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1Effect of autotransfusion system on tumor recurrence and survival in hepatocellular carcinoma patients显示文摘AIM:To investigate the therapeutic efficacy and safety of continuous autotransfusion system(CATS) during liver transplantation of hepatocellular carcinoma patients.METHODS:Eighty-three hepatocellular carcinoma(HCC) patients who underwent liver transplantation with intraoperative CATS(n = 24,CATS group) and without(n = 59,non-CATS group) between April 2006 and November 2011 at the Liver Transplant Institute of Inonu University were analyzed retrospectively.Postoperative HCC recurrence was monitored by measuring alpha-fetoprotein(AFP) levels at 3-mo intervals and performing imaging analysis by thoracoabdominal multidetector computed tomography at 6-month intervals.Inter-group differences in recurrence and correlations between demographic,clinical,and pathological data were assessed by ANOVA and χ 2 tests.Overall and disease-free survivals were calculated by the univariate Kaplan-Meier method.RESULTS:Of the 83 liver transplanted HCC patients,89.2% were male and the overall mean age was 51.3 ± 8.9 years(range:18-69 years).The CATS and nonCATS groups showed no statistically significant differences in age,sex ratio,body mass index,underlying disease,donor type,graft-to-recipient weight ratio,Child-Pugh and Model for End-Stage Liver Disease scores,number of tumors,tumor size,AFP level,Milan and University of California San Francisco selection criteria,tumor differentiation,macrovascular invasion,median hospital stay,recurrence rate,recurrence site,or mortality rate.The mean follow-up time of the nonCATS group was 17.9 ± 12.8 mo,during which systemic metastasis and/or locoregional recurrence developed in 25.4% of the patients.The mean follow-up time for the CATS group was 25.8 ± 15.1 mo,during which systemic metastasis and/or locoregional recurrence was detected in 29.2% of the patients.There was no significant difference between the CATS and non-CATS groups in recurrence rate or site.Additionally,no significant differences existed between the groups in overall or disease-free survival.CONCLUSION:CATS is a safe procedure and may decrease the risk of tumor recurrence in HCC patients.Sami Akbulut Cuneyt Kayaalp Mehmet Yilmaz Volkan Ince Dincer Ozgor Koray Karabulut Cengiz Eris Huseyin Ilksen Toprak Cemalettin Aydin Sezai Yilmaz 2013World Journal of Gastroenterology2013,19,10:17
2Pneumatosis cystoides intestinalis:A single center experience显示文摘AIM:To share our experience of the management and outcomes of patients with pneumatosis cystoides intestinalis (PCI).METHODS:The charts of seven patients who underwent surgery for PCI between 2001 and 2009 were reviewed retrospectively.Clinical features,diagnoses and surgical interventions of patients with PCI are discussed.RESULTS:Seven patients with PCI (3 males,4 females;mean age,50 ± 16.1 years;range,29-74 years) were analyzed.In three of the patients,abdominal pain was the only complaint,whereas additional vomiting and/or constipation occurred in four.Leukocytosis was detected in four patients,whereas it was within normal limits in three.Subdiaphragmatic free air was observed radiologically in four patients but not in three.Six of the patients underwent an applied laparotomy,whereas one underwent an applied