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| 1 | Stretta:A valuable endoscopic treatment modality for gastroesophageal reflux disease显示文摘One potential option for the management of refractory gastro-esophageal reflux disease(GERD)is the delivery of radiofrequency energy to the gastro-esophageal junction(Stretta).This endoscopic therapy is safe,effective,durable,and repeatable if necessary and serves an unmet need for many GERD sufferers.Stretta could be effective in decreasing esophageal sensitivity to acid and in decreasing the gastro-esophageal junction compliance,which in turn contributes to symptomatic benefit by decreasing refluxate volume.Therefore,Stretta may serve as an endoscopic pain modulator and should be considered in patients with refractory symptoms despite proton pump inhibitors,as well as in patients with functional heartburn. | George Triadafilopoulos | 2014 | World Journal of Gastroenterology2014，20，24： | 17 |
| 2 | Neuro-regulation of lower esophageal sphincter function as treatment for gastroesophageal reflux disease显示文摘The junction between the esophagus and the stomach is a specialized region, composed of lower esophageal sphincter (LES) and its adjacent anatomical structures, the gastric sling and crural diaphragm. Together these structures work in a coordinated manner to allow ingested food into the stomach while preventing reflux of gastric contents across the esophago-gastric junction (EGJ) into the esophagus. The same zone also permits retrograde passage of air and gastric contents into esophagus during belching and vomiting. The precise coordination required to execute such a complicated task is achieved by a finely-regulated high-pressure zone. This zone keeps the junction between esophagus and stomach continuously closed, but is still able to relax briefly via input from inhibitory neurons that are responsible for its innervation. Alterations of the structure and function of the EGJ and the LES may predispose to gastroesophageal reflux disease (GERD). | Anupender Singh Sidhu George Triadafilopoulos | 2008 | World Journal of Gastroenterology2008，14，7： | 6 |
| 3 | Endoscopic appearance of esophageal hematomas显示文摘INTRODUCTIONEsophageal hematomas develop from the dissectionof the mucosa from the muscular layers of theesophageal wall and represent an uncommoncondition affecting all ages.Although the mostcommon cause of esophageal hematomas isiatrogenic mechanical injury-induced by prolongednasogastric intubation,difficult or forcefulendoscopic intubation,or the result of | Rodica Ouatu-Lascar Gayatri Bharadhwaj George Triadafilopoulos | 2000 | World Journal of Gastroenterology2000，6，2： | 5 |
| 4 | Refractory gastroesophageal reflux disease显示文摘Gastroesophageal reflux disease(GERD)is a condition that develops when the reflux of stomach contents into the esophagus causes troublesome symptoms,esophageal injury,and/or complications.Use of proton pump inhibitors(PPI)remains the standard therapy for GERD and is effective in most patients.Those whose symptoms are refractory to PPIs should be evaluated further and other treatment options should be considered,according to individual patient characteristics.Response to PPIs could be total(no symptoms),partial(residual breakthrough symptoms),or absent(no change in symptoms).Patients experiencing complete response do not usually need further management.Patients with partial response can be treated surgically or by using emerging endoscopic therapies.Patients who exhibit no response to PPI need further evaluation to rule out other causes. | Charumathi Raghu Subramanian George Triadafilopoulos | 2015 | Gastroenterology Report2015，3，1： | 5 |
