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20篇 您的检索式:作者名="B Debora"
    题名 作者 年代 出处 被引量
1Comparison of Misoprostol and Manual Vacuum Aspiration for the Treatment of Incomplete Abortion显示文摘Bique C M Usta B Debora 2007Int J Gynaecol Obstet2007,98,3:1
2A known SOST gene mutation causes sclerosteosis in a familial and an iso- lated case from Brazilian origin 显示文摘Chong AK Rachel H Debora B 2008Gentic Tes2008,,:1
3Sensory memory during physiological aging indexed by mismatch negativity (MMN)显示文摘Manuela R Cornelia P Debora B 2012Neurobiology of Aging2012,625,:1
4Comparison of misoprostol and manual vacuum aspiration for the treatment of incomplete abortion 显示文摘Bique C Usta M Debora B 2007Int J Gynaecol Obstet2007,98,3:1
5Vairetal and processingef fects on the volatile profile of Auatralian olive oils显示文摘Debora T Paul D P Danny R B 2004Food Chemistry2004,,8:1
6C-fos gene and protein expression in pelvic endometriosis: a local marker of estrogen action显示文摘Debora M Morsch 'Marcia M Cameiro 'Sheila B 2009J MolHist2009,40,:1
7Thermal degradation and fire resistance of epoxy-amine-phenolic blends显示文摘Debora PIlglia Manfredi Liliana B Analia Vazquez 2001Polymer Degradation and Stability2001,73,:1
8Surfaetant aggregates hosting a photoresponsive amphiphile: structure and photoindueed conformational changes 显示文摘BONINI M DEBORA B MEGLIO J M 2005Soft Matter2005,1,6:1
9Exercise tolerance in asympto- matic patients with moderate-severe valvular heart disease and pre served ejection fraction显示文摘Olaf S Debora E Ricarda B 2012Arch Med Sci2012,8,6:1
10Ef- fects of Pseudomonas putida modified to produce phenazine-1- carboxylic acid and 2,4-diacetylphloroglucinol on the microflo- ra of field grown wheat显示文摘PETER A H M B DEBORA C M G MAREIKE V 2002Kluwer Academic Publishers2002,81,:1
11Comparison of misoprostol and manua| vacuum aspiration for the treatment of incomplete abortion显示文摘Bique C M Usta B Debora 2007Int J Gynaecol Obstet2007,98,3:1
12Artificial neural network for Cu quantitative determination in soil using a portable laser induced breakdown spectroscopy system显示文摘Edilene C Ferreira Debora M B P Milori Ednaldo J Fer- reira 2008Spectrochimica Ac- ta Part B2008,63,:1
13Study of the growth process of in situ polyaniline deposited films 显示文摘Silmar A T Nara C de Souza Debora T B 2007Journal of Colloid and Interface Science2007,316,2:1
14Zinc transporter 8 autoanti- bodies in patients with type 1 diabetes from a multiethnic population and their first degree relatives显示文摘Debora BA Hanna S Bianca B 2014Arq Bras Endocrinol Metab2014,58,7:1
15Trypanocidal tetrahydrofuran lignans from Peperomia blanda 显示文摘Lidiane G F Debora C B Massuo J K 2008Phytochemistry2008,69,:1
16Exercise tolerance in asymptomatic patients with moderate-severe valvular heart disease and preserved ejection fraction 显示文摘Olaf S Debora B Ricarda B 2012Arch Med Sci2012,8,6:1
17Thermal degradation and fire resistance of epoxy-amine-phenolic blends 显示文摘Debora Puglia Manfredi Liliana B Analia Vazquez 2001Polymer Degradation and Stability2001,73,:1
18Hypofractionated radiother- apy after conservative surgery for breast cancer:analysis of acute and late toxicity 显示文摘Letizia D Giuseppina G Debora B 2010Radiation Oncology2010,5,:1
19B-1 cells modulate the murine macrophage response to Leishmania major infection显示文摘AIM To investigate the modulatory effect of B-1 cells on murine peritoneal macrophages infected with Leishmania major(L. major) in vitro.METHODS Peritoneal macrophages obtained from BALB/c andBALB/c XID mice were infected with L. major and cultured in the presence or absence of B-1 cells obtained from wild-type BALB/c mice. Intracellular amastigotes were counted, and interleukin-10(IL-10) production was quantified in the cellular supernatants using an enzymelinked immunosorbent assay. The levels of the lipid mediator prostaglandin E2(PGE2) were determined using a PGE2 enzyme immunoassay kit(Cayman Chemical, Ann Arbor, MI), and the number of lipid bodies was quantified in the cytoplasm of infected macrophages in the presence and absence of B-1 cells. Culturing the cells with selective PGE2-neutralizing drugs inhibited PGE2 production and confirmed the role of this lipid mediator in IL-10 production. In contrast, we demonstrated that B-1 cells derived from IL-10 KO mice did not favor the intracellular growth of L. major.RESULTS We report that B-1 cells promote the growth of L. major amastigotes inside peritoneal murine macrophages. We demonstrated that the modulatory effect was independent of physical contact between the cells, suggesting that soluble factor(s) were released into the cultures. We demonstrated in our co-culture system that B-1 cells trigger IL-10 production by L. major-infected macrophages. Furthermore, the increased secretion of IL-10 was attributed to the presence of the lipid mediator PGE2 in supernatants of L. major-infected macrophages. The presence of B-1 cells also favors the production of lipid bodies by infected macrophages. In contrast, we failed to obtain the same effect on parasite replication inside L. major-infected macrophages when the B-1 cells were isolated from IL-10 knockout mice. CONCLUSION Our results show that elevated levels of PGE2 and IL-10 produced by B-1 cells increase L. major growth, as indicated by the number of parasites in cell cultures.Angelica F Arcanjo Marise P Nunes Elias B Silva-Junior Monique Leandro Juliana Dutra Barbosa da Rocha Alexandre Morrot Debora Decote-Ricardo Celio Geraldo Freire-de-Lima 2017World Journal of Biological Chemistry2017,8,2:0
20Neural Correlates of Human Associative Learning显示文摘Lesion studies in animals have associated the amygdala mainly with aversive conditioning,both cued and contextual.However,neurophysiological studies indicate that the amygdala has a role in the processing of positive emotions in some kinds of stimulusreward learning.The aim of the current study was to extend these findings to humans.Functional magnetic resonance imaging was applied to investigate the neural basis of aversive and appetitive conditioning.In the first study,aversive electrical shocks were delivered as either cue or context related.The second study integrated appetitive and aversive conditioning using electric shocks as aversive and monetary rewards as appetitive reinforcers.Differential responses in the amygdala were observed during both cue and contextual conditioning,whereas context conditioning additionally recruited the hippocampus.Amygdala activity was higher for reinforced acoustic stimuli.The findings underline the importance of the amygdala in associative learning,irrespective of the stimulus valence and stimulus type.Andreas Marschner Raffael Kalisch Bram Vervliet Debora Vansteenwegen Christian Büchel 2011Tsinghua Science and Technology2011,16,2:0
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