explorative laparoscopy.PCI localized to the small intestine only was detected in four patients,whereas it was localized to the small intestine and the colon in three.Three patients underwent a partial small intestine resection and four did not after PCI was diagnosed.Five patients were diagnosed with secondary PCI and two with primary PCI when the surgical findings and medical history were assessed together.Gastric atony developed in one case only,as a complication during a postoperative follow-up of 5-14 d.CONCLUSION:Although rare,PCI should be considered in the differential diagnosis of acute abdomen.Diagnostic laparoscopy and preoperative radiological tests,including computed tomography,play an important role in confirming the diagnosis.Zulfu Arikanoglu Erhan Aygen Cemalettin Camci Sami Akbulut Murat Basbug Osman Dogru Ziya Cetinkaya Cuneyt Kirkil 2012World Journal of Gastroenterology2012,18,5:13
3经自然腔道取标本手术(NOSES)治疗结直肠癌的国际共识显示文摘近年来,经自然腔道取标本手术(NOSES)治疗结直肠癌已引起了广泛关注。NOSES应用于结直肠手术的潜在优势包括减轻术后疼痛,减少伤口并发症,减少对术后镇痛的需求,加快肠道功能的恢复,缩短住院时间,更好的美容效果,以及给患者带来了更佳的心理状态。尽管NOSES的手术创伤显著减轻,然而该技术也存在一些潜在问题。尤其随着这项新技术的兴起,人们对其无菌的把控、肿瘤学结果和病例选择等问题表示出关切。因此,迫切需要一部操作指南来规范NOSES手术在结直肠癌中的开展。经过国际NOSES联盟全体成员的三轮讨论,最终形成了该部共识。这一共识有助于NOSES在全球范围内的长远发展。Xu Guan Zheng Liu Antonio Longo Jian-Chun Cai William Tzu-Liang Chen Lu-Chuan Chen Ho-Kyung Chun Joaquim Manuel da Costa Pereira Sergey Efetov Ricardo Escalante Qing-Si He Jun-Hong Hu Cuneyt Kayaalp Seon-Hahn Kim Jim S.Khan Li-Jen Kuo Atsushi Nishimura Fernanda Nogueira Junji Okuda Avanish Saklani Ali A.Shafik Ming-Yin Shen Jung-Tack Son Jun-Min Song Dong-Hui Sun Keisuke Uehara Gui-Yu Wang Ye Wei Zhi-Guo Xiong Hong-Liang Yao Gang Yu Shao-Jun Yu Hai-Tao Zhou Suk-Hwan Lee Petr V.Tsarkov Chuan-Gang Fu Xi-Shan Wang The International Alliance of NOSES 2019Gastroenterology Report2019,7,1:3
4Retinal vessel diameters and their correlation with retinal nerve fiber layer thickness in patients with pseudoexfoliation syndrome显示文摘AIM: To compare retinal artery-vein diameters(RAVDs)of patients with pseudoexfoliation(PSX) syndrome with healthy controls and investigate the correlations between retinal nerve fiber layer(RNFL) thickness parameters and RAVDs.METHODS: Seventeen eyes with PSX and 17 eyes of age-matched controls were included in the study. All participants underwent routine ophthalmological examination, Humphrey visual field and RNFL examination by using Stratus OCT. Retinal images were obtained by using a retinal camera(Topcon 501X).RAVDs were measured from inferior nasal, inferior temporal, superior nasal and superior temporal arcuates by using IMAGEnet software. Superior, inferior, nasal,temporal and average RNFL thicknesses were recorded.RAVDs and RNFL parameters in groups and correlations were analyzed by Mann-Whitney U and Spearmann correlation tests.RESULTS: Only inferior quadrant and average RNFL thickness were detected thinner in the PSX group compared with control group(P =0.009, P =0.038,respectively). No statistically significant difference regarding RAVDs was found between two groups.CONCLUSION: RAVDs seems to be comparable in the PSX and control group. RNFL is thinner in the inferior quadrant in the PSX group. RNFL thickness and RAVDs show significant correlations in both groups. This correlation doesn't seem to be specific to PSX.Mehmet Cuneyt Ozmen Zeynep Aktas Burcin Kepez Yildiz Murat Hasanreisoglu Berati Hasanreisoglu 2015International Journal of Ophthalmology(English edition)2015,8,2:3
