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    题名 作者 年代 出处 被引量
1气候变化对中国水资源影响的适应性评估与管理框架显示文摘通过论述气候变化对中国水资源影响的适应性评估与管理框架,提出一个气候变化影响决策评估工具,它包括:未来气候变化对中国水资源潜在影响的定性描述分析、半定量与定量分析以及适应性对策评估。由于不同气候区域所面临的水资源问题不同,选择中国4个典型案例区域,并确定不同的目标进行气候变化适应性管理综合研究,提出了甄别气候变化影响和适应性管理的新的思路、框架与方法论。该项研究为应对未来气候变化影响的水资源规划与风险管理提供了途径与方法。夏军 Thomas Tanner 任国玉 程晓陶 王金霞 王忠静 严茂超 刘晓洁 Ian Holman 2008气候变化研究进展2008,4,4:42
2早期帕金森病患者健康相关生活质量显示文摘目的研究中国早期帕金森病(PD)患者健康相关生活质量(healthrelatedqualityoflife,HR—QOL)的特点;探讨运动症状和非运动症状对早期PD患者HR—QOL的影响。方法在全国范围内共筛选出391例早期PD患者入组。采用统一帕金森病评分表(UPDRS)和Hoehn—Yahr评价运动症状,采用流行病学研究中心编制的抑郁量表(CES—D)、匹兹堡睡眠质量指数(PSQI)、疲劳量表(rss)、阿尔茨海默病评定量表的认知部分(ADAS—Cog)和便秘量表分别对抑郁、睡眠障碍、疲劳、认知功能和便秘等非运动症状进行评价;采用36条目简化医疗结局调查问卷(SF-36)评价HR—QOL。比较PD患者与同龄健康老年人SF-36分值的差异。采用逐步多元线性回归分析深入探讨各种运动及非运动症状变量对HR-QOL的影响。结果早期PD患者除SF-36躯体疼痛维度外,其余各维度分值较同龄健康老年人均下降。UPDRS第3部分分值(23.8±11.8)、Hoehn—Yahr分期(2.0±0.7)和强直分值(4.4±3.1)仅能解释SF-36总分变化的18.9%(R2=0.189)。CES—D、FSS和PSQ1分值等非运动症状变量引入回归方程后,SF-36总分可被解释的部分由18.9%增加至61.7%(R2=0.617)。并且,引入CES-D分值后,SF-36总分可被解释的部分增加了43.3%(R2=0.433)。结论PD症状严重影响早期患者的HR—QOL。运动症状对HR—QOL存在影响,但影响作用有限。抑郁、疲劳和睡眠障碍这3个非运动症状是导致早期PD患者HR—QOL恶化的主要原因。其中,抑郁症状是HR-QOL恶化的最强预测因素。临床上,应重视非运动症状,运动和非运动症状兼治,才能真正提高疗效显著改善患者的HR—QOL。秦朝晖 陈彪 张丽燕 樊文辉 孙菲 方向华 孟琛 Caroline Tanner 2009中华神经科杂志2009,42,8:42
3Elimination of tropical disease through surveillance and response显示文摘Surveillance and response represent the final crucial steps in achieving effective control and particularly elimination of communicable diseases as recognized in the area of neglected tropical diseases(NTDs),applied in increasing numbers in endemic countries with ongoing control and elimination programmers.More and more national NTD elimination initiatives are scheduled based on the innovative and effective One world-One health perspective to detect pockets of transmission and disease reintroduction.Resource-constrained countries,which carry the heaviest NTD burdens,face various challenges how to strengthen the health system as well as developing effective and novel tools for sureillance and response tailored to local settings.Surillance-response approaches take place in two different stages oralling the basic components of the sureillance response system for NTD elimination.Six different research priorities have been identified:(1)dynamic mapping of transmission,(2)near real-time capture of population dynamics,(3)modelling based on a minimum essential database/dataset,(4)implementation of mobile health(m-health)and sensitive diagnostics,(5)design of effective response packages tailored to different transmission settings and levels,and( 6)validation of approaches and responses packages.Xiao-Nong Zhou RobertBergquist Marcel Tanner 2013Infectious Diseases of Poverty2013,2,1:27
