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| 1 | study to determine guidelines for pediatric colonoscopy显示文摘AIM To investigated characteristics, diagnosis, bowelcleansing preparation, sedation, and colonoscope length and diameter in Japanese pediatric patients receiving total colonoscopy.METHODS The present study evaluated consecutive patients aged ≤ 15 years who had undergone their first colonoscopy in Kurume University between January 2007 and February 2015. Data were retrospectively analyzed. We identified 110 pediatric patients who had undergone colonoscopy that had reached the cecum, allowing the observation of the total colon.RESULTS Hematochezia, abdominal pain, and diarrhea were the most common symptoms. For bowel-cleansing preparation, pediatric patients aged ≤ 12 years were treated with magnesium citrate, and patients aged 13-15 years were treated with polyethylene glycol 4000. For sedation, thiamylal with pentazocine, which has an analgesic effect, was used in patients aged ≤ 6 years, and midazolam with pentazocine was used in patients aged ≥ 7 years. Regarding the choice of endoscope, short and thin endoscopes were selected for younger patients, particularly patients aged ≤ 3 years. Positive diagnoses were made in 78 patients(70.9%). Inflammatory bowel disease(n = 49, 44.5%), including ulcerative colitis(n = 37, 33.6%) and Crohn's disease(n = 12, 10.9%), was the most common diagnosis. CONCLUSION Colonoscopy offers a high diagnostic capability for pediatric patients with gastrointestinal symptoms. The selection of appropriate management the performance of colonoscopy is important in pediatric patients. | Shinichiro Yoshioka Hidetoshi Takedatsu Shuhei Fukunaga Kotaro Kuwaki Hiroshi Yamasaki RyosukeYamauchi Atsushi Mori Hiroshi Kawano Tadahiro Yanagi Tatsuki Mizuochi Kosuke Ushijima Keiichi Mitsuyama Osamu Tsuruta Takuji Torimura | 2017 | World Journal of Gastroenterology2017,23,31: | 10 |
| 2 | Serum magnesium concentration in children with functional constipation treated with magnesium oxide显示文摘AIM:To determine whether hypermagnesemia recently reported in adult patients possibly develops in children with functional constipation taking daily magnesium oxide.METHODS:We enrolled 120 patients (57 male and 63 female) aged 1-14 years old (median:4.7 years) with functional constipation from 13 hospitals and two private clinics.All patients fulfilled the Rome Ⅲ criteria for functional constipation and were treated with daily oral magnesium oxide for at least 1 mo.The median treatment dose was 600 (500-800) mg/d.Patients were assessed by an interview and laboratory examination to determine possible hypermagnesemia.Serum magnesium concentration was also measured in sex-and agematched control subjects (n=38).RESULTS:In the constipation group,serum magnesium concentration [2.4 (2.3-2.5) mg/dL,median and interquartile range] was significantly greater than that of the control group [2.2 (2.0-2.2) mg/dL] (P < 0.001).The highest value was 3.2 mg/dL.Renal magnesium clearance was significantly increased in the constipation group.Serum magnesium concentration in the constipation group decreased significantly with age (P < 0.01).There was no significant correlation between the serum level of magnesium and the duration of treatment with magnesium oxide or the daily dose.None of the patients had side effects associated with hypermagnesemia.CONCLUSION:Serum magnesium concentration increased significantly,but not critically,after daily treatment with magnesium oxide in constipated children with normal renal function. | Maiko Tatsuki Reiko Miyazawa Takeshi Tomomasa Takashi Ishige Tomoko Nakazawa Hirokazu Arakawa | 2011 | World Journal of Gastroenterology2011,17,6: | 4 |
