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| 1 | Report of an international workshop to standardize baseline evaluation and response criteria for primary CNS lymphoma.显示文摘 | Abrey LE Batchelor TT Ferreri A J Gospodarowicz M Pulczynski EJ Zucca E Smith JR Korfel A Soussain C DeAngelis LM Neuwelt EA O′Neill BP Thiel E Shenkier T Graus F van den Bent M Seymour JF Poortmans P Armitage JO Cavalli F | 2005 | 中国神经肿瘤杂志2005，3，3： | 53 |
| 2 | 欧洲呼吸学会和欧洲胸外科医师学会恶性胸膜间皮瘤诊疗指南显示文摘恶性胸膜间皮瘤(malignant pleural mesothelioma,MPM)是一种罕见肿瘤,但发病率正逐渐上升,且预后较差。2008年,欧洲呼吸学会(European Respiratory Society,ERS)和欧洲胸外科医师学会(European Society of Tho-racic Surgeons,ESTS)特别工作组召集各方专家计划制定MPM诊治经验及更新指南。为了使MPM得到及时准确的诊断,专家推荐对患者实施胸腔镜检查,有手术禁忌和胸腔粘连的病例除外。约10%的病例采用标准染色方法无法获得满意的结果。因此我们推荐在胸膜活检的基础上,采用特异性免疫组化标志物。由于目前缺乏一个统一的、切实有效的分期系统,我们推荐应用最新的TNM分期,并且提出三个阶段的治疗前评估。在MPM的治疗中,患者的体力状态评分和组织亚型是目前唯一的、具有重要临床价值的预后因素。在临床试验中,应对其它潜在因素进行初步探讨并予以报道。MPM对化疗高度耐受,仅有少数患者可接受根治性手术。本文对新的治疗方法和策略进行了综述。目前由于最佳综合治疗的资料有限,适合采用多种方案联合治疗策略的患者应被纳入专业机构的前瞻性试验中。 | A. Scherpereel P. Astoul P. Baas T. Berghmans H. Clayson P. de Vuyst H. Dienemann F. Galateau-Salle C. Hennequin G. Hillerdal C. Le Pe'choux L. Mutti J-C. Pairon R. Stahel P. van Houtte J. van Meerbeeck D. Waller W. Weder 宋作庆 徐萧洪 | 2010 | 中国肺癌杂志2010，，10： | 56 |
| 3 | Lower Bifidobacteria counts in both duodenal mucosa-associated and fecal microbiota in irritable bowel syndrome patients显示文摘AIM: To determine the composition of both fecal and duodenal mucosa-associated microbiota in irritable bowel syndrome (IBS) patients and healthy subjects using molecular-based techniques. METHODS: Fecal and duodenal mucosa brush samples were obtained from 41 IBS patients and 26 healthy subjects. Fecal samples were analyzed for the composition of the total microbiota using fluorescent in situ hybridization (FISH) and both fecal and duodenal brush samples were analyzed for the composition of bif idobacteria using real-time polymerase chain reaction. RESULTS: The FISH analysis of fecal samples revealed a 2-fold decrease in the level of bifidobacteria (4.2 ± 1.3 vs 8.3 ± 1.9, P < 0.01) in IBS patients compared to healthy subjects, whereas no major differences in other bacterial groups were observed. At the species level, Bifidobacterium catenulatum levels were significantly lower (6 ± 0.6 vs 19 ± 2.5, P < 0.001) in the IBS patients in both fecal and duodenal brush samples than in healthy subjects.CONCLUSION: Decreased bifidobacteria levels in both fecal and duodenal brush samples of IBS patients compared to healthy subjects indicate a role for microbiotic composition in IBS pathophysiology. | Angèle PM Kerckhoffs Melvin Samsom Michel E van der Rest Joris de Vogel Jan Knol Kaouther Ben-Amor Louis MA Akkermans | 2009 | World Journal of Gastroenterology2009，15，23： | 33 |
