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| 1 | Blood glucose changes surrounding initiation of tumor-necrosis factor inhibitors and conventional disease-modifying anti-rheumatic drugs in veterans with rheumatoid arthritis显示文摘AIM To determine the scope of acute hypoglycemic effects for certain anti-rheumatic medications in a large retrospective observational study. METHODS Patients enrolled in the Veterans Affairs Rheumatoid Arthritis (VARA) registry were selected who, during follow-up, initiated treatment with tumor necrosis factor inhibitors (TNFi's, including etanercept, adalimumab, infliximab, golimumab, or certolizumab), prednisone, or conventional disease-modifying anti-rheumatic drugs(DMARDs), and for whom proximate random blood glucose (RBG) measurements were available within a window 2-wk prior to, and 6 mo following, medication initiation. Similar data were obtained for patients with proximate values available for glycosylated hemoglobin A1C values within a window 2 mo preceding, and 12 mo following, medication initiation. RBG and A1C measurements were compared before and after initiation events using paired t-tests, and multivariate regression analysis was performed including established comorbidities and demographics.RESULTS Two thousands one hundred and eleven patients contributed at least one proximate measurement surrounding the initiation of any examined medication. A significant decrease in RBG was noted surrounding 653 individual hydroxychloroquine-initiation events(-3.68 mg/dL, P = 0.04), while an increase was noted for RBG surrounding 665 prednisone-initiation events(+5.85 mg/d L, P < 0.01). A statistically significant decrease in A1C was noted for sulfasalazine initiation, as measured by 49 individual initiation events(-0.70%, P < 0.01). Multivariate regression analyses, using methotrexate as the referent, suggest sulfasalazine (β =-0.58, P = 0.01) and hydroxychloroquine(β =-5.78, P = 0.01) use as predictors of lower post-medicationinitiation RBG and A1C values, respectively. Analysis by drug class suggested prednisone (or glucocorticoids) as predictive of higher medication-initiation event RBG among all start events as compared to DMARDs, while this analysis did not show any drug class-level effect for TNFi. A diagnosis of congestive heart failure(β = 4.69, P = 0.03) was predictive for higher post-initiation RBG values among all medication-initiation events.CONCLUSION No statistically significant hypoglycemic effects surrounding TNFi initiation were observed in this large cohort. Sulfasalazine and hydroxychloroquine may have epidemiologically significant acute hypoglycemic effects. | Patrick R Wood Evan Manning Joshua F Baker Bryant England Lisa Davis Grant W Cannon Ted R Mikuls Liron Caplan | 2018 | World Journal of Diabetes2018，9，2： | 8 |
| 2 | Ignition and combustion of aluminum/mag nesium alloy particles in O2 at high pressures显示文摘 | Ted A R Rodney L B | | Combustion and Flame0，92，： | 2 |
| 3 | Coronary artery bypass graft surgery versus percutaneous coronary intervention in patients with three-vessel disease and left main coronary disease: 5-year follow-up of the randomised, clinical SYNTAX trial显示文摘 | Friedrich W Mohr Marie-Claude Morice A Pieter Kappetein Ted E Feldman Elisabeth St?hle Antonio Colombo Michael J Mack David R Holmes Marie-angèle Morel Nic Van Dyck Vicki M Houle Keith D Dawkins Patrick W Serruys | 2013 | The Lancet . 2013 (9867)2013，，9867： | 2 |
| 4 | Dental and facial skeletal characteristicsand growth of males and females with class II division 1 maloc-clusion between the age of 10 and 14-part I: characteristics ofsize,form and position 显示文摘 | Ted R Yoon-Tarlie L | 2000 | Am J Orthod Dentofac Orthop2000，117，3： | 1 |