4早期帕金森病患者非运动性症状与健康相关生活质量的研究:随机对照临床试验显示文摘目的探讨早期帕金森病患者非运动性症状与健康相关生活质量的关系,以及健康相关生活质量的影响因素。方法391例原发性帕金森病患者,采用美国国立卫生研究院流行病学研究中心抑郁量表(CES—D)、匹兹堡睡眠质量指数(PSQI)、疲劳量表(FSS)、阿尔茨海默病评价量表一认知分量表(ADAS—Cog)和便秘量表(CSS)评价其抑郁、睡眠障碍、疲劳、认知障碍和便秘程度,简化36医疗结局研究量表(SF-36)评价其健康相关生活质量。结果391例患者中,抑郁、睡眠障碍、疲劳、记忆障碍和便秘者分别占37.34%(146/391)、54.73%(214/391)、40.15%(157/391)、34.78%(136/391)和46.55%(182/391)。抑郁症状者与无抑郁症状者(t=18.469,P=0.000)、睡眠障碍者与无睡眠障碍者(t=7.411,P=0.000)、疲劳者与无疲劳者(t=3.992,P=0.000)比较,SF-36总评分差异具有统计学意义;而记忆障碍者与无记忆障碍者(t=1.234,P=0.221)、便秘者与无便秘者(t=2.032,P=0.051)比较,SF-36总评分差异无统计学意义。将CES—D评分、PSQI评分和FSS评分引入回归方程,雕值由0.277增至0.649,提示SF-36总评分可被预测的部分由27.70%增至64.90%;CES.D评分不仅对SF-36总评分有预测价值,而且对8个维度评分均有预测价值(P〈0.05)。结论早期帕金森病患者普遍存在非运动性症状,其中抑郁、睡眠障碍、疲劳是导致健康相关生活质量恶化的主要原因。抑郁全面影响患者健康相关生活质量,是早期帕金森病患者健康相关生活质量恶化的最强预测因素。秦朝晖 陈彪 张丽燕 樊文辉 孙菲 刘宏军 方向华 丁晖 孟琛 Caroline Tanner 2009中国现代神经疾病杂志2009,9,3:24
5应用遥感技术快速确定鄱阳湖区钉螺孳生地的研究显示文摘目的 应用地理信息系统和遥感技术 (GIS ,RS)快速确定鄱阳湖区钉螺孳生地带及血吸虫病高危区域。方法 在鄱阳湖区内选择三个血吸虫病重度流行村周围的洲滩 ,用传统方法进行螺情调查 ,卫星定位仪 (GPS)记录有钉螺点的经纬度。运用ERDASIMAGINE软件对鄱阳湖区枯水期的卫星专题制图仪 (TM)遥感片进行计算机非监督分类 ,校正植被指数 (NDVI)和穗帽湿度变换指数 (TC)模型计算 ,并对有螺点相对应TM数据进行综合分析。结果 鄱阳湖区钉螺分布和孳生与洲滩湖草的生长状况及湿度有密切的关系 ,根据现场调查的钉螺分布图 ,有螺点主要分布在计算机非监督分类的 6、7和 8类中 ,进一步模型分析表明 :有螺点主要分布在NDVI >110和TC在 - 10~ 3之间 ,其准确率达 95 %以上。结论 本项研究提示 :运用计算机非监督分类法可大致确定 6、7和 8类为有螺植被环境 ,然后通过NDVI >110确定植被优质区为钉螺的孳生环境 ,最后通过TC =- 10~郭家钢 林丹丹 胡广汉 宁安 刘红云 吕尚标 李东 吴晓华 王蓉蓉 陈名刚 郑江 Marcel Tanner 2002中华流行病学杂志2002,23,2:23
6Surveillance-response systems: the key to elimination of tropical diseases显示文摘Tropical diseases remain a major cause of morbidity and mortality in developing countries.Although combined health efforts brought about significant improvements over the past 20 years,communities in resource-constrained settings lack the means of strengthening their environment in directions that would provide less favourable conditions for pathogens.Still,the impact of infectious diseases is declining worldwide along with progress made regarding responses to basic health problems and improving health services delivery to the most vulnerable populations.The London Declaration on Neglected Tropical Diseases(NTDs),initiated by the World Health Organization’s NTD roadmap,set out the path towards control and eventual elimination of several tropical diseases by 2020,providing an impetus for local and regional disease elimination programmes.Tropical diseases are often patchy and erratic,and there are differing priorities in resources-limited and endemic countries at various levels of their public health systems.In order to identify and prioritize strategic research on elimination of tropical diseases,the‘First Forum on Surveillance-Response System Leading to Tropical Diseases