| 4 | 世界胃肠病学组织全球指南——发展中国家幽门螺杆菌感染显示文摘世界上有一半人口感染幽门螺杆菌(H.pylori),其感染率因地理位置、种族、年龄和社会经济状况不同而存在很大差异.在发展中国家较高.发达国家较低。但总体而言,近年世界许多地区的H.pylori感染率均呈下降趋势。 | Hunt RH Xiao SD Megraud F Leon-Barua R Bazzoli F van der Merwe S Vaz Coelho LG Fock M Fedail S Cohen H Malfertheiner P Vakil N Hamid S Goh KL Wong BCY Krabshuis J Le Mair A 杜颖 戴宁 | 2011 | 胃肠病学2011，16，7： | 27 |
| 5 | A Single Active Trehalose-6-P Synthase (TPS) and a Family of Putative Regulatory TPS-Like Proteins in Arabidopsis显示文摘更高的植物典型地不在大数量生产 trehalose,但是他们的染色体序列揭示通常认为的 trehalose 新陈代谢酶的大家庭。在植物生长和开发的一个重要规章的角色也为新陈代谢的中间的 trehalose-6-P (T6P ) 正在出现。这里,我们在场 Arabidopsis trehalose 新陈代谢上的更改和为进一步详细的分析的一个资源。另外,我们提供 Arabidopsis 靠着可能在活跃地种纸巾完成特定的规章的功能的催化地不活跃的象 TPS 一样蛋白质的一个家庭编码单个 trehalose-6-P synthase (TPS ) 的证据。 | Lies Vandesteene Matthew Ramon Katrien Le Roy Patrick Van Dijck Filip Rolland | 2010 | Molecular Plant2010，3，2： | 22 |
| 6 | 振动压路机用于不同土壤地面的平顺性评价显示文摘实际工况中振动压路机车轮会在各种土壤地面上作业和行驶,为了评价振动式压路机在不同土壤路面上的行驶平顺性,该文针对车轮―不同土壤地面的接触分析,建立了某单钢轮振动压路机非线性动力学模型;描述了振动轮在弹塑性土壤下压实对前车架产生垂直激励力。基于AdamD和KopfF的弹塑性土壤模型,建立了振动轮在作业时的三自由度振动模型;采用软性土壤地面的Bekker假设,建立了轮胎―变形土壤地面接触模型。对建立的非线性动力学模型进行了仿真,并根据ISO2631-1:1997(E)标准分析与评价了不同路况、工况和速度对驾驶员乘坐舒适性的影响。结果表明,刚性路面不平度等级对振动压路机行驶平顺性有较大影响,路面等级越差,驾驶员的主观感觉越不舒适;路面的变形对驾驶室水平晃动有较大影响,土壤路面越软,驾驶室晃动越大;弹塑性土壤对振动压路机的影响表现在低频工况压实时,车辆平顺性比较差。该研究可为振动式压路机的平顺性设计提供参考。 | Le Van Quynh 张建润 刘晓波 王园 P.V.Thoan | 2013 | 农业工程学报2013，29，9： | 10 |
| 7 | Vitamin D deficiency and hepatitis viruses-associated liver diseases:a literature review显示文摘The secosteroid hormone vitamin D has, in addition to its effects in bone metabolism also functions in the modulation of immune responses against infectious agents and in inhibiting tumorigenesis. Thus, deficiency of vitamin D is associated with several malignancies, but also with a plethora of infectious diseases. Among other communicable diseases, vitamin D deficiency is involved in the pathogenesis of chronic liver diseases caused by hepatitis B and C viruses(HBV, HCV) and high prevalence of vitamin D deficiency with serum levels below 20 mg/mL in patients with HBV and HCV infection are found worldwide. Several studies have assessed the effects of vitamin D supplementation on the sustained virological response(SVR) to interferon(IFN) plus ribavirin(RBV) therapy in HBV and HCV infection. In these studies, inconsistent results were reported. This review addresses general aspects of vitamin D deficiency and, in particular, the significance of vitamin D hypovitaminosis in the outcome of HBVand HCV-related chronic liver diseases. Furthermore,current literature was reviewed in order to understand the effects of vitamin D supplementation in combination with IFN-based therapy on the virological response in HBV and HCV infected patients. | Nghiem Xuan Hoan Hoang Van Tong Le Huu Song Christian G Meyer Thirumalaisamy P Velavan | 2018 | World Journal of Gastroenterology2018，24，4： | 9 |
