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| 1 | 强制运动促进成年大鼠海马齿状回神经发生并提高学习能力(英文)显示文摘为了探讨强制运动对成年大鼠海马齿状回(dentategyrus,DG)神经发生的影响,强制大鼠在马达驱动的转轮中跑步,用5-溴-2-脱氧尿苷(5-bromo-2-deoxyuridine,BrdU)标记增殖细胞,巢蛋白(neuroepthelialstemcellprotein,nestin)标记神经干细胞/前体细胞,然后用免疫细胞化学技术检测大鼠DG中BrdU及nestin阳性细胞。为了解强制运动后DG增殖细胞的功能意义,采用Y-迷宫检测大鼠的学习能力。结果表明,强制运动组DG中BrdU及nestin阳性细胞数均明显多于对照组(P<0.05);强制运动对DG神经发生的效应有强度依赖性。Y-迷宫检测结果显示,强制运动能明显改善大鼠的学习能力。结果提示,在转轮中进行强制跑步能促进成年大鼠DG的神经发生,并改善学习能力。 | 徐卫平 单立冬 龚珊 陈琳 张跃进 印其章 HISAMITSU Tadashi 蒋星红 郭试瑜 | 2006 | 生理学报2006，58，5： | 18 |
| 2 | Effects of exercise on neurogenesis in the dentate gyrus and ability of learning and memory after hippocampus lesion in adult rats显示文摘Objective To explore the effects of exercise on dentate gyrus (DG) neurogenesis and the ability of learning and memory in hippocampus-lesioned adult rats. Methods Hippocampus lesion was produced by intrahippocampal microinjection of kainic acid (KA). Bromodeoxyuridine (BrdU) was used to label dividing cells. Y maze test was used to evaluate the ability of learning and memory. Exercise was conducted in the form of forced running in a motor-driven running wheel. The speed of wheel revolution was regulated at 3 kinds of intensity: lightly running, moderately running, or heavily running. Results Hippocampus lesion could increase the number of BrdU-labeled DG cells, moderately running after lesion could further enhance the number of BrdU-labeled cells and decrease the error number (EN) in Y maze test, while neither lightly running, nor heavily running had such effects. There was a negative correlation between the number of DG BrdU-labeled cells and the EN in the Y maze test after running. Conclusion Moderate exercise could enhance the DG neurogenesis and ameliorate the ability of learning and memory in hippocampus-lesioned rats. | Lin CHEN Shan GONG Li-Dong SHAN Wei-Ping XU Yue-Jin ZHANG Shi-Yu GUO Tadashi Hisamitsu Qi-Zhang YIN Xing-Hong JIANG | 2006 | Neuroscience Bulletin2006，22，1： | 11 |
| 3 | Significance of serum and hepatic micro RNA ‐122 levels in patients with non‐alcoholic fatty liver disease显示文摘 | Hisamitsu Miyaaki Tatsuki Ichikawa Yasuhiro Kamo Naota Taura Takuya Honda Hidetaka Shibata Maddalena Milazzo Francesca Fornari Laura Gramantieri Luigi Bolondi Kazuhiko Nakao | 2014 | Liver Int2014，，7： | 4 |
| 4 | Clinical characteristics of hepatocellular carcinoma in elderly patients显示文摘 | Takuya Honda Hisamitsu Miyaaki Tatsuki Ichikawa Naota Taura Satoshi Miuma Hidetaka Shibata Hajime Isomoto Fuminao Takeshima Kazuhiko Nakao | 2011 | Oncology Letters2011，，5： | 2 |
| 5 | A snack enriched with oral branched-chain amino acids prevents a fall in albumin in patients with liver cirrhosis undergoing chemoembolization for hepatocellular carcinoma显示文摘 | Shigeyuki Takeshita Tatsuki Ichikawa Kazuhiko Nakao Hisamitsu Miyaaki Hidetaka Shibata Toshihisa Matsuzaki Toru Muraoka Takuya Honda Masashi Otani Motohisa Akiyama Satoshi Miuma Esuke Ozawa Masumi Fujimito Katsumi Eguchi | 2009 | Nutrition Research2009，，2： | 2 |
| 6 | Modulation of Th2 type cytodinproduction from human peripheral blood leukocytes by a macrolide antibioltisroxithromycin,in vitro显示文摘 | Asano K Kamakazu K Hisamitsu T | | 0，，： | 1 |