5Ultrasound biomicroscopic evaluation of anterior segment cysts as a risk factor for ocular hypertension and closure angle glaucoma显示文摘AIM:To investigate the relationship between the ultrasound biomicroscopic(UBM) features of anterior-segment cysts(ASCs) and increased intraocular pressure(IOP) as a risk factor for closed-angle glaucoma(CAG).·METHODS:Totally 24 eyes with recently diagnosed ASCs were divided into two groups.First group with ASC and ocular normotension(n =13),second group with ASC and ocular hypertension(n =11).An ophthalmologic examination,including tonometry,slit-lamp biomicro-scopy(SLBM),gonioscopy,fundoscopy,pentacam,and UBM,was performed.The features of the ASCs were compared with the IOP.·RESULTS:ASCs were accurately diagnosed and delineated in 24 eyes using UBM.IOP was elevated in those ASCs with a secondary aetiology(P =0.027),iridociliary location(P =0.006),deformed shape(P =0.013),increased size(P =0.001) and elongated pupillary aperture(P =0.009).However,the count(P =0.343) of ASCs,anterior chamber depth(ACD;P =0.22) and axial lenght(AL;P =0.31) were not associated with ocular hypertension.Correlations were found between the IOP and ASC size(r =-0.712;P =0.003),anterior chamber angle(ACA;r =-0.985;P <0.001),angle opening area(AOA;r =0.885;P<0.001),angulation of iris(r =-0.776,P <0.001),and affected iris quadrant(r =-0.655,P =0.002).·CONCLUSION:Ocular hypertension in some eyes with ASC might be associated with various mechanisms,including secondary aetiology,iridociliary location,deformed shape,increased size and elongated pupill,which can be determined by UBM.Abdurrahim Dusak Mehmet Baykara Guven Ozkaya Cuneyt Erdogan Hikmet Ozcetin Ercan Tuncel 2013International Journal of Ophthalmology(English edition)2013,6,4:3
6Laparoscopic right-sided colonic resection with transluminal colonoscopic specimen extraction显示文摘AIM: To study the transcolonic extraction of the proximally resected colonic specimens by colonoscopic assistance at laparoscopic colonic surgery. METHODS: The diagnoses of our patients were Crohn's disease, carcinoid of appendix and adenocarcinoma of cecum. We preferred laparoscopic total mesocolic resections. Colon and terminal ileum were divided with endoscopic staplers. A colonoscope was placed per anal and moved proximally in the colon till to reach the colonic closed end under the laparoscopic guidance. The stump of the colon was opened with laparoscopic scissors. A snare of colonoscope was released and the intraperitoneal complete free colonic specimen was grasped. Specimen was moved in to the colon with the help of the laparoscopic graspers and pulled gently through the large bowel and extracted through the anus. The open end of the colon was closed again and the ileal limb and the colon were anastomosed intracorporeally with a 60-mm laparoscopic stapler. The common enterotomy orifice was closed in two layers with a running intracorporeal suture.RESULTS: There were three patients with laparoscopic right-sided colonic resections and their specimens were intended to remove through the remnant colon by colonoscopy but the procedure failed in one patient(adenocarcinoma) due to a bulky mass and the specimen extraction was converted to transvaginal route. All the patients