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| 1 | 切割球囊成形术与经皮腔内β-射线放射疗法联合治疗冠状动脉支架内再狭窄显示文摘目的 观察切割球囊成形术 (CBA)与经皮冠状动脉 (冠脉 )内 β 射线放射疗法 (β 放疗 )联合治疗支架内再狭窄 (ISR)的疗效及其安全性。方法 冠脉内支架置入术后ISR >70 %的患者2 95例 ,男性 2 0 5例 ,女性 90例 ,平均年龄 (5 9 76± 10 83)岁 ,其中 112例均行CBA联合 β 放疗作为β 放疗组 (n =112 ) ,183例单独采用CBA(89例 )或普通球囊扩张成形术 (94例 )为对照组 (n =183)。弥漫性长病变ISR者回撤 β 放疗导管分段照射。所有患者术前、术后即刻及术后随访期行冠脉造影 ,随访靶血管血运重建 (TVR)和主要不良心血管事件 (MACE)发生率。结果 两组患者的术前及术后即刻冠脉造影结果差异无显著性。随访期 (6 3± 1 6 )月 β 放疗组的最小管腔直径大于对照组 ,管腔直径狭窄百分比小于对照组 ,P <0 0 5。β 放疗组与对照组的心绞痛、心肌梗死及病死率相似(心绞痛为 10 %比 17% ,心肌梗死为 1%比 2 % ,病死率为 0 %比 2 % ) ,但 β 放疗组的TVR和MACE明显低于对照组 (TVR为 5 %比 16 % ,MACE为 11%比 2 1% ,P <0 0 5 )。β 放疗组 2 8例 (2 5 % )弥漫性长病变ISR ,分段照射后随访TVR和MACE无增加。结论 冠脉内 β 放疗和CBA相结合治疗ISR安全、有效 ,TVR和MACE明显降低。采用回撤 β 放疗导管? | 樊冰 葛均波 von Birgelen C 钱菊英 王齐兵 葛雷 陈灏珠 Erbel R | 2004 | 中华心血管病杂志2004，32，5： | 12 |
| 2 | Portable lensless wide-field microscopy imaging platform based on digital inline holography and multi-frame pixel super-resolution显示文摘In this paper,an irregular displacement-based lensless wide-field microscopy imaging platform is presented by combining digital in-line holography and computational pixel super-resolution using multi-frame processing.The samples are illuminated by a nearly coherent illumination system,where the hologram shadows are projected into a complementary metal-oxide semiconductor-based imaging sensor.To increase the resolution,a multi-frame pixel resolution approach is employed to produce a single holographic image from multiple frame observations of the scene,with small planar displacements.Displacements are resolved by a hybrid approach:(i)alignment of the LR images by a fast feature-based registration method,and(ii)fine adjustment of the sub-pixel information using a continuous optimization approach designed to find the global optimum solution.Numerical method for phase-retrieval is applied to decode the signal and reconstruct the morphological details of the analyzed sample.The presented approach was evaluated with various biological samples including sperm and platelets,whose dimensions are in the order of a few microns.The obtained results demonstrate a spatial resolution of 1.55 μm on a field-of-view of<30 mm^(2). | Antonio C Sobieranski Fatih Inci H Cumhur Tekin Mehmet Yuksekkaya Eros Comunello Daniel Cobra Aldo von Wangenheim Utkan Demirci | 2015 | Light(Science & Applications)2015，4，1： | 7 |
| 3 | Factors associated with long-term survival after liver transplantation:A retrospective cohort study显示文摘AIM To identify predictive factors associated with long-term patient and graft survival(> 15 years) in liver transplant recipients.METHODS Medical charts of all de novo adult liver transplant recipients(n = 140) who were transplanted in Hamburg between 1997 and 1999 were retrospectively reviewed.In total,155 transplantations were identified in this time period(15 re-transplantations).Twenty-six orthotopic liver transplant(OLT) recipients were early lost to followup due to moving to other places within 1 year after transplantation.All remaining 114 patients were included in the analysis.The following recipient factors were analysed:Age,sex,underlying liver disease,pre-OLT body mass index(BMI),and levels of alanine aminotransferase(ALT),bilirubin,creatinine and gammaglutamyltransferase(gamma-GT),as well as warm and cold ischemia times.Furthermore,the following donor factors were assessed:Age,BMI,cold ischemia time and warm ischemia time.All surviving patients were followed until December 2014.We divided patients into groups according to their underlying