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| 1 | Anti-oxidant and anti-inflammatory activity of leaf extracts and fractions of Mangifera indica显示文摘Objective:To evaluate the anti-oxidani and anti-inflammatory activity of leaf extracts and fractions of Mangifera indica in in vitro conditions.Methods:In vitro DPPH radical scavenging activity and lipoxygenase(LOX) inhibition assays were used to evaluate the anti-oxidant and anti-inflammatory activities respectively.Methanolic extract(MEMI),successive water extract (SWMI) and ethyl acetate fraction(EMEMI),n-butanol fraction(BMEMI) and water soluble fraction (WMEMI) of methanolic extract were evaluated along with respective reference standards. Results:In in ritro DPPH radical scavenging activity,the MEMI,EMEMI and BMEMI have offered significant antioxidant activity with IC50 values of 13.37.3.55 and 14.19μig/mL respectively.Gallic acid,a reference standard showed significant antioxidant activity with IC? value of 1.88 and found to be more potent compared to all the extracts and fractions.In m vitro LOX inhibition assay,the MEMI,EMEMI and BMEMI have showed significant inhibition of LOX enzyme activity with IC50 values of 96.71.63.21 and 107.44μg/mL respectively.While,reference drug Indometlhacin also offered significant inhibtion against LOX enzyme activity with IC50 of 57.75.Furthermore,MEMI was found to more potent than SWMI and among the fractions EMEMI was found to possess more potent antioxidant and anti-inflammatory activity.Conclusions:These findings suggest that the MEMI and F.MEMT possess potent anti-oxidani and anti-inflammatory activities in in vitro conditions. | Mohan CG Deepak M Viswanatha GL Savinay G Hanumantharaju V Rajendra CE Praveen D Halemani | 2013 | Asian Pacific Journal of Tropical Medicine2013，6，4： | 2 |
| 2 | 998 Modulation of insulin-like growth factor actions in L6A1 myoblasts by insulin-like growth factor binding protein (IGFBP)-4 and IGFBP-5:a dual role for IGFBP-5显示文摘 | EWTON D Z COOLICAN S A MOHAN S | 1998 | J Cell Physiol1998，177，： | 1 |
| 3 | Studies on distribution and fractionation of heavy metals in Gomti river sediments-a tributary of the Ganges, india显示文摘 | SINGH K P MOHAN D SINGH V K | 2005 | Journal of Hydrology2005，312，： | 1 |
| 4 | Donor-specific antibodies adversely affect kidney allograft out-comes显示文摘 | Mohan S Palanisamy A Tsapepas D | 2012 | J Am Soc Nephrol2012，23，12： | 1 |
| 5 | Evaluating the role of inflam- mation in chronic airways disease: the ERICA study显示文摘 | Mohan D Gale NS McEniery CM | 2014 | COPD2014，11，5： | 1 |
| 6 | Synthesis of casein-g-poly(butyl acrylate)显示文摘 | Mohan D Radhakrishnan G Rajadurai S | 1980 | J Appl Polym Sci1980，25，： | 1 |
| 7 | Bioremediation of anthracene contaminated soil in bio-slurry phase reactor operated in periodic discontinuous batch mode显示文摘 | PRASANNA D VENKATA Mohan S PURUSHOTHAM R B | 2008 | Journal of Hazardous Materials2008，，153： | 1 |
| 8 | Trivalent chromium removal from wastewater using low cost activated carbon derived from agricultural waste material and activated carbon fabric cloth显示文摘 | Mohan D Singh K P Singh V K | 2006 | Hazard Mater2006，135，： | 1 |
| 9 | Reducing motor vehicle crash deaths and injuries in newly motorizing countries显示文摘 | O' Neill B Mohan D | 2002 | BMJ2002，324，： | 1 |
| 10 | On a Pure Finite-Element-Based Methodology for Resin Transfer Mold Filling Simulation显示文摘 | Mohan R V Ngo N D Tamma K K | 1999 | Polymer Engineering and Science1999，39，1： | 1 |
| 11 | Analysis of integrated solenoid inductor with closed magnetic core 显示文摘 | WRIGHT J M LEE D W MOHAN Av | 2010 | IEEE Transactions on Magnetics2010，46，： | 1 |
| 12 | Identification and characterization of a principal oxidation impurity in clopidogrel drug substance and drug product显示文摘 | Mohan A Hariharan M Vikraman E Subbaiah G Venkataraman B R Saravanan D | 2008 | J Pharm Biomed Anal2008，47，： | 1 |
| 13 | Evolving an optimal composition of HFC407C/HC290/ HC600a mixture as an alternative to HCFC22 in window air conditioners显示文摘 | JABARAJ D B NARENDRAN A MOHAN L D | 2007 | International Journal of Thermal Sciences2007，46，3： | 1 |
| 14 | Pregnancy-associated plasma protein-A accounts for the insulinlike growth factor(IGF)-binding protein-4(IGFBP-4) proteolytic activity in human pregnancy serum and enhances the mitogenic activity of IGF by degrading IGFBP-4 in vitro 显示文摘 | Byun D Mohan S Yoo M | 2001 | Clin Endocrinol Metab2001，86，2： | 1 |
| 15 | Synthesis of casein-g-poly(n-butyl methacrylate)显示文摘 | Mohan D Radhakrishnan G Rajadurai S | 1985 | J Macromol Sci Chem1985，22，： | 1 |
| 16 | Bearing capacity of multiple un- derreamed bored piles 显示文摘 | Mohan D Jain G S Sharma D | 1967 | Proceedings 3rd Asian Regional Con-ference on Soil Mechanics and Foundation Engineering Haifa1967，1，： | 1 |
| 17 | Studies on distribution and fractionation of heavy metals in Gomti river sediments-a rributary of the Ganges,India显示文摘 | SINGH K P MOHAN D SINGH V K | 2005 | Journal of Hydrology2005，312，： | 1 |
| 18 | Modulation of Insulin-Like Growth Factor Acfons in L6A1 Myoblasts by Insulin- Like Growth Factor Binding Protein (IGFBP)-4 and IGFBP-5: a Dual Role for IGFBP-5显示文摘 | EWTON D Z COOLICAN S A MOHAN S | 1998 | J Cell Physiol1998，177，： | 1 |
| 19 | Organic and InorganicContaminants Removal From Water With Biochar,a Renewable,Low Cost and Sustainable Adsorbent:A Critical Review显示文摘 | MOHAN D SARSWA T A YONG S | 2014 | Biore-source Technology2014，160，1： | 1 |
| 20 | Synthesis of casein-g-poly(methyl acrylate) II显示文摘 | Mohan D Radhakrishnan G Rajadurai S | 1990 | J Appl Polym Sci1990，39，： | 1 |
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