had prior abdominal surgeries and had related adhesions. The operating times were 210, 300 and 500 min. The lengths of the specimenswere 13, 17 and 27 cm. In our cases, there were no superficial or deep surgical site infections or any other complications. The patients were discharged uneventfully within 4-5 d and they were asymptomatic after a mean 7.6 mo follow-up(ranged 4-12). As far as we know, there were only 12 cases reported yet on transcolonic extraction of the proximal colonic specimens by colonoscopic assistance after laparoscopic resections. With our cases, success rate of the overall experience in the literature was 80%(12/15) in selected cases. CONCLUSION: Transcolonic specimen extraction for right-sided colonic resection is feasible in selected patients. Both natural orifice surgery and intracorporeal anastomosis avoids mini-laparotomy for specimen extraction or anastomosis.Cuneyt Kayaalp Koray Kutluturk Mehmet Ali Yagci Mustafa Ates 2015World Journal of Gastrointestinal Endoscopy2015,7,12:3
7土耳其西部新生代斑岩成矿岩浆氧逸度-挥发份元素组成演化特征--来自锆石和磷灰石组成约束显示文摘特提斯成矿域中段的土耳其西部集中产出了与俯冲、碰撞-后碰撞、伸展动力学背景有关的斑岩型铜、钼、金矿床。前人已完成了针对这些斑岩型矿床构造背景的大量研究工作,但对于区内不同构造背景下斑岩型矿床的成矿岩浆源区性质、成矿元素-挥发分含量和成矿物质演化关系尚未有系统研究。而这些研究将对认识中特提斯构造域晚白垩世以来在新特提斯洋俯冲、欧亚板块-Tauride-Anatolide板块碰撞和伸展过程中斑岩矿床形成时地壳厚度、壳幔相互作用方式及成矿物质演化过程具有重要意义。本研究选择土耳其西段三个斑岩成矿带(Tavşanl带、Biga半岛成矿带和Afyon-Konya带)内五个斑岩型矿床的成矿岩体与同期侵入岩-火山岩,开展锆石微量元素和磷灰石主量元素研究,限定碰撞与伸展环境下斑岩型矿床成矿岩浆的形成温度、氧逸度条件及其与岩浆形成时地壳厚度的关系,利用磷灰石F-Cl-S含量组成揭示熔体挥发分和硫元素的物质组成,进而约束新特提斯洋俯冲-碰撞-伸展过程中斑岩系统的深部物质演化规律。研究结果表明,土耳其西部新生代斑岩型矿床成矿岩浆锆石大部分落于高水含量-高氧逸度区间,具有相似的稀土元素标准化配分曲线。从始新世到中新世,锆石氧逸度Ce 4+/Ce 3+比值呈现出先降低(斑岩型Cu-Mo矿到斑岩型Mo矿)后升高(斑岩型Mo-Cu矿到斑岩Au矿)的趋势,且相对于斑岩型Mo矿和Mo-Cu矿,斑岩型Au矿和Cu-Mo矿成矿岩体的锆石形成时具有相对较高的氧逸度。绝大部分斑岩型矿床成矿岩体的锆石Eu N/Eu N*位于0.4~0.7之间,但斑岩型Mo矿和斑岩型Mo-Cu矿床的锆石具有相对较低的Eu N/Eu N*比值,可能是由于在结晶时熔体受斜长石结晶影响较大。锆石微量元素显示(Yb/Gd和Hf/Y-Th/U)锆石组成大部分受岩浆房中角闪石±榍石±磷灰石分离结晶控制。根据锆石Ti温度计估算土耳其西部斑岩型矿床成矿岩体及其相关岩体的形成温度在650~900℃之间,结晶温度从斑岩型Au矿、斑岩型Cu-Mo/Mo-Cu矿至斑岩型Mo矿呈现递减趋势。对于熔体的挥发分与硫含量组成,始新世-渐新世斑岩型Cu-Mo与Mo矿床成矿岩浆相对具有高F和低Cl组成,中新世伸展环境形成的斑岩型Mo-Cu矿和斑岩型Au矿床成矿岩浆Cl含量普遍较高。与成矿岩体同期的暗色包体或基性岩脉中磷灰石计算获得的熔体硫含量均大于侵入体对应熔体的硫含量,且具有不均一的含量组成,表明基性岩浆注入可能为岩浆房提供硫。结合区域动力学和地壳厚度估算,本文认为触发土耳其西部新生代斑岩矿床形成的动力学机制是:在新特提斯洋向北单向汇聚的背景下,北部始新世-渐新世斑岩矿床受控于碰撞后俯冲的新特提斯洋板片(Vardar洋)后撤-回转-断离过程;南部中新世斑岩矿床的形成则受控于爱琴海板片俯冲控制的地壳伸展-减薄过程。北侧Izmir-Ankara-Erzincan缝合带附近的Tavşanl与Biga半岛斑岩成矿带始新世-渐新世斑岩型矿床的形成与熔融-同化-储存-均一过程(MASH)有关,深部地壳热区过程(DCHZ)与中新世Afyon-Konya带斑岩型矿床的形成有关。赵俊兴 苏本勋 UYSAL I brahim AYDIN Faruk 肖燕 SEN Cuneyt 回凯旋 秦克章 2021岩石学报2021,37,8:2
8Renoportal anastomosis in living donor liver transplantation with prior proximal splenorenal shunt显示文摘For transplant surgeons, end-stage liver disease with portal venous thrombosis and a previous splenorenal shunt(SRS) is a significant challenge during liver transplantation. Thrombosis of the portal vein can be corrected by surgical interventions, such as portal venous thrombectomy or surgical removal of the thrombosed portal vein. Even also placement of a graft between the mesenteric vein and the graft portal vein can be performed. If these maneuvers fail, a renoportal anastomosis(RPA) can be performed to achieve adequate graft inflow. A 51-year-old male patient who had a history of proximal SRS and splenectomy underwent living donor liver transplantation(LDLT) due to cryptogenic cirrhosis. LDLT was performed with RPA using a cadaveric iliac vein graft. The early postoperative course of the patient was completely uneventful and he was discharged 20 d after transplantation. To the best of our knowledge, this was the first patient to receive LDLT with RPA after surgical proximal SRS and splenectomy.Fatih Ozdemir Koray Kutluturk Bora Barut Perviz Abbasov Ramazan Kutlu Cuneyt Kayaalp Sezai Y?lmaz 2017World Journal of Transplantation2017,7,1:2