Elimination’was convened in Shanghai in June 2012.Current strategies and the NTD roadmap were reviewed,followed by discussions on how to identify and critically examine prevailing challenges and opportunities,including inter-sectoral collaboration and approaches for elimination of several infectious,tropical diseases.A priority research agenda within a‘One Health-One World’frame of global health was developed,including(i)the establishment of a platform for resource-sharing and effective surveillance-response systems for Asia Pacific and Africa with an initial focus on elimination of lymphatic filariasis,malaria and schistosomiasis;(ii)development of new strategies,tools and approaches,such as improved diagnostics and antimalarial therapies;(iii)rigorous validation of surveillance-response systems;and(iv)designing pilot studies to transfer Chinese experiences of successful surveillance-response systems to endemic countries with limited resources.Ernest Tambo Lin Ai Xia Zhou Jun-Hu Chen Wei Hu Robert Bergquist Jia-Gang Guo Jürg Utzinger Marcel Tanner Xiao-Nong Zhou 2014Infectious Diseases of Poverty2014,3,1:14
7Surveillance and response systems for elimination of tropical diseases: summary of a thematic series in Infectious Diseases of Poverty显示文摘The peer-reviewed journal Infectious Diseases of Poverty provides a new platform to engage with,and disseminate in an open-access format,science outside traditional disciplinary boundaries.The current piece reviews a thematic series on surveillance-response systems for elimination of tropical diseases.Overall,22 contributions covering a broad array of diseases are featured–i.e.clonorchiasis,dengue,hepatitis,human immunodeficiency virus/acquired immune deficiency syndrome(HIV/AIDS),H7N9 avian influenza,lymphatic filariasis,malaria,Middle East respiratory syndrome(MERS),rabies,schistosomiasis and tuberculosis(TB).There are five scoping reviews,a commentary,a letter to the editor,an opinion piece and an editorial pertaining to the theme“Elimination of tropical disease through surveillance and response”.The remaining 13 articles are original contributions mainly covering(i)drug resistance;(ii)innovation and validation in the field of mathematical modelling;(iii)elimination of infectious diseases;and(iv)social media reports on disease outbreak notifications released by national health authorities.Analysis of the authors’affiliations reveals that scientists from the People’s Republic of China(P.R.China)are prominently represented.Possible explanations include the fact that the 2012 and 2014 international conferences pertaining to surveillance-response mechanisms were both hosted by the National Institute of