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| 1 | An overlap syndrome involving autoimmune hepatitis and systemic lupus erythematosus in childhood显示文摘We report a 12 years old female patient with an overlap syndrome involving autoimmune hepatitis (AIH) and systemic lupus erythematosus (SLE). The patient presented with jaundice, hepatosplenomegaly, malaise, polyarthralgia, arthritis and butterfly rash on the face. Laboratory tests revealed severe liver dysfunction, Coombs positive hemolytic anemia and a positive ANA/anti-dsDNA test. Renal biopsy showed class IIA kidney disease, while liver biopsy showed chronic hepatitis with severe in? ammatory activity. The patient satisfi ed the international criteria for both SLE and AIH. Clinical symptoms and laboratory findings of SLE improved with high dose treatment with corticosteroids and azathioprine, however, remission of the liver disease could not be achieved. Repeat biopsy of the liver after three years of therapy revealed ongoing chronic hepatitis with high level of in? ammatory activity. The present case indicates that children with liver dysfunction and SLE should be investigated for AIH. There is much diagnostic and therapeutic dilemma in patients with AIH-SLE overlap syndrome. | Yusuf Usta Figen Gurakan Zuhal Akcoren Seza Ozen | 2007 | World Journal of Gastroenterology2007,13,19: | 7 |
| 2 | Update on pharmacological treatment of acute coronary syndrome without persistent ST segment elevation myocardial infarction in the elderly显示文摘 | Coskun Usta Ash Bedel | 2017 | Journal of Geriatric Cardiology2017,14,7: | 6 |
| 3 | Modeling surface fuels moisture content in Pinus brutia stands显示文摘Fuel moisture content is an important variable for forest fires because it affects fuel ignition and fire behavior. In order to accurately predict fuel ignition potential, fuel moisture content must be assessed by evaluating fire spread, fireline intensity and fuel consumption.Our objective here is to model moisture content of surface fuels in normally stocked Calabrian pine(Pinus brutia Ten.) stands in relation to weather conditions, namely temperature, relative humidity, and wind speed in the Mugla province of Turkey. All surface fuels were categorized according to diameter classes and fuel types. Six fuel categories were defined: these were 0–0.3, 0.3–0.6, and0.6–1 cm diameter classes, and cone, surface litter, and duff. Plastic containers 15 9 20 cm in size with 1 9 1 mm mesh size were used. Samples were taken from 09:00 to19:00 h and weighed every 2 h with 0.01 g precision for10 days in August. At the end of the study, samples were taken to the laboratory, oven-dried at 105 °C for 24 h and weighed to obtain fuel-moisture contents. Weather measurements were taken from a fully automated weather station set up at the study site prior to the study. Correlation and regression analyses were carried out and models were developed to predict fuel moisture contents for desorption and adsorption phase for each fuel type categories. Practical fuel moisture prediction models were developed for dry period. Models were developed that performed well with reasonable accuracy, explaining up to 92 and 95.6%of the variability in fuel-moisture contents for desorption and adsorption phases, respectively. Validation of the models were conducted using an independent data set and known fuel moisture prediction models. The predictive power of the models was satisfactory with mean absolute error values being 1.48 and 1.02 for desorption and adsorption as compared to the 2.05 and 1.60 values for the Van Wagner's hourly litter moisture content prediction model. Results obtained in this study will be invaluable for fire management planning and modeling. | Ertugrul Bilgili Kadir Alperen Coskuner Yetkin Usta Merih Goltas | 2019 | Journal of Forestry Research2019,30,2: | 6 |
| 4 | 西地那非能改善慢性肾功能衰竭大鼠的勃起功能显示文摘勃起功能障碍(ED)和慢性肾衰竭(CRF)之间的关系已在几个研究中被报道。本研究旨在探讨长期使用西地那非是否能增强CRF诱导大鼠的勃起能力。此外,我们评估了该治疗对某些分子的影响,这些分子被认为在勃起生理学及CRF相关的ED中起关键作用。研究分三组:(1)年龄配对的对照组,(2)CRF诱导的大鼠模型组,(3)CRF诱导大鼠给予西地那非慢性给药组((5 mg /kg口服6周[CRF诱导后6周开始治疗])。 3个月时,所有的动物进行海绵体神经刺激(CNS)来评估勃起功能。在所有大鼠组进行,阴茎组织晚期糖化终产物(AGE的) / 5-羟甲基-2-糠醛,丙二醛(MDA),cGMP(ELISA),诱导型一氧化氮合酶(iNOS)和神经元型NOS(nNOS的)(Western印迹)分析。CRF诱导大鼠与对照组相比,勃起功能有显著降低(P 〈0.05)。CRF诱导大鼠西地那非治疗组(第3组),海绵体内压(ICP)和曲线下面积的
增加量,大于CRF诱导大鼠组(第2组)。此外,西地那非治疗下调了AGE,MDA和iNOS的水平,同时保持了CRF诱导阴茎组织的nNOS和cGMP含量。西地那非治疗组AGE,MDA,iNOS的下降和nNOS,cGMP水平的增加,增加了ICP和海绵体神经刺激(CNS)的总ICP,使得CRF诱导大鼠阴茎勃起功能得到改善。本研究的结果表明慢性西地那非给药对CRF诱导大鼠的勃起功能有治疗效果。 | Nilgun Gurbuz Arif Kol Tumay Ipekci Erhan Ates Asli Baykal Mustafa F Usta | 2015 | Asian Journal of Andrology2015,17,5: | 3 |
