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| 1 | Bevacizumab in the pre-operative treatment of locally advanced rectal cancer: A systematic review显示文摘Despite advances in the management of patients with locally advanced,non-metastatic rectal adenocarcinoma(LARC),prognosis remains largely unsatisfactory due to a high rate of distant relapse.In fact,currently available neoadjuvant protocols,represented by fluoropyrimidine-based chemo-radiotherapy(CT-RT)or short-course RT,together with improved surgical techniques,have largely reduced the risk of local relapse,with limited impact on distant recurrence.Available results of phaseⅢtrials with additional cytotoxic agents combined with standard CT-RT are disappointing,as no significant reduction in the risk of recurrence has been demonstrated.In order to improve the control of micrometastatic disease,integrating targeted agents into neoadjuvant treatment protocols thus offers a rational approach.In particular,the antiangiogenic agent bevacizumab has demonstrated synergistic activity with both CT and RT in pre-clinical and clinical models,and thusmay represent a suitable companion in the neoadjuvant treatment of LARC.Preliminary results of phase?Ⅰ-Ⅱclinical studies are promising and suggest potential clinical parameters and molecular predictive biomarkers useful for patient selection:treatment personalization is indeed the key in order to maximize the benefit while reducing the risk of more complex neoadjuvant treatment schedules. | Lorenzo Fornaro Chiara Caparello Caterina Vivaldi Virginia Rotella Gianna Musettini Alfredo Falcone Editta Baldini Gianluca Masi | 2014 | World Journal of Gastroenterology2014，20，20： | 5 |
| 2 | Retinoic acid rece tor beta re-expressi-on and growth inhibition in thyroid carcinoma cell lines after 5-aza-2'-deoxycytidine treatment显示文摘 | Miasaki FY Vivaldi A Ciampi R | 2008 | J Endocrinol Invest2008，31，8： | 1 |
| 3 | Re-differentiation of thyroid carcinoma cell lines treated with 5-Aza-2'-deoxycytidine and retinoic acid显示文摘 | Vivaldi A Miasaki FY Ciampi R | | 0，，： | 1 |
| 4 | Endoscopic therapy for esophageal perforation or anastomotic leak with a self-expandable metallic stent显示文摘 | Jessica M. Leers Carlo Vivaldi Hartmut Sch?fer Marc Bludau Jan Brabender Georg Lurje Till Herbold Arnulf H. H?lscher Ralf Metzger | 2009 | Surgical Endoscopy2009，，10： | 1 |
| 5 | Severe bleeding due to acquired hypoprothrombinemia-lupus anticoagulant syndrome: case report and review of literature 显示文摘 | Vivaldi P Rossetti G Galli M | 1997 | Haematologica1997，82，： | 1 |
| 6 | Salvage of ischaemic myocardium by reperfusion: importance of collateral blood flow and myocardial oxygen demand during occlusion 显示文摘 | Przyklenk K Vivaldi M T Schoen F J | 1986 | Cardiovasc Res1986，20，6： | 1 |
| 7 | Modelocking in coupled map lattices显示文摘 | Carretero-Gonzalez R Arrowsmith D K Vivaldi F | 1997 | Physica D1997，103，： | 1 |
| 8 | One-dimensional classical many-body system having a normal thermal conductivity显示文摘 | CASATI G FORD J VIVALDI F | 1984 | Phys Rev Lett1984，52，： | 1 |
| 9 | All-trans-retinoic acid treatment inhibits the growth of retinoic acid receptor beta messenger ribonucleic acid expressing thyroid cancer cell lines but does not reinduce the expression of thyroid-specific genes显示文摘 | Vivaldi A Agate L | 2005 | Clin Endocrinol Metab2005，90，4： | 1 |
| 10 | Endoscopic therapy for esoph- ageal perforation or anastomotic leak with a self-expandable metallic stent显示文摘 | Leers JM Vivaldi C Schafer I-I | 2009 | Surg Endosc2009，23，10： | 1 |
| 11 | The efficacy of a fluoride varnish in reducing enamel demineralization adjacent to orthodontic brackets: An in vitro study显示文摘 | Demito CF Vivaldi Rodrigues G Ramos AL | 2004 | Orthod Craniofac Res2004，7，4： | 1 |
| 12 | Simian virus 40-like DNA sequences in human papillary thyroid carcinomas 显示文摘 | Pacini F Vivaldi A Santoro M | 1998 | Oncogene1998，16，5： | 1 |
| 13 | One dimensional classical many-body system having a normal thermal conductivity显示文摘 | Castai G Ford J Vivaldi F | 1984 | Physi- cal Review Letters1984，52，21： | 1 |
| 14 | Expression analysis of facilitative glucose transporters (GLUTs) in human thyroid carcinoma cell lines and primary tumors显示文摘 | Ciampi R Vivaldi A Romei C | 2008 | Mol Cell Endocrinol2008，291，12： | 1 |
| 15 | Simian virus 40-like sequencesfrom early and late regions in human thyroid tumors of different his-totypes 显示文摘 | Vivaldi A Pacini F Martini | 2003 | The Journal of Clinical Endocrinology & Metabolism2003，88，2： | 1 |
| 16 | Endoscopic therapy {or esophageal per{oration or anastomotic leak with a sel{-ex- pandable metallic stent 显示文摘 | Leers JM Vivaldi C Schiller H | 2009 | Surg Endosc2009，23，10： | 1 |
| 17 | Celecoxib,a cyclooxygenase-2 inhibitor, potentiates the chemotherapic effect of vinorelbine inthe medullary thyroid cancer TT cell line 显示文摘 | A Vivaldi R Ciampi A Tacito | 2012 | Mol Cell Endocri-nol2012，355，1： | 1 |
| 18 | Reliability of Optic Nerve Ultrasound for the Evaluation of Patients with Spontaneous Intracranial Hemorrhage显示文摘 | Riccardo Moretti Barbara Pizzi Fabrizio Cassini Nicoletta Vivaldi | 2009 | Neurocritical Care2009，，3： | 1 |
| 19 | Clinical significance of serum mesothelin in patients with mesothelioma and lung cancer显示文摘 | Cristaudo A Foddis R Vivaldi A | 2007 | Clin Cancer Res2007，13，17： | 1 |
| 20 | Reliability of Optic Nerve Ultrasound for the Evaluation of Patients with Spontaneous Intracranial Hemorrhage显示文摘 | Riccardo Moretti Barbara Pizzi Fabrizio Cassini Nicoletta Vivaldi | 2009 | Neurocritical Care2009，，3： | 1 |
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