Parasitic Diseases(NIPD)in Shanghai,coupled with P.R.China’s growing importance with regard to the control of infectious diseases.Within 4 to 22 months of publication,three of the 22 contributions were viewed more than 10000 times each.With sustained efforts focusing on relevant and strategic information towards control and elimination of infectious diseases,Infectious Diseases of Poverty has become a leading journal in the field of surveillance and response systems in infectious diseases and beyond.Xia Zhou Peiling Yap Marcel Tanner Robert Bergquist Jürg Utzinger Xiao-Nong Zhou 2016Infectious Diseases of Poverty2016,5,1:12
8三苯双脒、青蒿琥酯、蒿甲醚和吡喹酮单剂、多剂或联合用药治疗大鼠华支睾吸虫感染的实验研究显示文摘目的观察三苯双脒、青蒿琥酯、蒿甲醚、或吡喹酮单剂、多剂给药,及其伍用治疗感染华支睾吸虫大鼠的疗效。方法147只SD大鼠各感染50个华支睾吸虫囊蚴,于感染后42~44d分组治疗。各药物采用灌胃给药。①60只感染大鼠随机分为11组(每组4~5只),分别为三苯双脒150mg/kg(顿服)、75mg/(kg·d)×2d、50mg/(kg·d)×3d和25mg/kg(tid)×2d组;吡喹酮150mg/kg(顿服)、75mg/(kg·d)×2d和25mg/kg(tid)×2d;青蒿琥酯或蒿甲醚75mg/kg(顿服)和37.5mg/(kg·d)×2d组。②另87只感染大鼠随机分为15组(每组4~6只),用青蒿琥酯或蒿甲醚(30mg/kg)分别与吡喹酮(150mg/kg)、三苯双脒(50mg/kg和75mg/kg)伍用组;三苯双脒(50mg/kg)与吡喹酮(150mg/kg)伍用组;三苯双脒(75mg/kg)与吡喹酮(187.5mg/kg)伍用组,及各药的单用组。并设同批感染未治疗对照组。受治鼠于治疗后2周剖杀,收集胆管和肝组织内的残留华支睾吸虫,计算各组的平均虫数和减虫率,用非参数统计方法(Mann-Whitney秩和检验)对相应组间的平均虫数进行分析。结果感染华支睾吸虫的大鼠口服单剂三苯双脒或吡喹酮(150mg/kg)的减虫率分别为57.2%和63.8%。三苯双脒各小剂量多次给药组的减虫率稍高,达77.1%~79.4%,而吡喹酮小剂量多次给药组的减虫率则为50.6%~54.2%。但两种药物各组间的平均虫数的差异无统计学意义。青蒿琥酯和蒿甲醚各单剂给药组与小剂量多次给药组的减虫率均较高,分别为90.4%~98.5%和100%。三苯双脒小剂量(50或75mg/kg)与吡喹酮(150mg/kg或187.5mg/kg)伍用治疗,减虫率为74.9%~100%,高于其各单药组的减虫率(26.9%~79.6%)。青蒿琥酯或蒿甲醚小剂量(30mg/kg)与吡喹酮(150mg/kg)或三苯双脒(50或75mg/kg)伍用治疗,减虫率为74.9%~97.9%,亦高于其各药组的减虫率(24.8%~79.6%)。结论青蒿琥酯、蒿甲醚、吡喹酮和三苯双脒均为有效的抗华支睾吸虫药物,各药物小剂量伍用具有增效作用。肖树华 薛剑 Marcel TANNER 张永年 Jennifer KEISER Jug UTZINGER 强慧琴 刘晓云 2008中国寄生虫学与寄生虫病杂志2008,26,5:10
9水力压裂监测新方法显示文摘深入了解水力压裂裂缝的几何形态和延伸情况有助于改善低渗油气藏压裂增产作业效果,改善油气井产能并提高油气采收率。应用地震方法对水力压裂裂缝进行监测和描述已经有多年了,而新的地震硬件和处理技术的出现使得这类监测更加有效、可靠。Les Bennett Joeol Le Calvez David R. ( Rich ) Sarver Kevin Tanner W.S.(Scott)Birk George Waters Julian Drew Gw e nola Michaud Paolo Primiero Leo Eisner Rob Jones David Leslie Michael John Williams Jim Govenlock Richard C. ( Rick ) Klein Kazuhiko Tezuka 2007国外测井技术2007,22,4:7
10蒿甲醚对感染小鼠体内埃及血吸虫皮层的损害(英文)显示文摘目的评价蒿甲醚对小鼠体内埃及血吸虫皮层的损害作用。方法8只小鼠于感染埃及血吸虫尾蚴后81d,用单剂蒿甲醚400mg/kg口服治疗。治疗后1、3、7和14d各剖杀2只小鼠,用灌注法收集血吸虫,并按常规方法固定和处置虫体,作扫描电镜观察。从另2只未作治疗的感染小鼠取虫作对照。结果用蒿甲醚治疗后24h,雄虫的皮层结节肿大、破溃或从皮层上剥落;在雄虫和雌虫的体表可查见有局灶性或广泛的皮层肿胀、融合、空泡变化、糜烂和剥落,以及感觉结构的破坏。治疗后3d,雌、雄虫的皮层损害加重,最严重的损害为口吸盘肿胀和破溃,并查见皮层褶嵴有广泛和严重的肿胀、糜烂和剥落,以及雌虫盘状感觉结构的破坏。治疗后7至14d,有些虫仍示有中或重度皮层损害,而有些仍存活的虫则示其大部分皮层已有明显恢复。结论蒿甲醚对埃及血吸虫的皮层具有广泛和严重的损害作用。肖树华 Marcel TANNER 沈炳贵 Jürg UTZINGER Jacques CHOLLET 2006中国寄生虫学与寄生虫病杂志2006,24,6:6
