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| 1 | Neuroimage-Based Consciousness Evaluation of Patients with Secondary Doubtful Hydrocephalus Before and After Lumbar Drainage显示文摘Hydrocephalus is often treated with a cerebrospinal fluid shunt(CFS) for excessive amounts of cerebrospinal fluid in the brain.However,it is very difficult to distinguish whether the ventricular enlargement is due to hydrocephalus or other causes,such as brain atrophy after brain damage and surgery.The non-trivial evaluation of the consciousness level,along with a continuous drainage test of the lumbar cistern is thus clinically important before the decision for CFS is made.We studied 32 secondary mild hydrocephalus patients with different consciousness levels,who received T1 and diffusion tensor imaging magnetic resonance scans before and after lumbar cerebrospinal fluid drainage.We applied a novel machine-learning method to find the most discriminative features from the multi-modal neuroimages.Then,we built a regression model to regress the JFK Coma Recovery Scale-Revised(CRS-R) scores to quantify the level of consciousness.The experimental results showed that our method not only approximated the CRS-R scores but also tracked the temporal changes in individual patients.The regression model has high potential for the evaluation of consciousness in clinical practice. | Jiayu Huo Zengxin Qi Sen Chen Qian Wang Xuehai Wu Di Zang Tanikawa Hiromi Jiaxing Tan Lichi Zhang Weijun Tang Dinggang Shen | 2020 | Neuroscience Bulletin2020，36，9： | 7 |
| 2 | 近红外漫射光层析成像实验研究显示文摘实验验证了所建立的时间分辨光学层析成像测量系统的光学参量预测能力、多个测量通道的一致性,表明了本测量系统具有层析成像的潜力.研究了采用特征数据量(平均飞行时间、广义脉冲谱技术为基础的用数据类型R)及全时间分辨数据的图像重建算法在光学参量重建准确度、重建出的对象尺寸、空间分辨率等方面的各自优势. | 赵会娟 姜颖婷 缪辉 高峰 YUKARI Tanikawa YUKIO Yamada | 2007 | 光子学报2007，36，6： | 6 |
| 3 | Clinicopathologic Analysis of Combined Hepatocellular-Cholangiocarcinoma According to the Latest WHO Classification显示文摘 | Jun Akiba Osamu Nakashima Satoshi Hattori Ken Tanikawa Miki Takenaka Masamich Nakayama Reiichiro Kondo Yoriko Nomura Keiko Koura Kousuke Ueda Sakiko Sanada Yoshiki Naito Rin Yamaguchi Hirohisa Yano | 2013 | The American Journal of Surgical Pathology2013，，4： | 3 |
| 4 | Endoscopic papillectomy of minor papillar adenoma associated with pancreas divisum显示文摘Tumors of the minor papilla of the duodenum are quite rare.We successfully and safely treated an 18-mm adenoma of the minor papilla associated with pancreas divisum using endoscopic papillectomy.A 64-year-old man was admitted to our hospital for treatment of an asymptomatic mass in the minor papilla detected by upper gastrointestinal endoscopy.Endscopic analysis showed an 18-mm,whitish,sessile mass,located in the duodenum proximal to a normal-appearing major papilla.Endoscopic retrograde pancreatography did not reveal the pancreatic duct.Magnetic resonance cholangiopancreatography showed a lack of the ventral pancreatic duct.We suspected this case was associated with pancreatic divisum;therefore,we performed endoscopic papillectomy of the minor papilla tumor.Subsequently,endoscopic pancreatic stent placement in the minor papilla was done to prevent drainage disturbance.The patient has been asymptomatic without recurrence of tumor or stenosis of the Santorini orifice upon endoscopic examination for the past 2 years. | Akira Kanamori Takashi Kumada Seiki Kiriyama Yasuhiro Sone Makoto Tanikawa Yasuhiro Hisanaga Hidenori Toyoda Hiroki Kawashima Akihiro Itoh Yoshiki Hirooka Hidemi Goto | 2009 | World Journal of Gastroenterology2009，15，9： | 2 |
| 5 | Endoscopy-based Kyoto classification score of gastritis related to pathological topography of neutrophil activity显示文摘BACKGROUND Endoscopy-based Kyoto classification for gastritis and pathological topographic distribution of neutrophil infiltration are correlated with gastric cancer risk.AIM To investigate the association between Kyoto classification and the topographic distribution of neutrophil activity.METHODS Kyoto classification score,ranging from 0 to 8,consisted of atrophy,intestinal metaplasia,enlarged folds,nodularity,and diffuse redness.Neutrophil activity was scored according to the updated Sydney System using biopsy samples obtained from the greater curvature of the corpus and the antrum.The participants were divided into four categories,inactive stomach,antrumpredominant gastritis,pangastritis,and corpus-predominant gastritis,based on the topographic distribution of neutrophil activity.Effects of sex,age,body mass index,drinking