diagnosis:(1) hepatocellularcarcinoma(n = 5,4%);(2) alcohol toxic liver disease(n = 25,22.0%);(3) primary sclerosing cholangitis(n = 6,5%);(4) autoimmune liver diseases(n = 7,6%);(5) hepatitis C virus cirrhosis(n = 15,13%);(6) hepatitis B virus cirrhosis(n = 21,19%);and(7) other(n = 35,31%).The group 'other' included rare diagnoses,such as acute liver failure,unknown liver failure,stenosis and thrombosis of the arteria hepatica,polycystic liver disease,Morbus Osler and Caroli disease.RESULTS The majority of patients were male(n = 70,61%).Age and BMI at the time point of transplantation ranged from 16 years to 69 years(median:53 years) and from 15 kg/m^2 to 33 kg/m^2(median:24),respectively.Sixty-six OLT recipients(58%) experienced a follow-up of 15 years after transplantation.Recipient's age(P = 0.009) and BMI(P = 0.029) were identified as risk factors for death by χ~2-test.Kaplan-Meier analysis confirmed BMI or age above the median as predictors of decreased long-term survival(P = 0.008 and P = 0.020).Hepatitis B as underlying disease showed a trend for improved long-term survival(P = 0.049,χ~2-test,P = 0.055;Kaplan-Meier analysis,Log rank).Pre-transplant bilirubin,creatinine,ALT and gamma-GT levels were not associated with survival in these patients of the pre-era of the model of end stage liver disease.CONCLUSION The recipients' age and BMI were predictors of longterm survival after OLT,as well as hepatitis B as underlying disease.In contrast,donors' age and BMI were not associated with decreased survival.These findings indicate that recipient factors especially have a high impact on long-term outcome after liver transplantation. | Sven Pischke Marie C Lege Moritz von Wulffen Antonio Galante Benjamin Otto Malte H Wehmeyer Uta Herden Lutz Fischer Bjorn Nashan Ansgar W Lohse Martina Sterneck | 2017 | World Journal of Hepatology2017，9，8： | 5 |
| 4 | 当前围手术期处理模式:北欧五国结直肠外科医生调查显示文摘 | Kristoffer Lassen Pascal Hannemann Olle Ljungqvist Ken Fearon Cornelis H C Dejong Maarten F von Meyenfeldt Jonatan Hausel Jonas Nygren Jens Andersen Arthur Revhaug 王东 | 2005 | 英国医学杂志中文版2005，8，6： | 3 |
| 5 | 采用不同导管和技术的去肾交感神经术治疗单纯收缩期高血压:一项随机试验结果显示文摘目前认为单纯收缩期高血压(isolated systolic hypertension,ISH)患者经去肾交感神经术(renal sympathetic denervation,RDN)后血压降低。此结论绝大多数来自单极射频导管消融的研究。但采用新的RDN的数据有限。研究者采用比较3种不同RDN方法的RADIOSOUND-HTN(采用不同RDN导管与技术治疗顽固性高血压患者的三臂随机试验)数据,探讨ISH与RDN反应的可能交互作用。 | Fengler K Rommel KP Lapusca R Blazek S Besler C Hartung P von Roeder M Kresoja KP Desch S Thiele H Lurz P 赵狄 练桂丽 | 2019 | 中华高血压杂志2019，27，7： | 2 |
| 6 | Analysis of orthopedic surgical procedures in children with cerebral palsy显示文摘BACKGROUND Orthopedic surgery in children with cerebral palsy(CP)aims to improve function and prevent deformities.Each child’s condition in CP is unique and many covariables influence surgical decision-making including a patient's age and their functional level.Little is known about the frequency of different types of orthopedic surgery in children with CP who have varied functional levels,particularly in countries from Latin America.AIM To assess the type of orthopedic surgical procedures in relation to age and gross motor function in children with CP.METHODS This retrospective study included all children with CP(n=245)treated with elective orthopedic surgery at a Uruguayan university hospital between October 2010 and May 2016 identified from a surgical database.Eighteen children(7%)were lost to follow-up due to missing medical charts.Demographics,gross motor function classification(GMFCS),and orthopedic surgeries were obtained from the medical records of 