| 5 | Bile Acids Induce Glucagon-Like Peptide 2 Secretion with Limited Effects on Intestinal Adaptation in Early Weaned Pigs显示文摘 | Ipharraguerre I R TedóG Menoyo D | 2013 | J Nutr2013，143，12： | 1 |
| 6 | A Multifeature Decision Space Approach to Radar Target Identifiea- tion显示文摘 | Ted J G Gorman R P Berger W A | 1996 | IEEE Trans on Aerospace and Electronic Sys*ems1996，32，1： | 1 |
| 7 | Capsaicin displays anti-proliferative activity against human small cell lung cancer in cell culture and nude mice models via the E2F pathway显示文摘 | KATHLEEN C BROWN TED R | 2010 | PLoS One2010，5，10： | 1 |
| 8 | How safe are our schools显示文摘 | Ted R Miller RS | 1998 | Am J Public Heaith1998，88，： | 1 |
| 9 | Coronary artery bypass graft surgery versus percutaneous coronary intervention in patients with three-vessel disease and left main coronary disease: 5-year follow-up of the randomised, clinical SYNTAX trial显示文摘 | Friedrich W Mohr Marie-Claude Morice A Pieter Kappetein Ted E Feldman Elisabeth St?hle Antonio Colombo Michael J Mack David R Holmes Marie-angèle Morel Nic Van Dyck Vicki M Houle Keith D Dawkins Patrick W Serruys | 2013 | The Lancet2013，，9867： | 1 |
| 10 | Inversion for refractivity parameters from radar sea clutter显示文摘 | GERSTOFT P TED R JEFFREY L K | 2003 | Radio Sci2003，32，2： | 1 |
| 11 | Sclerosing lymphangitis of the pe, nis显示文摘 | Ted R Heidi H | 2003 | J Am Aead Dermatol2003，49，5： | 1 |
| 12 | Periedontitis and porphyrmonas gingivalis in patients with rheumatoid arthritis显示文摘 | Ted R Mikuls Jeffrey B Payne Fang Yu | 2014 | Published in final edited form as: Arthritis Rheumatol2014，66，5： | 1 |
| 13 | Ignition and combustion of aluminum/magnesium alloy particles in O2 at high pressures显示文摘 | Ted A R Rodney L B | 1993 | Combustion and Flame1993，92，： | 1 |
| 14 | Sclerosing lymphangitis of the penis显示文摘 | Ted R Heidi H | 2003 | J Am Acad Dermatol2003，49，5： | 1 |
| 15 | Coronary artery bypass graft surgery versus percutaneous coronary intervention in patients with three-vessel disease and left main coronary disease: 5-year follow-up of the randomised, clinical SYNTAX trial显示文摘 | Friedrich W Mohr Marie-Claude Morice A Pieter Kappetein Ted E Feldman Elisabeth St?hle Antonio Colombo Michael J Mack David R Holmes Marie-angèle Morel Nic Van Dyck Vicki M Houle Keith D Dawkins Patrick W Serruys | 2013 | The Lancet2013，，9867： | 1 |
| 16 | Anatomical and clinical characteristics to guide decision making between coronary artery bypass surgery and percutaneous coronary intervention for individual patients: development and validation of SYNTAX score II显示文摘 | Vasim Farooq David van Klaveren Ewout W Steyerberg Emanuele Meliga Yvonne Vergouwe Alaide Chieffo Arie Pieter Kappetein Antonio Colombo David R Holmes Michael Mack Ted Feldman Marie-Claude Morice Elisabeth St?hle Yoshinobu Onuma Marie-angèle Morel Hector | 2013 | The Lancet2013，，9867： | 1 |
| 17 | Is New Urbanism the Cure?A Look at Central Florida's Response显示文摘 | Brown Ted R Bonifay Cecelia | 2001 | Real Estate Issues2001，26，3： | 1 |
| 18 | Inversion for refractivity parameters from radar sea clutter显示文摘 | PETER G TED R JEFFREY L K | 2003 | Radio Sci2003，32，2： | 1 |
| 19 | Modeling and testing a salt gradient solar pond in Northeast Ohio显示文摘 | S Shah H Ted R Peter | 1981 | Solar Energy1981，27，： | 1 |
| 20 | Characterization of a DNA vaccine expressing a human immunodeficiency virus-like particle 显示文摘 | Kelly R Y James M S Ted M R | 2004 | Virology2004，327，： | 1 |
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