| 8 | Genetic variants of interferon regulatory factor 5 associated with chronic hepatitis B infection显示文摘AIM To investigate possible effects of IRF5 polymorphisms in the 3' UTR region of the IFR5 locus on susceptibilityto hepatitis B virus(HBV) infection and progression of liver diseases among clinically classified Vietnamese patients.METHODS Four IFR5 SNPs(rs13242262 A/T, rs77416878 C/T, rs10488630 A/G, and rs2280714 T/C) were genotyped in clinically classified HBV patients [chronic hepatitis B(CHB). n = 99; liver cirrhosis(LC), n = 131; hepatocellular carcinoma(HCC), n = 149] and in 242 healthy controls by direct sequencing and Taq Man realtime PCR assays. RESULTS Comparing patients and controls, no significant association was observed for the four IFR5 variants. However, the alleles rs13242262 T and rs10488630 G contributed to an increased risk of liver cirrhosis(LC vs CHB: OR = 1.5, 95%CI: 1.1-2.3, adjusted P = 0.04; LC vs CHB: OR = 1.7, 95%CI: 1.1-2.6, adjusted P = 0.019). Haplotype IRF5*TCGT constructed from 4 SNPs was observed frequently in LC compared to CHB patients(OR = 2.1, 95%CI: 1.2-3.3, adjusted P = 0.008). Haplotype IRF5*TCAT occurred rather among CHB patients than in the other HBV patient groups(LC vs CHB: OR = 0.4, 95%CI: 0.2-0.8, adjusted P = 0.03; HCC vs CHB: OR = 0.3, 95%CI: 0.15-0.7, adjusted P = 0.003). The IRF5*TCAT haplotype was also associated with increased levels of ALT, AST and bilirubin. CONCLUSION Our study shows that IFR5 variants may contribute as a host factor in determining the pathogenesis in chronic HBV infections. | Bui Tien Sy Nghiem Xuan Hoan Hoang Van Tong Christian G Meyer Nguyen Linh Toan Le Huu Song Claus-Thomas Bock Thirumalaisamy P Velavan | 2018 | World Journal of Gastroenterology2018，24，2： | 9 |
| 9 | Flexible Wing Kinematics of a Free-Flying Beetle (Rhinoceros Beetle Trypoxylus Dichotomus)显示文摘 | Tien Van Truong Tuyen Quang Le Doyoung Byun Hoon Choel Park Minjun Kim | 2012 | Journal of Bionic Engineering2012，9，2： | 8 |
| 10 | Formal verification of synchronous data-flow program transformations toward certified compilers显示文摘翻译确认被 Pnueli 等在 90 年代发明。作为一种技术到正式验证代码发电机的正确性。而非证明代码生成器或用尽一切地限制它,翻译验证程序试图证实程序转变保存语义。在这个工作,我们采用这条途径正式证实钟语义和数据依赖在信号编译器的编译期间被保存。翻译确认从起始的阶段为每个编译阶段被实现直到可执行的代码被产生的最近的阶段,由证明在编译器的每个阶段的转变保存语义。我们作为分别地被称为钟模型和同步依赖图(SDG ) 的一阶的公式代表钟语义,一个程序的数据依赖和它的转变对应物。我们然后分别地介绍表示钟语义和依赖的保藏的钟精炼和依赖精炼关系,作为钟模型和 SDG 上的一种关系。我们的验证程序不要求编译器,也不任何重写源程序的任何乐器学或修正。 | Van Chan NGO Jean-Pierre TALPIN Thierry GAUTIER Paul Le GUERNIC Loic BESNARD | 2013 | Frontiers of Computer Science2013，7，5： | 7 |