9Outlier detection by means of robust regression estimators for use in engineering science显示文摘This study compares the ability of different robust regression estimators to detect and classify outliers. Well-known estimators with high breakdown points were compared using simulated data. Mean success rates (MSR) were computed and used as comparison criteria. The results showed that the least median of squares (LMS) and least trimmed squares (LTS) were the most successful methods for data that included leverage points, masking and swamping effects or critical and concentrated outliers. We recommend using LMS and LTS as diagnostic tools to classify outliers, because they remain robust even when applied to models that are heavily contaminated or that have a complicated structure of outliers.Serif HEKIMOGLU R. Cuneyt ERENOGLU Jan KALINA 2009Journal of Zhejiang University-Science A(Applied Physics & Engineering)2009,10,6:2
10Comparative study on volatile compounds in Turkish green tea powder: Impact of tea clone, shading level and shooting period显示文摘Ismail Tontul Mehmet Torun Cuneyt Dincer Hilal Sahin-Nadeem Ayhan Topuz Turgay Turna Feramuz Ozdemir 2012Food Research International2012,,:2
11Synthesis of biomimetic Ca hydroxyapatite powders at 37℃ in synthetic body fluids显示文摘Cuneyt Tas A 2000Biomaterials2000,21,14:1
12Transoral resection and reconstruction for primary osteogenic sarcoma of the second cervical vertebra显示文摘Cuneyt S Levent E 2001Spine2001,26,17:1
13Drill wear monitoring using cut-ting force signals显示文摘Ertunc H M Oysu Cuneyt 2004Mechatronics2004,14,:1
14Stability and Stabilizability of Discrete Event Dynamic Systems 显示文摘Cuneyt M 1991Journal of Association for Computing Machinery1991,38,3:1
15Acidic Leaching of Scheelite Concentrate and Production of Hetero-poly-tung- state Salt显示文摘Sebahattin G Servet T Cuneyt A 1999Hydrometallurgy1999,51,2:1
16EDLines: A real-time line segment detector with a false detection control显示文摘Cuneyt Akinlar Cihan Topal 2011Pattern Recognition Letters2011,,13:1
17Controlling massive hemorrhage from the retropancreatic portal vein as a complication of thromboendovenectomy during liver transplantation with balloon catheter tamponade: how to do it显示文摘Cemalettin Aydin Veysel Ersan Adil Baskiran Bulent Unal Cuneyt Kayaalp Sezai Yilmaz 2014Surgery Today2014,,4:1
18Correlation between metabolic syndrome and prostatic growth in benign prostatic hyperplasia显示文摘Cuneyt Ozden Ozdem Levent Ozdal Guvenc Urgancioglu 2010Eeuropean Urology2010,51,:1
19Tool wear con-dition monitoring using a sensor fusion mode based onfuzzy inference system显示文摘Cuneyt A Metin Ertunc H Hasan O 2009Mechanical Systems and Signal Processing2009,23,2:1
20An investigation of the chemical synthesis and high-temperature sintering behaviour of calcium hydroxyapatite (HA) and tricalcium phosphate (TCP) bioceramics显示文摘A CUNEYT TAS F KORKUSUZ M TIMUCIN N AKKAS 1997Journal of Materials Science: Materials in Medicine1997,,2:1
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