| 5 | Gastric per-oral endoscopic myotomy: Current status and future directions显示文摘Gastroparesis, or symptomatic delayed gastric emptying in the absence of mechanical obstruction, is a challenging and increasingly identified syndrome. Medical options are limited and the only medication approved by the Food and Drug Administration for treatment of gastroparesis is metoclopramide, although other agents are frequently used off label. With this caveat, first-line treatments for gastroparesis include dietary modifications, antiemetics and promotility agents, although these therapies are limited by suboptimal efficacy and significant medication side effects. Treatment of patients that fail first-line treatments represents a significant therapeutic challenge. Recent advances in endoscopic techniques have led to the development of a promising novel endoscopic therapy for gastroparesis via endoscopic pyloromyotomy, also referred to as gastric per-oral endoscopic myotomy or per-oral endoscopic pyloromyotomy. The aim of this article is to review the technical aspects of the per-oral endoscopic myotomy procedure for the treatment of gastroparesis, provide an overview of the currently published literature, and outline potential next directions for the field. | Alexander Podboy Joo Ha Hwang Linda A Nguyen Patricia Garcia Thomas A Zikos Afrin Kamal George Triadafilopoulos John O Clarke | 2019 | World Journal of Gastroenterology2019，25，21： | 3 |
| 6 | Injection therapies for variceal bleeding disorders of the GI tract <ce:link locator='fx1'/>显示文摘 | Walter G. Park Ronald W. Yeh George Triadafilopoulos | 2008 | Gastrointestinal Endoscopy2008，，2： | 2 |
| 7 | Incidence and Risk of Intestinal and Extra-intestinal Complications in Medicaid Patients with Inflammatory Bowel Disease: A 5-Year Population-Based Study显示文摘 | Gaurav Arora Gurkirpal Singh Shweta Vadhavkar Shamita B. Shah Ajitha Mannalithara Alka Mithal George Triadafilopoulos | 2010 | Digestive Diseases and Sciences2010，，6： | 1 |
| 8 | Bowel dysfunction in fibromyalgia syndrome显示文摘 | Dr. George Triadafilopoulos MD Robert W. Simms MD Don L. Goldenberg MD | 1991 | Digestive Diseases and Sciences1991，，1： | 1 |
| 9 | Esophageal mucosal eicosanoids in gastroesophageal reflux disease and Barrett' s esophagus显示文摘 | TRIADAFILOPOULOS G KACZYNSKA M LWANE M | 1996 | Am J Gastroenterol1996，91，1： | 1 |
| 10 | Guide to the use of proton pump inhibitor in adult patients显示文摘 | Boparai V Rajagopalan J Triadafilopoulos G | 2008 | Drugs2008，68，7： | 1 |
| 11 | Prevalence of Barrett's eso- phagus in asymptomatic individuals显示文摘 | Gerson LB Shetler K Triadafilopoulos G | 2002 | Gastroenterology2002，123，： | 1 |
| 12 | A prospective study of oesophageal 24 -h ambulatory pH monitoring in patients with functional dyspepsia 显示文摘 | Gerson LB Triadafilopoulos G | 2005 | Dig Liver Dis2005，37，2： | 1 |
| 13 | Exercise and gastrointestinal function and disease:an evidence-based review of risks and benefits显示文摘 | Bi L Triadafilopoulos G | 2003 | Clin Gastroenterol Hepatol2003，1，5： | 1 |
| 14 | Prospective study of oesophageal 24h ambulatory pH monitoring in patients with functional dyspepsia显示文摘 | Gerson LB Triadafilopoulos G | 2005 | Dig Liver Dis2005，37，2： | 1 |
| 15 | Differentiation and proliferation in Barrett's esophagus and the effects of acid suppression显示文摘 | Ouatu-Lascar R Fitzgerald RC Triadafilopoulos G | 1999 | Gastroenterology1999，117，2： | 1 |
| 16 | Stretta: an effective, minimally invasive treat- ment for gastroesophageal reflux disease 显示文摘 | Triadafilopoulos G | 2003 | Am J Med2003，115，3： | 1 |
| 17 | Differentiation and proliferation in Barrett's esophagus and the effects of acid suppression显示文摘 | Ouatu-Lascar R Fitzgerald RC Triadafilopoulos G | 1999 | Gastroenterology1999，117，2： | 1 |
| 18 | Management of lower gastrointestinal bleeding in older adults显示文摘 | Triadafilopoulos G | | 0，，9： | 1 |
| 19 | Stretta: an effective, minimally invasive treatment for gastroesophageal reflux disease显示文摘 | George Triadafilopoulos | 2003 | The American Journal of Medicine2003，，3： | 1 |
| 20 | Epidemiology of NSAIDS induced gastrointestinal complications显示文摘 | Sigh G Triadafilopoulos G | 1999 | J Rheumatol1999，26，56： | 1 |
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