| 11 | Activated carbon derived from rice husk by NaOH activation and its application in supercapacitor显示文摘Four activated carbon(AC) samples prepared from rice husk under different activation temperatures have been characterized by N2adsorption–desorption isotherms, thermogravimetric analysis(TGA–DTA), Fourier transform infrared spectroscopy(FTIR) and scanning electron microscopy(SEM). The specific surface area of AC sample reached 2681 m2 g 1under activation temperature of 800 1C. The AC samples were then tested as electrode material; the specific capacitance of the as-prepared activated carbon electrode was found to be 172.3 F g 1using cyclic voltammetry at a scan rate of 5 mV s 1and 198.4 F g 1at current density 1000 mA g 1in the charge/discharge mode.& 2014 Chinese Materials Research Society. Production and hosting by Elsevier B.V. All rights reserved. | Khu Le Van Thu Thuy Luong Thi | 2014 | Progress in Natural Science:Materials International2014，24，3： | 7 |
| 12 | Silicon and silicon nitride photonic circuits for spectroscopic sensing on-a-chip [Invited]显示文摘There is a rapidly growing demand to use silicon and silicon nitride(Si3N4) integrated photonics for sensing applications, ranging from refractive index to spectroscopic sensing. By making use of advanced CMOS technology,complex miniaturized circuits can be easily realized on a large scale and at a low cost covering visible to mid-IR wavelengths. In this paper we present our recent work on the development of silicon and Si3N4-based photonic integrated circuits for various spectroscopic sensing applications. We report our findings on waveguide-based absorption, and Raman and surface enhanced Raman spectroscopy. Finally we report on-chip spectrometers and on-chip broadband light sources covering very near-IR to mid-IR wavelengths to realize fully integrated spectroscopic systems on a chip. | Ananth Z.Subramanian Eva Ryckeboer Ashim Dhakal Frédéric Peyskens Aditya Malik Bart Kuyken Haolan Zhao Shibnath Pathak Alfonso Ruocco Andreas De Groote Pieter Wuytens Daan Martens Francois Leo Weiqiang Xie Utsav Deepak Dave Muhammad Muneeb Pol Van Dorpe Joris Van Campenhout Wim Bogaerts Peter Bienstman Nicolas Le Thomas Dries Van Thourhout Zeger Hens Gunther Roelkens Roel Baets | 2015 | Photonics Research2015，3，5： | 7 |
| 13 | Graphene-based catalysts for electrochemical carbon dioxide reduction显示文摘Electrochemical carbon dioxide(CO2)reduction is considered to be an efficient strategy to produce usable fuels and overcome the concerns regarding global warming.For this purpose,an efficient,earth abundant,and a low cost catalyst has to be designed.It has been found that graphene-based materials could be promising candidates for CO2 conversion because of their unique physical,mechanical,and electronic properties.In addition,the surface of graphenebased materials can be modified by using different