11Fossil charcoal from the Middle Jurassic of the Ordos Basin,China and its paleoatmospheric implications显示文摘Ordos 盆的 Yan'an 形成是四个成员的一个序列,由扔在的 siliciclastic 沉积组成冲积,湖并且淤泥背景在中间的侏罗记期间。丰富的使黑的植物材料作为炭画笔(石块炭) 通过标准分析技术识别了的从二和四包含的成员镇定的样品。在在在露头的多重地平线的河的沙岩的炭画笔的出现,在成员一的煤与 inertinite 的以前报导的高集中结合了,显示 paleowildfire 在 Yan'an 期间是在 Ordos 盆的普通出现免职。从 Yan'an 露头的沉积证据建议古气候在成员的免职期间是季节的二通过四,它可能贡献了野火频率。在 Yan'an 形成的炭画笔的存在显示大气的氧层次清楚地在在中间的侏罗记期间为持续燃烧要求的最小上面。这个结论为 paleoatmospheric 作文与以前的 geochemical 模型矛盾,但是支持更最近的研究。Lawrence H. Tanner Xin Wang Alesha C. Morabito 2012Geoscience Frontiers2012,3,4:6
12Direct laser writing of volumetric gradient index lenses and waveguides显示文摘Direct laser writing(DLW)has been shown to render 3D polymeric optical components,including lenses,beam expanders,and mirrors,with submicrometer precision.However,these printed structures are limited to the refractive index and dispersive properties of the photopolymer.Here,we present the subsurface controllable refractive index via beam exposure(SCRIBE)method,a lithographic approach that enables the tuning of the refractive index over a range of greater than 0.3 by performing DLW inside photoresist-filled nanoporous silicon and silica scaffolds.Adjusting the laser exposure during printing enables 3D submicron control of the polymer infilling and thus the refractive index and chromatic dispersion.Combining SCRIBE’s unprecedented index range and 3D writing accuracy has realized the world’s smallest(15μm diameter)spherical Luneburg lens operating at visible wavelengths.SCRIBE’s ability to tune the chromatic dispersion alongside the refractive index was leveraged to render achromatic doublets in a single printing step,eliminating the need for multiple photoresins and writing sequences.SCRIBE also has the potential to form multicomponent optics by cascading optical elements within a scaffold.As a demonstration,stacked focusing structures that generate photonic nanojets were fabricated inside porous silicon.Finally,an all-pass ring resonator was coupled to a subsurface 3D waveguide.The measured quality factor of 4600 at 1550 nm suggests the possibility of compact photonic systems with optical interconnects that traverse multiple planes.SCRIBE is uniquely suited for constructing such photonic integrated circuits due to its ability to integrate multiple optical components,including lenses and waveguides,without additional printed supports.Christian R.Ocier Corey A.Richards Daniel A.Bacon-Brown Qing Ding Raman Kumar Tanner J.Garcia Jorik van de Groep Jung-Hwan Song Austin J.Cyphersmith Andrew Rhode Andrea N.Perry Alexander J.Littlefield Jinlong Zhu Dajie Xie Haibo Gao Jonah F.Messinger Mark L.Brongersma Kimani C.Toussaint Jr Lynford L.Goddard Paul V.Braun 2020Light(Science & Applications)2020,9,1:6