habit,smoking habit,family history of gastric cancer,serum Helicobacter pylori(H.pylori)antibody,and Kyoto score on topography of neutrophil infiltration were analyzed.RESULTS A total of 327 patients(comprising 50.7%women,with an average age of 50.2 years)were enrolled in this study.H.pylori infection rate was 82.9%with a mean Kyoto score of 4.63.The Kyoto score was associated with the topographic distribution of neutrophil activity.Kyoto scores were significantly higher in the order of inactive stomach,antrum-predominant gastritis,pangastritis,and corpuspredominant gastritis(3.05,4.57,5.21,and 5.96,respectively).Each individual score of endoscopic findings(i.e.,atrophy,intestinal metaplasia,enlarged folds,nodularity,and diffuse redness)was correlated with the topographic distribution of neutrophil activity.On multivariate analysis,the Kyoto score,age,and serum H.pylori antibody were independently associated with the topographic distribution of neutrophil activity.CONCLUSION The Kyoto classification score was associated with the topographic distribution of neutrophil activity. | Osamu Toyoshima Toshihiro Nishizawa Shuntaro Yoshida Yoshiki Sakaguchi Yousuke Nakai Hidenobu Watanabe Hidekazu Suzuki Chizu Tanikawa Koichi Matsuda Kazuhiko Koike | 2020 | World Journal of Gastroenterology2020，26，34： | 2 |
| 6 | Long-term use of entecavir in nucleoside-na?ve Japanese patients with chronic hepatitis B infection显示文摘 | Osamu Yokosuka Koichi Takaguchi Shinichi Fujioka Michiko Shindo Kazuaki Chayama Haruhiko Kobashi Norio Hayashi Chifumi Sato Kendo Kiyosawa Kyuichi Tanikawa Hiroki Ishikawa Nobuyuki Masaki Taku Seriu Masao Omata | 2010 | Journal of Hepatology2010，，6： | 2 |
| 7 | Basic fibroblast growth factor regulates proliferation and motility of human hepatoma cells by an autocrine mechanism显示文摘 | Motoaki Kin Michio Sata Takato Ueno Takuji Torimura Sadataka Inuzuka Riko Tsuji Kodo Sujaku Masaharu Sakamoto Hiroshi Sugawara Seisyu Tamaki Kyuichi Tanikawa | 1997 | Journal of Hepatology1997，，4： | 2 |
| 8 | Vascular endothelial growth factor expression and neovaseularisation in non-small cell lung cancer 显示文摘 | Yano T Tanikawa S Fujie T | 2000 | EurJ Cancer2000，36，5： | 1 |
| 9 | An external surface coating to protect concrete and steel from aggressive environments 显示文摘 | SWAMY R TANIKAWA S | 1993 | Mater Struct1993，260，10： | 1 |
| 10 | Phylogenetie rela- tionships of rat lungworm, Angiostrongylus cantonensis, isolated from different geographical regions revealed widespread multiple lineages显示文摘 | Tokiwa T Harunari T Tanikawa T et ol | 2012 | Parasitol Int2012，61，3： | 1 |
| 11 | Japanese guidelines for the management of pemphigus显示文摘 | Amagai M Tanikawa A Shimizu T | 2014 | J Dermatol2014，41，6： | 1 |
| 12 | T helper type 2- biased natural killer cell phenotype in patients with pemphigus vulgaris 显示文摘 | Takahashi H Amagai M Tanikawa A | 2007 | J Invest Dermatol2007，127，2： | 1 |
| 13 | Sequential analysis of recurrent calcium calculi by infrared spectroscopy 显示文摘 | Matsuzaki S Matsushita K Tanikawa K | 1995 | Int J Urol1995，2，： | 1 |
| 14 | Orphan receptor tyrosine kinase ROR2as a potential therapeutic target for osteosarcoma显示文摘 | Morioka K Tanikawa C Ochi K | 2009 | Cancer Sci2009，100，： | 1 |
| 15 | Suppression of Cyp3A2mRNA expression in the Warfarin resistance foor rat, Rattus rattus: possible involvement P450 in the Warfarin resistance mechanism 显示文摘 | Sugano S Kobayashi T Tanikawa T | 2001 | Xeno Bilotiea2001，7，： | 1 |
| 16 | Time- resolved diffuse optical tomography using a modified generalized pulse spectrum technique 显示文摘 | Gao Feng Zhao Huijuan Tanikawa Y | 2002 | leice Transac- tions on Information and Systems2002，85，1： | 1 |
| 17 | Vascular endothelial growth factor expression and neovascularisation in non-small cell lung cancer 显示文摘 | Yano T Tanikawa S Fujie T | 2000 | Eur J Cancer2000，36，5： | 1 |
| 18 | Wnt-1 signal indulges phosphorylation and degradation of c-Myb protein via TAK1, H1PK2, and NLK 显示文摘 | Kanei-lshii C Ninomiya-Tsuji J Tanikawa J | 2004 | Genes Dev2004，18，7： | 1 |
| 19 | Clinicalevaluation of the effect of daio(Rheirhizoma)on the progression of diabetic nephropathy with overt proteinuria显示文摘 | Goto H Shimada Y Tanikawa K | 2003 | Am J Chin Med2003，31，： | 1 |
| 20 | A long-term investigation of transcatheter splenic arterial embolization for hypersplenism显示文摘 | Sakata K Hirai K Tanikawa K | 1996 | Hepat ogast roenteroiogy1996，43，7： | 1 |
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