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| 1 | Systematic mechanism-orientated approach to chronic pancreatitis pain显示文摘Pain in chronic pancreatitis(CP) shows similarities with other visceral pain syndromes(i.e.,inflammatory bowel disease and esophagitis),which should thus be managed in a similar fashion.Typical causes of CP pain include increased intrapancreatic pressure,pancreatic inflammation and pancreatic/extrapancreatic complications.Unfortunately,CP pain continues to be a major clinical challenge.It is recognized that ongoing pain may induce altered central pain processing,e.g.,central sensitization or pro-nociceptive pain modulation.When this is present conventional pain treatment targeting the nociceptive focus,e.g.,opioid analgesia or surgical/endoscopic intervention,often fails even if technically successful.If central nervous system pain processing is altered,specific treatment targeting these changes should be instituted(e.g.,gabapentinoids,ketamine or tricyclic antidepressants).Suitable tools are now available to make altered central processing visible,including quantitative sensory testing,electroencephalograpy and(functional) magnetic resonance imaging.These techniques are potentially clinically useful diagnostic tools to analyze central pain processing and thus define optimum management approaches for pain in CP and other visceral pain syndromes.The present review proposes a systematic mechanism-orientated approach to pain management in CP based on a holistic view of the mechanisms involved.Future research should address the circumstances under which central nervous system pain processing changes in CP,and how this is influenced by ongoing nociceptive input and therapies.Thus we hope to predict which patients are at risk for developing chronic pain or not responding to therapy,leading to improved treatment of chronic pain in CP and other visceral pain disorders. | Stefan AW Bouwense Marjan de Vries Luuk TW Schreuder Soren S Olesen Jens B Frokjær Asbjorn M Drewes Harry van Goor Oliver HG Wilder-Smith | 2015 | World Journal of Gastroenterology2015，21，1： | 6 |
| 2 | Minimally invasive versus open oesophagectomy for patients with oesophageal cancer: a multicentre, open-label, randomised controlled trial显示文摘 | Surya SAY Biere Mark I van Berge Henegouwen Kirsten W Maas Luigi Bonavina Camiel Rosman Josep Roig Garcia Suzanne S Gisbertz Jean HG Klinkenbijl Markus W Hollmann Elly SM de Lange H Jaap Bonjer Donald L van der Peet Miguel A Cuesta | 2012 | The Lancet . 2012 (9829)2012，，： | 3 |
| 3 | Personalized dementia care : proven effectiveness of psychosocial interventions in sub- groups 显示文摘 | Van Mierlo LD Vander Roest HG Meiland FJ | 2010 | Ageing Res Rev2010，9，： | 1 |
| 4 | Using poka-yoke methods to improve employment potential of intellectually disabled workers显示文摘 | TREURNICHT NF BLANCKENBERG MM VAN NIEKERK HG | 2011 | South African Journal oflndustrial Engineering2011，22，1： | 1 |
| 5 | Impulse oscillometry:A measure for airway obstruction显示文摘 | Vink GR Arets HG van der laag J | 2003 | Pediatr Pulmonol2003，35，3： | 1 |
| 6 | Paired measurements of quantitative hepatitis B virus DNA in saliva and serum of chronic hepatitis B patients:implications for saliva as infection agent显示文摘 | Van der Eijk AA Niesters HG Gotz HM | 2004 | J Clin Virol2004，29，2： | 1 |
| 7 | Ongoing pregnancy rates in in vitro fertilization are not dependent on the physician performing the embryo transfer显示文摘 | van Weering HG Schats R McDonnell J | 2005 | Fertil Steril2005，83，2： | 1 |
| 8 | Spontaneous calcium oscillations control c-fos transcription via the serum response element in neuroedocrine cells显示文摘 | Maturana A Van HG Piuz L | 2002 | J Bion Chem2002，277，39： | 1 |
| 9 | Impulse oscillometry:A measure for airway obstruction 显示文摘 | Vink GR Arets HG van der laag J | 2003 | Pediatr Pulmonol2003，35，3： | 1 |
| 10 | The in- fluence of surgical experience on the rate of intraoperative aneurysm rupture and its impact on aneurysm treatment outcome 显示文摘 | Van Lindert E J Bocher Schwarz HG Perneczky A | 2001 | Surg Neurol2001，56，3： | 1 |
| 11 | Using poka-yoke methods to improve employment potential of intellectually disabled workers 显示文摘 | TREURNICHT NF BLANCKENBERG MM VAN NIEKERK HG | 2011 | South African Journal oflndustrial Engineering2011，22，1： | 1 |
| 12 | Personalized de- mentia care: proven effectiveness of psychosocial interventions in subgroups显示文摘 | Van Mierlo LD Van der Roest HG Meiland FJ | 2010 | Ageing Res Rev2010，9，10： | 1 |
| 13 | Personalised caregiver support:effectiveness of psychosocial interventions in subgroups of caregivers of People with dementia显示文摘 | Van Mierlo LD Meiland FJ Van Der Roest HG | 2012 | Int J Geriatr Psychiatry2012，27，1： | 1 |
| 14 | Changes in cortical thickness during the course of illness in schizophrenia 显示文摘 | van Haren NE Schnack HG Cahn W | 2011 | Arch Gen Psychiatry2011，68，： | 1 |
| 15 | Baerveldt Glaucoma implant in paediatric patients 显示文摘 | Van Overdam KA de Faber JT Lemij HG | 2006 | Ophthal mol2006，90，3： | 1 |
| 16 | Pim1 regulates androgen-dependent survival signaling in prostate cancer cells显示文摘 | van der Poel HG Zevenhoven J Bergman AM | | 0，，02： | 1 |
| 17 | Minimally invasive versus open oesophagectomy for patients with oesophageal cancer: a multicentre, open-label, randomised controlled trial显示文摘 | Surya SAY Biere Mark I van Berge Henegouwen Kirsten W Maas Luigi Bonavina Camiel Rosman Josep Roig Garcia Suzanne S Gisbertz Jean HG Klinkenbijl Markus W Hollmann Elly SM de Lange H Jaap Bonjer Donald L van der Peet Miguel A Cuesta | 2012 | The Lancet2012，，9829： | 1 |
| 18 | Metastasectomy in renal cell carcinoma: a multieenter retrospective analysis显示文摘 | VAN DER POEL HG ROUKEMA JA HORENBLAS S | 1999 | Eur Urol1999，35，： | 1 |
| 19 | Usage patterns of benzodiazepines in a dutch community: a 10-year follow-up显示文摘 | Van Hulten R Leufkens HG Bakker A | 1998 | Pharm World Sci1998，20，： | 1 |
| 20 | The biology of transferrin显示文摘 | de Jong G van Dijk JP van Eijk HG | 1990 | Clin Chim Acta1990，190，12： | 1 |
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