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| 1 | Vitamin B biosynthesis in higher plants 显示文摘 | B6 status Nutricion sources in American Tambasco-Studart M Titiz O Raschle T | 2005 | Proceedings of the National Academy of Sciences of the United States of America2005，102，13： | 1 |
| 2 | Oxidative stress in portal hypertension-induced rats with particular emphasis on nitric oxide and trace metals显示文摘AIM: To investigate the oxidative-stress-related changes in rats with portal hypertension with particular emphasis on nitric oxide (NO) and trace metals. METHODS: Cirrhosis was induced by partial portal vein ligation (PVL) in Wistar rats. The lipid peroxidation marker (malondialdehyde, MDA), antioxidant defense enzymes including superoxide dismutase (SOD), catalase (CAT), glutathione (GSH), and agents known to have antioxidant features including nitric oxide (NO), zinc (Zn), copper (Cu) were determined both in serum and in liver tissue at 4 wk after surgery in PVL and sham-operated rats. Portal pressure of all experimental animals was measured. MDA was detected by thiobarbituric acid reactivity assay.SOD activity was determined by inhibition of nitroblue tetrazolium reduction with xanthine/xanthine oxidase used asa superoxide generator. CAT activity was determined by the breakdown of hydrogen peroxide. GSH concentrations were measured by using metaphosphoric acid for protein precipitation and 5'-5'-dithio-bis-2-nitrobenzoic acid for color development. NO was detected by the Griess method after reduction of nitrate to nitrite with nitrate reductase, and the concentrations of Zn and Cu were measured by a Shimadzu 680 AA atomic absorption spectrometer. Histopathological confirmation was done under light microscope. Statistical analyses were done by Student's t-test, and significance of the difference was tested by the unpaired Mann-Whitney test. P<0.05 was considered statistically significant.RESULTS: Histopathological studies confirmed PVL induced cirrhotic changes. There was a statistically significant difference in portal pressure between PVL and control groups (P<0.001). The results showed significant increases in the levels of MDA and NO in both tissue and serum (P<0.05 and P<0.001, respectively in tissue; P<0.001 for each in serum), and Zn only in tissue (P<0.001)in rats with PVL compared with sham-operated rats. Besides, PVL rats exhibited reduced plasma and tissue GSH, CAT, SOD (P<0.001 for each). Serum and tissue Cu concentration did not change.CONCLUSION: Our findings suggest that PVL in rats induces important biochemical and molecular changes related to oxidative stress in the liver. | Titiz Izzet Krand Osman Unal Ethem Yavuz Nihat Kusaslan Ramazan Dogan Mustafa Uzun Hafize Kiziler Ali Riza Aydemir Birsen Genc Habibe Aydin Seval Simsek Gonul | 2005 | World Journal of Gastroenterology2005，11，23： | 1 |
| 3 | Comparison of the effect of ketamine added to bupivacaine and ropivacaine,on stress hormone levels and the duration of caudal analgesia显示文摘 | Akbas M Titiz TA Ertugrul F | 2005 | Acta Anaesthesiol Scand2005，49，10： | 1 |
| 4 | Bilateral antrochoanal polyps in an adult:a case report显示文摘 | YILMAZ Y F TITIZ A OZCAN M | 2007 | BENT2007，3，： | 1 |
| 5 | Pretreatment with a very low dose of intravenous esmolol reduces propofol injection pain显示文摘 | AKGUN SALMAN E TITIZ L AKPEK E | 2013 | Agri2013，25，1： | 1 |
| 6 | Bilateral antrochoanal polyps in an adult:a case report显示文摘 | Yilmaz YF Titiz A Ozcan M | 2007 | B-ENT2007，3，2： | 1 |
| 7 | The utility of amylaseand lipase as reliable predictive markers for functioningrenal graft显示文摘 | Yilmaz UE Yilmaz N Titiz I | 2012 | Ann Transplant2012，17，3： | 1 |
| 8 | Quality of Life Analysis of Renal Donors显示文摘 | G. Tellioglu I. Berber I. Yatkin B. Yigit T. Ozgezer S. Gulle G. Isitmangil M. Caliskan I. Titiz | 2008 | Transplantation Proceedings2008，，1： | 1 |
| 9 | Vitamin B6 biosynthesis in higher plants显示文摘 | Tambasco-Studart M Titiz O Raschle T | 2005 | PNAS2005，102，13： | 1 |
| 10 | Comparison of the effect of ketamine added to bupivacaine and ropivaeaine, on stress hormone levels and the duration of caudal analgesia显示文摘 | Akbas M Titiz TA Ertugrul F | 2005 | Acta Anaesthesiol Scand2005，49，10： | 1 |
| 11 | Stone disease in kidney transplantation显示文摘 | Yigit B Aydin C Titiz I | 2004 | Transplant Proc2004，36，1： | 1 |
| 12 | Speed modulation ofhippocampal theta frequency correlates with spatial memory performance 显示文摘 | Richard GR Titiz A Tyler A | 2013 | Hippocampus2013，23，12： | 1 |
| 13 | Development of maxillary accessory ostium following sinusitis in rabbits 显示文摘 | Slahatm Gnc Muge Ozcan Ali Titiz | 2008 | Rhinology2008，46，2： | 1 |
| 14 | Stone disease in kidney transplantation 显示文摘 | Yigit B Aydin C Titiz I | 2004 | Transplant Proc2004，36，1： | 1 |
| 15 | Repeatability and reproducibility of landmarks-a three-dimensional computed tomography study 显示文摘 | Titiz I Laubinger M Keller T | 2012 | Eur J Orthod2012，34，3： | 1 |
| 16 | Vitamin B6 biosynthesis in higher plants显示文摘 | TAMBASCO-STUDARTM TITIZ O RASCHLE T | 2005 | Proceedings of the National Academy of Sciences of the United States of America2005，102，13： | 1 |
| 17 | Vitamin B6 biosynthesis in higher plants显示文摘 | Tambasco-Studart M Titiz O Raschle T | 2005 | PNAS2005，102，13： | 1 |
| 18 | Pre-treatment with a very low dose of intravenous esmolol re-duces propofol injection pain 显示文摘 | Ebru Akgun Salman Lale Titiz Elif Akpek | 2013 | AGRI2013，25，1： | 1 |
| 19 | Pretreatment with a very low dose of intravenous esmolol reduces propofol injection pain显示文摘 | Akgün Salman E Titiz L Akpek E | 2013 | Agri2013，25，1： | 1 |
| 20 | Prognostic parameters for the prediction of acute gangrenous cholecystitis显示文摘 | Cagatay Aydin Gülüm Altaca Ibrahim Berber Koray Tekin Melih Kara Izzet Titiz | 2006 | Journal of Hepato-Biliary-Pancreatic Surgery2006，，2： | 1 |
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