| 3 | Significance of serum and hepatic micro RNA ‐122 levels in patients with non‐alcoholic fatty liver disease显示文摘 | Hisamitsu Miyaaki Tatsuki Ichikawa Yasuhiro Kamo Naota Taura Takuya Honda Hidetaka Shibata Maddalena Milazzo Francesca Fornari Laura Gramantieri Luigi Bolondi Kazuhiko Nakao | 2014 | Liver Int2014,,7: | 4 |
| 4 | 冷冻-干燥工艺合成复合孔结构的多孔陶瓷显示文摘冷冻-干燥工艺合成了复合孔结构的多孔陶瓷。控制冰的生长方向的同时完成水基陶瓷浆料的冻结。在低压下干燥使冰由固态到气态而升华。烧成后的坯体为具有复合孔结构的多孔陶瓷:肉眼可见的大孔整齐排列,大孔内壁还含有显微孔。从本质上讲,孔结构是受起始浆料浓度及烧成温度的影响的。本文还讨论了在这些因素影响下孔的形成机理。 | Takayuki Fukasawa Motohide Ando Tatsuki Ohji Shuzo Kanzaki 张玉珍 | 2001 | 江苏陶瓷2001,34,3: | 2 |
| 5 | Clinical characteristics of hepatocellular carcinoma in elderly patients显示文摘 | Takuya Honda Hisamitsu Miyaaki Tatsuki Ichikawa Naota Taura Satoshi Miuma Hidetaka Shibata Hajime Isomoto Fuminao Takeshima Kazuhiko Nakao | 2011 | Oncology Letters2011,,5: | 2 |
| 6 | Novel serine/threonine kinase 11 gene mutations in PeutzJeghers syndrome patients and endoscopic management显示文摘AIM:To explore mutations in serine/threonine kinase 11(STK11) gene in Peutz-Jeghers syndrome(PJS) with gastrointestinal(GI) hamartomatous polyps.METHODS:Six Japanese PJS patients in 3 families were enrolled in this study.Each of the cases had hamartomatous polyposis in the gastrointestinal tract,including the small intestine,along with mucocutaneous hyperpigmentation.Narrow-band imaging(NBI)-magnification endoscopy was employed to detect microvascular and microsurface irregularities in the GI lesions.NBI magnification findings could be classified into three groups(type A,type B,or type C).Endoscopic polypectomy was performed using double-balloon enteroscopy or colonoscopy.Genomic DNA was extracted from a whole blood sample from each subject.All of the coding exons of STK11 gene,its boundary regions,and the promoter region containing the polymorphic regions were amplified by polymerase chain reaction,and direct sequencing was performed to assess the germline mutations.RESULTS:NBI-magnification endoscopic observation could detect the abnormalities in microvessels and microsurface structures of GI polyps.Overall,we found 5 cases of type A and one case without the examination for the gastric polyps,while there were 4 cases of type B and 2 case of type A for the colorectal polyps.Seventy-nine small-bowel and 115 colorectal polyps over 27 sessions for each were resected endoscopically without significant complications.The only delayed complication included the occurrence of bleeding in a case,and this was successfully managed with hemoclips.Resected polyps contained no malignant components.Based on mutation analysis,all 3 cases in Family I exhibited the +658C>T nonsense mutation in exon 5,which resulted in the production of a truncated protein(Q220X).In Family II,a case had-252C>A and-193C>A in the promoter region.In Family III,a case was found to have the +1062C>G(F342L) mutation in exon 8.CONCLUSION:We found two novel mutations of STK11 in association with PJS.Endoscopic polypectomy of GI polyps in PJS patients appears to be useful to prevent emergency laparotomies and reduce the cancer risk. | Hiroyuki Yajima Hajime Isomoto Hiroaki Nishioka Naoyuki Yamaguchi Ken Ohnita Tatsuki Ichikawa Fuminao Takeshima Saburo Shikuwa Masahiro Ito Kazuhiko Nakao Kazuhiro Tsukamoto Shigeru Kohno | 2013 | World Journal of Gastrointestinal Endoscopy2013,5,3: | 2 |
