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| 1 | Liver transplantation: Current status and challenges显示文摘Great progress has been made in the field of liver transplantation over the past two decades. This progress, however, also brings up the next set of challenges: First, organ shortage remains a major limitation, and accounts for a large proportion of wait list mortality. While living donation has successfully increased the total number of liver transplants done in Asian countries, the total number of such transplants has been stagnant in the western hemisphere. As such, there has been a significant effort over the past decade to increase the existing deceased donor pool. This effort has resulted in a greater use of liver allografts following donation after cardiac death(DCD) along with marginal and extended criteria donors. Improved understanding of the pathophysiology of liver allografts procured after circulatory arrest has not only resulted in better selection and management of DCD donors, but has also helped in the development of mechanical perfusion strategies. Early outcomes demonstrating the clinical applicability of both hypothermic and normothermic perfusion and its potential to impact patient survival and allograft function have generated much interest. Second, long-term outcomes of liver transplant recipients have not improved significantly, as recipients continue to succumb to complications of long-term immunosuppression, such as infection, malignancy and renal failure. Furthermore, recent evidence suggests that chronic immune-mediated injury to the liver may also impact graft function. | Caroline C Jadlowiec Timucin Taner | 2016 | World Journal of Gastroenterology2016,22,18: | 23 |
| 2 | Revisiting the liver’s role in transplant alloimmunity显示文摘The transplanted liver can modulate the recipient immune system to induce tolerance after transplantation.This phenomenon was observed nearly five decades ago.Subsequently,the liver’s role in multivisceral transplantation was recognized,as it has a protective role in preventing rejection of simultaneously transplanted solid organs such as kidney and heart.The liver has a unique architecture and is home to many cells involved in immunity and inflammation.After transplantation,these cells migrate from the liver into the recipient.Early studies identified chimerism as an important mechanism by which the liver modulates the human immune system.Recent studies on human T-cell subtypes,cytokine expression,and gene expression in the allograft have expanded our knowledge on the potential mechanisms underlying immunomodulation.In this article,we discuss the privileged state of liver transplantation compared to other solid organ transplantation,the liver allograft’s role in multivisceral transplantation,various cells in the liver involved in immune responses,and the potential mechanisms underlying immunomodulation of host alloresponses. | Nitin Abrol Caroline C Jadlowiec Timucin Taner | 2019 | World Journal of Gastroenterology2019,25,25: | 2 |
| 3 | Equilibrium relations in the syslem nickel oxide-copper oxide显示文摘 | Eric H Timucin M | 1979 | Metallurgical Transactions B1979,10,56: | 1 |
| 4 | Posterior iris fixa- tion of the iris-claw intraocular lens implantation through a scleral tunnel incision 显示文摘 | Baykara M Ozcetin H Yilmaz S Timucin OB | 2007 | Am J Ophthalmol2007,144,4: | 1 |
| 5 | Acute pulmonary oedema during cardiac resynchronization therapy device implantation: management with the activation of intra-aortic balloon pump显示文摘 | Timucin A Basar C Demet O | 2008 | Oxford Journals2008,10,10: | 1 |
| 6 | Phase equilibria in the system MgO-B2O3显示文摘 | MUTLUER T TIMUCIN M | 1975 | JAm Ceram Soc1975,58,56: | 1 |
| 7 | Incidence of cystic changes in radiographically normal impacted lower third molar follicls显示文摘 | Ali A Ulkem A | 2005 | Oral Surg Oral Med Oral Pathol Oral Radiol Endod2005,99,5: | 1 |
| 8 | Fabrication and characterization of porous tricalcium phosphate ceramics 显示文摘 | Koc N Timucin M Korkusuz F | 2004 | Ceramics Int2004,,30: | 1 |
| 9 | An investigation of the chemical synthesis and high-temperature sintering behaviour of calcium hydroxyapatite (HA) and tricalcium phosphate (TCP) bioceramics显示文摘 | A CUNEYT TAS F KORKUSUZ M TIMUCIN N AKKAS | 1997 | Journal of Materials Science: Materials in Medicine1997,,2: | 1 |
| 10 | Staple Line Reinforcement Methods in Laparoscopic Sleeve Gastrectomy: Comparison of Burst Pressures and Leaks 显示文摘 | Timucin Aydin M Aras O Karip B | 2015 | JSLS2015,19,3: | 1 |
| 11 | The efficacy of rituximab in patients with splenectomized refractory chronic idiopathic thrombocythopenic purpura显示文摘 | Semir Pasa Abdullah Altintas Timucin Cil Ramazan Danis Orhan Ayyildiz | 2009 | Journal of Thrombosis and Thrombolysis2009,,3: | 1 |
| 12 | Do PFNA devices and Intertan nails both have the same effects in the treatment of trochanteric fractures? A prospective clinical study显示文摘 | Mustafa Seyhan Ismail Turkmen Koray Unay Afsar Timucin Ozkut | 2015 | Journal of Orthopaedic Science2015,,6: | 1 |
| 13 | Phase equilibria in the system MgO- B203 显示文摘 | Mut|uer T Timucin M | 1975 | Journal of the American Ceramic Society1975,58,56: | 1 |
| 14 | Phase Equilibria in the System MgO-B2O3显示文摘 | Mutluer T Timucin M | 1975 | Journal of American Ceramic Society1975,58,56: | 1 |
| 15 | An investigation of the chemical synthesis and high - temperature sintering behavior of calcium hydroxyapatite (HA) and tricalcium phosphate (TCP) bioceramics显示文摘 | Tas AC Korkusuz F Timucin M | 1997 | J of Mater Sci Mater Med1997,8,: | 1 |
| 16 | An investigation of the chemical synthesis and high-temperature sintering behavior of calcium hydroyapatite (HA) and tricalciumphosphate (TCP) bioceramics 显示文摘 | Korkusz F Timucin M | 1997 | ater Sci mater med1997,8,: | 1 |
| 17 | Thermodynamic analysis of the direct converting of lead sulphide显示文摘 | ERIC R H TIMUCIN M | 1989 | Journal of the South African Institute of Mining and Metallurgy1989,89,2: | 1 |
| 18 | Sheehan’s syndrome and its impact on bone mineral density显示文摘 | Deniz Gokalp Alpaslan Tuzcu Mithat Bahceci Senay Arikan Cihan Akgul Ozmen Timucin Cil | 2009 | Gynecological Endocrinology2009,,5: | 1 |
| 19 | Rapamycin inhibits macropinocttosis and mannose receptor-mediated endocytosis by bone marrow-derived dendritic cells显示文摘 | Holger H Timucin T Alison JL | 2002 | Blood2002,100,3: | 1 |
| 20 | Effect of ramipril therapy on abnormal left atrial appendage function显示文摘 | Asker M Timucin OB Asker S | 2011 | J Int Med Res2011,39,6: | 1 |