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| 1 | The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming显示文摘新陈代谢对房间功能的每个方面重要,然而,导致的 pluripotent 干细胞(iPSCs ) 的 metabolome 仍然保持大部分未经勘探。这里,我们报导,用一条 untargeted metabolomics 途径,那人的 iPSCs 份额有从他们的父母房间是不同的胚胎的干细胞(转换字符) 的 pluripotent metabolomic 签名,并且那被变化在涉及细胞的呼吸的代谢物描绘。细胞的 bioenergetics 的检查与我们的 metabolomic 分析支持了,并且证明体的房间在 pluripotency 从一个氧化状态变换成一个 glycolytic 状态。有趣地,各种各样的体的房间的 bioenergetics 与他们的 reprogramming 效率相关。我们进一步识别了在 iPSCs 和转换字符之间不同的代谢物,它揭示了在调整体的房间 reprogramming 起一个关键作用的新奇新陈代谢的小径。我们的调查结果是第一全球性分析 iPSCs 的 metabolome,并且提供机械学的卓见进涉及导致 pluripotency,并且在评估 iPSC 和转换字符等价的规定的新层。 | Athanasia D Panopoulos Oscar Yanes Sergio Ruiz Yasuyuki S Kida Dinh Diep Ralf Tautenhahn Aida Herrerias Erika M Batchelder Nongluk Plongthongkum Margaret Lutz W Travis Berggren Kun Zhang Ronald M Evans Gary Siuzdak Juan Carlos Izpisua Belmonte] | 2012 | Cell Research2012，22，1： | 12 |
| 2 | Second European evidence-based consensus on the diagnosis and management of ulcerative colitis Part 2: Current management显示文摘 | Axel Dignass James O. Lindsay Andreas Sturm Alastair Windsor Jean-Frederic Colombel Mathieu Allez Gert D’Haens André D’Hoore Gerassimos Mantzaris Gottfried Novacek Tom ?resland Walter Reinisch Miquel Sans Eduard Stange Severine Vermeire Simon Travis Gert | 2012 | Journal of Crohn’s and Colitis2012，，10： | 4 |
| 3 | The second European evidence-based Consensus on the diagnosis and management of Crohn’s disease: Current management显示文摘 | A. Dignass G. Van Assche J.O. Lindsay M. Lémann J. S?derholm J.F. Colombel S. Danese A. D’Hoore M. Gassull F. Gomollón D.W. Hommes P. Michetti C. O’Morain T. ?resland A. Windsor E.F. Stange S.P.L. Travis | 2010 | Journal of Crohn’s and Colitis2010，，1： | 2 |
| 4 | European evidence-based Consensus on the management of ulcerative colitis: Current management显示文摘 | S.P.L. Travis E.F. Stange M. Lémann T. ?resland W.A. Bemelman Y. Chowers J.F. Colombel G. D'Haens S. Ghosh P. Marteau W. Kruis N.J.McC. Mortensen F. Penninckx M. Gassull | 2008 | Journal of Crohn’s and Colitis2008，，1： | 2 |
| 5 | Intracralial Delivery of the Nitric Oxide Donor Diethylenetriamine/nitrie Oxide from a Controlledreleasw Polymer : Toxicity in Cynomolgus Monkeys显示文摘 | Travis S Tierney M D | 2006 | Neurosurgery2006，58，： | 1 |
| 6 | Optocoupler simplifies power-line monitoring显示文摘 | TRAVIS B ALFREDO D R | 2002 | 47 (1) : 76-772002，47，1： | 1 |
| 7 | Expression of surfactant associ-ated protein-A and Clara cell 10 kilodahon mRNA in neoplastic and non-neoplastichuman lung tissue as detected by in situ hybridization 显示文摘 | Broers J L Jensen S M Travis W D | 1992 | Lab Invest1992，66，3： | 1 |
| 8 | Conventional medical management of inflammatory bowel disease显示文摘 | Burger D Travis S | | 0，，06： | 1 |
| 9 | An official American Thoracic Society/European Respiratory Society statement: update of the international multidisciplinary classification of the idiopathic interstitial pneumonias显示文摘 | Travis W D Costabel U Hansell D M | 2013 | Am J Respir Crit Care Med2013，188，6： | 1 |
| 10 | Cushing syndrome due to primary pigmented nodular adrenocortical disease:findings at CT and MR imaging显示文摘 | Doppman J L Travis W D Nieman L | 1989 | Radiology1989，172，2： | 1 |
| 11 | Lung cancer 显示文摘 | Travis W D Travis L B Devesa S S | 1995 | Cancer1995，75，1： | 1 |
| 12 | Pathology of lung cancer 显示文摘 | Travis W D | 2002 | Clin Chest Med2002，23，1： | 1 |
| 13 | Ele- vated CO2 increases productivity and invasive species success in an arid ecosystem显示文摘 | STANLEY D S Travis E H Stephen F Z | 2000 | Nature2000，408，2： | 1 |
| 14 | The new world health organization classification of lung tumours 显示文摘 | Brambilla E Travis W D Colby T V | 2001 | Europ Respirat J2001，18，6： | 1 |
| 15 | The 2015 World Health Organization classification of lung tumors: impact of genetic, clinical and radiologic advances since the 2004 classification显示文摘 | TRAVIS W D BRAMBILLA E NICHOLSON A G | 2015 | J Thorae Oneol2015，10，9： | 1 |
| 16 | Immune reconstitution associated with progressive multifocal leukoencephalopathy in human immunodeficiency virus: a case discussion and review of the literature 显示文摘 | Travis J Varma A duPlessis D | 2008 | Neurologist2008，14，： | 1 |
| 17 | Lung cancer 显示文摘 | Travis W D Travis L B Devesa S S | 1995 | Cancer1995，75，1： | 1 |
| 18 | Characterization of a pollen-specific cDNA clone from Zea mays and its expression 显示文摘 | Hanson D D Hamilton D A Travis J L | 1989 | Plant Cell1989，1，2： | 1 |
| 19 | Differential effect of amino acid on nitrate uptake and reduction systems in barley roots显示文摘 | Aslam M Travis R L Rains D W | 2001 | Plant Science2001，160，： | 1 |
| 20 | Diabetic gastroparesis improved by percutaneous endoscopic jejunostomy 显示文摘 | Devendra D Millward BA Travis SP | 2000 | Diabetes Care2000，23，2： | 1 |
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