| 7 | Domestic wastewater treatment by a submerged membrane bioreactor with gravitational filtration显示文摘 | Tatsuki Ueda Kenji Hata | 1999 | Water Research1999,,12: | 2 |
| 8 | A snack enriched with oral branched-chain amino acids prevents a fall in albumin in patients with liver cirrhosis undergoing chemoembolization for hepatocellular carcinoma显示文摘 | Shigeyuki Takeshita Tatsuki Ichikawa Kazuhiko Nakao Hisamitsu Miyaaki Hidetaka Shibata Toshihisa Matsuzaki Toru Muraoka Takuya Honda Masashi Otani Motohisa Akiyama Satoshi Miuma Esuke Ozawa Masumi Fujimito Katsumi Eguchi | 2009 | Nutrition Research2009,,2: | 2 |
| 9 | High-Pressure Synthesis and Superconductivity of Sr-Ca-Cu-O-Cl Compounds with 0212-Type and 0223-Type Structure显示文摘 | Tatsuki T Adachi S Tamura T | 1998 | Physica C1998,306,: | 1 |
| 10 | Postmarketing surveillanceof the safety profile of infliximab in 5000 Japanese patients withrheumatoid arthritis 显示文摘 | Takeuchi T Tatsuki Y Nogami Y | 2008 | Ann Rheum Dis2008,67,2: | 1 |
| 11 | Reinforcement by crack-tip blunting in porous ceramics显示文摘 | Zhen-Yan Deng Jihong She Yoshiaki Inagaki Jian-Feng Yang Tatsuki Ohji Yoshihisa Tanaka | 2003 | Journal of the European Ceramic Society2003,,7: | 1 |
| 12 | Anti-tumor effect in human breast cancer by TAE226, a dual inhibitor for FAK and IGF-IR in vitro and in vivo显示文摘 | Naito Kurio Tsuyoshi Shimo Takuya Fukazawa Munenori Takaoka Tatsuo Okui Nur Mohammad Monsur Hassan Tatsuki Honami Shinji Hatakeyama Masahiko Ikeda Yoshio Naomoto Akira Sasaki | 2011 | Experimental Cell Research2011,,: | 1 |
| 13 | The effect of the plant host to subspecies differentiating in rice and water-oats-population of stem borer显示文摘 | Tatsuki S | 2001 | Otoshibumi2001,21,: | 1 |
| 14 | The involvement of 1 -aminocyclopropane- 1 -carboxylic acid synthase isogene, Pp-ACSI, in peach fruit softening显示文摘 | Tatsuki M Haji T Masami Y | 2006 | J Exp Bot2006,,57: | 1 |
| 15 | Verification Tests and Insulation Design Method of Cold Dielectric Superconducting Cable 显示文摘 | Hiroshi Suzuki Toshihiro Takahashi Tatsuki Okamoto | 2008 | Electrical Engineering in Japan2008,164,2: | 1 |
| 16 | Structures of sex pheromones of rice stem borer显示文摘 | Ohta K Tatsuki T Uchiuml K | 1976 | Agricultural and Biological Chemistry1976,40,9: | 1 |
| 17 | The involvement of 1-aminocyclopropane-l-carboxylic acid synthase isogene,Pp-ACS1,in peach fruit softening显示文摘 | TATSUKI M HAJI T YAMAGUCHI M | 2006 | Journal of Experimental Botany2006,57,: | 1 |
| 18 | Apple ethylene receptor protein concentrations are affected by ethylene, and in cuhivars that have different storage life显示文摘 | Tatsuki M Hayama H Nakamur Y | 2009 | Planta2009,230,: | 1 |
| 19 | Ethylene and fruit softening in the stony hard mutation in peach显示文摘 | HAYAMA H TATSUKI M ITO A | 2006 | Postharvest Biology and Technology2006,41,: | 1 |
| 20 | Branched‐chain amino acid deficiency stabilizes insulin‐induced vascular endothelial growth factor mRNA in hepatocellular carcinoma cells显示文摘 | Satoshi Miuma Tatsuki Ichikawa Kazuhiko Arima Shigeyuki Takeshita Toru Muraoka Toshihisa Matsuzaki Masashi Ootani Hidetaka Shibata Motohisa Akiyama Eisuke Ozawa Hisamitsu Miyaaki Naota Taura Fuminao Takeshima Kazuhiko Nakao | 2012 | J Cell Biochem2012,,10: | 1 |