| 5 | Hypogonadism and erectile dysfunction: an overview显示文摘在人,雄激素衰落表现为包括减少的性兴趣的一幅临床的图画,减少的可勃起的 capasity,推迟或不在的高潮和减少的性快乐。另外,在心情,是的减少的井,疲劳,消沉和易怒变化也与雄激素不足被联系。在阴茎的发展,生长,和 maintanence 的雄激素的关键角色广泛地被接受了。尽管,可勃起的生理学上的雄激素的准确效果仍然保持未经决定,最近的试验性的研究有关于在雄激素和可勃起的功能之间的关系拓宽我们的理解。现出症状之前的潜的研究证明雄激素剥夺在阴茎的神经结构导致阴茎织物萎缩和改变。而且,雄激素剥夺引起了到包含房间的脂肪的累积并且减少内皮和神经元的氮的氧化物 synthases (eNOS 和 nNOS ) 的蛋白质表示,和磷酸二酯酶 type-5 (PDE-5 ) ,哪个戏在正常的关键角色可勃起的生理学。在最近的文学的光上,我们试图也在阴茎织物和可勃起的生理学的结构,开发和 maintanence 上介绍雄激素的直接效果。Furhermore,根据临床的研究,我们在使人变老结束原因论,病理生理学, prevalance,诊断和性腺机能减退的治疗选择。 | Nilgun Gurbuz Elnur Mammadov Mustafa Faruk Usta | 2008 | Asian Journal of Andrology2008,10,1: | 3 |
| 6 | An investigation on boriding kinetics of AISI 316 stainless steel显示文摘 | O. Ozdemir M.A. Omar M. Usta S. Zeytin C. Bindal A.H. Ucisik | 2008 | Vacuum2008,,1: | 2 |
| 7 | Evaluation of penile hemodynamic status and adjustment of treatment alternatives in Peyronie's disease显示文摘Aim:Erectile dysfunction may be observed in up to 80%of patients with Peyronis's disease.An objective evaluation of the erectile function is attempted to work out in patients with Peyronie's disease.Methods:Penile deformity,sexual function and penile vascular status were analyzed in 123patients with Peyronis's disease,who had not received any pertinent treatment.Results:Penile edformity,palpable plaque and pain on erection were seen in112(91%),97(78.8%)and27(21.9%)of the123patients,respectively.Of the 76patients evaluated by color Doppler ultrasounography,veno-occlusive dysfunction as the vascular component for erectile dysfunction was found in 17(22.3%),arterial insufficiency in10(13.1%)and a mixed picture in 23(30.2%).Conclusion:The documentation of penile erectile function and the determination of the vascular status using color Doppler ultrasonography can guide the appropriate therapeutic choice. | Tibet Erdogru Murat Savas Namik Yilmaz Mustafa Faruk Usta Turker Koksal Mutlu Ates Mehmet Baykara | 2002 | Asian Journal of Andrology2002,4,3: | 2 |
| 8 | RhoA/Rho -kinase suppresses endothelial nitric oxide synthase in the penis: A mechanism for diabetes associated erectile dysfunction 显示文摘 | Bivalacqua TJ Champion HC Usta MF etal | 2004 | Proc Natl Acad Sci USA2004,101,24: | 1 |
| 9 | Patient and partner satisfaction and long-term results after surgical treatment for Peyronie's disease 显示文摘 | Usta M F Bivalacqua T J Sanabria J | 2003 | Urology2003,62,: | 1 |
| 10 | 2-D and 3-D modulated porous coatings for enhanced pool boiling 显示文摘 | MIND H HWANG G S USTA Y | 2009 | International Journal of Heat and Mass Transfer2009,,1112: | 1 |
| 11 | Primary primitive neuroectodermal tumor of the lumbar extradural space显示文摘 | Ozdemir N Usta G Minoglu M | 2008 | J Neurosurg Pediatri2008,2,3: | 1 |
| 12 | Effect of combination endothelial nitric oxide synthase gene therapy and sildenafil on erectile function in diabetic rats显示文摘 | Bivalacqua TJ Usta MF Champion HC | 2004 | Int J Impot Res2004,16,1: | 1 |
| 13 | Current obstetrieal practice and umbilical cord prolapse显示文摘 | Usta IM MercerBM Sibai BM | 1999 | Am J Perination1999,16,9: | 1 |
| 14 | Comparison of Misoprostol and Manual Vacuum Aspiration for the Treatment of Incomplete Abortion显示文摘 | Bique C M Usta B Debora | 2007 | Int J Gynaecol Obstet2007,98,3: | 1 |
| 15 | Supercooling as a viable non- freezing cell preservation method of rat hepatocytes显示文摘 | Usta OB Kim Y Ozer S | 2013 | PLoS One2013,8,69: | 1 |
| 16 | The effect of dexmedetomidine on liver histopathology in a rat sepsis model:an experimental pilot study 显示文摘 | Sezer A Memis D Usta U | 2010 | Ulus Travma Acil Cerrahi Derg2010,32,11: | 1 |
| 17 | Effect of cinnamon,clove and some of their constituents on the Na+-K+-ATPase activity and alanine absorption in the rat jejunum显示文摘 | KREYDIYYEH S I USTA J COPTI R | 2000 | Food and chemical toxicology2000,38,: | 1 |
| 18 | The breakdown of preformed advanced glycation end products reverses erectile dysfunction in streptozotocininduced diabetic rats: preventive versus curative treatment 显示文摘 | Usta MF Kendirci M Gur S etal | 2006 | J SexMed2006,3,24: | 1 |
| 19 | Placenta previa-accreta: risk factors and complications显示文摘 | Usta IM Hobeika EM Musa AA | 2005 | Am J Obstet Gyneco]2005,193,3: | 1 |
| 20 | The effect of Saccharomyces boulardii on reducing irinotecan-induced intestinal mucositis and diarrhea 显示文摘 | Sezer A Usta U Cicin I | 2009 | Med Oncol2009,26,3: | 1 |