13一种应用遥感技术快速确定鄱阳湖区有螺洲滩的方法(英文)显示文摘目的 应用地理信息系统 /遥感技术 (GIS/ RS)快速确定鄱阳湖区钉螺孳生地带及血吸虫病高危区域。 方法 选择鄱阳湖区内 3个洲岛型血吸病重度流行村周围的洲滩地图进行数字化 ,在数字化地图的基础上分别对两张 L andsat5 (洪水期和沽水期 ) TM卫星遥感片进行校正 ,并提取出冬陆夏水洲滩部分 ,运用 ERDAS IMAGINE软件对此洲滩进行计算机非监督分类 (U nsu-pervised Classification)、校正植被指数 (Normalized Difference Vegetation Index,NDVI)和穗帽湿度变换指数 (Tasseled Cap,TC)模型计算 ;用传统方法进行螺情调查 ,卫星定位仪 (GPS)记录有钉螺点的经纬度 ,同时选择部分堤内的农田和水溏 (无螺区 )作为对照点。 结果 用计算机非监督分类共分为 10类 ,根据现场调查的钉螺分布图 ,有螺点主要分布在计算机非监督分类的 6、7和 8类中 ,进一步模型分析表明 ,有螺点主要分布在校正植被指数 NDVI>115和穗帽湿度变换指数 TC在 - 10到 3之间 ,而堤内农田和水溏等对照点中的值则主要分布此数值以外。 结论 鄱阳湖区钉螺分布和孳生与洲滩湖草的生长状况与及湿度有着密切的关系 ,本项研究提示 ,运用计算机非监督分类法可大致确定 6、7和 8类为有螺植被环境 ,然后通过校正植被指数 (NDVI>110 )郭家钢 陈红根 林丹丹 胡广汉 吴晓华 李东 刘红云 郑江 陈名刚 Marcel Tanner 2002中国寄生虫病防治杂志2002,15,5:3
14演奏的力量--李斯特《b小调奏鸣曲》结构与演奏分析显示文摘从作品的曲式结构内在的模糊性、标题内容与形式的辨证关系、演奏与理论分析之间相辅相成的关系以及演奏者与听众的互动等各个不同角度出发,对李斯特的音响上和文字上的诠释进行综合分析、比较.马克·田纳(Mark Tanner) 毕丽君 2004艺术探索2004,18,6:2
15Hamartoma of CNS associated with precocious puberty显示文摘Zunigz O F Tanner S M Wild W O 1983Am J Dis Child1983,137,2:2
16Schistosomiasis and water resources development: systematic review, meta-analysis, and estimates of people at risk显示文摘Peter Steinmann Jennifer Keiser Robert Bos Marcel Tanner Jürg Utzinger 2006The Lancet Infectious Diseases2006,,7:2
17搀杂镧系离子的纳米绝缘材料的合成与发光特性(英文)显示文摘The general characteristics of f-f and f-d emission spectra of lanthanide ions in insulators are discussed. The current status of energy level and intensity calculations is evaluated. Taking typical examples, the methods of synthesis of lanthanide ion-doped insulating nanomaterials are presented and their characterizations and unusual optical properties are compared.P.A. Tanner 2005光散射学报2005,17,3:2
18In vitro and in vivo evaluation of polyhydroxybutyrate reinforced with hydroxyapatite显示文摘Doyle C Tanner E T Bonfield W 1991Biomaterials1991,12,:2
19Orderly‐Layered Tetravalent Manganese‐Doped Strontium Aluminate Sr 4 Al 14 O 25: Mn 4+: An Efficient Red Phosphor for Warm White Light Emitting Diodes显示文摘Mingying Peng Xuewen Yin Peter A. Tanner Chuqi Liang Pengfei Li Qinyuan Zhang Jianrong Qiu 2013J. Am. Ceram. Soc2013,,9:2
20Recent progress in thermoelectric nanocomposites based on solution-synthesized nanoheterostructures显示文摘热电的材料,能把浪费热变换成电,接受了在最近的年里增加研究兴趣。这篇论文基于综合答案的 nanoheterostructures 在热电的 nanocomposites 描述最近的进步。我们以由使用 nanoheterostructures 改进给定的材料的力量因素的策略开始我们的讨论。然后,我们讨论减少的热电导率的方法。最后,也就是,我们加亮去耦力量因素和热电导率的一个方法把阶段转变材料合并到 nanowire heterostructure。我们探索了铅碲化物铜碲化物在这个工作的热电的 nanowire heterostructure。改进优点的数字的未来可能的方法在这篇论文的结束被讨论。Wei Zheng Biao Xu Lin Zhou Yilong Zhou Haimei Zheng Chenghan Sun Enzheng Shi Tanner Dale Fink Yue Wu 2017Nano Research2017,10,5:2
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