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| 1 | Low circulating levels of gastrin-17 in patients with Barrett's esophagus显示文摘AIM: To examine whether the fasting levels of serum gastrin-17 (G-17) are lower in Barrett's esophagus (BE)patients than in non-Barrett controls.METHODS: Nineteen patients with BE (presenting with a tubular segment ≥2 cm long in lower esophagus and intestinal metaplasia of incomplete type ('specialized columnar epithelium') in endoscopic biopsies from the tubular segment below the squamocolumnar junction were collected prospectively from outpatients referred to diagnostic gastroscopy. The controls comprised 199 prospectively collected dyspeptic outpatients without BE or any endoscopically visible lesions in the upper GI tract.Fasting levels of serum G-17 (G-17fast) were assayed with an EIA test using a Mab highly specific to amidated G-17. None of the patients and controls received therapy with PPIs or other antisecretory agents.RESULTS: The mean and median levels of G-17fast in serum were significantly lower (P = 0.001) in BE patients than in controls. The positive likelihood ratios (LR+) of low G-17fast to predict BE in the whole study population at G-17fast levels <0.5, <1, or <1.5 pmol/L were 3.5, 3.0,and 2.8, respectively. Among patients and controls with healthy stomach mucosa, the LR+ were 5.6, 3.8, and 2.6,respectively. In the whole study population, serum G-17 was below 2 pmol/L in 15 of 19 BE patients (79%). The corresponding prevalence was 66 of 199 (33%) in controls (P<0.001). The G-17fast was 5 pmol/L or more in only one of the 19 BE patients (5%). In controls, 76 of the 199 patients (38%) had such high serum G-17fast levels (P<0.01).CONCLUSION: Serum levels of G-17fast tend to be lower in native patients with BE than in healthy controls. | Pentti Sipponen Matti Vauhkonen Timo Helske Ilpo Kriinen Matti Hrknen | 2005 | World Journal of Gastroenterology2005，11，38： | 6 |
| 2 | CFD simulations of gas-solid flow in an industrial-scale circulating fluidized bed furnace using subgrid-scale drag models显示文摘Mesoscale flow structures such as clusters and streamers of particles are characteristic features of gas-solid flow in fluidized beds.Numerical simulations of gas-solid flows for industrial-scale fluidized beds are often performed using the Eulerian description of phases.An accurate prediction of this type of flow structure using the Eulerian modeling approach requires a sufficiently fine mesh resolution.Because of the long computational time required when using fine meshes,simulations of industrial-sized units are usually conducted using coarse meshes,which cannot resolve the mesoscale flow structures.This leads to an overestimation of the gas-solid drag force and a false prediction of the flow field.For these cases,a correction must be formulated for the gas-solid drag.We have simulated a large-scale circulating fluidized bed furnace using different gas-solid drag models and compared the model results with measurements. | Srujal Shah Kari My?h?nen Sirpa Kallio Timo Hypp?nen | 2015 | Particuology2015，13，1： | 4 |
| 3 | Rapid design and evaluation framework for wireless sensor networks显示文摘 | MAURI K MARKO H TIMO D H | 2008 | Ad Hoc Networks 62008，，4： | 1 |
| 4 | Surgical or Nonoperative Treatment for Lumbar Spinal Stenosis?: A Randomized Controlled Trial显示文摘 | Antti Malmivaara P?r Sl?tis Markku Heli?vaara P?ivi Sainio Heikki Kinnunen Jyrki Kankare Nina Dalin-Hirvonen Seppo Seitsalo Arto Herno Pirkko Kortekangas Timo Niinim?ki Hannu R?nty Kaj Tallroth Veli Turunen Paul Knekt Tommi H?rk?nen Heikki Hurri | 2007 | Spine2007，，1： | 1 |
| 5 | Rotation invariant im- age description with local binary pattern histogram Fourier features显示文摘 | Timo A Jiri M Chu H | 2009 | Lecture Notes in Computer Sci- ence2009，，5575： | 1 |
| 6 | Coarse woody debris in a montane forest in Ecuador: mass, C and nutrient stock, and turnover 显示文摘 | Wolfgang W Timo H Christoph B | 2005 | Forest Ecology and Management2005，205，1： | 1 |
| 7 | Synthesis and structure- activity relationship in a class of indolebutylpiperazines as dual 5-HT1A receptor agonists and serotonin reuptake inhibitors 显示文摘 | Timo H Henning B Rolf G | 2004 | JMed Chem2004，47，19： | 1 |
| 8 | Functional and structual regression of the rabbit corpus luteum is associated with altered luteal immune cell phenotypes and cytokine expression patterns 显示文摘 | Claudia A K Timo D V Andreas H | 2002 | Histochemistry and Cell Biology2002，118，6： | 1 |
| 9 | Space aver- aging on a gas-solid drag model for numerical simula- tions of a CFB riser 显示文摘 | SRUJAL S JOUNI R TIMO H | 2012 | Powder Technology2012，218，： | 1 |
| 10 | UV spectrophotometric determination of lignin from alkaline pulping liquors显示文摘 | Raimo A Timo H | | 0，，： | 1 |
| 11 | Cardiovascular autonomic function correlates with the response to aerobic training in healthy sedentary subjects 显示文摘 | Hautala Arto J Timo H | 2003 | Am J Physiol Heart Circ Physiol2003，285，： | 1 |
| 12 | Use of a virtual 3D software of tibial plateau fracture reconstruction显示文摘 | Eduardo MS Tobias H Timo S | 2010 | Injury2010，41，6： | 1 |
| 13 | Structures sensory activity, and dose/response functions of 2,5-diketopiperazines in roasted Cocoa nibs( Theobroma cacao) 显示文摘 | TIMO S THOMAS H | 2005 | Agric Food Chem2005，53，： | 1 |
| 14 | Synthesis and structure- activity relationship in a class of indolebutylpiperacines as dual- 5-HTIA receptor agonists and sero tonin reuptake inhibitors 显示文摘 | TIMO H HENNING B ROLF G | 2004 | J Med Chem2004，47，19： | 1 |
| 15 | A joint finite mixture model for clustering genes from independent Gaussian and beta distributed data 显示文摘 | Xiao Feng D Timo E OUi Y H | 2009 | BMC Bioinformatics2009，10，： | 1 |
| 16 | Prevention of virus persistenceand protection against immunopathology after Borna disease virus in-fection of the brain by a novel Orf virus recombinant显示文摘 | Marco H Oliver P Timo F | 2005 | J Virol2005，79，1： | 1 |
| 17 | Field programmable gate array-based PCI interface for a coprocessor system显示文摘 | KIMMO K TIMO H JUKKA S | 1999 | Micoprocessors and Mierosystems1999，22，7： | 1 |
| 18 | Antiviral terpenoid constituents of ganoderma pfeifferi 显示文摘 | Timo H J NiedermeyerU L | 2005 | J Nat Prod2005，68，： | 1 |
| 19 | Quantifying Inflation Expectations with the Carlson- Parkin Method: A Survey- based De- termination of the Just Noticeable Difference 显示文摘 | STEFFEN H AND TIMO W | 2005 | Journal of Business Cycle Measurement and Analysis2005，，3： | 1 |
| 20 | A comparative study of texture mea- sures with classification based on featured distributions 显示文摘 | TIMO O MATTI P DAVID H | 1996 | Pattern Recognition1996，29，1： | 1 |
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