strategies,including doping,defect engineering,producing composite structures,and wrapping shapes.In this review,the fundamentals of electrochemical CO2 reduction and recent progress of graphene-based catalysts are investigated.Furthermore,recent studies on graphene-based materials for CO2 reduction are summarized. | Amirhossein Hasani Mahider Asmare Teklagne Ha Huu Do Sung Hyun Hong Quyet Van Le Sang Hyun Ahn Soo Young Kim | 2020 | Carbon Energy2020，2，2： | 7 |
| 14 | How Could Beetle's Elytra Support Their Own Weight during Forward Flight?显示文摘 | Tuyen Quang Le Tien Van Truong Hieu TrungTran Soo Hyung Park Jin Hwan Ko Hoon Cheol Park Doyoung Byun | 2014 | Journal of Bionic Engineering2014，11，4： | 6 |
| 15 | 基于三维动力学模型的重型卡车动态参数对平顺性的影响显示文摘为了研究重型卡车动态参数对驾驶员舒适性的影响,以路面随机不平度为激扰,以驾驶室座椅垂向、驾驶室的俯仰角和侧倾角的加权加速度均方根值为目标函数,建立了13自由度的三维动力学模型.采用Matlab/Simulink软件对整车模型进行仿真计算,分析了不同系统参数,如悬架、轮胎、驾驶室悬架和驾驶员座椅悬架的参数对驾驶员座椅垂向振动、驾驶室前后和左右晃动的影响.研究结果表明:悬架系统中刚度和阻尼参数的最佳匹配对车辆平顺性的影响非常明显;随着悬架系统和轮胎刚度的增加,车辆平顺性从优向劣转变,而随着悬架系统阻尼的增加,车辆平顺性呈现从劣转优现象.该研究为重型卡车悬架系统设计提供相应的理论依据. | Le Van Quynh 张建润 王园 孙小娟 Nguyen Van Liem | 2013 | 东南大学学报(自然科学版)2013，43，4： | 6 |
| 16 | The No Apical Meristem Gene of Petunia Is Required for Pattern Formation in Embryos and Flowers and Is Expressed at Meristem and Primordia Boundaries显示文摘 | Erik Souer Adèle van Houwelingen Daisy Kloos Jos Mol Ronald Koes | 1996 | Cell1996，，2： | 5 |
| 17 | Flow Visualization of Rhinoceros Beetle (Trypoxylus dichotomus) in Free Flight显示文摘 | Tien Van Truong Tuyen Quang Le Hieu Trung Tran Hoon Cheol Parka Kwang Joon Yoon Doyoung Byun | 2012 | Journal of Bionic Engineering2012，9，3： | 4 |
| 18 | Clinical End Points in Coronary Stent Trials: A Case for Standardized Definitions显示文摘 | Donald E. Cutlip Stephan Windecker Roxana Mehran Ashley Boam David J. Cohen Gerrit-Anne van Es P Gabriel Steg Marie-angèle Morel Laura Mauri Pascal Vranckx Eugene McFadden Alexandra Lansky Martial Hamon Mitchell W. Krucoff Patrick W. Serruys | 2007 | Circulation2007，，17： | 4 |
| 19 | 东亚气候变化与可持续发展——影响与政策挑战(英文)显示文摘气候变化已成为全球,特别是东亚国家可持续发展的挑战性问题。东亚地区由于海岸线长,人口密度大,经济对农业和资源依赖性强,极容易受气候变化的影响,而且影响深,持续时间长,制约了经济和社会的可持续发展。由于快速的城市化、工业化和经济发展,气候变化对资源和环境也构成威胁,使国家在食品安全、能源安全、环境和资源、减少碳排放和社会安全等方面的政策面临挑战。 | LE Thi Thuy Van | 2012 | 资源与产业2012，14，6： | 3 |
| 20 | 母树径级与贮藏对胖大海种子发芽率的影响显示文摘探讨母树径级、贮藏温度及贮藏时间对胖大海种子发芽率的影响.观察不同贮藏条件下种子的发芽情况,通过指数函数建立不同贮藏温度下胖大海种子发芽率与母树径级及贮藏时间的关系模型.结果表明:母树直径50~59 cm提供的种子发芽率、活力最大;母树直径<30 cm提供的种子发芽率、活力最小.0℃贮藏下种子的平均发芽率最高,常温贮藏下最低.胖大海种子的活力和发芽率随贮藏时间的延长而降低,保持种子50%的发芽率,其在-5℃、0℃和常温3个贮藏温度下分别不能长于135、195、45 d.综合分析表明,直径过大或过小的母树提供的种子发芽率均较低,从母树直径50~59 cm选种最佳,最好在0℃环境下贮藏种子,可以延长种子寿命至195 d,但胖大海种子不宜长久贮藏,优质的胖大海种子贮藏时间不能超过270 d.这为胖大海优种选择、贮藏及复壮生产提供了依据. | 张巧巧 PHAM Van Huong 陈昌雄 LE Thi Hien 陈世品 | 2017 | 福建农林大学学报(自然科学版)2017，46，2： | 3 |
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