalent if not better outcomes(e.g.,decreased length of stay,less surgical site infections)to conventional open surgery.However,it is unclear whether the robotic approach is truly superior to traditional laparoscopy;this is a key point given the substantial costs associated with procuring and maintaining robotic capabilities. | Daniel Joyce Gareth Morris-Stiff Gavin A Falk Kevin El-Hayek Sricharan Chalikonda R Matthew Walsh | 2014 | World Journal of Gastroenterology2014,20,40: | 2 |
| 6 | Association of glycolytic enzymes with the cytoskeleton显示文摘 | Knull H R Walsh J L | 1992 | Curt Top Cell Regul1992,33,: | 1 |
| 7 | Air pollution exposure-DNA adduct dosimetry in humans and rodents : evidence for non-linearity at high doses显示文摘 | LEWTAS J WALSH D WILLIAMS R | 1997 | Muta Res1997,378,: | 1 |
| 8 | Surgery, of Rathke cleft cysts: fechical considerations and oulcomcs 显示文摘 | Benveniste R J King WA Walsh J | 2004 | J Neurosurg2004,101,4: | 1 |
| 9 | Limiting Conditions for Jet Formation in High Velocity Collisions 显示文摘 | Shreffler R G Willig F J | 1953 | J Appl Phys1953,24,: | 1 |
| 10 | Detection of Potato mop top virus and Tobacco rattle virus using a multiplex real- time fluorescent reverse transcription polymerase chain reaction assay显示文摘 | Mumford R A Walsh K Barker I | 2000 | Phytopathology2000,90,5: | 1 |
| 11 | Sequence and structure of the Drosophila melanogaster ovarian tumor gene and generation of an antibody specific for the ovarian tumor protein显示文摘 | Steinhauer W R Walsh R C Kalfayan L J | 1989 | Mol Cell Biol1989,9,12: | 1 |
| 12 | Controlled release of platelet-derived growth factor using ethylene vinyl acetate copolymer(EVAc)coated on stainless-steel wires显示文摘 | Walsh W R Kim H D Jong Y S | 1995 | Biomaterials1995,16,17: | 1 |
| 13 | Chelex 100 as a medium for simple extraction of DNA for PCR based typing from forensic material显示文摘 | Walsh P S Metzger D A Higuchi R | 1991 | Bio Techniques1991,10,: | 1 |
| 14 | The effect of subclinical ketosis in early lactation on reproductive performance of postparturn dairy cows显示文摘 | WALSH R B WALTON J S KELTON D F | 2007 | J Dairy Sci2007,90,6: | 1 |
| 15 | Organizational memory 显示文摘 | Walsh J P Ungson G R | 1991 | Academy of Management Review1991,16,1: | 1 |
| 16 | Drosophila suzukii (Diptera:Drosophilidae):invasive pest of ripening soft fruit expanding its geographic range and damage potential显示文摘 | Walsh D B Bolda M P Goodhue R E | | 0,,: | 1 |
| 17 | Cardioprotection by adiponectin显示文摘 | Ouchi N Shibata R Walsh K | | 0,,05: | 1 |
| 18 | The influence of the geo-logical setting on the morphogenetic evolution of the TremitiArchipelago (Apulia, Southeastern Italy) 显示文摘 | Andriani G F Walsh N Pagliarulo R | 2005 | Natural Hazardsand Earth System Science2005,5,1: | 1 |
| 19 | Over-connected?A qualitative exploration of the relationship between Australian youth and their mobile phones显示文摘 | WALSH S P WHITE K M YOUNG R M | 2008 | J Adolesc2008,31,1: | 1 |
| 20 | Continued excellent results with the minigastric bypass : six-year study in 2,410 patients 显示文摘 | Rutledge R Walsh TR | 2005 | Obes Surg2005,15,9: | 1 |