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| 1 | Faecalibacterium prausnitzii and human intestinal health显示文摘 | S Miquel R Martín O Rossi LG Bermúdez-Humarán JM Chatel H Sokol M Thomas JM Wells P Langella | 2013 | Current Opinion in Microbiology2013，，： | 3 |
| 2 | 糖尿病性视网膜病显示文摘据估计,每年因视网膜病而失明的糖尿病人在美国有5千人而全世界有3万~4万人。自1974年以来,在大不列颠、北美、欧洲和斯堪的纳维亚等地区,虽然光凝术和玻璃体切割术的应用取得进展,但糖尿病性视网膜病仍为致盲的主要原因。 尽管对糖尿病性视网膜病的病因还不甚了解,但视网膜的解剖学改变已相当明确,包括内皮细胞增生,毛细血管闭塞和网膜前新生血管形成等特征。 | Thomas JM 徐燕琳 | 1991 | 国际内分泌代谢杂志1991，25，4： | 2 |
| 3 | Geneticmodification of liver grafts with an adenoviral vector encoding the Bcl-2 geneimproves organ preservation显示文摘 | Bilbao G Contreras JL Gomez Navarro J Eckhoff DE Mikheeva G Krasnykh V Hynes T Thomas FT Thomas JM Curiel DT | | 0，，： | 2 |
| 4 | Interferon-γ inhibits ghrelin expression and secretion via a somatostatin-mediated mechanism显示文摘AIM:To investigate if and how the proinflammatory cytokine interferon γ(IFNγ) affects ghrelin expression in mice.METHODS:The plasma concentration of ghrelin,andgastric ghrelin and somatostatin expression,were examined in wild-type mice and mice infected with Helicobacter pylori(H.pylori).Furthermore,ghrelin expression was examined in two achlorhydric mouse models with varying degrees of gastritis due to bacterial overgrowth.To study the effect of IFNγ alone,mice were given a subcutaneous infusion of IFNγ for 7 d.Finally,the influence of IFNγ and somatostatin on the ghrelin promoter was characterized.RESULTS:H.pylori infection was associated with a 50% reduction in ghrelin expression and plasma concentration.Suppression of ghrelin expression was inversely correlated with gastric inflammation in achlorhdyric mouse models.Subcutaneous infusion of IFNγ suppressed fundic ghrelin mRNA expression and plasma ghrelin concentrations.Finally,we showed that the ghrelin promoter operates under the control of somatostatin but not under that of IFNγ.CONCLUSION:Gastric infection and inflammation is associated with increased IFNγ expression and reduced ghrelin expression.IFNγ does not directly control ghrelin expression but inhibits it indirectly via somatostatin. | Jesper AB Strickertsson Kristina BV DΦssing Anna JM Aabakke Hans-Olof Nilsson Thomas VO Hansen Ulrich Knigge Andreas Kjr Torkel Wadstrm Lennart Friis-Hansen | 2011 | World Journal of Gastroenterology2011，17，26： | 2 |
| 5 | The wilson disease gene is a putative copper transporting P- type ATPase similar to the Menkes gene 显示文摘 | Thomas GR Rommens JM | 1993 | Nature Genet1993，5，12： | 1 |
| 6 | Excision margins in high-risk malignant melanoma 显示文摘 | Thomas JM Newton-Bishop J A'Hem R | 2004 | New Engl J Med2004，350，8： | 1 |
| 7 | Imaging features of aggressive angiomyxoma 显示文摘 | Jeyadevan NN Sohaib SA Thomas JM | 2003 | Clin Radiol2003，58，2： | 1 |
| 8 | Application of tumour markers in clinical practice 显示文摘 | Keuren JF Thomas CM Bonfrer JM | 2009 | Ned Tijdschr Geneeskd2009，153，： | 1 |
| 9 | Free and total magnesium in lymphocytes of migraine patients-effect of magnesium-rich mineral water intake显示文摘 | Thomas J Millot JM Sebille S | 2000 | Clin Chim Acta2000，29，5： | 1 |
| 10 | Inciden mortality and survival in cutaneous melanoma 显示文摘 | Giblin AV Thomas JM | 2007 | J Plast Reconstr Aesthet Surg2007，60，1： | 1 |
| 11 | The management of retroperitoneal soft tissue sarcomas显示文摘 | Jenkins MP Alvaranga JC Thomas JM | 1996 | Eur J Cancer1996，32，4： | 1 |
| 12 | A breaker of advanced glycation end products attenuates diabetes-induced myocardial structural changes显示文摘 | Candido R Forbes JM Thomas MC | 2003 | Circ Res2003，92，4： | 1 |
| 13 | Aggressive angiomyxoma:a distinct clinical entity显示文摘 | Behranwala KA Thomas JM | 2003 | Eur J Surg Oncol2003，29，7： | 1 |
| 14 | Acidic libroblast growth factor stimulates motor and sensory axon regeneration after sciatic nerve crush in the rat显示文摘 | Laird JM Mason GS Thomas KA Hargreaves RJ Hill RG | 1995 | Neuroscience1995，65，1： | 1 |
| 15 | The Wilson disease geneis a putative copper transporting P-type ATPase similar to theMenkes gene显示文摘 | Bull PC Thomas GR Rommens JM | 1993 | Nature Gene1993，5，12： | 1 |
| 16 | Outcome of treatment in adults with acute lympoblastic leukemia:Analysis of the LALA-94 trial 显示文摘 | Thomas X Boiron JM Huguet F | 2004 | J Clin Oncol2004，22，： | 1 |
| 17 | Treatment for breast sarcoma:a large,single-centre series显示文摘 | Pencavel T Allan CP Thomas JM | 2011 | Eur J Surg Oncol2011，37，8： | 1 |
| 18 | Patients assessment of outcome after three surgical procedures for the management of trigeminal neuralgia显示文摘 | Zakrzewska JM Thomas DG | 1993 | Acta Neurochir (Wien)1993，122，34： | 1 |
| 19 | Murine allergic respiratory responses to the major house dust mite allergen Der p 1 显示文摘 | Clarke AH Thomas WR Rolland JM Dow C O'Brien RM | 1999 | lnt Arch Allergy Immunol1999，120，2： | 1 |
| 20 | Imaging features of aggressive angiomyxoma显示文摘 | Jeyadevan NN Sohaib SA Thomas JM | 2003 | Clin Radiol2003，58，2： | 1 |
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