227 children.Chi-squared tests and analysis of variance were used to assess the frequency of surgery,accounting for GMFCS levels.Mean age for soft tissue vs bone surgery was compared with the independent samples t-test.RESULTS A total of 711 surgical procedures were performed between 1998 and 2016.On average,children had 3.1 surgical procedures and the mean age at first surgery was 8.0 years.There were no significant differences in age at first surgery among GMFCS levels(P=0.47).The most common procedures were lower leg soft tissue surgery(n=189,27%),hip tenotomy(n=135,19%),and hamstring tenotomy(n=104,14%).For children with GMFCS level Ⅰ,the mean number of surgeries per child[1.8(range 1-9)]differed significantly at P<0.05 in children with GMFCS levels Ⅱ[3.2(1-12)],Ⅲ[3.2(1-8)],Ⅳ[3.3(1-13)],and Ⅴ[3.6(1-11)].Within Ⅱ,Ⅲ,Ⅳ,and Ⅴ,there was no significant difference in mean number of surgeries per child when comparing across the groups.The proportion of soft tissue surgery vs bone surgery was higher in GMFCS levels Ⅰ-Ⅲ(80%-85%)compared to levels IV(68%)and V(55%)(P<0.05).CONCLUSION The frequency of surgical procedures per child did not increase with higher GMFCS level after level Ⅰ.However,the proportion of bone surgery was higher in GMFCS levels Ⅳ-Ⅴ compared to Ⅰ-Ⅲ. | Ignacio Rehbein Viviana Teske Ignacio Pagano Alejandro Cúneo María Elena Pérez Johan von Heideken | 2020 | World Journal of Orthopedics2020，11，4： | 2 |
| 7 | Gut microbiota disturbance during antibiotic therapy: a multi-omic approach显示文摘 | Ana Elena Pérez-Cobas María José Gosalbes Anette Friedrichs Henrik Knecht Alejandro Artacho Kathleen Eismann Wolfgang Otto David Rojo Rafael Bargiela Martin von Bergen Sven C Neulinger Carolin D?umer Femke-Anouska Heinsen Amparo Latorre Coral Barbas Jana | 2013 | Gut2013，，11： | 2 |
| 8 | Preservation of mitochondrial structure and function after Bid or Bax mediated cytochrome c release显示文摘 | von Ahnsen O Renkin C Perkens G | 2001 | J Cell Biol2001，150，5： | 1 |
| 9 | Barley glutamyl tRNAGIu reductase:mutations affecting haem inhibition and enzyme activity显示文摘 | VOTHKNECHT U C KANNANGARA C G VON WETTSTEIN D | 1998 | Phytochemistry1998，47，： | 1 |
| 10 | Isolation and characterization of the falty acid-binding protein from human heart显示文摘 | Unterberg C Heidl G Von Bassewitz DB | 1986 | J Lipid Res1986，27，12： | 1 |
| 11 | Cardiac tamponade in the 'new device' era:evaluation of 6999 consecutive percutaneous coronary interventions显示文摘 | Kopistansky C Cohen M | 2000 | Am Heart J2000，140，2： | 1 |
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| 13 | Space-Based Space Surveillance with the Space-Based Visible 显示文摘 | Gaposchkin E M Von Braun C | 2000 | Journal of Guidance Control and Dynamics2000，23，1： | 1 |
| 14 | On the origin of the human influenza virus subtypes H2N2 and H3N2显示文摘 | Scholtissek C Rohde W Von Hoyningen V | 1978 | Virology1978，87，1： | 1 |
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| 18 | Paclitaxel-induced apoptosis in BJAB cells proceeds via a death receptor-independent,caspases-3 /-8-driven mitochondrial amplification loop显示文摘 | von Haefen C Wieder T Essmann F | 2003 | Oncogene2003，22，15： | 1 |
| 19 | The receptive endometrium is characterized by apoptosis in the glands显示文摘 | Von Rango U Classen-Linke I Kruche C A | 1998 | Hum Reprod1998，13，11： | 1 |
| 20 | Dispatch of hydroelectric generating units using multi-objective evolutionary algorithms显示文摘 | Villasanti C M Von Lucken C Baran B | 2004 | IEEE Trans on Power Systems2004，19，8： | 1 |
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