| 7 | The efficacy of dentine adhesive to sclerotic dentine显示文摘 | Kusunoki M Itoh K Hisamitsu H | 2002 | J Dent2002，30，3： | 1 |
| 8 | In vitro anti-mutagenic effect of magnolol against direct and indirect mutagens 显示文摘 | JUNICHIRO S YOSH1MICHI S HISAMITSU N | 2006 | Mut Res2006，609，1： | 1 |
| 9 | Effect of the incorporation of amino groups in a glucose-responsive polymer complex having phenylborenic acid moieties 显示文摘 | Shigeru Kitano Issei Hisamitsu Yoshiyuki Koyama Kazunori Kataoka | 1991 | Polymers for Advanced Technologies1991，2，： | 1 |
| 10 | In vitro inhibition of caries around a resin composite restoration containing antibacterial filler 显示文摘 | Syafiuddin T Hisamitsu H Toko T | 1997 | Biomaterials1997，18，15： | 1 |
| 11 | Branched‐chain amino acid deficiency stabilizes insulin‐induced vascular endothelial growth factor mRNA in hepatocellular carcinoma cells显示文摘 | Satoshi Miuma Tatsuki Ichikawa Kazuhiko Arima Shigeyuki Takeshita Toru Muraoka Toshihisa Matsuzaki Masashi Ootani Hidetaka Shibata Motohisa Akiyama Eisuke Ozawa Hisamitsu Miyaaki Naota Taura Fuminao Takeshima Kazuhiko Nakao | 2012 | J Cell Biochem2012，，10： | 1 |
| 12 | Shear bond strength of composite resin to unbleached and bleached human dentine显示文摘 | Toko T Hisamitsu H | 1993 | Asian J Aesthet Dent1993，1，1： | 1 |
| 13 | Prevalence of type 2 diabetes mellitus in Japanese patients with hepatocellularcarcinoma显示文摘 | Naota Taura Tatsuki Ichikawa Hisamitsu Miyaaki Hiroshi Yatsuhashi Hiromi Ishibashi Kazuhiko Nakao | 2011 | Experimental and Therapeutic Medicine2011，，1： | 1 |
| 14 | Functional importance of charged residues within the putative intracellular loops in pH regulation by Na+/H+exchanger NHE1显示文摘 | Hisamitsu T Yamada K Nakamura T Y | 2007 | FEBS J2007，274，16： | 1 |
| 15 | Functional importance of charged residues within the putative intracellular loops in pH regulation by Na^+/H^+ exchanger NHE1 显示文摘 | Hisamitsu T Yamada K Nakamura TY | 2007 | FEBS J2007，274，16： | 1 |
| 16 | Representation formulas for integrated semigroups and sine families显示文摘 | Hisamitsu Serizawa | 1992 | Aegutions Mathematical1992，44，： | 1 |
| 17 | The efficacy of dentine adhesive to sclerotic dentine显示文摘 | Kusunoki M Itoh K Hisamitsu H | 2002 | J Dent2002，30，23： | 1 |
| 18 | Immunohistochemical study of dihydropyrimidine dehydrogenase (DPD) and p53 in biopsied specimens of esophageal cancer before chemoradiotherapy显示文摘 | Hisamitsu K Fukuda K Oka S | 2001 | Gan To Kagaku Ryoho2001，28，11： | 1 |
| 19 | Glucose-responsive gel from phenylborate polymer and poly (vinyl alcohol):prompt response at physiological pH through the interaction of borate with amino group in the gel 显示文摘 | Hisamitsu I Kataoka K Okano T | 1997 | Pharm Res1997，14，3： | 1 |
| 20 | Lens culinaris agglutinin-reactive α-fetoprotein and protein induced by vitamin K absence II are potential indicators of a poor prognosis: a histopathological study of surgically resected hepatocellular carcinoma显示文摘 | Hisamitsu Miyaaki Osamu Nakashima Mina Kurogi Katsumi Eguchi Masamichi Kojiro | 2007 | Journal of Gastroenterology2007，，12： | 1 |
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